van Leeuwen F - Search Results

1

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

Stulemeijer IJ, De Vos D, van Harten K, Joshi OK, Blomberg O, van Welsem T, Terweij M, Vlaming H, de Graaf EL, Altelaar AF, Bakker BM, van Leeuwen F. Stulemeijer IJ, et al. Among authors: van leeuwen f, van welsem t, van harten k. Sci Rep. 2015 May 12;5:9824. doi: 10.1038/srep09824. Sci Rep. 2015. PMID: 25965993 Free PMC article.

2

Synthetic lethal screens identify gene silencing processes in yeast and implicate the acetylated amino terminus of Sir3 in recognition of the nucleosome core.

van Welsem T, Frederiks F, Verzijlbergen KF, Faber AW, Nelson ZW, Egan DA, Gottschling DE, van Leeuwen F. van Welsem T, et al. Among authors: van leeuwen f. Mol Cell Biol. 2008 Jun;28(11):3861-72. doi: 10.1128/MCB.02050-07. Epub 2008 Apr 7. Mol Cell Biol. 2008. PMID: 18391024 Free PMC article.

3

Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.

Frederiks F, Tzouros M, Oudgenoeg G, van Welsem T, Fornerod M, Krijgsveld J, van Leeuwen F. Frederiks F, et al. Among authors: van leeuwen f, van welsem t. Nat Struct Mol Biol. 2008 Jun;15(6):550-7. doi: 10.1038/nsmb.1432. Epub 2008 May 30. Nat Struct Mol Biol. 2008. PMID: 18511943

4

Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae.

Verzijlbergen KF, Faber AW, Stulemeijer IJ, van Leeuwen F. Verzijlbergen KF, et al. Among authors: van leeuwen f. BMC Mol Biol. 2009 Jul 28;10:76. doi: 10.1186/1471-2199-10-76. BMC Mol Biol. 2009. PMID: 19638198 Free PMC article.

5

Two Dot1 isoforms in Saccharomyces cerevisiae as a result of leaky scanning by the ribosome.

Frederiks F, Heynen GJ, van Deventer SJ, Janssen H, van Leeuwen F. Frederiks F, et al. Among authors: van deventer sj, van leeuwen f. Nucleic Acids Res. 2009 Nov;37(21):7047-58. doi: 10.1093/nar/gkp765. Nucleic Acids Res. 2009. PMID: 19778927 Free PMC article.

6

Recombination-induced tag exchange to track old and new proteins.

Verzijlbergen KF, Menendez-Benito V, van Welsem T, van Deventer SJ, Lindstrom DL, Ovaa H, Neefjes J, Gottschling DE, van Leeuwen F. Verzijlbergen KF, et al. Among authors: van deventer sj, van leeuwen f, van welsem t. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):64-8. doi: 10.1073/pnas.0911164107. Epub 2009 Dec 14. Proc Natl Acad Sci U S A. 2010. PMID: 20018668 Free PMC article.

7

Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei.

Frederiks F, van Welsem T, Oudgenoeg G, Heck AJ, Janzen CJ, van Leeuwen F. Frederiks F, et al. Among authors: van leeuwen f, van welsem t. J Cell Sci. 2010 Dec 1;123(Pt 23):4019-23. doi: 10.1242/jcs.073882. J Cell Sci. 2010. PMID: 21084562

8

A modified epigenetics toolbox to study histone modifications on the nucleosome core.

Frederiks F, Stulemeijer IJ, Ovaa H, van Leeuwen F. Frederiks F, et al. Among authors: van leeuwen f. Chembiochem. 2011 Jan 24;12(2):308-13. doi: 10.1002/cbic.201000617. Epub 2010 Dec 29. Chembiochem. 2011. PMID: 21243718 Review.

9

Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.

Stulemeijer IJ, Pike BL, Faber AW, Verzijlbergen KF, van Welsem T, Frederiks F, Lenstra TL, Holstege FC, Gasser SM, van Leeuwen F. Stulemeijer IJ, et al. Among authors: van leeuwen f, van welsem t. Epigenetics Chromatin. 2011 Feb 3;4(1):2. doi: 10.1186/1756-8935-4-2. Epigenetics Chromatin. 2011. PMID: 21291527 Free PMC article.

10

Patterns and mechanisms of ancestral histone protein inheritance in budding yeast.

Radman-Livaja M, Verzijlbergen KF, Weiner A, van Welsem T, Friedman N, Rando OJ, van Leeuwen F. Radman-Livaja M, et al. Among authors: van leeuwen f, van welsem t. PLoS Biol. 2011 Jun;9(6):e1001075. doi: 10.1371/journal.pbio.1001075. Epub 2011 Jun 7. PLoS Biol. 2011. PMID: 21666805 Free PMC article.

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