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Year Number of Results
1964 1
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1988 1
1989 1
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1995 2
1996 3
1997 2
1999 2
2002 3
2003 1
2004 1
2007 3
2008 1
2009 2
2012 1
2013 3
2014 4
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178 results

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Page 1
Gut Commensal Antibiotic-Resistant Parabacteroides goldsteinii Ameliorates Mouse Colitis through Valine-Isobutyrate Metabolism.
He N, Mu M, Li X, Hao Q, Chen K, Zhao X, Sun Y, Wang H, Wu Z, Liang H, Wang M, Xiao L, Yu T, Wang ZP, Peng J, Zou Y, Li S. He N, et al. Research (Wash D C). 2025 Sep 11;8:0867. doi: 10.34133/research.0867. eCollection 2025. Research (Wash D C). 2025. PMID: 40948937 Free PMC article.
Antibiotic cocktails (ABX) serve as potent therapeutic interventions for refractory ulcerative colitis (UC), yet invariably induce gut dysbiosis. This study demonstrates that pectin oligosaccharides synergistically enhance ABX efficacy by restoring gut microbiota ba …
Antibiotic cocktails (ABX) serve as potent therapeutic interventions for refractory ulcerative colitis (UC), yet invariably induce gut …
Branched Chain Amino Acids: Beyond Nutrition Metabolism.
Nie C, He T, Zhang W, Zhang G, Ma X. Nie C, et al. Int J Mol Sci. 2018 Mar 23;19(4):954. doi: 10.3390/ijms19040954. Int J Mol Sci. 2018. PMID: 29570613 Free PMC article. Review.
Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine (Val), play critical roles in the regulation of energy homeostasis, nutrition metabolism, gut health, immunity and disease in humans and animals. As the most abundant of essent …
Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine (Val), play critical roles in the regulatio …
L-valine derived from the gut microbiota protects sepsis-induced intestinal injury and negatively correlates with the severity of sepsis.
Chen Y, Sun K, Qi Y, Tang J, Zhu H, Wang Z. Chen Y, et al. Front Immunol. 2024 Jul 4;15:1424332. doi: 10.3389/fimmu.2024.1424332. eCollection 2024. Front Immunol. 2024. PMID: 39026673 Free PMC article.
In sepsis mouse experiments, it was found that L-valine could alleviate sepsis-induced intestinal damage. CONCLUSION: Alterations in microbial and metabolic features in the gut can affect the severity of sepsis. Furthermore, L-valine can protect agains …
In sepsis mouse experiments, it was found that L-valine could alleviate sepsis-induced intestinal damage. CONCLUSION: Alterati …
Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism.
Cheng H, Liu J, Zhang D, Wang J, Tan Y, Feng W, Peng C. Cheng H, et al. Front Immunol. 2022 May 17;13:817600. doi: 10.3389/fimmu.2022.817600. eCollection 2022. Front Immunol. 2022. PMID: 35655785 Free PMC article.
In addition, Rg1 also partly reversed the imbalance of gut microbiota composition caused by DSS. Rg1 intervention can regulate various metabolic pathways of gut microbiota such as valine, leucine, and isoleucine biosynthesis and vitamin B6 metabolism and the …
In addition, Rg1 also partly reversed the imbalance of gut microbiota composition caused by DSS. Rg1 intervention can regulate variou …
The Probiotic Parabacteroides johnsonii Ameliorates Metabolic Disorders Through Promoting BCAAs to BSCFAs Conversion.
Chen Y, Jiang S, Wang H, Si M, Wu H, Liang X, Yao S, Zhang Y, Wen X, Yang J. Chen Y, et al. Adv Sci (Weinh). 2025 Oct;12(38):e02624. doi: 10.1002/advs.202502624. Epub 2025 Aug 7. Adv Sci (Weinh). 2025. PMID: 40772426 Free PMC article.
The gut bacterium Parabacteroides spp. is increasingly recognized for its therapeutic potential in treating metabolic disorders. ...Oral administration of live P. johnsonii improved the metabolic dysfunction in high fat diet (HFD)-fed mice, accompanied by the alleviation o …
The gut bacterium Parabacteroides spp. is increasingly recognized for its therapeutic potential in treating metabolic disorders. ...O …
Dietary Valine Ameliorated Gut Health and Accelerated the Development of Nonalcoholic Fatty Liver Disease of Laying Hens.
