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Immunisation and type 1 diabetes mellitus: is there a link?
Hiltunen M, Lönnrot M, Hyöty H. Hiltunen M, et al. Drug Saf. 1999 Mar;20(3):207-12. doi: 10.2165/00002018-199920030-00001. Drug Saf. 1999. PMID: 10221850 Review.
Recent evidence from animal studies has raised the possibility that immunisation by vaccines can influence the pathogenesis of type I (insulin-dependent) diabetes mellitus. In non-obese diabetic mice and biobreeding rats, complete Freund's adjuvant and bacill …
Recent evidence from animal studies has raised the possibility that immunisation by vaccines can influence the pathogenesis of type I …
HLA-DQ-conferred risk for type 1 diabetes does not alter neutralizing antibody response to a widely used enterovirus vaccine, the poliovirus vaccine.
Sioofy-Khojine AB, Lehtonen JP, Nurminen N, Laiho JE, Toppari J, Veijola R, Lempainen J, Ilonen J, Knip M, Hyöty H. Sioofy-Khojine AB, et al. J Med Virol. 2023 Mar 27. doi: 10.1002/jmv.28707. Online ahead of print. J Med Virol. 2023. PMID: 36971180
Neutralizing antibodies induced by - inactivated poliovirus vaccine against poliovirus type 1 (Salk) were analysed as a marker of protective immunity at the age of 18 months in a prospective birth cohort. No differences were observed in antibody titers …
Neutralizing antibodies induced by - inactivated poliovirus vaccine against poliovirus type 1 (Salk) were analys …
Childhood vaccination and type 1 diabetes.
Hviid A, Stellfeld M, Wohlfahrt J, Melbye M. Hviid A, et al. N Engl J Med. 2004 Apr 1;350(14):1398-404. doi: 10.1056/NEJMoa032665. N Engl J Med. 2004. PMID: 15070789 Free article.
RESULTS: Type 1 diabetes was diagnosed in 681 children during 4,720,517 person-years of follow-up. ...The development of type 1 diabetes in genetically predisposed children (defined as those who had siblings with type 1 d …
RESULTS: Type 1 diabetes was diagnosed in 681 children during 4,720,517 person-years of follow-up. ...The development o …
[Immunity to poliovirus after vaccination of children with type 1 diabetes mellitus and rheumatic diseases].
Tarasova AA, Kniagina ON, Kalashnikova NA, Kostinov MP, Erukhimov VL. Tarasova AA, et al. Zh Mikrobiol Epidemiol Immunobiol. 2009 Sep-Oct;(5):52-6. Zh Mikrobiol Epidemiol Immunobiol. 2009. PMID: 20063794 Russian.
AIM: To assess immunization coverage against poliomyelitis and level of immunity postvaccination in children with type 1 diabetes mellitus (DM1) and rheumatic diseases. MATERIALS AND METHODS: Vaccination status of 299 children with DM1 and 136 children …
AIM: To assess immunization coverage against poliomyelitis and level of immunity postvaccination in children with type 1 di …
Live attenuated enterovirus vaccine (OPV) is not associated with islet autoimmunity in children with genetic susceptibility to type 1 diabetes: prospective cohort study.
Viskari H, Oikarinen S, Hoppu S, Vuorinen T, Huhtala H, Toppari J, Veijola R, Ilonen J, Knip M, Hyöty H. Viskari H, et al. Diabetologia. 2018 Jan;61(1):203-209. doi: 10.1007/s00125-017-4410-4. Epub 2017 Sep 2. Diabetologia. 2018. PMID: 28866779
AIMS/HYPOTHESIS: Animal and human studies have implied that enterovirus infections may modulate the risk of islet autoimmunity and type 1 diabetes. We set out to assess whether serial administration of live oral poliovirus vaccine (OPV) in early life c …
AIMS/HYPOTHESIS: Animal and human studies have implied that enterovirus infections may modulate the risk of islet autoimmunity and type …
Coxsackievirus B4 as a Causative Agent of Diabetes Mellitus Type 1: Is There a Role of Inefficiently Treated Drinking Water and Sewage in Virus Spreading?
