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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1983 1
1985 2
1986 3
1988 4
1989 3
1990 3
1991 5
1992 4
1994 3
1995 6
1997 4
1998 1
1999 2
2000 1
2001 2
2002 4
2003 2
2004 2
2005 5
2006 3
2007 1
2008 1
2009 5
2010 5
2011 2
2012 5
2013 4
2014 3
2015 2
2016 5
2017 4
2018 3
2019 2
2020 3
2021 3
2022 2
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103 results
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Page 1
High-throughput and high-dimensional single-cell analysis of antigen-specific CD8+ T cells.
Ma KY, Schonnesen AA, He C, Xia AY, Sun E, Chen E, Sebastian KR, Guo YW, Balderas R, Kulkarni-Date M, Jiang N. Ma KY, et al. Nat Immunol. 2021 Dec;22(12):1590-1598. doi: 10.1038/s41590-021-01073-2. Epub 2021 Nov 22. Nat Immunol. 2021. PMID: 34811538 Free PMC article.
We also evaluate gene expression and phenotypic differences among antigen-specific CD8(+) T cells and characterize phenotype signatures of influenza- and Epstein-Barr virus-specific CD8(+) T cells that are unique to their pathogen targets. Moreover, with the high-th …
We also evaluate gene expression and phenotypic differences among antigen-specific CD8(+) T cells and characterize phenotype signatures of i …
Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity.
Harley JB, Chen X, Pujato M, Miller D, Maddox A, Forney C, Magnusen AF, Lynch A, Chetal K, Yukawa M, Barski A, Salomonis N, Kaufman KM, Kottyan LC, Weirauch MT. Harley JB, et al. Nat Genet. 2018 May;50(5):699-707. doi: 10.1038/s41588-018-0102-3. Epub 2018 Apr 16. Nat Genet. 2018. PMID: 29662164 Free PMC article.
Strikingly, nearly half of systemic lupus erythematosus risk loci are occupied by the Epstein-Barr virus EBNA2 protein and many coclustering human TFs, showing gene-environment interaction. Similar EBNA2-anchored associations exist in multiple sclerosis, rheumatoid …
Strikingly, nearly half of systemic lupus erythematosus risk loci are occupied by the Epstein-Barr virus EBNA2 protein and man …
Effects of Type 1 Diabetes Risk Alleles on Immune Cell Gene Expression.
Ram R, Morahan G. Ram R, et al. Genes (Basel). 2017 Jun 21;8(6):167. doi: 10.3390/genes8060167. Genes (Basel). 2017. PMID: 28635624 Free PMC article. Review.
Genetic studies have identified 61 variants associated with the risk of developing Type 1 Diabetes (T1D). The functions of most of the non-HLA (Human Leukocyte Antigen) genetic variants remain unknown. ...To do so, we examined whole transcriptome profiles of …
Genetic studies have identified 61 variants associated with the risk of developing Type 1 Diabetes (T1D). The functions …
Epstein-Barr and other herpesvirus infections in patients with early onset type 1 diabetes treated with daclizumab and mycophenolate mofetil.
Loechelt BJ, Boulware D, Green M, Baden LR, Gottlieb P, Krause-Steinrauf H, Weinberg A; Type 1 Diabetes TrialNet Daclizumab/Mycophenolic Acid Study Group. Loechelt BJ, et al. Clin Infect Dis. 2013 Jan;56(2):248-54. doi: 10.1093/cid/cis848. Epub 2012 Oct 5. Clin Infect Dis. 2013. PMID: 23042974 Free PMC article.
BACKGROUND: We assessed the morbidity of herpesviruses in patients with type 1 diabetes mellitus (T1D) enrolled in immunosuppressive treatment studies. ...There were no CMV reactivations. Of 30 baseline HSV-seropositive subjects, 8 developed 1 e …
BACKGROUND: We assessed the morbidity of herpesviruses in patients with type 1 diabetes mellitus (T1D) enrolled …
Fulminant type 1 diabetes mellitus associated with a reactivation of Epstein-Barr virus that developed in the course of chemotherapy of multiple myeloma.
Fujiya A, Ochiai H, Mizukoshi T, Kiyota A, Shibata T, Suzuki A, Ohashi N, Sobajima H. Fujiya A, et al. J Diabetes Investig. 2010 Dec 3;1(6):286-9. doi: 10.1111/j.2040-1124.2010.00061.x. J Diabetes Investig. 2010. PMID: 24843446 Free PMC article.
