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Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D(3).
van Halteren AG, van Etten E, de Jong EC, Bouillon R, Roep BO, Mathieu C. van Halteren AG, et al. Diabetes. 2002 Jul;51(7):2119-25. doi: 10.2337/diabetes.51.7.2119. Diabetes. 2002. PMID: 12086941
Islet inflammation and CXCL10 in recent-onset type 1 diabetes.
Roep BO, Kleijwegt FS, van Halteren AG, Bonato V, Boggi U, Vendrame F, Marchetti P, Dotta F. Roep BO, et al. Clin Exp Immunol. 2010 Mar;159(3):338-43. doi: 10.1111/j.1365-2249.2009.04087.x. Epub 2010 Jan 5. Clin Exp Immunol. 2010. PMID: 20059481 Free PMC article.
Modulation of autoimmunity to beta-cell antigens by proteases.
Roep BO, van den Engel NK, van Halteren AG, Duinkerken G, Martin S. Roep BO, et al. Diabetologia. 2002 May;45(5):686-92. doi: 10.1007/s00125-002-0797-6. Epub 2002 Mar 28. Diabetologia. 2002. PMID: 12107749
Homing of human autoreactive T cells into pancreatic tissue of NOD-scid mice.
van Halteren AG, Kardol MJ, Mulder A, Roep BO. van Halteren AG, et al. Diabetologia. 2005 Jan;48(1):75-82. doi: 10.1007/s00125-004-1613-2. Epub 2004 Dec 24. Diabetologia. 2005. PMID: 15619074
Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells.
Greening JE, Tree TI, Kotowicz KT, van Halteren AG, Roep BO, Klein NJ, Peakman M. Greening JE, et al. Diabetes. 2003 Mar;52(3):717-25. doi: 10.2337/diabetes.52.3.717. Diabetes. 2003. PMID: 12606513
Cord blood comprises antigen-experienced T cells specific for maternal minor histocompatibility antigen HA-1.
Mommaas B, Stegehuis-Kamp JA, van Halteren AG, Kester M, Enczmann J, Wernet P, Kögler G, Mutis T, Brand A, Goulmy E. Mommaas B, et al. Blood. 2005 Feb 15;105(4):1823-7. doi: 10.1182/blood-2004-07-2832. Epub 2004 Oct 21. Blood. 2005. PMID: 15498856
Promiscuity of the AlloHLA-A2 restricted T cell repertoire hampers the generation of minor Histocompatibility antigen-specific cytotoxic T cells across HLA barriers.
Oosten LE, Blokland E, Kester MG, Falkenburg JH, van Halteren AG, Goulmy E. Oosten LE, et al. Biol Blood Marrow Transplant. 2007 Feb;13(2):151-63. doi: 10.1016/j.bbmt.2006.10.025. Biol Blood Marrow Transplant. 2007. PMID: 17241921
1alpha,25-dihydroxyvitamin D3 or analogue treated dendritic cells modulate human autoreactive T cells via the selective induction of apoptosis.
van Halteren AG, Tysma OM, van Etten E, Mathieu C, Roep BO. van Halteren AG, et al. J Autoimmun. 2004 Nov;23(3):233-9. doi: 10.1016/j.jaut.2004.06.004. J Autoimmun. 2004. PMID: 15501394
Artificial antigen-presenting constructs efficiently stimulate minor histocompatibility antigen-specific cytotoxic T lymphocytes.
Oosten LE, Blokland E, van Halteren AG, Curtsinger J, Mescher MF, Falkenburg JH, Mutis T, Goulmy E. Oosten LE, et al. Blood. 2004 Jul 1;104(1):224-6. doi: 10.1182/blood-2003-07-2461. Epub 2004 Mar 18. Blood. 2004. PMID: 15031203
TAP-inhibiting proteins US6, ICP47 and UL49.5 differentially affect minor and major histocompatibility antigen-specific recognition by cytotoxic T lymphocytes.
Oosten LE, Koppers-Lalic D, Blokland E, Mulder A, Ressing ME, Mutis T, van Halteren AG, Wiertz EJ, Goulmy E. Oosten LE, et al. Int Immunol. 2007 Sep;19(9):1115-22. doi: 10.1093/intimm/dxm082. Int Immunol. 2007. PMID: 17855435
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