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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1986 1
1991 1
1993 1
1995 1
1997 2
1998 3
1999 2
2000 5
2001 6
2002 10
2003 10
2004 16
2005 37
2006 42
2007 38
2008 59
2009 68
2010 94
2011 108
2012 147
2013 236
2014 369
2015 489
2016 617
2017 783
2018 1082
2019 1411
2020 1750
2021 1958
2022 2082
2023 1877
2024 487

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12,368 results

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Page 1
Stiff matrix induces exosome secretion to promote tumour growth.
Wu B, Liu DA, Guan L, Myint PK, Chin L, Dang H, Xu Y, Ren J, Li T, Yu Z, Jabban S, Mills GB, Nukpezah J, Chen YH, Furth EE, Gimotty PA, Wells RG, Weaver VM, Radhakrishnan R, Wang XW, Guo W. Wu B, et al. Nat Cell Biol. 2023 Mar;25(3):415-424. doi: 10.1038/s41556-023-01092-1. Epub 2023 Feb 16. Nat Cell Biol. 2023. PMID: 36797475 Free PMC article.
We delineate a molecular pathway that links stiff ECM to activation of Akt, which in turn promotes GTP loading to Rab8 that drives exosome secretion. We further show that exosomes generated from cells grown on stiff ECM effectively promote tumour growth. ...O …
We delineate a molecular pathway that links stiff ECM to activation of Akt, which in turn promotes GTP loading to Rab8 that drives exosom
Exosome and exosomal microRNA: trafficking, sorting, and function.
Zhang J, Li S, Li L, Li M, Guo C, Yao J, Mi S. Zhang J, et al. Genomics Proteomics Bioinformatics. 2015 Feb;13(1):17-24. doi: 10.1016/j.gpb.2015.02.001. Epub 2015 Feb 24. Genomics Proteomics Bioinformatics. 2015. PMID: 25724326 Free PMC article. Review.
This suggests an active sorting mechanism of exosomal miRNAs, since the miRNA profiles of exosomes may differ from those of the parent cells. ...In this review, we will introduce the origin and the trafficking of exosomes between cells, display current resear …
This suggests an active sorting mechanism of exosomal miRNAs, since the miRNA profiles of exosomes may differ from those of th …
Exosome-Mediated Metastasis: Communication from a Distance.
Wortzel I, Dror S, Kenific CM, Lyden D. Wortzel I, et al. Dev Cell. 2019 May 6;49(3):347-360. doi: 10.1016/j.devcel.2019.04.011. Dev Cell. 2019. PMID: 31063754 Free article. Review.
Cell-cell communication via extracellular vesicles (exosomes and microvesicles) between primary tumor cells and the microenvironment of distant organs is crucial for pre-metastatic niche (PMN) formation and metastasis. Here, we review work on the contribution of …
Cell-cell communication via extracellular vesicles (exosomes and microvesicles) between primary tumor cells and the microenvir …
Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma.
Zhang X, Xu Y, Ma L, Yu K, Niu Y, Xu X, Shi Y, Guo S, Xue X, Wang Y, Qiu S, Cui J, Wang H, Tian X, Miao Y, Meng F, Qiao Y, Yu Y, Wang J. Zhang X, et al. Cancer Commun (Lond). 2022 Apr;42(4):287-313. doi: 10.1002/cac2.12275. Epub 2022 Feb 20. Cancer Commun (Lond). 2022. PMID: 35184419 Free PMC article.
METHODS: Established human lung fibroblasts MRC-5, WI38, and human LUAD H1650, PC9, H1975, H358, A549, and H1299 cell lines, tumor and matched normal adjacent tissues of LUAD, and plasma from healthy individuals and LUAD patients were used in this study. ...Notably, the ro …
METHODS: Established human lung fibroblasts MRC-5, WI38, and human LUAD H1650, PC9, H1975, H358, A549, and H1299 cell lines, tumor an …
Advances in Exosome-Based Drug Delivery and Tumor Targeting: From Tissue Distribution to Intracellular Fate.
