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Page 1
Did you mean valproate neural tube defect pregnancy (291 results)?
Neural tube defects: a review of global prevalence, causes, and primary prevention.
Kancherla V. Kancherla V. Childs Nerv Syst. 2023 Jul;39(7):1703-1710. doi: 10.1007/s00381-023-05910-7. Epub 2023 Mar 8. Childs Nerv Syst. 2023. PMID: 36882610 Review.
Neural tube defects (NTDs) are common birth defects and contribute to life-long disabilities, high medical care costs, and perinatal and child mortality. ...NTDs have multiple risk factors including genetic and non-genetic (i.e., maternal nutritional s …
Neural tube defects (NTDs) are common birth defects and contribute to life-long disabilities, high medical care …
Epilepsy.
Benson R, Pack A. Benson R, et al. Handb Clin Neurol. 2020;172:155-167. doi: 10.1016/B978-0-444-64240-0.00009-X. Handb Clin Neurol. 2020. PMID: 32768086 Review.
Preconception counseling regarding contraception, folic acid, and antiseizure medications (ASMs) will maximize positive outcomes. Folic acid supplementation is recommended to decrease risk of neural tube defects, similar to the general populatio …
Preconception counseling regarding contraception, folic acid, and antiseizure medications (ASMs) will maximize positive outcomes. Fol …
Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After In Utero Exposure to Antiseizure Medication: Practice Guideline From the AAN, AES, and SMFM.
Pack AM, Oskoui M, Williams Roberson S, Donley DK, French J, Gerard EE, Gloss D, Miller WR, Munger Clary HM, Osmundson SS, McFadden B, Parratt K, Pennell PB, Saade G, Smith DB, Sullivan K, Thomas SV, Tomson T, Dolan O'Brien M, Botchway-Doe K, Silsbee HM, Keezer MR. Pack AM, et al. Neurology. 2024 Jun;102(11):e209279. doi: 10.1212/WNL.0000000000209279. Epub 2024 May 15. Neurology. 2024. PMID: 38748979 Free PMC article.
Clinicians must consider using lamotrigine, levetiracetam, or oxcarbazepine in PWECP when appropriate based on the patient's epilepsy syndrome, likelihood of achieving seizure control, and comorbidities, to minimize the risk of MCMs. Clinicians must avoid the use of valproic …
Clinicians must consider using lamotrigine, levetiracetam, or oxcarbazepine in PWECP when appropriate based on the patient's epilepsy syndro …
Valproic Acid in Pregnancy Revisited: Neurobehavioral, Biochemical and Molecular Changes Affecting the Embryo and Fetus in Humans and in Animals: A Narrative Review.
Ornoy A, Echefu B, Becker M. Ornoy A, et al. Int J Mol Sci. 2023 Dec 27;25(1):390. doi: 10.3390/ijms25010390. Int J Mol Sci. 2023. PMID: 38203562 Free PMC article. Review.
Valproic acid (VPA) is a very effective anticonvulsant and mood stabilizer with relatively few side effects. ...The more common congenital malformations are neural tube defects, cardiac anomalies, urogenital malformations including hypospadias, …
Valproic acid (VPA) is a very effective anticonvulsant and mood stabilizer with relatively few side effects. ...The more commo …
Valproate.
Bowden CL. Bowden CL. Bipolar Disord. 2003 Jun;5(3):189-202. doi: 10.1034/j.1399-5618.2003.00031.x. Bipolar Disord. 2003. PMID: 12780873 Review.
Valproate benefits a broader spectrum of bipolar conditions than lithium. Valproate appears at best modestly effective for bipolar depression. ...Weight gain and pharmacokinetic interaction with lamotrigine are perhaps the most consistent problems in use. Valproa …
Valproate benefits a broader spectrum of bipolar conditions than lithium. Valproate appears at best modestly effective for bip …
Etiology, pathogenesis and prevention of neural tube defects.
Padmanabhan R. Padmanabhan R. Congenit Anom (Kyoto). 2006 Jun;46(2):55-67. doi: 10.1111/j.1741-4520.2006.00104.x. Congenit Anom (Kyoto). 2006. PMID: 16732763 Review.
Spina bifida, anencephaly, and encephalocele are commonly grouped together and termed neural tube defects (NTD). Failure of closure of the neural tube during development results in anencephaly or spina bifida aperta but encephaloceles are possib …
Spina bifida, anencephaly, and encephalocele are commonly grouped together and termed neural tube defects (NTD). Failur …
Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects.
Steele JW, Lin YL, Chen N, Wlodarczyk BJ, Chen Q, Attarwala N, Venkatesalu M, Cabrera RM, Gross SS, Finnell RH. Steele JW, et al. Front Cell Dev Biol. 2022 Feb 21;10:832492. doi: 10.3389/fcell.2022.832492. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35265619 Free PMC article.
Valproic acid (VPA, valproate, Depakote) is a commonly used anti-seizure medication (ASM) in the treatment of epilepsy and a variety of other neurological disorders. While VPA and other ASMs are efficacious for management of seizures, they also increase the r …
Valproic acid (VPA, valproate, Depakote) is a commonly used anti-seizure medication (ASM) in the treatment of epilepsy …
Neural tube defects, folate, and immune modulation.
Denny KJ, Jeanes A, Fathe K, Finnell RH, Taylor SM, Woodruff TM. Denny KJ, et al. Birth Defects Res A Clin Mol Teratol. 2013 Sep;97(9):602-609. doi: 10.1002/bdra.23177. Birth Defects Res A Clin Mol Teratol. 2013. PMID: 24078477 Free PMC article. Review.
Periconceptional supplementation with folic acid has led to a significant worldwide reduction in the incidence of neural tube defects (NTDs). ...Furthermore, there exists a significant subgroup of women who appear to be resistant to the protective effe …
Periconceptional supplementation with folic acid has led to a significant worldwide reduction in the incidence of neural tu …
Epilepsy and pregnancy.
O'Brien MD, Gilmour-White S. O'Brien MD, et al. BMJ. 1993 Aug 21;307(6902):492-5. doi: 10.1136/bmj.307.6902.492. BMJ. 1993. PMID: 8400940 Free PMC article. Review.
The incidence of cleft palate and heart defects with phenytoin is 1.8% compared with 0.7% in the general population. With sodium valproate, neural tube defects occur in about 1.5% of pregnancies. Present evidence suggests that carbamazepi …
The incidence of cleft palate and heart defects with phenytoin is 1.8% compared with 0.7% in the general population. With sodium v …
Valproic acid-induced neural tube defects.
Nau H. Nau H. Ciba Found Symp. 1994;181:144-52; discussion 152-60. doi: 10.1002/9780470514559.ch9. Ciba Found Symp. 1994. PMID: 8005022 Review.
Antiepileptic drug therapy with valproic acid (VPA) during early pregnancy can result in a 1-2% incidence of spina bifida aperta, a closure defect of the posterior neural tube in the human. The predominant defect produced by VPA in the mouse is …
Antiepileptic drug therapy with valproic acid (VPA) during early pregnancy can result in a 1-2% incidence of spina bifi …
286 results