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Current Aspects of the Endocannabinoid System and Targeted THC and CBD Phytocannabinoids as Potential Therapeutics for Parkinson's and Alzheimer's Diseases: a Review.
Cooray R, Gupta V, Suphioglu C. Cooray R, et al. Mol Neurobiol. 2020 Nov;57(11):4878-4890. doi: 10.1007/s12035-020-02054-6. Epub 2020 Aug 19. Mol Neurobiol. 2020. PMID: 32813239 Free PMC article. Review.
The delta-9-tetrahydrocannabinoid (delta(9)-THC) and cannabidiol (CBD) cannabinoids of plant Cannabis sativa have shown neuroprotection upon PD and AD animal models yet triggered toxic effects on patients when administered directly. Therefore, understanding the precise …
The delta-9-tetrahydrocannabinoid (delta(9)-THC) and cannabidiol (CBD) cannabinoids of plant Cannabis sativa have shown neuroprotection upon …
Understanding the molecular aspects of tetrahydrocannabinol and cannabidiol as antioxidants.
Borges RS, Batista J Jr, Viana RB, Baetas AC, Orestes E, Andrade MA, Honório KM, da Silva AB. Borges RS, et al. Molecules. 2013 Oct 14;18(10):12663-74. doi: 10.3390/molecules181012663. Molecules. 2013. PMID: 24129275 Free PMC article.
An antioxidant mechanism of tetrahydrocannabinol (THC) and cannabidiol (CBD) were compared with a simplified model of alpha-tocopherol, butylhydroxytoluene and hydroxytoluene in order to understand the antioxidant nature of THC and CBD molecules using DFT. ...
An antioxidant mechanism of tetrahydrocannabinol (THC) and cannabidiol (CBD) were compared with a simplified model of alpha-tocophero …
Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history.
Bonini SA, Premoli M, Tambaro S, Kumar A, Maccarinelli G, Memo M, Mastinu A. Bonini SA, et al. J Ethnopharmacol. 2018 Dec 5;227:300-315. doi: 10.1016/j.jep.2018.09.004. Epub 2018 Sep 8. J Ethnopharmacol. 2018. PMID: 30205181 Review.
The key psychoactive constituent in C. sativa is called delta-9-tetrahydrocannabinol (D9-THC). The endocannabinoid system seems to be phylogenetically ancient, as it was present in the most primitive vertebrates with a neuronal network. ...AIM OF THE STUDY: The review aims …
The key psychoactive constituent in C. sativa is called delta-9-tetrahydrocannabinol (D9-THC). The endocannabinoid system seems to be …
Medicinal Applications of Cannabinoids Extracted from Cannabis sativa (L.): A New Route in the Fight Against COVID-19?
Khalid S, Almalki FA, Hadda TB, Bader A, Abu-Izneid T, Berredjem M, Elsharkawy ER, Alqahtani AM. Khalid S, et al. Curr Pharm Des. 2021;27(13):1564-1578. doi: 10.2174/1381612826666201202125807. Curr Pharm Des. 2021. PMID: 33267756 Review.
C. sativa contains several hundred phytoconstituents, including the infamous "cannabinoids". It is necessary to properly understand the medicinal importance of these phytochemicals and spread awareness among the countries where cannabis is still facing legal obstacles. The …
C. sativa contains several hundred phytoconstituents, including the infamous "cannabinoids". It is necessary to properly understand t …
Pharmacological properties, therapeutic potential, and legal status of Cannabis sativa L.: An overview.
Kumar P, Mahato DK, Kamle M, Borah R, Sharma B, Pandhi S, Tripathi V, Yadav HS, Devi S, Patil U, Xiao J, Mishra AK. Kumar P, et al. Phytother Res. 2021 Nov;35(11):6010-6029. doi: 10.1002/ptr.7213. Epub 2021 Jul 8. Phytother Res. 2021. PMID: 34237796 Review.
The existence of major compounds including delta(9) -tetrahydrocannabinol (delta(9) -THC), cannabidiol, cannabinol, and cannabichromene contributes to the medicinal effects of the cannabis plant. ...Cannabis sativa is a plant with significant pharmacological potential. How …
The existence of major compounds including delta(9) -tetrahydrocannabinol (delta(9) -THC), cannabidiol, cannabinol, and cannabichrome …