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1983 1
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1996 2
1997 1
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2003 1
2004 3
2005 7
2006 1
2007 2
2008 1
2009 3
2010 3
2011 2
2012 1
2013 5
2014 6
2015 2
2016 3
2017 3
2018 1
2020 1
2021 2
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Page 1
Rat Models of Virus-Induced Type 1 Diabetes.
Needell JC, Zipris D. Needell JC, et al. Methods Mol Biol. 2020;2128:107-114. doi: 10.1007/978-1-0716-0385-7_8. Methods Mol Biol. 2020. PMID: 32180189
Studies performed in humans and animal models have implicated the environment in the etiology of type 1 diabetes (T1D), but the nature and timing of the interactions triggering beta cell autoimmunity are poorly understood. ...The immunophenotype of these stra …
Studies performed in humans and animal models have implicated the environment in the etiology of type 1 diabetes (T1D), …
Type I IFN-Driven Immune Cell Dysregulation in Rat Autoimmune Diabetes.
Qaisar N, Arowosegbe A, Derr AG, Kucukural A, Satish B, Racicot R, Guo Z, Trombly MI, Wang JP. Qaisar N, et al. Immunohorizons. 2021 Oct 26;5(10):855-869. doi: 10.4049/immunohorizons.2100088. Immunohorizons. 2021. PMID: 34702762 Free PMC article.
Type 1 diabetes is a chronic autoimmune disease, characterized by the immune-mediated destruction of insulin-producing beta cells of pancreatic islets. Essential components of the innate immune antiviral response, including type I IFN and IFN receptor
Type 1 diabetes is a chronic autoimmune disease, characterized by the immune-mediated destruction of insulin-producing
Visceral Adipose Tissue: A New Target Organ in Virus-Induced Type 1 Diabetes.
Zipris D. Zipris D. Front Immunol. 2021 Aug 4;12:702506. doi: 10.3389/fimmu.2021.702506. eCollection 2021. Front Immunol. 2021. PMID: 34421908 Free PMC article. Review.
Type 1 diabetes (T1D) is a proinflammatory pathology that leads to the specific destruction of insulin producing beta-cells and hyperglycaemia. Much of the knowledge about type 1 diabetes (T1D) has focused on mechanisms of disease progres
Type 1 diabetes (T1D) is a proinflammatory pathology that leads to the specific destruction of insulin producing beta-c
Viruses in type 1 diabetes: brief review.
Yoon JW, Jun HS. Yoon JW, et al. ILAR J. 2004;45(3):343-8. doi: 10.1093/ilar.45.3.343. ILAR J. 2004. PMID: 15229381 Review.
Type 1 diabetes results from the progressive destruction of insulin-producing pancreatic beta cells. Although the etiology of type 1 diabetes is believed to have a major genetic component, studies on the risk of developing type
Type 1 diabetes results from the progressive destruction of insulin-producing pancreatic beta cells. Although the etiol
Viruses cause type 1 diabetes in animals.
Yoon JW, Jun HS. Yoon JW, et al. Ann N Y Acad Sci. 2006 Oct;1079:138-46. doi: 10.1196/annals.1375.021. Ann N Y Acad Sci. 2006. PMID: 17130545 Review.
More than 10 viruses have been reported to be associated with the development of type 1 diabetes-like symptoms in animals, with the best evidence coming from studies on the D variant of encephalomyocarditis (EMC-D) virus in mice and Kilham rat virus (KRV) in …
More than 10 viruses have been reported to be associated with the development of type 1 diabetes-like symptoms in anima …
Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms.
Zipris D. Zipris D. Clin Immunol. 2009 Apr;131(1):11-23. doi: 10.1016/j.clim.2008.12.011. Epub 2009 Jan 29. Clin Immunol. 2009. PMID: 19185542 Review.
There is a consensus among epidemiologists that the worldwide incidence rate of type 1 diabetes has been rising in recent decades. The cause of this rise is unknown, but epidemiological studies suggest the involvement of environmental factors, and viral infec …
There is a consensus among epidemiologists that the worldwide incidence rate of type 1 diabetes has been rising in rece …
Salicylate prevents virus-induced type 1 diabetes in the BBDR rat.
Yang C, Jurczyk A, diIorio P, Norowski E, Brehm MA, Grant CW, Guberski DL, Greiner DL, Bortell R. Yang C, et al. PLoS One. 2013 Oct 16;8(10):e78050. doi: 10.1371/journal.pone.0078050. eCollection 2013. PLoS One. 2013. PMID: 24147110 Free PMC article.
Epidemiologic and clinical evidence suggests that virus infection plays an important role in human type 1 diabetes pathogenesis. We used the virus-inducible BioBreeding Diabetes Resistant (BBDR) rat to investigate the ability of sodium salicylate, a no …
Epidemiologic and clinical evidence suggests that virus infection plays an important role in human type 1 diabetes path …
Innate immunity in type 1 diabetes.
Zipris D. Zipris D. Diabetes Metab Res Rev. 2011 Nov;27(8):824-9. doi: 10.1002/dmrr.1256. Diabetes Metab Res Rev. 2011. PMID: 22069267
BACKGROUND: Rat models of diabetes have emerged as a powerful experimental tool for addressing the role of microbial pathogens in the mechanism of autoimmune diabetes. We have used the biobreeding diabetes resistant and LEW1.WR1 rat models to identify the rol …
BACKGROUND: Rat models of diabetes have emerged as a powerful experimental tool for addressing the role of microbial pathogens in the …
Viral infections as potential triggers of type 1 diabetes.
van der Werf N, Kroese FG, Rozing J, Hillebrands JL. van der Werf N, et al. Diabetes Metab Res Rev. 2007 Mar;23(3):169-83. doi: 10.1002/dmrr.695. Diabetes Metab Res Rev. 2007. PMID: 17103489 Review.
During the last decades, the incidence of type 1 diabetes (T1D) has increased significantly, reaching percentages of 3% annually worldwide. ...Future studies will hopefully reveal which human viruses are causally involved in the induction of T1D and this know …
During the last decades, the incidence of type 1 diabetes (T1D) has increased significantly, reaching percentages of 3% …
51 results