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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 2
1978 3
1979 6
1980 3
1981 1
1982 6
1983 8
1984 5
1985 13
1986 5
1987 7
1988 6
1989 4
1991 5
1992 5
1993 3
1994 5
1995 5
1996 6
1997 5
1998 12
1999 4
2000 8
2001 7
2002 12
2003 12
2004 10
2005 10
2006 6
2007 9
2008 6
2009 5
2010 3
2011 3
2012 8
2013 9
2014 12
2015 10
2016 7
2017 7
2018 11
2019 4
2020 2
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263 results
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Page 1
Developing a vaccine for type 1 diabetes by targeting coxsackievirus B.
Hyöty H, Leon F, Knip M. Hyöty H, et al. Expert Rev Vaccines. 2018 Dec;17(12):1071-1083. doi: 10.1080/14760584.2018.1548281. Epub 2018 Nov 29. Expert Rev Vaccines. 2018. PMID: 30449209 Review.
INTRODUCTION: Virus infections have long been considered as a possible cause of type 1 diabetes (T1D). One virus group, enteroviruses (EVs), has been studied extensively, and clinical development of a vaccine against T1D-associated EV types has started. ...Pr …
INTRODUCTION: Virus infections have long been considered as a possible cause of type 1 diabetes (T1D). One virus group, …
A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes.
Stone VM, Hankaniemi MM, Svedin E, Sioofy-Khojine A, Oikarinen S, Hyöty H, Laitinen OH, Hytönen VP, Flodström-Tullberg M. Stone VM, et al. Diabetologia. 2018 Feb;61(2):476-481. doi: 10.1007/s00125-017-4492-z. Epub 2017 Nov 18. Diabetologia. 2018. PMID: 29151123 Free PMC article.
AIMS/HYPOTHESIS: Epidemiological studies suggest a role for Coxsackievirus B (CVB) serotypes in the pathogenesis of type 1 diabetes, but their actual contribution remains elusive. ...CONCLUSIONS/INTERPRETATION: CVB1 vaccine can efficiently protect agai …
AIMS/HYPOTHESIS: Epidemiological studies suggest a role for Coxsackievirus B (CVB) serotypes in the pathogenesis of type 1
Fulminant type 1 diabetes mellitus associated with Coxsackievirus type B1 infection during pregnancy: a case report.
Hayakawa T, Nakano Y, Hayakawa K, Yoshimatu H, Hori Y, Yamanishi K, Yamanishi H, Ota T, Fujimoto T. Hayakawa T, et al. J Med Case Rep. 2019 Jun 19;13(1):186. doi: 10.1186/s13256-019-2130-8. J Med Case Rep. 2019. PMID: 31215492 Free PMC article.
However, the association between fulminant type 1 diabetes in pregnancy and specific viral infections has not been reported. ...The patient in this case had fulminant type 1 diabetes in pregnancy associated with Coxsackievirus B1. CONCLUS …
However, the association between fulminant type 1 diabetes in pregnancy and specific viral infections has not been repo …
The Coincidence of Newly Diagnosed Type 1 Diabetes Mellitus with IgM Antibody Positivity to Enteroviruses and Respiratory Tract Viruses.
Karaoglan M, Eksi F. Karaoglan M, et al. J Diabetes Res. 2018 Aug 16;2018:8475341. doi: 10.1155/2018/8475341. eCollection 2018. J Diabetes Res. 2018. PMID: 30186878 Free PMC article.
OBJECTIVE: Viruses trigger and promote islet cell destruction and cause type 1 diabetes mellitus (T1DM). However, the existence of a cause-and-effect relationship is under debate. ...RESULTS: The percentages of viral IgM antibodies against most common …
OBJECTIVE: Viruses trigger and promote islet cell destruction and cause type 1 diabetes mellitus (T1DM). However …
Enterovirus persistence as a mechanism in the pathogenesis of type 1 diabetes.
Alidjinou EK, Sané F, Engelmann I, Geenen V, Hober D. Alidjinou EK, et al. Discov Med. 2014 Nov;18(100):273-82. Discov Med. 2014. PMID: 25425468 Free article. Review.
The persistence is believed to play a major role in the pathogenesis of EV related chronic diseases such as type 1 diabetes (T1D). ...EVs and especially group B coxsackieviruses (CVB) have been the most incriminated as exogenous agents involved in the …
The persistence is believed to play a major role in the pathogenesis of EV related chronic diseases such as type 1 diabetes
Molecular epidemiology of enteroviruses in young children at increased risk of type 1 diabetes.
