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Year Number of Results
1972 1
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1988 5
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2000 5
2001 10
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976 results

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Page 1
Candida auris Genetics and Emergence.
Chowdhary A, Jain K, Chauhan N. Chowdhary A, et al. Annu Rev Microbiol. 2023 Sep 15;77:583-602. doi: 10.1146/annurev-micro-032521-015858. Epub 2023 Jul 5. Annu Rev Microbiol. 2023. PMID: 37406342 Free article. Review.
Since the first reported case in 2009 in Japan, C. auris infections have been reported in more than 40 countries, with mortality rates between 30% and 60%. ...Most importantly, C. auris is the first fungal pathogen to show pronounced and sometimes untreatable clinic …
Since the first reported case in 2009 in Japan, C. auris infections have been reported in more than 40 countries, with mortality rate …
Antibiotic resistance.
Frieri M, Kumar K, Boutin A. Frieri M, et al. J Infect Public Health. 2017 Jul-Aug;10(4):369-378. doi: 10.1016/j.jiph.2016.08.007. Epub 2016 Sep 6. J Infect Public Health. 2017. PMID: 27616769 Free article. Review.
Multidrug resistance patterns in Gram-positive and -negative bacteria are difficult to treat and may even be untreatable with conventional antibiotics. There is currently a shortage of effective therapies, lack of successful prevention measures, and only a few new antibiot …
Multidrug resistance patterns in Gram-positive and -negative bacteria are difficult to treat and may even be untreatable with convent …
CAR T therapy beyond cancer: the evolution of a living drug.
Baker DJ, Arany Z, Baur JA, Epstein JA, June CH. Baker DJ, et al. Nature. 2023 Jul;619(7971):707-715. doi: 10.1038/s41586-023-06243-w. Epub 2023 Jul 26. Nature. 2023. PMID: 37495877 Review.
Engineering a patient's own T cells to selectively target and eliminate tumour cells has cured patients with untreatable haematologic cancers. These results have energized the field to apply chimaeric antigen receptor (CAR) T therapy throughout oncology. However, evidence …
Engineering a patient's own T cells to selectively target and eliminate tumour cells has cured patients with untreatable haematologic …
Trying to treat the untreatable: experimental approaches to clear rabies virus infection from the CNS.
Smith SP, Wu G, Fooks AR, Ma J, Banyard AC. Smith SP, et al. J Gen Virol. 2019 Aug;100(8):1171-1186. doi: 10.1099/jgv.0.001269. Epub 2019 Jun 25. J Gen Virol. 2019. PMID: 31237530 Review.
Despite the availability of safe and effective vaccines, the clinical stages of rabies encephalitis remain untreatable, with few survivors being documented. A principal obstacle to the treatment of rabies is the neurotropic nature of the virus, with the blood-brain barrier …
Despite the availability of safe and effective vaccines, the clinical stages of rabies encephalitis remain untreatable, with few surv …
Mycoplasma genitalium: A Review.
Gnanadurai R, Fifer H. Gnanadurai R, et al. Microbiology (Reading). 2020 Jan;166(1):21-29. doi: 10.1099/mic.0.000830. Microbiology (Reading). 2020. PMID: 31329090 Free article. Review.
First isolated in 1981, much is still unknown regarding its natural history in untreated infection. It is recognized as a sexually transmitted pathogen causing acute and chronic non-gonococcal urethritis (NGU) in men, with a growing body of evidence to suggest it also caus …
First isolated in 1981, much is still unknown regarding its natural history in untreated infection. It is recognized as a sexually tr …
Multidrug efflux pumps: structure, function and regulation.
Du D, Wang-Kan X, Neuberger A, van Veen HW, Pos KM, Piddock LJV, Luisi BF. Du D, et al. Nat Rev Microbiol. 2018 Sep;16(9):523-539. doi: 10.1038/s41579-018-0048-6. Nat Rev Microbiol. 2018. PMID: 30002505 Review.
Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly throughout the world and threaten to become untreatable. ...Clinical and laboratory data indicate that efflux pumps function not only in the drug extrusion process but also in viru
Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly throughout the world and threaten to become
Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae.
Ernst CM, Braxton JR, Rodriguez-Osorio CA, Zagieboylo AP, Li L, Pironti A, Manson AL, Nair AV, Benson M, Cummins K, Clatworthy AE, Earl AM, Cosimi LA, Hung DT. Ernst CM, et al. Nat Med. 2020 May;26(5):705-711. doi: 10.1038/s41591-020-0825-4. Epub 2020 Apr 13. Nat Med. 2020. PMID: 32284589 Free PMC article.
We demonstrate that K. pneumoniae can enhance its pathogenicity by adopting two opposing infection programs through easily acquired gain- and loss-of-function mutations. ...In the latter case, drug-tolerant K. pneumoniae can persist to yield potentially untreatab
We demonstrate that K. pneumoniae can enhance its pathogenicity by adopting two opposing infection programs through easily acq …
New guidelines for hospital-acquired pneumonia/ventilator-associated pneumonia: USA vs. Europe.
Martin-Loeches I, Rodriguez AH, Torres A. Martin-Loeches I, et al. Curr Opin Crit Care. 2018 Oct;24(5):347-352. doi: 10.1097/MCC.0000000000000535. Curr Opin Crit Care. 2018. PMID: 30063491 Review.
There is an implicit risk, when appropriate means broad spectrum, that liberal use of antimicrobial combinations will encourage the emergence of multidrug resistant (MDR), extensively drug-resistant (XDR) and pandrug-resistant bacteria (PDR) and generate untreatable inf
There is an implicit risk, when appropriate means broad spectrum, that liberal use of antimicrobial combinations will encourage the emergenc …
The prospect of untreatable gonorrhoea.
Johnson AP, Hughes G. Johnson AP, et al. BMJ. 2017 Aug 25;358:j3973. doi: 10.1136/bmj.j3973. BMJ. 2017. PMID: 28842528 No abstract available.
976 results