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1880 3
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1936 1
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1941 1
1943 1
1944 1
1945 3
1946 7
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1949 5
1950 8
1951 17
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1953 13
1954 12
1955 14
1956 9
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1959 13
1960 31
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1971 393
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1973 319
1974 380
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1976 309
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1978 254
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1982 273
1983 296
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1989 456
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1998 746
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2000 788
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2005 953
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2007 955
2008 944
2009 972
2010 977
2011 1003
2012 1044
2013 1033
2014 1051
2015 1164
2016 1241
2017 1229
2018 1258
2019 1210
2020 1246
2021 1292
2022 1259
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2025 1291
2026 768
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40,286 results

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Page 1
L-valine production in Corynebacterium glutamicum based on systematic metabolic engineering: progress and prospects.
Liu J, Xu JZ, Wang B, Rao ZM, Zhang WG. Liu J, et al. Amino Acids. 2021 Sep;53(9):1301-1312. doi: 10.1007/s00726-021-03066-9. Epub 2021 Aug 16. Amino Acids. 2021. PMID: 34401958 Review.
Market demand has stimulated people's interest in the industrial production of L-valine. At present, the mutagenized or engineered Corynebacterium glutamicum is an effective microbial cell factory for producing L-valine. ...This whole-cell-scale transformation strat …
Market demand has stimulated people's interest in the industrial production of L-valine. At present, the mutagenized or engineered Co …
Valine is a precursor of propionyl-CoA.
Kamoun P. Kamoun P. Trends Biochem Sci. 1992 May;17(5):175-6. doi: 10.1016/0968-0004(92)90258-b. Trends Biochem Sci. 1992. PMID: 1595124 Review.
For some time the metabolism of valine has been misrepresented by several biochemistry textbooks. This article demonstrates that propionyl-CoA occurs as an intermediate in the valine metabolic pathway before the formation of methylmalonyl CoA....
For some time the metabolism of valine has been misrepresented by several biochemistry textbooks. This article demonstrates that prop …
Engineering of microbial cells for L-valine production: challenges and opportunities.
Gao H, Tuyishime P, Zhang X, Yang T, Xu M, Rao Z. Gao H, et al. Microb Cell Fact. 2021 Aug 30;20(1):172. doi: 10.1186/s12934-021-01665-5. Microb Cell Fact. 2021. PMID: 34461907 Free PMC article. Review.
L-valine is an essential amino acid that has wide and expanding applications with a suspected growing market demand. ...Future prospects for enhancing the current L-valine production strategies are also discussed....
L-valine is an essential amino acid that has wide and expanding applications with a suspected growing market demand. ...Future prospe …
Valine improves mitochondrial function and protects against oxidative stress.
Sharma S, Zhang X, Azhar G, Patyal P, Verma A, Kc G, Wei JY. Sharma S, et al. Biosci Biotechnol Biochem. 2024 Jan 24;88(2):168-176. doi: 10.1093/bbb/zbad169. Biosci Biotechnol Biochem. 2024. PMID: 38093456 Free PMC article.
This study investigated valine effect on mitochondrial function and oxidative stress in vitro. Valine increased expression of genes involved in mitochondrial biogenesis and dynamics. ...Functional role of valine against oxidative stress was analyzed by XFe96 …
This study investigated valine effect on mitochondrial function and oxidative stress in vitro. Valine increased expression of …
Application and microbial preparation of D-valine.
Chen M, Shi C, Zhao J, Gao Z, Zhang C. Chen M, et al. World J Microbiol Biotechnol. 2016 Oct;32(10):171. doi: 10.1007/s11274-016-2119-z. Epub 2016 Aug 26. World J Microbiol Biotechnol. 2016. PMID: 27565781 Review.
Due to its widespread application, D-valine is gaining more and more attention and some approaches for D-valine preparation have been investigated. ...So far, microbial preparation of D-valine can be mainly classified into three categories: microbial asymmetr …
Due to its widespread application, D-valine is gaining more and more attention and some approaches for D-valine preparation ha …
Valine potentiates cefoperazone-sulbactam to kill methicillin-resistant Staphylococcus aureus.
