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1983 1
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2003 1
2004 3
2005 7
2006 1
2007 2
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2009 3
2010 3
2011 2
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2013 5
2014 6
2015 2
2016 3
2017 3
2018 1
2020 1
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Page 1
Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children.
Zhao G, Vatanen T, Droit L, Park A, Kostic AD, Poon TW, Vlamakis H, Siljander H, Härkönen T, Hämäläinen AM, Peet A, Tillmann V, Ilonen J, Wang D, Knip M, Xavier RJ, Virgin HW. Zhao G, et al. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6166-E6175. doi: 10.1073/pnas.1706359114. Epub 2017 Jul 10. Proc Natl Acad Sci U S A. 2017. PMID: 28696303 Free PMC article.
Here we defined the intestinal virome from birth to the development of autoimmunity in children at risk for type 1 diabetes (T1D). ...Enterovirus, kobuvirus, parechovirus, parvovirus, and rotavirus sequences were frequently detected but were not associ …
Here we defined the intestinal virome from birth to the development of autoimmunity in children at risk for type 1 diabetes
Case of fulminant type 1 diabetes mellitus associated with parvovirus B19 infection.
Nishiumi T, Okamoto K, Inamoto S, Inoue N, Ohnishi K, Ohji G, Hirota Y, Ogawa W. Nishiumi T, et al. J Diabetes Investig. 2014 Jul;5(4):472-3. doi: 10.1111/jdi.12173. Epub 2014 Jul 18. J Diabetes Investig. 2014. PMID: 25411609 Free PMC article. No abstract available.
Involvement of adipose tissue inflammation and dysfunction in virus-induced type 1 diabetes.
Needell JC, Brown MN, Zipris D. Needell JC, et al. J Endocrinol. 2018 Jul;238(1):61-75. doi: 10.1530/JOE-18-0131. Epub 2018 May 9. J Endocrinol. 2018. PMID: 29743341
The etiopathogenesis of type 1 diabetes (T1D) remains poorly understood. We used the LEW1.WR1 rat model of Kilham rat virus (KRV)-induced T1D to better understand the role of the innate immune system in the mechanism of virus-induced disease. ...In sharp cont …
The etiopathogenesis of type 1 diabetes (T1D) remains poorly understood. We used the LEW1.WR1 rat model of Kilham rat v …
A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats.
Qaisar N, Lin S, Ryan G, Yang C, Oikemus SR, Brodsky MH, Bortell R, Mordes JP, Wang JP. Qaisar N, et al. Diabetes. 2017 Jan;66(1):145-157. doi: 10.2337/db16-0462. Epub 2016 Oct 7. Diabetes. 2017. PMID: 27999109 Free PMC article.
The pathogenesis of human type 1 diabetes, characterized by immune-mediated damage of insulin-producing β-cells of pancreatic islets, may involve viral infection. Essential components of the innate immune antiviral response, including type I interferon …
The pathogenesis of human type 1 diabetes, characterized by immune-mediated damage of insulin-producing β-cells of panc …
Viruses in type 1 diabetes: brief review.
Yoon JW, Jun HS. Yoon JW, et al. ILAR J. 2004;45(3):343-8. doi: 10.1093/ilar.45.3.343. ILAR J. 2004. PMID: 15229381 Review.
Type 1 diabetes results from the progressive destruction of insulin-producing pancreatic beta cells. Although the etiology of type 1 diabetes is believed to have a major genetic component, studies on the risk of developing type
Type 1 diabetes results from the progressive destruction of insulin-producing pancreatic beta cells. Although the etiol
Salicylate prevents virus-induced type 1 diabetes in the BBDR rat.
Yang C, Jurczyk A, diIorio P, Norowski E, Brehm MA, Grant CW, Guberski DL, Greiner DL, Bortell R. Yang C, et al. PLoS One. 2013 Oct 16;8(10):e78050. doi: 10.1371/journal.pone.0078050. eCollection 2013. PLoS One. 2013. PMID: 24147110 Free PMC article.
Epidemiologic and clinical evidence suggests that virus infection plays an important role in human type 1 diabetes pathogenesis. ...Salicylate prevented diabetes in a dose-dependent manner, and diabetes-free animals had no evidence of insulitis. …
Epidemiologic and clinical evidence suggests that virus infection plays an important role in human type 1 diabetes path …
The role of parvovirus B19 in the pathogenesis of autoimmunity and autoimmune disease.
Kerr JR. Kerr JR. J Clin Pathol. 2016 Apr;69(4):279-91. doi: 10.1136/jclinpath-2015-203455. Epub 2015 Dec 7. J Clin Pathol. 2016. PMID: 26644521 Review.
Production of a variety of autoantibodies has been demonstrated to occur during B19 infection and these have been shown to be key to the pathogenesis of the particular disease process in a significant number of cases, for example, production of rheumatoid factor in cases of B19-a …
Production of a variety of autoantibodies has been demonstrated to occur during B19 infection and these have been shown to be key to the pat …
Innate immunity in type 1 diabetes.
Zipris D. Zipris D. Diabetes Metab Res Rev. 2011 Nov;27(8):824-9. doi: 10.1002/dmrr.1256. Diabetes Metab Res Rev. 2011. PMID: 22069267
BACKGROUND: Rat models of diabetes have emerged as a powerful experimental tool for addressing the role of microbial pathogens in the mechanism of autoimmune diabetes. We have used the biobreeding diabetes resistant and LEW1.WR1 rat models to identify the rol …
BACKGROUND: Rat models of diabetes have emerged as a powerful experimental tool for addressing the role of microbial pathogens in the …
Viruses cause type 1 diabetes in animals.
Yoon JW, Jun HS. Yoon JW, et al. Ann N Y Acad Sci. 2006 Oct;1079:138-46. doi: 10.1196/annals.1375.021. Ann N Y Acad Sci. 2006. PMID: 17130545 Review.
More than 10 viruses have been reported to be associated with the development of type 1 diabetes-like symptoms in animals, with the best evidence coming from studies on the D variant of encephalomyocarditis (EMC-D) virus in mice and Kilham rat virus (KRV) in …
More than 10 viruses have been reported to be associated with the development of type 1 diabetes-like symptoms in anima …
Modulation of virus-induced innate immunity and type 1 diabetes by IL-1 blockade.
Hara N, Alkanani AK, Dinarello CA, Zipris D. Hara N, et al. Innate Immun. 2014 Aug;20(6):574-84. doi: 10.1177/1753425913502242. Epub 2013 Sep 23. Innate Immun. 2014. PMID: 24062197 Free article.
We used the LEW1.WR1 model of Kilham rat virus (KRV)-induced type 1 diabetes (T1D) to test the hypothesis that blocking IL-1 pathways early in the course of the disease can modulate virus-induced innate immunity and prevent disease progression. ...Fina …
We used the LEW1.WR1 model of Kilham rat virus (KRV)-induced type 1 diabetes (T1D) to test the hypothesis that blocking …
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