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Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease.
Lee RG, Balasubramaniam S, Stentenbach M, Kralj T, McCubbin T, Padman B, Smith J, Riley LG, Priyadarshi A, Peng L, Nuske MR, Webster R, Peacock K, Roberts P, Stark Z, Lemire G, Ito YA; Care4Rare Canada Consortium; Boycott KM, Geraghty MT, van Klinken JB, Ferdinandusse S, Zhou Y, Walsh R, Marcellin E, Thorburn DR, Rosciolli T, Fletcher J, Rackham O, Vaz FM, Reid GE, Filipovska A. Lee RG, et al. Among authors: van klinken jb. Hum Mol Genet. 2022 Oct 28;31(21):3597-3612. doi: 10.1093/hmg/ddac040. Hum Mol Genet. 2022. PMID: 35147173 Free PMC article.
Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity.
Coomans CP, van den Berg SA, Houben T, van Klinken JB, van den Berg R, Pronk AC, Havekes LM, Romijn JA, van Dijk KW, Biermasz NR, Meijer JH. Coomans CP, et al. Among authors: van dijk kw, van klinken jb, van den berg sa, van den berg r. FASEB J. 2013 Apr;27(4):1721-32. doi: 10.1096/fj.12-210898. Epub 2013 Jan 9. FASEB J. 2013. PMID: 23303208
Discovery of novel diagnostic biomarkers for Sjögren-Larsson syndrome by untargeted lipidomics.
Vaz FM, Staps P, van Klinken JB, van Lenthe H, Vervaart M, Wanders RJA, Pras-Raves ML, van Weeghel M, Salomons GS, Ferdinandusse S, Wevers RA, Willemsen MAAP. Vaz FM, et al. Among authors: van klinken jb. Biochim Biophys Acta Mol Cell Biol Lipids. 2024 Mar;1869(2):159447. doi: 10.1016/j.bbalip.2023.159447. Epub 2024 Jan 3. Biochim Biophys Acta Mol Cell Biol Lipids. 2024. PMID: 38181883 Free article.
Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation.
Held NM, Kuipers EN, van Weeghel M, van Klinken JB, Denis SW, Lombès M, Wanders RJ, Vaz FM, Rensen PCN, Verhoeven AJ, Boon MR, Houtkooper RH. Held NM, et al. Among authors: van weeghel m, van klinken jb. Sci Rep. 2018 Jun 22;8(1):9562. doi: 10.1038/s41598-018-27875-3. Sci Rep. 2018. PMID: 29934543 Free PMC article.
The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South Asian and Europid men.
Nahon KJ, Janssen LGM, Sardjoe Mishre ASD, Bilsen MP, van der Eijk JA, Botani K, Overduin LA, Ruiz JR, Burakiewicz J, Dzyubachyk O, Webb AG, Kan HE, Berbée JFP, van Klinken JB, van Dijk KW, van Weeghel M, Vaz FM, Coskun T, Jazet IM, Kooijman S, Martinez-Tellez B, Boon MR, Rensen PCN. Nahon KJ, et al. Among authors: van weeghel m, van der eijk ja, van dijk kw, van klinken jb. Diabetes Obes Metab. 2020 Nov;22(11):2032-2044. doi: 10.1111/dom.14120. Epub 2020 Jul 29. Diabetes Obes Metab. 2020. PMID: 32558052 Free PMC article. Clinical Trial.
Alterations in ether lipid metabolism and the consequences for the mouse lipidome.
Lackner K, Sailer S, van Klinken JB, Wever E, Pras-Raves ML, Dane AD, Honsho M, Abe Y, Keller MA, Golderer G, Werner-Felmayer G, Fujiki Y, Vaz FM, Werner ER, Watschinger K. Lackner K, et al. Among authors: van klinken jb. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Apr;1868(4):159285. doi: 10.1016/j.bbalip.2023.159285. Epub 2023 Jan 21. Biochim Biophys Acta Mol Cell Biol Lipids. 2023. PMID: 36690320 Free article.
Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue.
van Eenige R, In Het Panhuis W, Schönke M, Jouffe C, Devilee TH, Siebeler R, Streefland TCM, Sips HCM, Pronk ACM, Vorderman RHP, Mei H, van Klinken JB, van Weeghel M, Uhlenhaut NH, Kersten S, Rensen PCN, Kooijman S. van Eenige R, et al. Among authors: van weeghel m, van klinken jb. Mol Metab. 2022 Jun;60:101497. doi: 10.1016/j.molmet.2022.101497. Epub 2022 Apr 10. Mol Metab. 2022. PMID: 35413480 Free PMC article.
63 results