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Year Number of Results
1996 1
1999 1
2000 3
2001 1
2002 1
2003 5
2004 5
2005 11
2006 12
2007 16
2008 9
2009 10
2010 7
2011 5
2012 8
2013 7
2014 9
2015 7
2016 6
2017 10
2018 4
2019 5
2020 6
2021 3
2022 0
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133 results
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Pretreatment of simvastatin on liver trace element levels during endotoxemia.
Yorulmaz H, Ozkok E, Demir G, Ertugrul Yalcin I, Ates G, Olgac V, Tamer S. Yorulmaz H, et al. Arch Physiol Biochem. 2020 Jul;126(3):196-200. doi: 10.1080/13813455.2018.1508234. Epub 2018 Nov 17. Arch Physiol Biochem. 2020. PMID: 30450988
Rats were divided into control, LPS, simvastatin, and simvastatin + LPS. The histopathologic examination of the liver was performed using hematoxylin and eosin. ...Levels of selenium, and copper significantly decreased in both of LPS and simvastatin + LPS. In …
Rats were divided into control, LPS, simvastatin, and simvastatin + LPS. The histopathologic examination of the liver was perf …
Can the Combination of Simvastatin and Melatonin Create a Synergistic Effect on Bone Regeneration?
Koç O, Tüz HH, Ocak M, Bilecenoğlu B, Fırat A, Kaymaz FF. Koç O, et al. J Oral Maxillofac Surg. 2021 Aug;79(8):1672-1682. doi: 10.1016/j.joms.2020.12.044. Epub 2021 Jan 5. J Oral Maxillofac Surg. 2021. PMID: 33524327
The following were administered into critical-sized calvarial defects of the rats: Group I-human allograft; Group II-human allograft + 10 mg melatonin; Group III-human allograft + 0.1 mg simvastatin; and Group IV-human allograft + 10 mg melatonin + 0.1 mg simvastatin …
The following were administered into critical-sized calvarial defects of the rats: Group I-human allograft; Group II-human allograft + 10 mg …
Effects of simvastatin on matrix metalloproteinase regulation in IL-1beta-induced SW1353 cells.
Cecen B, Keles D, Oktay G, Kozaci LD. Cecen B, et al. Chem Biol Interact. 2019 Sep 1;310:108730. doi: 10.1016/j.cbi.2019.108730. Epub 2019 Jun 28. Chem Biol Interact. 2019. PMID: 31260663
Effects of simvastatin on cell viability and cytotoxicity of chondrocytes were measured with WST-1 and lactate dehydrogenase (LDH) assays, respectively. Under inflammatory conditions, in the absence/presence of simvastatin, the changes in matrix metalloproteinases ( …
Effects of simvastatin on cell viability and cytotoxicity of chondrocytes were measured with WST-1 and lactate dehydrogenase (LDH) as …
Pharmacokinetics of orally administered simvastatin in turkeys.
Jasiecka A, Grabowski T, Maślanka T, Ziółkowski H, Jaroszewski JJ. Jasiecka A, et al. Pol J Vet Sci. 2013;16(2):377-9. doi: 10.2478/pjvs-2013-0050. Pol J Vet Sci. 2013. PMID: 23971207 Clinical Trial.
The aim of the present study was to determine the pharmacokinetics of simvastatin (SIM) administered orally in 6-week-old turkeys at a single dose of 2 mg/kg b.w. ...The results indicate that the SIM is absorbed from the gastrointestinal tract of turkeys; how …
The aim of the present study was to determine the pharmacokinetics of simvastatin (SIM) administered orally in 6-week-old turkeys …
The Effect of Simvastatin on Pulmonary Damage in Experimental Peritonitis in Rats.
Altunal C, Agalar F, Agalar C, Daphan C, Saygun O, Aydinuraz K, Sahiner T, Atasoy P, Caglayan O, Dom S. Altunal C, et al. Indian J Surg. 2015 Dec;77(Suppl 2):370-5. doi: 10.1007/s12262-013-0845-0. Epub 2013 Feb 1. Indian J Surg. 2015. PMID: 26730028 Free PMC article.
