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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
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3,180 results

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Page 1
Undenatured type II collagen and its role in improving osteoarthritis.
Xu R, Wu J, Zheng L, Zhao M. Xu R, et al. Ageing Res Rev. 2023 Nov;91:102080. doi: 10.1016/j.arr.2023.102080. Epub 2023 Sep 27. Ageing Res Rev. 2023. PMID: 37774932 Review.
Type II collagen has been extensively explored for its potential in improving arthritis. Methods of extraction of type II collagen are inefficient and tedious. The method of limited enzymatic hydrolysis is mainly used to prepare soluble u …
Type II collagen has been extensively explored for its potential in improving arthritis. Methods of extraction of ty …
Undenatured type II collagen for knee osteoarthritis.
Gupta A, Maffulli N. Gupta A, et al. Ann Med. 2025 Dec;57(1):2493306. doi: 10.1080/07853890.2025.2493306. Epub 2025 Apr 20. Ann Med. 2025. PMID: 40253594 Free PMC article. Review.
INTRODUCTION: Knee Osteoarthritis (OA) leads to significant pain and reduced function and affects patients' overall quality of life (QoL). ...The use of nutraceuticals, including native/undenatured type II collagen (UC-2), has evolved and shown promise …
INTRODUCTION: Knee Osteoarthritis (OA) leads to significant pain and reduced function and affects patients' overall quality of life ( …
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study.
Lugo JP, Saiyed ZM, Lane NE. Lugo JP, et al. Nutr J. 2016 Jan 29;15:14. doi: 10.1186/s12937-016-0130-8. Nutr J. 2016. PMID: 26822714 Free PMC article. Clinical Trial.
BACKGROUND: Undenatured type II collagen (UC-II) is a nutritional supplement derived from chicken sternum cartilage. The purpose of this study was to evaluate the efficacy and tolerability of UC-II for knee osteoarthritis (OA) pain and as …
BACKGROUND: Undenatured type II collagen (UC-II) is a nutritional supplement derived from chicken sternum cartil …
Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial.
Crowley DC, Lau FC, Sharma P, Evans M, Guthrie N, Bagchi M, Bagchi D, Dey DK, Raychaudhuri SP. Crowley DC, et al. Int J Med Sci. 2009 Oct 9;6(6):312-21. doi: 10.7150/ijms.6.312. Int J Med Sci. 2009. PMID: 19847319 Free PMC article. Clinical Trial.
Previous studies have shown that undenatured type II collagen (UC-II) is effective in the treatment of rheumatoid arthritis, and preliminary human and animal trials have shown it to be effective in treating osteoarthritis (OA). ...Specifically, …
Previous studies have shown that undenatured type II collagen (UC-II) is effective in the treatment of rheumatoi …
Efficacy of combined undenatured type II collagen and hydrolysed collagen supplementation in knee osteoarthritis: a randomised controlled trial.
Yuenyongviwat V, Anusitviwat C, Tuntarattanapong P, Hongnaparak T, Iamthanaporn K. Yuenyongviwat V, et al. Sci Rep. 2025 Sep 2;15(1):32313. doi: 10.1038/s41598-025-17505-0. Sci Rep. 2025. PMID: 40897777 Free PMC article. Clinical Trial.
This study aimed to evaluate the efficacy of combined undenatured type II collagen (UC-II) and hydrolysed collagen supplementation in patients with knee osteoarthritis. In this randomised, double-blind, placebo-controlled trial, 68 patien …
This study aimed to evaluate the efficacy of combined undenatured type II collagen (UC-II) and hydrolysed col …
Type II collagen markers in osteoarthritis: what do they indicate?
Henrotin Y, Addison S, Kraus V, Deberg M. Henrotin Y, et al. Curr Opin Rheumatol. 2007 Sep;19(5):444-50. doi: 10.1097/BOR.0b013e32829fb3b5. Curr Opin Rheumatol. 2007. PMID: 17762609 Review.
Based on this analysis, we propose an update to the classification of the type II collagen biomarkers. RECENT FINDINGS: Various type II collagen epitopes have been described as potential biomarkers for osteoarthritis. ...SUMMARY: …
Based on this analysis, we propose an update to the classification of the type II collagen biomarkers. RECENT FINDINGS: …
C-Terminal Cross-Linked Telopeptides of Type II Collagen as Biomarker for Radiological Knee Osteoarthritis: A Meta-Analysis.
Cheng H, Hao B, Sun J, Yin M. Cheng H, et al. Cartilage. 2020 Oct;11(4):512-520. doi: 10.1177/1947603518798884. Epub 2018 Sep 15. Cartilage. 2020. PMID: 30221987 Free PMC article. Review.
BACKGROUND: C-terminal cross-linked telopeptides of type II collagen (CTX-II) are one of the most frequently assessed markers for osteoarthritis (OA) diagnosis. The aim of this meta-analysis was to confirm the diagnostic value of urinary CTX- …
BACKGROUND: C-terminal cross-linked telopeptides of type II collagen (CTX-II) are one of the most frequently ass …
[Undenatured type II collagen in the treatment of osteoarthritis].
Sütő G. Sütő G. Orv Hetil. 2021 Sep 12;162(37):1481-1484. doi: 10.1556/650.2021.32337. Orv Hetil. 2021. PMID: 34516398 Hungarian.
Orv Hetil. 2021; 162(37): 1481-1484. Summary. Osteoarthritis is a disease of the cartilage, bone and surrounding soft tissues that make up the joints. ...Immunological inflammatory processes also play a role in its development, the influence of which allows not only sympto …
Orv Hetil. 2021; 162(37): 1481-1484. Summary. Osteoarthritis is a disease of the cartilage, bone and surrounding soft tissues that ma …
Blood and urine biomarkers in osteoarthritis - an update on cartilage associated type II collagen and aggrecan markers.
Bay-Jensen AC, Mobasheri A, Thudium CS, Kraus VB, Karsdal MA. Bay-Jensen AC, et al. Curr Opin Rheumatol. 2022 Jan 1;34(1):54-60. doi: 10.1097/BOR.0000000000000845. Curr Opin Rheumatol. 2022. PMID: 34652292 Free PMC article. Review.
In this narrative review, we provide highlights on biomarkers derived from the two most studied and abundant cartilage proteins - type II collagen and aggrecan. RECENT FINDINGS: Multiple biomarkers assessing type II collagen degradation a …
In this narrative review, we provide highlights on biomarkers derived from the two most studied and abundant cartilage proteins - type …
Ferrous/Ferric Ions Crosslinked Type II Collagen Multifunctional Hydrogel for Advanced Osteoarthritis Treatment.
Wang L, Chen X, Wang S, Ma J, Yang X, Chen H, Xiao J. Wang L, et al. Adv Healthc Mater. 2024 Apr;13(10):e2302833. doi: 10.1002/adhm.202302833. Epub 2024 Jan 7. Adv Healthc Mater. 2024. PMID: 38185787
Herein, a novel discovery wherein the simple incorporation of ferrous/ferric ions enables efficient dynamic crosslinking of type II collagen, leading to the development of injectable, self-healing hydrogels with 3D interconnected porous nanostructures, is unv …
Herein, a novel discovery wherein the simple incorporation of ferrous/ferric ions enables efficient dynamic crosslinking of type I …
3,180 results