Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1980 1
1982 1
1985 1
1997 1
2000 1
2002 3
2003 2
2004 1
2005 4
2006 1
2007 2
2008 4
2009 4
2010 3
2011 5
2012 4
2013 7
2014 7
2015 7
2016 10
2017 7
2018 16
2019 16
2020 16
2021 22
2022 23
2023 29
2024 42
2025 56

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

263 results

Results by year

Filters applied: . Clear all
Page 1
Transcutaneous Auricular Vagus Nerve Stimulation (ta-VNS) for Treatment of Drug-Resistant Epilepsy: A Randomized, Double-Blind Clinical Trial.
Yang H, Shi W, Fan J, Wang X, Song Y, Lian Y, Shan W, Wang Q. Yang H, et al. Neurotherapeutics. 2023 Apr;20(3):870-880. doi: 10.1007/s13311-023-01353-9. Epub 2023 Mar 30. Neurotherapeutics. 2023. PMID: 36995682 Free PMC article. Clinical Trial.
This study explored the efficacy and safety of transcutaneous auricular vagus nerve stimulation (ta-VNS) in patients with epilepsy. A total of 150 patients were randomly divided into active stimulation group and control group. At baseline and 4, 12, an …
This study explored the efficacy and safety of transcutaneous auricular vagus nerve stimulation (ta-VNS) in patients wi …
Transcutaneous auricular vagus nerve stimulation ameliorates adolescent depressive- and anxiety-like behaviors via hippocampus glycolysis and inflammation response.
Sun L, Ma S, Yu Y, Li X, Wei Q, Min L, Rong P. Sun L, et al. CNS Neurosci Ther. 2024 Feb;30(2):e14614. doi: 10.1111/cns.14614. CNS Neurosci Ther. 2024. PMID: 38358062 Free PMC article.
BACKGROUND: Transcutaneous auricular vagus nerve stimulation (taVNS) is a crucial neuromodulation therapy for depression, yet its molecular mechanism remains unclear. ...TaVNS could significantly ameliorate depressive- and anxiety-like behaviors. Its e …
BACKGROUND: Transcutaneous auricular vagus nerve stimulation (taVNS) is a crucial neuromodulation therapy for depressio …
Ultrasound stimulation of the vagus nerve as a treatment modality for anxiety.
Goyal M, Goyal R, Sanguinetti JL. Goyal M, et al. Front Psychiatry. 2024 Oct 2;15:1376140. doi: 10.3389/fpsyt.2024.1376140. eCollection 2024. Front Psychiatry. 2024. PMID: 39415887 Free PMC article. Review.
To remedy this, non-invasive ultrasound stimulation to the vagus nerve is a novel, low-cost treatment that is showing promise. Although vagus nerve stimulation is already approved for epilepsy and other conditions, it requires regular mai …
To remedy this, non-invasive ultrasound stimulation to the vagus nerve is a novel, low-cost treatment that is showing p …
Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatric and Inflammatory Disorders.
Breit S, Kupferberg A, Rogler G, Hasler G. Breit S, et al. Front Psychiatry. 2018 Mar 13;9:44. doi: 10.3389/fpsyt.2018.00044. eCollection 2018. Front Psychiatry. 2018. PMID: 29593576 Free PMC article. Review.
There is preliminary evidence that vagus nerve stimulation is a promising add-on treatment for treatment-refractory depression, posttraumatic stress disorder, and inflammatory bowel disease. Treatments that target the vagus nerve increase the va …
There is preliminary evidence that vagus nerve stimulation is a promising add-on treatment for treatment-refractory dep …
Critical Review of Transcutaneous Vagus Nerve Stimulation: Challenges for Translation to Clinical Practice.
Yap JYY, Keatch C, Lambert E, Woods W, Stoddart PR, Kameneva T. Yap JYY, et al. Front Neurosci. 2020 Apr 28;14:284. doi: 10.3389/fnins.2020.00284. eCollection 2020. Front Neurosci. 2020. PMID: 32410932 Free PMC article. Review.
Several studies have illustrated that transcutaneous vagus nerve stimulation (tVNS) can elicit therapeutic effects that are similar to those produced by its invasive counterpart, vagus nerve stimulation (VNS). ...In contrast, tVNS is a no …
Several studies have illustrated that transcutaneous vagus nerve stimulation (tVNS) can elicit therapeutic effects that …