Forty Wistar albino rats were divided into four groups. In sham group, laparotomy was the standard procedure. In simvastatin group, simvastatin was given perorally before laparotomy. In sepsis group, peritoneal sepsis was constituted by cecal ligation and puncture t …
Forty Wistar albino rats were divided into four groups. In sham group, laparotomy was the standard procedure. In simvastatin group, …
Interaction of the cholesterol reducing agent simvastatin with zwitterionic DPPC and charged DPPG phospholipid membranes.
Sariisik E, Koçak M, Kucuk Baloglu F, Severcan F. Sariisik E, et al. Biochim Biophys Acta Biomembr. 2019 Apr 1;1861(4):810-818. doi: 10.1016/j.bbamem.2019.01.014. Epub 2019 Jan 29. Biochim Biophys Acta Biomembr. 2019. PMID: 30707888 Free article.
Simvastatin is a lipid-lowering drug in the pharmaceutical group statins. ...The FTIR results indicate that the effect of simvastatin on membrane structure and dynamics depends on the type of membrane lipids. ...
Simvastatin is a lipid-lowering drug in the pharmaceutical group statins. ...The FTIR results indicate that the effect of simvasta …
Therapeutic effects of simvastatin on Galectin-3 and oxidative stress parameters in endotoxemic lung tissue.
Yorulmaz H, Ozkok E, Kaptan E, Ates G, Tamer S. Yorulmaz H, et al. Biosci Rep. 2018 Jun 27;38(3):BSR20180308. doi: 10.1042/BSR20180308. Print 2018 Jun 29. Biosci Rep. 2018. PMID: 29853535 Free PMC article.
Rats were divided into four groups as the control, LPS (20 mg/kg), simvastatin (20 mg/kg), and simvastatin+LPS group. Galectin-3 expression in formalin-fixed paraffin-embedded lung tissue sections was demonstrated by using the immunohistochemistry methods. ...Howeve …
Rats were divided into four groups as the control, LPS (20 mg/kg), simvastatin (20 mg/kg), and simvastatin+LPS group. Galectin …
Autogenous Tooth Bone Graft and Simvastatin Combination Effect on Bone Healing.
Taşdemir U, Kirtay M, Keleş A, Çil N, Abban G, Dodurga Y. Taşdemir U, et al. J Craniofac Surg. 2020 Nov/Dec;31(8):2350-2354. doi: 10.1097/SCS.0000000000006707. J Craniofac Surg. 2020. PMID: 33136889
The defects were grafted only with ATGM in Group 1, with ATGM mixed with simvastatin in Group 2, autogenous bone graft mixed with simvastatin in Group 3, and with xenogenic bone graft mixed with simvastatin in Group 4. ...Autogenous mineralized tooth bone gra …
The defects were grafted only with ATGM in Group 1, with ATGM mixed with simvastatin in Group 2, autogenous bone graft mixed with …
The impact of pretreatment with simvastatin on kidney tissue of rats with acute sepsis.
Özkök E, Yorulmaz H, Ateş G, Aydın I, Ergüven M, Tamer Ş. Özkök E, et al. Physiol Int. 2017 Jun 1;104(2):158-170. doi: 10.1556/2060.104.2017.2.8. Physiol Int. 2017. PMID: 28665194 Free article.
Rats were separated into four groups, namely, control, lipopolysaccharides (LPS) (20 mg/kg), simvastatin (20 mg/kg), and simvastatin + LPS. We measured the levels of mitochondrial enzyme activities and TBARS in the kidney using spectrophotometry. ...In tissue, TNF-a …
Rats were separated into four groups, namely, control, lipopolysaccharides (LPS) (20 mg/kg), simvastatin (20 mg/kg), and simvastat …
Role of simvastatin and RORalpha activity in the macrophage apoptotic pathway.
Çoban N, Güleç Ç, Özsait Selçuk B, Erginel-Ünaltuna N. Çoban N, et al. Anatol J Cardiol. 2017 May;17(5):362-366. doi: 10.14744/AnatolJCardiol.2016.7411. Epub 2017 Feb 1. Anatol J Cardiol. 2017. PMID: 28613211 Free PMC article.
When compared with non-treated controls, simvastatin significantly decreased cell viability (p=0.04) and cell count (p=0.03). ...These genes were involved in the regulation of apoptosis through various pathways. CONCLUSION: In summary, our study suggest that simvastatin …
When compared with non-treated controls, simvastatin significantly decreased cell viability (p=0.04) and cell count (p=0.03). ...Thes …
133 results