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Page 1
Associations of healthy lifestyle and genetic susceptibility with risks of osteoarthritis: A prospective cohort study.
Chen S, Zhang Y, Fan T, Zeng M, Yang Q, Yang H, Fang X, Jin X, Cao P, Wang Z, Zhang Y, Hunter DJ, Zhou Y; GO consortium; arcOGEN Consortium, HUNT All-In Pain, ARGO Consortium, Regeneron Genetics Center; Ding C, Zhu Z. Chen S, et al. Rheumatology (Oxford). 2025 Jun 20:keaf327. doi: 10.1093/rheumatology/keaf327. Online ahead of print. Rheumatology (Oxford). 2025. PMID: 40578805
Translational genomics of osteoarthritis in 1,962,069 individuals.
Hatzikotoulas K, Southam L, Stefansdottir L, Boer CG, McDonald ML, Pett JP, Park YC, Tuerlings M, Mulders R, Barysenka A, Arruda AL, Tragante V, Rocco A, Bittner N, Chen S, Horn S, Srinivasasainagendra V, To K, Katsoula G, Kreitmaier P, Tenghe AMM, Gilly A, Arbeeva L, Chen LG, de Pins AM, Dochtermann D, Henkel C, Höijer J, Ito S, Lind PA, Lukusa-Sawalena B, Minn AKK, Mola-Caminal M, Narita A, Nguyen C, Reimann E, Silberstein MD, Skogholt AH, Tiwari HK, Yau MS, Yue M, Zhao W, Zhou JJ, Alexiadis G, Banasik K, Brunak S, Campbell A, Cheung JTS, Dowsett J, Faquih T, Faul JD, Fei L, Fenstad AM, Funayama T, Gabrielsen ME, Gocho C, Gromov K, Hansen T, Hudjashov G, Ingvarsson T, Johnson JS, Jonsson H, Kakehi S, Karjalainen J, Kasbohm E, Lemmelä S, Lin K, Liu X, Loef M, Mangino M, McCartney D, Millwood IY, Richman J, Roberts MB, Ryan KA, Samartzis D, Shivakumar M, Skou ST, Sugimoto S, Suzuki K, Takuwa H, Teder-Laving M, Thomas L, Tomizuka K, Turman C, Weiss S, Wu TT, Zengini E, Zhang Y; arcOGEN Consortium; ARGO Consortium; DBDS Genomic Consortium; Estonian Biobank Research Team; FinnGen; Genes & Health Research Team; HUNT All-In Pain; Million Veteran Program; Regeneron Genetics C… See abstract for full author list ➔ Hatzikotoulas K, et al. Among authors: tuerlings m. Nature. 2025 May;641(8065):1217-1224. doi: 10.1038/s41586-025-08771-z. Epub 2025 Apr 9. Nature. 2025. PMID: 40205036 Free PMC article.
A human in vitro 3D neo-cartilage model to explore the response of OA risk genes to hyper-physiological mechanical stress.
Timmermans RGM, Bloks NGC, Tuerlings M, van Hoolwerff M, Nelissen RGHH, van der Wal RJP, van der Kraan PM, Blom AB, van den Bosch MHJ, Ramos YFM, Meulenbelt I. Timmermans RGM, et al. Among authors: tuerlings m. Osteoarthr Cartil Open. 2021 Dec 25;4(1):100231. doi: 10.1016/j.ocarto.2021.100231. eCollection 2022 Mar. Osteoarthr Cartil Open. 2021. PMID: 36474468 Free PMC article.
WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes.
Tuerlings M, Janssen GMC, Boone I, van Hoolwerff M, Rodriguez Ruiz A, Houtman E, Suchiman HED, van der Wal RJP, Nelissen RGHH, Coutinho de Almeida R, van Veelen PA, Ramos YFM, Meulenbelt I. Tuerlings M, et al. Osteoarthritis Cartilage. 2023 Jan;31(1):39-48. doi: 10.1016/j.joca.2022.09.009. Epub 2022 Oct 5. Osteoarthritis Cartilage. 2023. PMID: 36208715 Free article.
Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants.
van Hoolwerff M, Tuerlings M, Wijnen IJL, Suchiman HED, Cats D, Mei H, Nelissen RGHH, van der Linden-van der Zwaag HMJ, Ramos YFM, Coutinho de Almeida R, Meulenbelt I. van Hoolwerff M, et al. Among authors: tuerlings m. Rheumatology (Oxford). 2023 Feb 1;62(2):894-904. doi: 10.1093/rheumatology/keac272. Rheumatology (Oxford). 2023. PMID: 35532170 Free PMC article.
Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology.
Bjornsdottir G, Stefansdottir L, Thorleifsson G, Sulem P, Norland K, Ferkingstad E, Oddsson A, Zink F, Lund SH, Nawaz MS, Bragi Walters G, Skuladottir AT, Gudjonsson SA, Einarsson G, Halldorsson GH, Bjarnadottir V, Sveinbjornsson G, Helgadottir A, Styrkarsdottir U, Gudmundsson LJ, Pedersen OB, Hansen TF, Werge T, Banasik K, Troelsen A, Skou ST, Thørner LW, Erikstrup C, Nielsen KR, Mikkelsen S; DBDS Genetic Consortium; GO Consortium; Jonsdottir I, Bjornsson A, Olafsson IH, Ulfarsson E, Blondal J, Vikingsson A, Brunak S, Ostrowski SR, Ullum H, Thorsteinsdottir U, Stefansson H, Gudbjartsson DF, Thorgeirsson TE, Stefansson K. Bjornsdottir G, et al. Nat Commun. 2022 Apr 27;13(1):2419. doi: 10.1038/s41467-022-30129-6. Nat Commun. 2022. PMID: 35477715 Free PMC article. No abstract available.
24 results