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108 results

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Page 1
Vagus Nerve Stimulation and the Cardiovascular System.
Capilupi MJ, Kerath SM, Becker LB. Capilupi MJ, et al. Cold Spring Harb Perspect Med. 2020 Feb 3;10(2):a034173. doi: 10.1101/cshperspect.a034173. Cold Spring Harb Perspect Med. 2020. PMID: 31109966 Free PMC article. Review.
The vagus nerve plays an important role in maintaining physiological homeostasis, which includes reflex pathways that regulate cardiac function. ...Recently, vagus nerve stimulation (VNS) has been investigated as a therapeutic for a multitude of …
The vagus nerve plays an important role in maintaining physiological homeostasis, which includes reflex pathways that regulate …
Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis.
Koopman FA, Chavan SS, Miljko S, Grazio S, Sokolovic S, Schuurman PR, Mehta AD, Levine YA, Faltys M, Zitnik R, Tracey KJ, Tak PP. Koopman FA, et al. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8284-9. doi: 10.1073/pnas.1605635113. Epub 2016 Jul 5. Proc Natl Acad Sci U S A. 2016. PMID: 27382171 Free PMC article. Clinical Trial.
Vagus nerve stimulation (up to four times daily) in RA patients significantly inhibited TNF production for up to 84 d. Moreover, RA disease severity, as measured by standardized clinical composite scores, improved significantly. Together, these results establ …
Vagus nerve stimulation (up to four times daily) in RA patients significantly inhibited TNF production for up to 84 d. …
Vagus nerve stimulation in musculoskeletal diseases.
Courties A, Berenbaum F, Sellam J. Courties A, et al. Joint Bone Spine. 2021 May;88(3):105149. doi: 10.1016/j.jbspin.2021.105149. Epub 2021 Feb 3. Joint Bone Spine. 2021. PMID: 33548494 Free article. Clinical Trial.
The vagus nerve is the main nerve of the parasympathetic autonomic nervous system. Beyond its vegetative functions, the vagus nerve possesses anti-inflammatory and analgesic properties. Initially developed in the treatment of refractory epilepsy …
The vagus nerve is the main nerve of the parasympathetic autonomic nervous system. Beyond its vegetative functions, the …
Anti-inflammatory properties of the vagus nerve: potential therapeutic implications of vagus nerve stimulation.
Bonaz B, Sinniger V, Pellissier S. Bonaz B, et al. J Physiol. 2016 Oct 15;594(20):5781-5790. doi: 10.1113/JP271539. Epub 2016 May 1. J Physiol. 2016. PMID: 27059884 Free PMC article. Review.
Brain and viscera interplay within the autonomic nervous system where the vagus nerve (VN), containing approximately 80% afferent and 20% efferent fibres, plays multiple key roles in the homeostatic regulations of visceral functions. ...The last pathway is the splen …
Brain and viscera interplay within the autonomic nervous system where the vagus nerve (VN), containing approximately 80% affer …
Vagus nerve stimulation in rheumatoid arthritis.
Staats PS, Poree L. Staats PS, et al. Lancet Rheumatol. 2021 Jan;3(1):e14. doi: 10.1016/S2665-9913(20)30360-X. Lancet Rheumatol. 2021. PMID: 38273634 No abstract available.
Vagus nerve stimulation: a new bioelectronics approach to treat rheumatoid arthritis?
Koopman FA, Schuurman PR, Vervoordeldonk MJ, Tak PP. Koopman FA, et al. Best Pract Res Clin Rheumatol. 2014 Aug;28(4):625-35. doi: 10.1016/j.berh.2014.10.015. Epub 2014 Nov 20. Best Pract Res Clin Rheumatol. 2014. PMID: 25481554 Free article. Review.
This led us to study the effects of alpha7nAChR activation in an animal model of RA, and we could show that this resulted in reduced arthritis activity. Accordingly, stimulation of the CAP by vagus nerve stimulation improved experimental arthritis. Con …
This led us to study the effects of alpha7nAChR activation in an animal model of RA, and we could show that this resulted in reduced arthrit …
Vagus nerve-mediated neuroimmune modulation for rheumatoid arthritis: a pivotal randomized controlled trial.
Tesser JRP, Crowley AR, Box EJ, June JP, Wickersham PB, Valenzuela GJ, Gaylis NB, Lam GKW, Pacheco LA, Ridley DJ, Pinto-Patarroyo GP, Novack SN, Churchill MA, Kohler M, Lee EC, Pando JA, Parris GR, Peterson JR, Shah T, Singhal AK, Vuong V, Levine YA, Evangelista ML, Derosier AA, Curtis JR, Richardson RM, Chernoff D. Tesser JRP, et al. Nat Med. 2026 Jan;32(1):369-378. doi: 10.1038/s41591-025-04114-7. Epub 2025 Dec 22. Nat Med. 2026. PMID: 41429981 Free PMC article. Clinical Trial.
The inflammatory reflex, in which vagus nerve signaling modulates cytokine production, is dysregulated in rheumatoid arthritis (RA). ...Patients were randomized to active or sham stimulation for 3 months, and then all received open-label stimulation …
The inflammatory reflex, in which vagus nerve signaling modulates cytokine production, is dysregulated in rheumatoid ar …
Non-invasive vagus nerve stimulation for rheumatoid arthritis: a proof-of-concept study.
Marsal S, Corominas H, de Agustín JJ, Pérez-García C, López-Lasanta M, Borrell H, Reina D, Sanmartí R, Narváez J, Franco-Jarava C, Peterfy C, Narváez JA, Sharma V, Alataris K, Genovese MC, Baker MC. Marsal S, et al. Lancet Rheumatol. 2021 Apr;3(4):e262-e269. doi: 10.1016/S2665-9913(20)30425-2. Epub 2021 Feb 1. Lancet Rheumatol. 2021. PMID: 38279410
BACKGROUND: Vagus nerve stimulation delivered with an implanted device has been shown to improve rheumatoid arthritis severity. ...All eligible participants were assigned to use a non-invasive, wearable vagus nerve stimulation devi …
BACKGROUND: Vagus nerve stimulation delivered with an implanted device has been shown to improve rheumatoid arth …
Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through alpha7nAChR+ splenocytes.
Inoue T, Abe C, Sung SS, Moscalu S, Jankowski J, Huang L, Ye H, Rosin DL, Guyenet PG, Okusa MD. Inoue T, et al. J Clin Invest. 2016 May 2;126(5):1939-52. doi: 10.1172/JCI83658. Epub 2016 Apr 18. J Clin Invest. 2016. PMID: 27088805 Free PMC article.
The nervous and immune systems interact in complex ways to maintain homeostasis and respond to stress or injury, and rapid nerve conduction can provide instantaneous input for modulating inflammation. The inflammatory reflex referred to as the cholinergic antiinflammatory …
The nervous and immune systems interact in complex ways to maintain homeostasis and respond to stress or injury, and rapid nerve cond …
108 results