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Genetic analysis of the two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway.
Koudijs MJ, den Broeder MJ, Groot E, van Eeden FJ. Koudijs MJ, et al. Among authors: van eeden fj. BMC Dev Biol. 2008 Feb 19;8:15. doi: 10.1186/1471-213X-8-15. BMC Dev Biol. 2008. PMID: 18284698 Free PMC article.
A zebrafish model for VHL and hypoxia signaling.
van Rooijen E, Santhakumar K, Logister I, Voest E, Schulte-Merker S, Giles R, van Eeden F. van Rooijen E, et al. Among authors: van eeden f. Methods Cell Biol. 2011;105:163-90. doi: 10.1016/B978-0-12-381320-6.00007-2. Methods Cell Biol. 2011. PMID: 21951530
Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia.
van Rooijen E, Voest EE, Logister I, Korving J, Schwerte T, Schulte-Merker S, Giles RH, van Eeden FJ. van Rooijen E, et al. Among authors: van eeden fj. Blood. 2009 Jun 18;113(25):6449-60. doi: 10.1182/blood-2008-07-167890. Epub 2009 Mar 20. Blood. 2009. PMID: 19304954
von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish.
van Rooijen E, Voest EE, Logister I, Bussmann J, Korving J, van Eeden FJ, Giles RH, Schulte-Merker S. van Rooijen E, et al. Among authors: van eeden fj. Dis Model Mech. 2010 May-Jun;3(5-6):343-53. doi: 10.1242/dmm.004036. Epub 2010 Mar 24. Dis Model Mech. 2010. PMID: 20335444
Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.
Maurya AK, Ben J, Zhao Z, Lee RT, Niah W, Ng AS, Iyu A, Yu W, Elworthy S, van Eeden FJ, Ingham PW. Maurya AK, et al. Among authors: van eeden fj. PLoS Genet. 2013;9(12):e1003955. doi: 10.1371/journal.pgen.1003955. Epub 2013 Dec 5. PLoS Genet. 2013. PMID: 24339784 Free PMC article.
Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential.
Thomas NA, Koudijs M, van Eeden FJ, Joyner AL, Yelon D. Thomas NA, et al. Among authors: van eeden fj. Development. 2008 Nov;135(22):3789-99. doi: 10.1242/dev.024083. Epub 2008 Oct 8. Development. 2008. PMID: 18842815 Free PMC article.
Repression of Hedgehog signalling is required for the acquisition of dorsolateral cell fates in the zebrafish otic vesicle.
Hammond KL, van Eeden FJ, Whitfield TT. Hammond KL, et al. Among authors: van eeden fj. Development. 2010 Apr;137(8):1361-71. doi: 10.1242/dev.045666. Epub 2010 Mar 10. Development. 2010. PMID: 20223756 Free PMC article.
The zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway.
Koudijs MJ, den Broeder MJ, Keijser A, Wienholds E, Houwing S, van Rooijen EM, Geisler R, van Eeden FJ. Koudijs MJ, et al. Among authors: van rooijen em, van eeden fj. PLoS Genet. 2005 Aug;1(2):e19. doi: 10.1371/journal.pgen.0010019. Epub 2005 Aug 19. PLoS Genet. 2005. PMID: 16121254 Free PMC article.
Genetic variation in the zebrafish.
Guryev V, Koudijs MJ, Berezikov E, Johnson SL, Plasterk RH, van Eeden FJ, Cuppen E. Guryev V, et al. Among authors: van eeden fj. Genome Res. 2006 Apr;16(4):491-7. doi: 10.1101/gr.4791006. Epub 2006 Mar 13. Genome Res. 2006. PMID: 16533913 Free PMC article.
Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish.
Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ. Wilkinson RN, et al. Among authors: van eeden fj. Blood. 2012 Jul 12;120(2):477-88. doi: 10.1182/blood-2011-10-383729. Epub 2012 Jun 5. Blood. 2012. PMID: 22668851 Free PMC article.
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