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3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition.
Antolino-Lobo I, Meulenbelt J, Nijmeijer SM, Maas-Bakker RF, Meijerman I, van den Berg M, van Duursen MB. Antolino-Lobo I, et al. Among authors: van den berg m, van duursen mb. Toxicol Lett. 2011 May 30;203(1):82-91. doi: 10.1016/j.toxlet.2011.03.007. Epub 2011 Mar 22. Toxicol Lett. 2011. PMID: 21402137
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