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2003 2
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2013 5
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No Association Between Ljungan Virus Seropositivity and the Beta-cell Damaging Process in the Finnish Type 1 Diabetes Prediction and Prevention Study Cohort.
Jääskeläinen AJ, Nurminen N, Kolehmainen P, Smura T, Tauriainen S, Toppari J, Ilonen J, Veijola R, Knip M, Hyöty H, Vapalahti O, Kallio-Kokko H. Jääskeläinen AJ, et al. Pediatr Infect Dis J. 2019 Mar;38(3):314-316. doi: 10.1097/INF.0000000000002201. Pediatr Infect Dis J. 2019. PMID: 30346370
BACKGROUND: Ljungan virus (LV) has not confirmed to associate with any human disease, but a possible connection with type 1 diabetes has been suggested. ...METHODS: We analyzed LV IgG seroprevalence in 102 case children (65 had also developed …
BACKGROUND: Ljungan virus (LV) has not confirmed to associate with any human disease, but a possible connection with type
A link between Ljungan virus and type 1 diabetes?
Woodland DL. Woodland DL. Viral Immunol. 2013 Jun;26(3):171. doi: 10.1089/vim.2013.ed.26.3. Viral Immunol. 2013. PMID: 23772973 No abstract available.
Serological evaluation of possible exposure to Ljungan virus and related parechovirus in autoimmune (type 1) diabetes in children.
Nilsson AL, Vaziri-Sani F, Broberg P, Elfaitouri A, Pipkorn R, Blomberg J, Ivarsson SA, Elding Larsson H, Lernmark Å. Nilsson AL, et al. J Med Virol. 2015 Jul;87(7):1130-40. doi: 10.1002/jmv.24127. Epub 2015 Apr 14. J Med Virol. 2015. PMID: 25873230
Exposure to Ljungan virus (LV) is implicated in the risk of autoimmune (type 1) diabetes but possible contribution by other parechoviruses is not ruled out. ...Both exploratory suspension multiplex IgG to LV-peptide VP1_31-60 and RBA detected LV …
Exposure to Ljungan virus (LV) is implicated in the risk of autoimmune (type 1) diabetes but possible con …
Development of type 1 diabetes in wild bank voles associated with islet autoantibodies and the novel ljungan virus.
Niklasson B, Heller KE, Schønecker B, Bildsøe M, Daniels T, Hampe CS, Widlund P, Simonson WT, Schaefer JB, Rutledge E, Bekris L, Lindberg AM, Johansson S, Ortqvist E, Persson B, Lernmark A. Niklasson B, et al. Int J Exp Diabesity Res. 2003 Jan-Mar;4(1):35-44. doi: 10.1080/15438600303733. Int J Exp Diabesity Res. 2003. PMID: 12745669 Free PMC article.

Levels of Ljungan virus antibodies were also increased in young age at onset of newly diagnosed type 1 diabetes in children (P < .01). These findings support the hypothesis that the development of type 1 diabetes in captu

Levels of Ljungan virus antibodies were also increased in young age at onset of newly diagnosed type 1 diabet
No Ljungan virus RNA in stool samples from the Norwegian environmental triggers of type 1 diabetes (MIDIA) cohort study.
Tapia G, Cinek O, Rasmussen T, Grinde B, Rønningen KS. Tapia G, et al. Diabetes Care. 2010 May;33(5):1069-71. doi: 10.2337/dc09-1951. Epub 2010 Feb 25. Diabetes Care. 2010. PMID: 20185738 Free PMC article.
OBJECTIVE: Ljungan virus (LjV) has been proposed as a potential environmental factor for type 1 diabetes. The objective was to test for any association of LjV with type 1 diabetes. ...LjV does not seem to be involved in the …
OBJECTIVE: Ljungan virus (LjV) has been proposed as a potential environmental factor for type 1 diabetes. …
Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats.
Holmberg R, Klitz W, Blixt M, Berggren PO, Juntti-Berggren L, Niklasson B. Holmberg R, et al. Microbiol Immunol. 2009 Oct;53(10):567-72. doi: 10.1111/j.1348-0421.2009.00160.x. Microbiol Immunol. 2009. PMID: 19780970 Free article.
The effects of LV in two different species, CD-1 mice, without a genetic disposition for diabetes, and BB rats prone to T1D were examined. Male CD-1 mice that had been exposed to LV in utero developed a type 2-like diabetes with increased blood …
The effects of LV in two different species, CD-1 mice, without a genetic disposition for diabetes, and BB rats prone to T1D we …
Characterization of beta-cell function of pancreatic islets isolated from bank voles developing glucose intolerance/diabetes: an animal model showing features of both type 1 and type 2 diabetes mellitus, and a possible role of the Ljungan virus.
Blixt M, Niklasson B, Sandler S. Blixt M, et al. Gen Comp Endocrinol. 2007 Oct-Dec;154(1-3):41-7. doi: 10.1016/j.ygcen.2007.06.019. Epub 2007 Jul 4. Gen Comp Endocrinol. 2007. PMID: 17686482
Bank voles (Clethrionomys glareolus) kept in captivity develop diabetes mellitus to a significant extent. Also in wild bank voles, elevated blood glucose has been observed. A newly isolated picornavirus named Ljungan virus (LV) has been found in the pa …
Bank voles (Clethrionomys glareolus) kept in captivity develop diabetes mellitus to a significant extent. Also in wild bank vo …
Relationship between Ljungan virus antibodies, HLA-DQ8, and insulin autoantibodies in newly diagnosed type 1 diabetes children.
Nilsson AL, Vaziri-Sani F, Andersson C, Larsson K, Carlsson A, Cedervall E, Jönsson B, Neiderud J, Elding Larsson H, Ivarsson SA, Lernmark Å. Nilsson AL, et al. Viral Immunol. 2013 Jun;26(3):207-15. doi: 10.1089/vim.2013.0008. Epub 2013 May 17. Viral Immunol. 2013. PMID: 23682738 Free PMC article.
Environmental factors, including viral infections, may explain an increasing and fluctuating incidence of childhood type 1 diabetes (T1D). Ljungan virus (LV) isolated from bank voles have been implicated, but it is unclear whether LV contributes …
Environmental factors, including viral infections, may explain an increasing and fluctuating incidence of childhood type 1
Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children.
Zhao G, Vatanen T, Droit L, Park A, Kostic AD, Poon TW, Vlamakis H, Siljander H, Härkönen T, Hämäläinen AM, Peet A, Tillmann V, Ilonen J, Wang D, Knip M, Xavier RJ, Virgin HW. Zhao G, et al. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6166-E6175. doi: 10.1073/pnas.1706359114. Epub 2017 Jul 10. Proc Natl Acad Sci U S A. 2017. PMID: 28696303 Free PMC article.
Here we defined the intestinal virome from birth to the development of autoimmunity in children at risk for type 1 diabetes (T1D). ...Enterovirus, kobuvirus, parechovirus, parvovirus, and rotavirus sequences were frequently detected but were not associ …
Here we defined the intestinal virome from birth to the development of autoimmunity in children at risk for type 1 diabetes
Ljungan virus is endemic in rodents in the UK.
Salisbury AM, Begon M, Dove W, Niklasson B, Stewart JP. Salisbury AM, et al. Arch Virol. 2014 Mar;159(3):547-51. doi: 10.1007/s00705-013-1731-6. Epub 2013 May 12. Arch Virol. 2014. PMID: 23665770
Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. LjV has been associated with [corrected] type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and
Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. LjV ha
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