Jian H, Miao S, Liu Y, Wang X, Xu Q, Zhou W, Li H, Dong X, Zou X. Jian H, et al. Oxid Med Cell Longev. 2021 Aug 23;2021:4704771. doi: 10.1155/2021/4704771. eCollection 2021. Oxid Med Cell Longev. 2021. Retraction in: Oxid Med Cell Longev. 2025 Oct 16;2025:9784052. doi: 10.1155/omcl/9784052. PMID: 34484560 Free PMC article. Retracted.
However, how long-term dietary valine impacts gut health and the development of nonalcoholic fatty liver disease (NAFLD) remains unknown. ...The results showed that diet supplemented with valine ameliorated gut health by improving intestinal vil …
However, how long-term dietary valine impacts gut health and the development of nonalcoholic fatty liver disease (NAFLD) remai …
Integrated Analyses of the Gut Microbiota, Intestinal Permeability, and Serum Metabolome Phenotype in Rats with Alcohol Withdrawal Syndrome.
Yang F, Wei J, Shen M, Ding Y, Lu Y, Ishaq HM, Li D, Yan D, Wang Q, Zhang R. Yang F, et al. Appl Environ Microbiol. 2021 Aug 26;87(18):e0083421. doi: 10.1128/AEM.00834-21. Epub 2021 Aug 26. Appl Environ Microbiol. 2021. PMID: 34190609 Free PMC article.
The aims of this study were to evaluate the effect of alcohol abuse on the gut microbiota, intestinal permeability and serum metabolic profile and to determine whether alcohol-induced alterations in gut microbiota are correlated with gut permeability a …
The aims of this study were to evaluate the effect of alcohol abuse on the gut microbiota, intestinal permeability and serum m …
Modulation of intestinal metabolites by calorie restriction and its association with gut microbiota in a xenograft model of colorectal cancer.
Zhang Y, Dong L, Dai X, Huang Y, Gao Y, Wang F. Zhang Y, et al. Discov Oncol. 2024 Feb 22;15(1):46. doi: 10.1007/s12672-024-00897-2. Discov Oncol. 2024. PMID: 38386206 Free PMC article.
Here, we aim to further investigate alteration in the intestinal metabolites and explore the interplay between gut microbiota and intestinal metabolites upon calorie restriction. ...The integrative analysis of gut microbiota and metabolites to elucidat …
Here, we aim to further investigate alteration in the intestinal metabolites and explore the interplay between gut microbiota …
Gut microbiome composition and metabolic activity in metabolic-associated fatty liver disease.
Zhang D, Wang Q, Li D, Chen S, Chen J, Zhu X, Bai F. Zhang D, et al. Virulence. 2025 Dec;16(1):2482158. doi: 10.1080/21505594.2025.2482158. Epub 2025 Mar 28. Virulence. 2025. PMID: 40122128 Free PMC article.
Between April 2023 and July 2023, 60 patients with MAFLD, along with 60 age, ethnicity, and sex-matched healthy controls (HCs), were enrolled from the Inner Mongolia Autonomous Region, China. Analysis of gut microbiota composition and plasma metabolic profiles was conducte …
Between April 2023 and July 2023, 60 patients with MAFLD, along with 60 age, ethnicity, and sex-matched healthy controls (HCs), were enrolle …
Gut microbiota's role in high-altitude cognitive impairment: the therapeutic potential of Clostridium sp. supplementation.
Zhou W, Zhou Y, Zhang S, Li B, Li Z, Bai Z, Sun D, Huangfu C, Wang N, Xia T, Huang C, Guan L, Yang X, Hu Y, Zhang P, Shen P, Wang R, Ni Z, Gao Y. Zhou W, et al. Sci China Life Sci. 2025 Apr;68(4):1132-1148. doi: 10.1007/s11427-024-2779-9. Epub 2024 Dec 18. Sci China Life Sci. 2025. PMID: 39704932
Additionally, compromised L-valine absorption due to intestinal barrier damage correlated with lower hippocampal glutamate levels and neurotrophic factors. Intervention with Clostridium sp. effectively restored the intestinal barrier and enhanced L-valine …
Additionally, compromised L-valine absorption due to intestinal barrier damage correlated with lower hippocampal glutamate lev …
178 results