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Reduced Euchromatin histone methyltransferase 1 causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra syndrome mice.
Balemans MC, Ansar M, Oudakker AR, van Caam AP, Bakker B, Vitters EL, van der Kraan PM, de Bruijn DR, Janssen SM, Kuipers AJ, Huibers MM, Maliepaard EM, Walboomers XF, Benevento M, Nadif Kasri N, Kleefstra T, Zhou H, Van der Zee CE, van Bokhoven H. Balemans MC, et al. Dev Biol. 2014 Feb 15;386(2):395-407. doi: 10.1016/j.ydbio.2013.12.016. Epub 2013 Dec 19. Dev Biol. 2014. PMID: 24362066 Free article.
Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage.
Blaney Davidson EN, Vitters EL, Bennink MB, van Lent PL, van Caam AP, Blom AB, van den Berg WB, van de Loo FA, van der Kraan PM. Blaney Davidson EN, et al. Among authors: van der kraan pm, van lent pl, van de loo fa, van caam ap, van den berg wb. Ann Rheum Dis. 2015 Jun;74(6):1257-64. doi: 10.1136/annrheumdis-2013-204528. Epub 2014 Jan 21. Ann Rheum Dis. 2015. PMID: 24448347
TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?
Blaney Davidson EN, van Caam AP, Vitters EL, Bennink MB, Thijssen E, van den Berg WB, Koenders MI, van Lent PL, van de Loo FA, van der Kraan PM. Blaney Davidson EN, et al. Among authors: van der kraan pm, van lent pl, van de loo fa, van caam ap, van den berg wb. Osteoarthritis Cartilage. 2015 Mar;23(3):478-86. doi: 10.1016/j.joca.2014.12.005. Epub 2014 Dec 18. Osteoarthritis Cartilage. 2015. PMID: 25529198 Free article.
Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β.
Pieters BC, Arntz OJ, Bennink MB, Broeren MG, van Caam AP, Koenders MI, van Lent PL, van den Berg WB, de Vries M, van der Kraan PM, van de Loo FA. Pieters BC, et al. Among authors: van der kraan pm, van lent pl, van de loo fa, van caam ap, van den berg wb. PLoS One. 2015 Mar 30;10(3):e0121123. doi: 10.1371/journal.pone.0121123. eCollection 2015. PLoS One. 2015. PMID: 25822997 Free PMC article.
IL37 dampens the IL1β-induced catabolic status of human OA chondrocytes.
van Geffen EW, van Caam AP, van Beuningen HM, Vitters EL, Schreurs W, van de Loo FA, van Lent PL, Koenders MI, Blaney Davidson EN, van der Kraan PM. van Geffen EW, et al. Among authors: van der kraan pm, van lent pl, van de loo fa, van caam ap, van beuningen hm. Rheumatology (Oxford). 2017 Mar 1;56(3):351-361. doi: 10.1093/rheumatology/kew411. Rheumatology (Oxford). 2017. PMID: 27940589
Osteoarthritis year in review 2016: biology.
Blaney Davidson EN, van Caam AP, van der Kraan PM. Blaney Davidson EN, et al. Among authors: van der kraan pm, van caam ap. Osteoarthritis Cartilage. 2017 Feb;25(2):175-180. doi: 10.1016/j.joca.2016.09.024. Epub 2017 Jan 16. Osteoarthritis Cartilage. 2017. PMID: 28100421 Free article. Review.
IL-37 diminishes proteoglycan loss in human OA cartilage: donor-specific link between IL-37 and MMP-3.
van Geffen EW, van Caam APM, Schreurs W, van de Loo FA, van Lent PLEM, Koenders MI, Thudium CS, Bay-Jensen AC, Blaney Davidson EN, van der Kraan PM. van Geffen EW, et al. Among authors: van der kraan pm, van caam apm, van de loo fa, van lent plem. Osteoarthritis Cartilage. 2019 Jan;27(1):148-157. doi: 10.1016/j.joca.2018.08.016. Epub 2018 Sep 7. Osteoarthritis Cartilage. 2019. PMID: 30201492 Free article.
Unraveling SSc Pathophysiology; The Myofibroblast.
van Caam A, Vonk M, van den Hoogen F, van Lent P, van der Kraan P. van Caam A, et al. Among authors: van lent p, van den hoogen f, van der kraan p. Front Immunol. 2018 Nov 13;9:2452. doi: 10.3389/fimmu.2018.02452. eCollection 2018. Front Immunol. 2018. PMID: 30483246 Free PMC article. Review.
35 results