Shao J, Zaro J, Shen Y. Shao J, et al. Int J Nanomedicine. 2020 Nov 24;15:9355-9371. doi: 10.2147/IJN.S281890. eCollection 2020. Int J Nanomedicine. 2020. PMID: 33262592 Free PMC article. Review.
Endogenous exosomes function as signalosomes since they convey signals via ligands or adhesion molecules located on the exosomal membrane, or packaged inside the exosome. ...Exosomes, specifically tumor cell-derived exosomes, are presumed …
Endogenous exosomes function as signalosomes since they convey signals via ligands or adhesion molecules located on the exosomal
Exosome detection via surface-enhanced Raman spectroscopy for cancer diagnosis.
Li J, Li Y, Li P, Zhang Y, Du L, Wang Y, Zhang C, Wang C. Li J, et al. Acta Biomater. 2022 May;144:1-14. doi: 10.1016/j.actbio.2022.03.036. Epub 2022 Mar 28. Acta Biomater. 2022. PMID: 35358734 Free article. Review.
Studies have shown that tumor-derived exosomes can carry a variety of primary tumor-specific molecules, which may represent a novel tool for the early detection of cancer. However, the clinical translation of exosomes remains a challenge due to the req …
Studies have shown that tumor-derived exosomes can carry a variety of primary tumor-specific molecules, which may repre …
Expression, regulation, and function of exosome-derived miRNAs in cancer progression and therapy.
Li B, Cao Y, Sun M, Feng H. Li B, et al. FASEB J. 2021 Oct;35(10):e21916. doi: 10.1096/fj.202100294RR. FASEB J. 2021. PMID: 34510546 Review.
We address the biological functions of exosome-derived miRNAs in processes such as tumor-cell proliferation, angiogenesis, metastasis, and chemoresistance in the tumor microenvironment. ...We consider therapeutic miRNA-based nanoparticles, which are widely ex …
We address the biological functions of exosome-derived miRNAs in processes such as tumor-cell proliferation, angiogenesis, met …
Challenges in Exosome Isolation and Analysis in Health and Disease.
Ludwig N, Whiteside TL, Reichert TE. Ludwig N, et al. Int J Mol Sci. 2019 Sep 21;20(19):4684. doi: 10.3390/ijms20194684. Int J Mol Sci. 2019. PMID: 31546622 Free PMC article. Review.
Although many novel approaches to exosome isolation and analysis of their cargos have been introduced, the role of exosomes as diagnostic or prognostic biomarkers of disease remains unconfirmed. This review considers existing challenges to exosome validation …
Although many novel approaches to exosome isolation and analysis of their cargos have been introduced, the role of exosomes as …
Exosome in tumour microenvironment: overview of the crosstalk between normal and cancer cells.
Roma-Rodrigues C, Fernandes AR, Baptista PV. Roma-Rodrigues C, et al. Biomed Res Int. 2014;2014:179486. doi: 10.1155/2014/179486. Epub 2014 May 21. Biomed Res Int. 2014. PMID: 24963475 Free PMC article. Review.
Cancer development is a multistep process in which exosomes play important roles. Exosomes are small vesicles formed in vesicular bodies in the endosomal network. ...Cancer derived exosomes (CCEs) are important players in the formation of the tumour mi …
Cancer development is a multistep process in which exosomes play important roles. Exosomes are small vesicles formed in vesicu …
Exosomes in cancer development, metastasis, and immunity.
Zhang L, Yu D. Zhang L, et al. Biochim Biophys Acta Rev Cancer. 2019 Apr;1871(2):455-468. doi: 10.1016/j.bbcan.2019.04.004. Epub 2019 Apr 30. Biochim Biophys Acta Rev Cancer. 2019. PMID: 31047959 Free PMC article. Review.
In this review, we summarize the functions of exosomes in cancer development, metastasis, and anti-tumor or pro-tumor immunity, plus their application in cancer treatment and diagnosis/prognosis. Although the exosome field has rapidly advanced, we stil …
In this review, we summarize the functions of exosomes in cancer development, metastasis, and anti-tumor or pro-tumor i …
12,368 results
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