Sioofy-Khojine AB, Oikarinen S, Honkanen H, Huhtala H, Lehtonen JP, Briese T, Hyöty H; TEDDY Study Group. Sioofy-Khojine AB, et al. PLoS One. 2018 Sep 7;13(9):e0201959. doi: 10.1371/journal.pone.0201959. eCollection 2018. PLoS One. 2018. PMID: 30192755 Free PMC article.
All of the children carried type HLA-DQ2 or -DQ8 alleles associated with type 1 diabetes. PRINCIPAL FINDINGS: Altogether 201 children (67%) were found to be EV positive. ...Coxsackieviruses type A were the most frequently detected viruses in all …
All of the children carried type HLA-DQ2 or -DQ8 alleles associated with type 1 diabetes. PRINCIPAL FINDINGS: Al …
Decreased in vitro type 1 immune response against coxsackie virus B4 in children with type 1 diabetes.
Skarsvik S, Puranen J, Honkanen J, Roivainen M, Ilonen J, Holmberg H, Ludvigsson J, Vaarala O. Skarsvik S, et al. Diabetes. 2006 Apr;55(4):996-1003. doi: 10.2337/diabetes.55.04.06.db05-0630. Diabetes. 2006. PMID: 16567521 Free article.
We wanted to compare the characteristics of T-cell immune response to CVB4 in children with type 1 diabetes and healthy children with and without HLA risk-associated haplotypes (HLA-DR3-DQ2 or HLA-DR4-DQ8) for type 1 diabetes. ...Accordin …
We wanted to compare the characteristics of T-cell immune response to CVB4 in children with type 1 diabetes and healthy …
Type 1 diabetes islet associated antibodies in subjects infected by echovirus 16.
Cabrera-Rode E, Sarmiento L, Tiberti C, Molina G, Barrios J, Hernández D, Díaz-Horta O, Di Mario U. Cabrera-Rode E, et al. Diabetologia. 2003 Oct;46(10):1348-53. doi: 10.1007/s00125-003-1179-4. Epub 2003 Jul 29. Diabetologia. 2003. PMID: 12898016
AIMS/HYPOTHESIS: To determine whether the emergent infection by echovirus 16 that occurred in Cuba during the year 2000 was related to the presence of Type 1 diabetes associated autoantibodies. ...Our data show that the echovirus 16 infection mi …
AIMS/HYPOTHESIS: To determine whether the emergent infection by echovirus 16 that occurred in Cuba during the year 2000 was related t …
Echovirus 4 and type 1 diabetes mellitus.
Díaz-Horta O, Bello M, Cabrera-Rode E, Suárez J, Más P, García I, Abalos I, Jofra R, Molina G, Díaz-Díaz O, Dimario U. Díaz-Horta O, et al. Autoimmunity. 2001;34(4):275-81. doi: 10.3109/08916930109014696. Autoimmunity. 2001. PMID: 11905853
AIMS/HYPOTHESIS: To determine the association between exposure to enteroviruses and Type 1 diabetes. METHODS: We measured neutralizing antibodies to the following enteroviruses: Coxsackievirus CA9, CB1, CB2, CB3, CB4, CB5, CB6, and Echovirus E4, E6, E9 …
AIMS/HYPOTHESIS: To determine the association between exposure to enteroviruses and Type 1 diabetes. METHODS: We measur …
Monocytes of Patients with Type 1 Diabetes Harbour Enterovirus RNA.
Alidjinou EK, Chehadeh W, Weill J, Vantyghem MC, Stuckens C, Decoster A, Hober C, Hober D. Alidjinou EK, et al. Eur J Clin Invest. 2015 Sep;45(9):918-24. doi: 10.1111/eci.12485. Epub 2015 Aug 6. Eur J Clin Invest. 2015. PMID: 26108863
BACKGROUND: Intracellular enterovirus (EV) RNA was detected in blood of patients with type 1 diabetes (T1D). The presence of EV RNA in subsets of peripheral blood mononuclear cells (PBMCs) of patients, and the in vitro infection of these cells with an …
BACKGROUND: Intracellular enterovirus (EV) RNA was detected in blood of patients with type 1 diabetes (T1D). The …
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