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The ubiquitin-proteasome pathway and the regulation of growth hormone receptor availability.
Strous GJ, van Kerkhof P. Strous GJ, et al. Among authors: van kerkhof p. Mol Cell Endocrinol. 2002 Nov 29;197(1-2):143-51. doi: 10.1016/s0303-7207(02)00258-7. Mol Cell Endocrinol. 2002. PMID: 12431807 Review.
Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway.
Melman L, Geuze HJ, Li Y, McCormick LM, Van Kerkhof P, Strous GJ, Schwartz AL, Bu G. Melman L, et al. Among authors: van kerkhof p. Mol Biol Cell. 2002 Sep;13(9):3325-35. doi: 10.1091/mbc.e02-03-0152. Mol Biol Cell. 2002. PMID: 12221136 Free PMC article.
Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport.
Hassink G, Slotman J, Oorschot V, Van Der Reijden BA, Monteferrario D, Noordermeer SM, Van Kerkhof P, Klumperman J, Strous GJ. Hassink G, et al. Among authors: van kerkhof p. Biol Open. 2012 Jun 15;1(6):607-14. doi: 10.1242/bio.2012778. Epub 2012 May 9. Biol Open. 2012. PMID: 23213454 Free PMC article.
Ubc13 and COOH terminus of Hsp70-interacting protein (CHIP) are required for growth hormone receptor endocytosis.
Slotman JA, da Silva Almeida AC, Hassink GC, van de Ven RH, van Kerkhof P, Kuiken HJ, Strous GJ. Slotman JA, et al. Among authors: van kerkhof p. J Biol Chem. 2012 May 4;287(19):15533-43. doi: 10.1074/jbc.M111.302521. Epub 2012 Mar 20. J Biol Chem. 2012. PMID: 22433856 Free PMC article.
Jak2 is a negative regulator of ubiquitin-dependent endocytosis of the growth hormone receptor.
Putters J, da Silva Almeida AC, van Kerkhof P, van Rossum AG, Gracanin A, Strous GJ. Putters J, et al. Among authors: van kerkhof p. PLoS One. 2011 Feb 9;6(2):e14676. doi: 10.1371/journal.pone.0014676. PLoS One. 2011. PMID: 21347402 Free PMC article.
SCF(TrCP) acts in endosomal sorting of the GH receptor.
van Kerkhof P, Westgeest M, Hassink G, Strous GJ. van Kerkhof P, et al. Exp Cell Res. 2011 Apr 15;317(7):1071-82. doi: 10.1016/j.yexcr.2010.12.020. Epub 2010 Dec 30. Exp Cell Res. 2011. PMID: 21195069 Free article.
The ubiquitin ligase SCF(betaTrCP) regulates the degradation of the growth hormone receptor.
van Kerkhof P, Putters J, Strous GJ. van Kerkhof P, et al. J Biol Chem. 2007 Jul 13;282(28):20475-83. doi: 10.1074/jbc.M702610200. Epub 2007 May 10. J Biol Chem. 2007. PMID: 17500058 Free article.
The growth hormone receptor interacts with its sheddase, the tumour necrosis factor-alpha-converting enzyme (TACE).
Schantl JA, Roza M, Van Kerkhof P, Strous GJ. Schantl JA, et al. Among authors: van kerkhof p. Biochem J. 2004 Jan 15;377(Pt 2):379-84. doi: 10.1042/BJ20031321. Biochem J. 2004. PMID: 14519102 Free PMC article.
A method to increase the number of growth hormone receptors at the surface of cells.
van Kerkhof P, Vallon E, Strous GJ. van Kerkhof P, et al. Mol Cell Endocrinol. 2003 Mar 28;201(1-2):57-62. doi: 10.1016/s0303-7207(02)00434-3. Mol Cell Endocrinol. 2003. PMID: 12706294
Dimerization and signal transduction of the growth hormone receptor.
Gent J, Van Den Eijnden M, Van Kerkhof P, Strous GJ. Gent J, et al. Among authors: van den eijnden m, van kerkhof p. Mol Endocrinol. 2003 May;17(5):967-75. doi: 10.1210/me.2002-0261. Epub 2003 Feb 6. Mol Endocrinol. 2003. PMID: 12576487
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