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Genomic instability and cancer: scanning the Caenorhabditis elegans genome for tumor suppressors.
van Haaften G, Plasterk RH, Tijsterman M. van Haaften G, et al. Oncogene. 2004 Nov 1;23(51):8366-75. doi: 10.1038/sj.onc.1208011. Oncogene. 2004. PMID: 15517018 Review.
Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi.
Pothof J, van Haaften G, Thijssen K, Kamath RS, Fraser AG, Ahringer J, Plasterk RH, Tijsterman M. Pothof J, et al. Among authors: van haaften g. Genes Dev. 2003 Feb 15;17(4):443-8. doi: 10.1101/gad.1060703. Genes Dev. 2003. PMID: 12600937 Free PMC article.
Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation.
Nollen EA, Garcia SM, van Haaften G, Kim S, Chavez A, Morimoto RI, Plasterk RH. Nollen EA, et al. Among authors: van haaften g. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6403-8. doi: 10.1073/pnas.0307697101. Epub 2004 Apr 14. Proc Natl Acad Sci U S A. 2004. PMID: 15084750 Free PMC article.
Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality.
van Haaften G, Vastenhouw NL, Nollen EA, Plasterk RH, Tijsterman M. van Haaften G, et al. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12992-6. doi: 10.1073/pnas.0403131101. Epub 2004 Aug 23. Proc Natl Acad Sci U S A. 2004. PMID: 15326288 Free PMC article.
Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi.
van Haaften G, Romeijn R, Pothof J, Koole W, Mullenders LH, Pastink A, Plasterk RH, Tijsterman M. van Haaften G, et al. Curr Biol. 2006 Jul 11;16(13):1344-50. doi: 10.1016/j.cub.2006.05.047. Curr Biol. 2006. PMID: 16824923
The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2alpha.
Gort EH, van Haaften G, Verlaan I, Groot AJ, Plasterk RH, Shvarts A, Suijkerbuijk KP, van Laar T, van der Wall E, Raman V, van Diest PJ, Tijsterman M, Vooijs M. Gort EH, et al. Among authors: van laar t, van der wall e, van haaften g, van diest pj. Oncogene. 2008 Mar 6;27(11):1501-10. doi: 10.1038/sj.onc.1210795. Epub 2007 Sep 17. Oncogene. 2008. PMID: 17873906
RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans.
Frische EW, Pellis-van Berkel W, van Haaften G, Cuppen E, Plasterk RH, Tijsterman M, Bos JL, Zwartkruis FJ. Frische EW, et al. Among authors: van haaften g. EMBO J. 2007 Dec 12;26(24):5083-92. doi: 10.1038/sj.emboj.7601922. Epub 2007 Nov 8. EMBO J. 2007. PMID: 17989692 Free PMC article.
Germline mutations affecting the histone H4 core cause a developmental syndrome by altering DNA damage response and cell cycle control.
Tessadori F, Giltay JC, Hurst JA, Massink MP, Duran K, Vos HR, van Es RM; Deciphering Developmental Disorders Study, Scott RH, van Gassen KLI, Bakkers J, van Haaften G. Tessadori F, et al. Among authors: van es rm, van gassen kli, van haaften g. Nat Genet. 2017 Nov;49(11):1642-1646. doi: 10.1038/ng.3956. Epub 2017 Sep 18. Nat Genet. 2017. PMID: 28920961
Effective CRISPR/Cas9-based nucleotide editing in zebrafish to model human genetic cardiovascular disorders.
Tessadori F, Roessler HI, Savelberg SMC, Chocron S, Kamel SM, Duran KJ, van Haelst MM, van Haaften G, Bakkers J. Tessadori F, et al. Among authors: van haelst mm, van haaften g. Dis Model Mech. 2018 Oct 18;11(10):dmm035469. doi: 10.1242/dmm.035469. Dis Model Mech. 2018. PMID: 30355756 Free PMC article.
Expanding the spectrum of phenotypes associated with germline PIGA mutations: a child with developmental delay, accelerated linear growth, facial dysmorphisms, elevated alkaline phosphatase, and progressive CNS abnormalities.
van der Crabben SN, Harakalova M, Brilstra EH, van Berkestijn FM, Hofstede FC, van Vught AJ, Cuppen E, Kloosterman W, Ploos van Amstel HK, van Haaften G, van Haelst MM. van der Crabben SN, et al. Among authors: van haelst mm, van haaften g, van berkestijn fm, van vught aj. Am J Med Genet A. 2014 Jan;164A(1):29-35. doi: 10.1002/ajmg.a.36184. Epub 2013 Nov 20. Am J Med Genet A. 2014. PMID: 24259184 Review.
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