Vagus nerve stimulation and gut microbiota interactions: A novel therapeutic avenue for neuropsychiatric disorders.
Faraji N, Payami B, Ebadpour N, Gorji A. Faraji N, et al. Neurosci Biobehav Rev. 2025 Feb;169:105990. doi: 10.1016/j.neubiorev.2024.105990. Epub 2024 Dec 21. Neurosci Biobehav Rev. 2025. PMID: 39716559 Free article. Review.
The gut microbiota (GM) plays a pivotal role in the progression of these diseases, influencing the brain and mental health through the gut-brain axis (GBA). The vagus nerve plays a significant role in the GBA, making it a key area of focus for potential novel therap …
The gut microbiota (GM) plays a pivotal role in the progression of these diseases, influencing the brain and mental health through the gut-b …
Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression.
Guo B, Zhang M, Hao W, Wang Y, Zhang T, Liu C. Guo B, et al. Transl Psychiatry. 2023 Jan 9;13(1):5. doi: 10.1038/s41398-022-02297-y. Transl Psychiatry. 2023. PMID: 36624089 Free PMC article. Review.
This review summarizes clinical and animal studies on inflammation in neural circuits related to anxiety and depression and the evidence that neuromodulation therapies regulate neuroinflammation in the treatment of neurological diseases. Neuromodulation therapies, includin …
This review summarizes clinical and animal studies on inflammation in neural circuits related to anxiety and depression and the evide …
Vagus nerve stimulation in treatment-resistant depression: A one-year, randomized, sham-controlled trial.
Conway CR, Aaronson ST, Sackeim HA, George MS, Zajecka J, Bunker MT, Duffy W, Stedman M, Riva-Posse P, Allen RM, Quevedo J, Berger M, Alva G, Malik MA, Dunner DL, Cichowicz I, Banov M, Manu L, Nahas Z, Macaluso M, Mickey BJ, Sheline Y, Kriedt CL, Lee YL, Gordon C, Shy O, Tran Q, Yates L, Rush AJ. Conway CR, et al. Brain Stimul. 2025 May-Jun;18(3):676-689. doi: 10.1016/j.brs.2024.12.1191. Epub 2024 Dec 18. Brain Stimul. 2025. PMID: 39706521 Free article. Clinical Trial.
OBJECTIVE: Evaluate the safety and effectiveness of FDA-approved adjunctive vagus nerve stimulation (VNS) in patients with marked TRD. METHODS: This 12-month, multicenter, double-blind, sham-controlled trial included 493 adults with marked treatment-resistant …
OBJECTIVE: Evaluate the safety and effectiveness of FDA-approved adjunctive vagus nerve stimulation (VNS) in patients w …
Transcutaneous auricular vagus nerve stimulators: a review of past, present, and future devices.
Wang L, Wang Y, Wang Y, Wang F, Zhang J, Li S, Wu M, Li L, Rong P. Wang L, et al. Expert Rev Med Devices. 2022 Jan;19(1):43-61. doi: 10.1080/17434440.2022.2020095. Epub 2022 Jan 13. Expert Rev Med Devices. 2022. PMID: 34937487 Review.
INTRODUCTION: As an emerging neuromodulation therapy, transcutaneous auricular vagus nerve stimulation (taVNS) has been proven to be safe and effective for epilepsy, major depressive disorders, insomnia, glucose metabolic disorders, pain, stroke, post stroke …
INTRODUCTION: As an emerging neuromodulation therapy, transcutaneous auricular vagus nerve stimulation (taVNS) has been …
Learnings from 30 years of reported efficacy and safety of vagus nerve stimulation (VNS) for epilepsy treatment: A critical review.
Toffa DH, Touma L, El Meskine T, Bouthillier A, Nguyen DK. Toffa DH, et al. Seizure. 2020 Dec;83:104-123. doi: 10.1016/j.seizure.2020.09.027. Epub 2020 Oct 10. Seizure. 2020. PMID: 33120323 Free article. Review.
Three decades after its introduction as an adjuvant therapeutic option in the management of selective drug-resistant epilepsy cases (DRE), vagus nerve stimulation (VNS) retains growing interest. An implantable device was first approved for epilepsy in Europe …
Three decades after its introduction as an adjuvant therapeutic option in the management of selective drug-resistant epilepsy cases (DRE), …
263 results