Li S-h, Tao Y, Yang Z-c, Fu H-z, Lin H-y, Peng X-x, Li H. Li S-h, et al. mSystems. 2025 Jan 21;10(1):e0124424. doi: 10.1128/msystems.01244-24. Epub 2024 Dec 18. mSystems. 2025. PMID: 39692510 Free PMC article.
Viability of 18 clinical MRSA isolates was reduced by the top 276.64-fold in the presence of valine and SCF. In mouse models, lower bacterial load in liver, spleen, kidney, thigh, and higher survival were determined in the SCF + valine than valine or SCF alon …
Viability of 18 clinical MRSA isolates was reduced by the top 276.64-fold in the presence of valine and SCF. In mouse models, lower b …
Production of L-valine from metabolically engineered Corynebacterium glutamicum.
Wang X, Zhang H, Quinn PJ. Wang X, et al. Appl Microbiol Biotechnol. 2018 May;102(10):4319-4330. doi: 10.1007/s00253-018-8952-2. Epub 2018 Mar 29. Appl Microbiol Biotechnol. 2018. PMID: 29594358 Review.
L-Valine is one of the three branched-chain amino acids (valine, leucine, and isoleucine) essential for animal health and important in metabolism; therefore, it is widely added in the products of food, medicine, and feed. ...Industrially competitive L-valine- …
L-Valine is one of the three branched-chain amino acids (valine, leucine, and isoleucine) essential for animal health and impo …
Valine administration in the hypothalamus alters the brain and plasma metabolome in rainbow trout.
Comesaña S, Antomagesh F, Soengas JL, Blanco AM, Vijayan MM. Comesaña S, et al. Am J Physiol Regul Integr Comp Physiol. 2024 Aug 1;327(2):R261-R273. doi: 10.1152/ajpregu.00056.2024. Epub 2024 Jun 17. Am J Physiol Regul Integr Comp Physiol. 2024. PMID: 38881412 Free article.
Central administration of valine has been shown to cause hyperphagia in fish. Although mechanistic target of rapamycin (mTOR) is involved in this response, the contributions to feed intake of central and peripheral metabolite changes due to excess valine are unknown …
Central administration of valine has been shown to cause hyperphagia in fish. Although mechanistic target of rapamycin (mTOR) is invo …
l-valine supplementation disturbs vital molecular pathways and induces apoptosis in mouse testes.
Wu ZW, Wang L, Mou Q, Wang F, Wang Y, Fang T, Yin Z, Du ZQ, Yang CX. Wu ZW, et al. Theriogenology. 2024 Feb;215:31-42. doi: 10.1016/j.theriogenology.2023.11.020. Epub 2023 Nov 20. Theriogenology. 2024. PMID: 38000127
The branched-chain amino acids (BCAAs: leucine, isoleucine and valine) are essential for animal growth and metabolic health. However, the effect of valine on male reproduction and its underlying molecular mechanism remain largely unknown. Here, we showed that l-v …
The branched-chain amino acids (BCAAs: leucine, isoleucine and valine) are essential for animal growth and metabolic health. However, …
L-valine is a powerful stimulator of GLP-1 secretion in rodents and stimulates secretion through ATP-sensitive potassium channels and voltage-gated calcium channels.
Modvig IM, Smits MM, Galsgaard KD, Hjørne AP, Drzazga AK, Rosenkilde MM, Holst JJ. Modvig IM, et al. Nutr Diabetes. 2024 Jun 11;14(1):43. doi: 10.1038/s41387-024-00303-4. Nutr Diabetes. 2024. PMID: 38862477 Free PMC article.
This makes L-valine an interesting target for nutritional-based modulation of GLP-1 secretion. However, the molecular mechanism of L-valine-induced secretion remains unknown. ...CONCLUSIONS: L-valine is a powerful stimulator of GLP-1 release in rodents. We pr …
This makes L-valine an interesting target for nutritional-based modulation of GLP-1 secretion. However, the molecular mechanism of L- …
40,286 results
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