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Polymorphisms in the enhancer region of the thymidylate synthase gene are associated with thymidylate synthase levels in normal tissues but not in malignant tissues of patients with colorectal cancer.
Mauritz R, Giovannetti E, Beumer IJ, Smid K, Van Groeningen CJ, Pinedo HM, Peters GJ. Mauritz R, et al. Among authors: van groeningen cj. Clin Colorectal Cancer. 2009 Jul;8(3):146-54. doi: 10.3816/CCC.2009.n.024. Clin Colorectal Cancer. 2009. PMID: 19632929
A phase I study of monohydroxyethylrutoside in healthy volunteers.
Willems AM, Bruynzeel AM, Kedde MA, van Groeningen CJ, Bast A, van der Vijgh WJ. Willems AM, et al. Among authors: van groeningen cj, van der vijgh wj. Cancer Chemother Pharmacol. 2006 May;57(5):678-84. doi: 10.1007/s00280-005-0083-7. Epub 2005 Sep 1. Cancer Chemother Pharmacol. 2006. PMID: 16136309 Clinical Trial.
Clinical activity and benefit of irinotecan (CPT-11) in patients with colorectal cancer truly resistant to 5-fluorouracil (5-FU).
Van Cutsem E, Cunningham D, Ten Bokkel Huinink WW, Punt CJ, Alexopoulos CG, Dirix L, Symann M, Blijham GH, Cholet P, Fillet G, Van Groeningen C, Vannetzel JM, Levi F, Panagos G, Unger C, Wils J, Cote C, Blanc C, Hérait P, Bleiberg H. Van Cutsem E, et al. Among authors: van groeningen c. Eur J Cancer. 1999 Jan;35(1):54-9. doi: 10.1016/s0959-8049(98)00353-0. Eur J Cancer. 1999. PMID: 10211088 Clinical Trial.
Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer.
van Zweeden AA, van Groeningen CJ, Honeywell RJ, Giovannetti E, Ruijter R, Smorenburg CH, Giaccone G, Verheul HMW, Peters GJ, van der Vliet HJ. van Zweeden AA, et al. Among authors: van groeningen cj. Cancer Chemother Pharmacol. 2018 Jul;82(1):39-48. doi: 10.1007/s00280-018-3588-6. Epub 2018 Apr 25. Cancer Chemother Pharmacol. 2018. PMID: 29696360 Free PMC article. Clinical Trial.
A phase I and pharmacokinetic study of gemcitabine given by 24-h hepatic arterial infusion.
van Riel JM, Peters GJ, Mammatas LH, Honeywell RJ, Laan AC, Ruyter R, van den Berg FG, Giaccone G, van Groeningen CJ. van Riel JM, et al. Among authors: van groeningen cj, van den berg fg. Eur J Cancer. 2009 Sep;45(14):2519-27. doi: 10.1016/j.ejca.2009.05.025. Epub 2009 Jun 24. Eur J Cancer. 2009. PMID: 19556122 Clinical Trial.
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