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1998 5
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215 results

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Page 1
Internal senses of the vagus nerve.
Prescott SL, Liberles SD. Prescott SL, et al. Neuron. 2022 Feb 16;110(4):579-599. doi: 10.1016/j.neuron.2021.12.020. Epub 2022 Jan 19. Neuron. 2022. PMID: 35051375 Free PMC article. Review.
The vagus nerve is an indispensable body-brain connection that controls vital aspects of autonomic physiology like breathing, heart rate, blood pressure, and gut motility, reflexes like coughing and swallowing, and survival behaviors like feeding, drin …
The vagus nerve is an indispensable body-brain connection that controls vital aspects of autonomic physiology like breathing, …
Neurotransmitter modulation by the gut microbiota.
Strandwitz P. Strandwitz P. Brain Res. 2018 Aug 15;1693(Pt B):128-133. doi: 10.1016/j.brainres.2018.03.015. Brain Res. 2018. PMID: 29903615 Free PMC article. Review.
By leveraging animal models, several different pathways of communication have been identified along the "gut-brain-axis" including those driven by the immune system, the vagus nerve, or by modulation of neuroactive compounds by the microbiota. ...In this revi …
By leveraging animal models, several different pathways of communication have been identified along the "gut-brain-axis" including th …
Noninvasive electrical neuromodulation for gastrointestinal motility disorders.
Yin J, Chen JD. Yin J, et al. Expert Rev Gastroenterol Hepatol. 2023 Dec;17(12):1221-1232. doi: 10.1080/17474124.2023.2288156. Epub 2024 Jan 17. Expert Rev Gastroenterol Hepatol. 2023. PMID: 38018087 Free PMC article. Review.
INTRODUCTION: Gastrointestinal motility disorders are highly prevalent without satisfactory treatment. noninvasive electrical neuromodulation is an emerging therapy for treating various gastrointestinal motility disorders. AREAS COVERED: In this review, several emer …
INTRODUCTION: Gastrointestinal motility disorders are highly prevalent without satisfactory treatment. noninvasive electrical neuromo …
Ameliorating effects of transcutaneous auricular vagus nerve stimulation on a mouse model of constipation-predominant irritable bowel syndrome.
Liu J, Dai Q, Qu T, Ma J, Lv C, Wang H, Yu Y. Liu J, et al. Neurobiol Dis. 2024 Apr;193:106440. doi: 10.1016/j.nbd.2024.106440. Epub 2024 Feb 16. Neurobiol Dis. 2024. PMID: 38369213 Free article.
We investigated the effects of transcutaneous auricular vagus nerve stimulation (taVNS) in a mouse model of IBS-C. In the current study, C57BL/6 mice were randomly divided into normal control, IBS-C model control, sham-electrostimulation (sham-ES), taVNS, and drug t …
We investigated the effects of transcutaneous auricular vagus nerve stimulation (taVNS) in a mouse model of IBS-C. In the curr …
Sensory Neurons that Detect Stretch and Nutrients in the Digestive System.
Williams EK, Chang RB, Strochlic DE, Umans BD, Lowell BB, Liberles SD. Williams EK, et al. Cell. 2016 Jun 30;166(1):209-21. doi: 10.1016/j.cell.2016.05.011. Epub 2016 May 26. Cell. 2016. PMID: 27238020 Free PMC article.
Neural inputs from internal organs are essential for normal autonomic function. The vagus nerve is a key body-brain connection that monitors the digestive, cardiovascular, and respiratory systems. ...These studies clarify the roles of vagal afferents in mediating pa …
Neural inputs from internal organs are essential for normal autonomic function. The vagus nerve is a key body-brain connection …
A brainstem map for visceral sensations.
Ran C, Boettcher JC, Kaye JA, Gallori CE, Liberles SD. Ran C, et al. Nature. 2022 Sep;609(7926):320-326. doi: 10.1038/s41586-022-05139-5. Epub 2022 Aug 31. Nature. 2022. PMID: 36045291 Free PMC article.
For example, the olfactory system uses large receptor repertoires and is wired to recognize diverse odours, whereas the visual system provides high acuity of object position, form and movement(1-5). Compared to external sensory systems, principles that underlie sensory pro …
For example, the olfactory system uses large receptor repertoires and is wired to recognize diverse odours, whereas the visual system provid …
Transcutaneous auricular vagus nerve stimulation influences gastric motility: A randomized, double-blind trial in healthy individuals.
Steidel K, Krause K, Menzler K, Strzelczyk A, Immisch I, Fuest S, Gorny I, Mross P, Hakel L, Schmidt L, Timmermann L, Rosenow F, Bauer S, Knake S. Steidel K, et al. Brain Stimul. 2021 Sep-Oct;14(5):1126-1132. doi: 10.1016/j.brs.2021.06.006. Epub 2021 Jun 27. Brain Stimul. 2021. PMID: 34187756 Free article. Clinical Trial.
BACKGROUND: Transcutaneous auricular vagus nerve stimulation (taVNS) has been investigated regarding its therapeutic properties in several several conditions such as epilepsy, migraine and major depressive disorder and was shown to access similar neural pathways as …
BACKGROUND: Transcutaneous auricular vagus nerve stimulation (taVNS) has been investigated regarding its therapeutic propertie …
Electroconvulsive therapy improves distal colonic motility via the subdiaphragmatic vagus nerve in depressive-like mice.
Dai M, Li Y, Tian Y. Dai M, et al. Sci Rep. 2025 Jun 4;15(1):19597. doi: 10.1038/s41598-025-04114-0. Sci Rep. 2025. PMID: 40467736 Free PMC article.
Complementary experiments in mice revealed that daily ECS not only reversed depressive-like behaviors but also restored colonic motility. This effect was closely associated with the normalization of neural activity in the hypothalamic paraventricular nucleus (PVN), a key b …
Complementary experiments in mice revealed that daily ECS not only reversed depressive-like behaviors but also restored colonic motility …
Migraine and Gastroparesis.
Arca KN, Cai J, Wang F, Kassim G, Hasler WL, Batheja MJ. Arca KN, et al. Curr Neurol Neurosci Rep. 2022 Dec;22(12):813-821. doi: 10.1007/s11910-022-01241-3. Epub 2022 Nov 12. Curr Neurol Neurosci Rep. 2022. PMID: 36370318 Review.
Gastric dysmotility in the setting of migraine can impact absorption of oral migraine medications and alternate formulations should be considered for some patients. Noninvasive vagus nerve stimulation has been FDA cleared for migraine treatment and is also being stu …
Gastric dysmotility in the setting of migraine can impact absorption of oral migraine medications and alternate formulations should be consi …
The gut-brain axis in early Parkinson's disease: from prodrome to prevention.
Oliver PJ, Civitelli L, Hu MT. Oliver PJ, et al. J Neurol. 2025 May 21;272(6):413. doi: 10.1007/s00415-025-13138-5. J Neurol. 2025. PMID: 40394204 Free PMC article. Review.
It is unclear what triggers Parkinson's and where alpha-synuclein protein aggregation begins, although proposed induction sites include the olfactory bulb and dorsal motor nucleus of the vagus nerve. Within the last 20 years, there has been increasing evidence that …
It is unclear what triggers Parkinson's and where alpha-synuclein protein aggregation begins, although proposed induction sites include the …
215 results