El-Senousy WM, Abdel-Moneim A, Abdel-Latif M, El-Hefnawy MH, Khalil RG. El-Senousy WM, et al. Food Environ Virol. 2018 Mar;10(1):89-98. doi: 10.1007/s12560-017-9322-4. Epub 2017 Oct 11. Food Environ Virol. 2018. PMID: 29022248
This study proposed to detect the enterovirus (EV) infection in children with type 1 diabetes mellitus (T1D) and to assess the role of insufficiently treated water and sewage as sources of viral spreading. ...Characterization of the EV amplicons by RT- …
This study proposed to detect the enterovirus (EV) infection in children with type 1 diabetes mellitus (T1D) and …
Salivary anti-coxsackievirus-B4 neutralizing activity and pattern of immune parameters in patients with type 1 diabetes: a pilot study.
Nekoua MP, Yessoufou A, Alidjinou EK, Badia-Boungou F, Moutairou K, Sane F, Hober D. Nekoua MP, et al. Acta Diabetol. 2018 Aug;55(8):827-834. doi: 10.1007/s00592-018-1158-3. Epub 2018 May 17. Acta Diabetol. 2018. PMID: 29774468
AIMS: Enteroviruses, especially coxsackieviruses B (CV-B), have been associated with the pathogenesis of type 1 diabetes (T1D). An anti-CV-B4 neutralizing activity in saliva of T1D patients was previously reported. ...METHODS: Saliva and blood samples were co …
AIMS: Enteroviruses, especially coxsackieviruses B (CV-B), have been associated with the pathogenesis of type 1 diabetes …
Serological evaluation of possible exposure to Ljungan virus and related parechovirus in autoimmune (type 1) diabetes in children.
Nilsson AL, Vaziri-Sani F, Broberg P, Elfaitouri A, Pipkorn R, Blomberg J, Ivarsson SA, Elding Larsson H, Lernmark Å. Nilsson AL, et al. J Med Virol. 2015 Jul;87(7):1130-40. doi: 10.1002/jmv.24127. Epub 2015 Apr 14. J Med Virol. 2015. PMID: 25873230
Exposure to Ljungan virus (LV) is implicated in the risk of autoimmune (type 1) diabetes but possible contribution by other parechoviruses is not ruled out. The aim was to compare children diagnosed with type 1 diabetes in 2005-2011 (n = …
Exposure to Ljungan virus (LV) is implicated in the risk of autoimmune (type 1) diabetes but possible contribution by o …
Induction of interferon-gamma and IL-4 production by mitogen and specific antigens in peripheral blood lymphocytes of Type 1 diabetes patients.
Halminen M, Juhela S, Vaarala O, Simell O, Ilonen J. Halminen M, et al. Autoimmunity. 2001;34(1):1-8. doi: 10.3109/08916930108994120. Autoimmunity. 2001. PMID: 11681488
A functional imbalance in cytokine production resulting in dominance of Th1 over Th2 type response has been suggested to play a critical role in the pathogenesis of type 1 diabetes. ...Two enterovirus preparates were included due to the suggested signi …
A functional imbalance in cytokine production resulting in dominance of Th1 over Th2 type response has been suggested to play a criti …
Variation in enterovirus receptor genes.
Karttunen A, Pöyry T, Vaarala O, Ilonen J, Hovi T, Roivainen M, Hyypiä T. Karttunen A, et al. J Med Virol. 2003 May;70(1):99-108. doi: 10.1002/jmv.10352. J Med Virol. 2003. PMID: 12629650
The increased incidence of a enterovirus infections observed in patients with type 1 diabetes preceding the development of the clinical disease could be partially explained by variation in the genes coding for enterovirus receptors. ...In conclusion, both syn …
The increased incidence of a enterovirus infections observed in patients with type 1 diabetes preceding the development …
33 results