Three months after beginning chemotherapy, she was readmitted to the hospital because of fever and hepatopathy. Her elevated Epstein-Barr virus (EBV) antibody levels showed that the hepatopathy was caused by reactivation of EBV. ...The serum C-peptide level was belo …
Three months after beginning chemotherapy, she was readmitted to the hospital because of fever and hepatopathy. Her elevated Epstein- …
Relating homology between the Epstein-Barr virus BOLF1 molecule and HLA-DQw8 beta chain to recent onset type 1 (insulin-dependent) diabetes mellitus.
Sairenji T, Daibata M, Sorli CH, Qvistbäck H, Humphreys RE, Ludvigsson J, Palmer J, Landin-Olsson M, Sundkvist G, Michelsen B, et al. Sairenji T, et al. Diabetologia. 1991 Jan;34(1):33-9. doi: 10.1007/BF00404022. Diabetologia. 1991. PMID: 1647336
A role for the Epstein-Barr virus in initiating Type 1 (insulin-dependent) diabetes mellitus has been proposed since Epstein-Barr virus BOLF1 (497-513) AVTPL RIFIVPPAAEY has an 11 amino acid identity with HLA-DQw8 beta (49-6 …
A role for the Epstein-Barr virus in initiating Type 1 (insulin-dependent) diabetes mellitus has b …
A new look at viruses in type 1 diabetes.
Jun HS, Yoon JW. Jun HS, et al. Diabetes Metab Res Rev. 2003 Jan-Feb;19(1):8-31. doi: 10.1002/dmrr.337. Diabetes Metab Res Rev. 2003. PMID: 12592641 Review.
Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells. ...In addition, a review of transgenic animal models for virus-induced autoimmune diabetes is included, particularly with regard to lymphocytic choriomeningitis virus, influen …
Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells. ...In addition, a review of transgenic ani …
Pearls in autoimmunity.
de Carvalho JF, Pereira RM, Shoenfeld Y. de Carvalho JF, et al. Auto Immun Highlights. 2011 Mar 23;2(1):1-4. doi: 10.1007/s13317-011-0016-x. eCollection 2011 May. Auto Immun Highlights. 2011. PMID: 26000114 Free PMC article. Review.
This manuscript does a review of the more frequent issues published at Autoimmunity Reviews, Journal of Autoimmunity and Autoimmunity in the period of January-December 2009. The following topics were commented: (1) multiple sclerosis (MS) and its relationships with Epst …
This manuscript does a review of the more frequent issues published at Autoimmunity Reviews, Journal of Autoimmunity and Autoimmunity in the …
Normal suppressive T cell function of Epstein-Barr virus induced B cell activation in type 1 (insulin dependent) diabetes mellitus.
Kahan A, LeFloch JP, Charreire J. Kahan A, et al. Autoimmunity. 1990;5(4):257-64. doi: 10.3109/08916939009014710. Autoimmunity. 1990. PMID: 1966582
To investigate whether this abnormality is a common feature to other autoimmune diseases, we studied T cell regulation of Epstein-Barr virus induced B cell activation in 15 newly diagnosed type 1 (insulin dependent) diabetes mellitus pati …
To investigate whether this abnormality is a common feature to other autoimmune diseases, we studied T cell regulation of Epstein- …
A randomised, single-blind, placebo-controlled, dose-finding safety and tolerability study of the anti-CD3 monoclonal antibody otelixizumab in new-onset type 1 diabetes.
Keymeulen B, van Maurik A, Inman D, Oliveira J, McLaughlin R, Gittelman RM, Roep BO, Gillard P, Hilbrands R, Gorus F, Mathieu C, Van de Velde U, Wisniacki N, Napolitano A. Keymeulen B, et al. Diabetologia. 2021 Feb;64(2):313-324. doi: 10.1007/s00125-020-05317-y. Epub 2020 Nov 4. Diabetologia. 2021. PMID: 33145642 Free PMC article. Clinical Trial.
AIMS/HYPOTHESIS: Numerous clinical studies have investigated the anti-CD3e monoclonal antibody otelixizumab in individuals with type 1 diabetes, but limited progress has been made in identifying the optimal clinical dose with acceptable tolerability and safet …
AIMS/HYPOTHESIS: Numerous clinical studies have investigated the anti-CD3e monoclonal antibody otelixizumab in individuals with type …
103 results