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2006 2
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2010 5
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2018 3
2019 3
2020 12
2021 2
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41 results
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SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres.
Vančevska A, Ahmed W, Pfeiffer V, Feretzaki M, Boulton SJ, Lingner J. Vančevska A, et al. EMBO J. 2020 Apr 1;39(7):e102668. doi: 10.15252/embj.2019102668. Epub 2020 Feb 21. EMBO J. 2020. PMID: 32080884 Free PMC article.
Together, these data indicate that SMCHD1 depletion reduces telomere fusions in TRF2-depleted cells due to defects in ATM-dependent checkpoint signaling and that SMCHD1 mediates DNA damage response activation upstream of ATM phosphorylation at uncapped telomeres....
Together, these data indicate that SMCHD1 depletion reduces telomere fusions in TRF2-depleted cells due to defects in ATM-dependent checkpoi …
Full-length 5'RACE identifies all major HBV transcripts in HBV-infected hepatocytes and patient serum.
Stadelmayer B, Diederichs A, Chapus F, Rivoire M, Neveu G, Alam A, Fraisse L, Carter K, Testoni B, Zoulim F. Stadelmayer B, et al. J Hepatol. 2020 Jul;73(1):40-51. doi: 10.1016/j.jhep.2020.01.028. Epub 2020 Feb 20. J Hepatol. 2020. PMID: 32087349
We found pgRNA, 1 spliced pgRNA variant and a variety of HBx transcripts associated with viral particles generated by HepAD38 cells. The different HBx RNAs are both capped and uncapped. Lastly, we identified 3 major categories of circulating RNA species in patients with ch …
We found pgRNA, 1 spliced pgRNA variant and a variety of HBx transcripts associated with viral particles generated by HepAD38 cells. The dif …
Human RAP1 specifically protects telomeres of senescent cells from DNA damage.
Lototska L, Yue JX, Li J, Giraud-Panis MJ, Songyang Z, Royle NJ, Liti G, Ye J, Gilson E, Mendez-Bermudez A. Lototska L, et al. EMBO Rep. 2020 Apr 3;21(4):e49076. doi: 10.15252/embr.201949076. Epub 2020 Feb 25. EMBO Rep. 2020. PMID: 32096305 Free PMC article.
Downregulation of RAP1 in these cells, but not in young or dividing pre-senescent cells, leads to telomere uncapping and fusions. The anti-fusion effect of RAP1 was further explored in a HeLa cell line where RAP1 expression was depleted through an inducible CRISPR/Cas9 str …
Downregulation of RAP1 in these cells, but not in young or dividing pre-senescent cells, leads to telomere uncapping and fusions. The …
Revisiting the Self-Assembly of Highly Aromatic Phenylalanine Homopeptides.
Mayans E, Alemán C. Mayans E, et al. Molecules. 2020 Dec 20;25(24):6037. doi: 10.3390/molecules25246037. Molecules. 2020. PMID: 33419355 Free PMC article. Review.
Special attention has been paid to the influence of solvent: co-solvent mixture used to solubilize the peptide, the peptide concentration and, in some cases, the temperature. More specifically, uncapped (FF, FFF, and FFFF), N-capped with Fmoc (Fmoc-FF, Fmoc-FFF, and Fmoc-F …
Special attention has been paid to the influence of solvent: co-solvent mixture used to solubilize the peptide, the peptide concentration an …
Laser Printing of Plasmonic Nanosponges.
Syubaev S, Gurbatov S, Modin E, Linklater DP, Juodkazis S, Gurevich EL, Kuchmizhak A. Syubaev S, et al. Nanomaterials (Basel). 2020 Dec 4;10(12):2427. doi: 10.3390/nano10122427. Nanomaterials (Basel). 2020. PMID: 33291684 Free PMC article.
Most of the nanopores hidden beneath the nanobump surface can be further uncapped using gentle etching of the nanobumps by an Ar-ion beam to form functional 3D plasmonic nanosponges. ...
Most of the nanopores hidden beneath the nanobump surface can be further uncapped using gentle etching of the nanobumps by an Ar-ion …
Effect of bioturbation on contaminated sediment deposited over remediated sediment.
Knox AS, Paller MH. Knox AS, et al. Sci Total Environ. 2020 Apr 15;713:136537. doi: 10.1016/j.scitotenv.2020.136537. Epub 2020 Jan 9. Sci Total Environ. 2020. PMID: 31955083
We deposited sediment contaminated with As, Cd, Cu, Ni, Pb, and Zn over clean sediment capped with the sequestering agent, apatite, and clean uncapped sediment in laboratory mesocosms to simulate the recontamination of remediated sediment by influxes of particle-bound cont …
We deposited sediment contaminated with As, Cd, Cu, Ni, Pb, and Zn over clean sediment capped with the sequestering agent, apatite, and clea …
Study of Oxidation and Polarization-Dependent Optical Properties of Environmentally Stable Layered GaTe Using a Novel Passivation Approach.
Kotha M, Murray T, Tuschel D, Gallis S. Kotha M, et al. Nanomaterials (Basel). 2019 Oct 23;9(11):1510. doi: 10.3390/nano9111510. Nanomaterials (Basel). 2019. PMID: 31652827 Free PMC article.
A combination of correlation and comparison of Raman and PL studies reveal that the HSQ-capped GaTe flakes are effectively protected from oxidation in air ambient over the studied-period of one year, and thus, preserving their structural and optical characteristics. This contrast …
A combination of correlation and comparison of Raman and PL studies reveal that the HSQ-capped GaTe flakes are effectively protected from ox …
Synthesis of Functional Silver Nanoparticles and Microparticles with Modifiers and Evaluation of Their Antimicrobial, Anticancer, and Antioxidant Activity.
Dilshad E, Bibi M, Sheikh NA, Tamrin KF, Mansoor Q, Maqbool Q, Nawaz M. Dilshad E, et al. J Funct Biomater. 2020 Oct 23;11(4):76. doi: 10.3390/jfb11040076. J Funct Biomater. 2020. PMID: 33113975 Free PMC article.
SEM analysis revealed a round plate-like morphology of maleic acid capped particles with an average size of 39 4 nm, whereas citric acid capped particles display flower-shaped morphology with rough surfaces and an average size of 250 5 nm. The uncapped AgMPs were hexagonal …
SEM analysis revealed a round plate-like morphology of maleic acid capped particles with an average size of 39 4 nm, whereas citric acid cap …
Controlled Lengthwise Assembly of Helical Peptide Nanofibers to Modulate CD8+ T-Cell Responses.
Fries CN, Wu Y, Kelly SH, Wolf M, Votaw NL, Zauscher S, Collier JH. Fries CN, et al. Adv Mater. 2020 Oct;32(39):e2003310. doi: 10.1002/adma.202003310. Epub 2020 Aug 20. Adv Mater. 2020. PMID: 32820582
Demonstrating their use as immunotherapies, capped nanofibers are preferentially cross-presented by dendritic cells compared to uncapped nanofibers. Due to increased cross-presentation, these capped nanofibers trigger stronger CD8(+) T-cell responses in mice than uncapp
Demonstrating their use as immunotherapies, capped nanofibers are preferentially cross-presented by dendritic cells compared to uncapped
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