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Page 1
Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.
Billmann M, Costanzo M, Zhang X, Hassan AZ, Rahman M, Brown KR, Chan KS, Tong AHY, Pons C, Ward HN, Ross C, van Leeuwen J, Aregger M, Lawson KA, Mair B, Roth AF, Sen NE, Forster DT, Tan G, Mero P, Masud SN, Lee Y, Aguilera-Uribe M, Ušaj M, Almeida SMT, Aulakh K, Bhojoo U, Birkadze S, Budijono N, Cai X, Caumanns JJ, Chalmers JJ, Chandrashekhar M, Chang D, Climie R, Dasgupta K, Drazic A, Echenique JIR, Gacesa R, Farias AG, Habsid A, Horecka I, Kantautas K, Ji F, Kim DK, Lee SY, Liang W, Lim HJ, Lin K, Lu X, Maier M, Nami B, Nixon A, Mikolajewicz N, Mokhtaridoost M, Nedyalkova L, Rohde T, Rodrigues MS, Soste M, Schultz E, Wang W, Seetharaman A, Shuteriqi E, Sizova O, Taylor DT, Tereshchenko M, Tieu D, Turowec J, Ubhi T, Varland S, Wang KE, Wang ZY, Wei J, Xiao YX, Maass PG, Reversade B, Brown GW, Cravatt BF, Dixon SJ, Wyatt HDM, Röst HL, Roth FP, Xia T, Bader GD, Loewith R, Davis NG, Andrews B, Myers CL, Moffat J, Boone C. Billmann M, et al. Among authors: van leeuwen j. Cell. 2026 Apr 27:S0092-8674(26)00345-4. doi: 10.1016/j.cell.2026.03.044. Online ahead of print. Cell. 2026. PMID: 42049019 Free article.
The modifiers that cause changes in gene essentiality.
Batté A, Bosch-Guiteras N, Pons C, Ota M, Lopes M, Sharma S, Tellini N, Paltenghi C, Conti M, Kan KT, Ho UL, Wiederkehr M, Barraud J, Ashe M, Aloy P, Liti G, Chabes A, Parts L, van Leeuwen J. Batté A, et al. Among authors: van leeuwen j. Cell Syst. 2026 Apr 15;17(4):101515. doi: 10.1016/j.cels.2025.101515. Epub 2026 Mar 2. Cell Syst. 2026. PMID: 41775267 Free article.
What is the current bottleneck in mapping molecular interaction networks?
Skinnider MA, Luck K, Mukhtar MS, Garrido-Rodriguez M, Saez-Rodriguez J, van Leeuwen J, Beltrao P, Carvunis AR, Taipale M, Emili A, Bulyk ML, Krogan NJ. Skinnider MA, et al. Among authors: van leeuwen j. Cell Syst. 2025 May 21;16(5):101295. doi: 10.1016/j.cels.2025.101295. Cell Syst. 2025. PMID: 40403700 No abstract available.
Land-use intensification reshapes microbial phosphorus cycling, organic matter composition, and phosphorus fractions in Amazonian soils.
Martins GL, Monteiro GGTN, Lange M, de Freitas AS, do Nascimento Silva Barbosa L, van Leeuwen J, de Carvalho Soares JE, Hanada RE, Gleixner G, Tsai SM. Martins GL, et al. Among authors: van leeuwen j. ISME Commun. 2026 Feb 24;6(1):ycag027. doi: 10.1093/ismeco/ycag027. eCollection 2026 Jan. ISME Commun. 2026. PMID: 41756353 Free PMC article.
Safety of laparoscopic oophorectomy in a Dutch national pediatric cancer cohort.
Clasen NHZ, van der Perk MEM, van de Wetering MD, Bos AME, van der Kooi ALF, van Loon K, Veening MA, IJgosse IM, Neggers SJCMM, van Grotel M, Bresters D, van Santen HM, Verpoest WMJA, Looijenga LHJ, Arends B, van Leeuwen J, Broer SL, van der Steeg AFW, van den Heuvel-Eibrink MM. Clasen NHZ, et al. Among authors: van leeuwen j. F S Rep. 2025 Dec 2;7(1):69-80. doi: 10.1016/j.xfre.2025.11.008. eCollection 2026 Feb. F S Rep. 2025. PMID: 41694257 Free PMC article.
Quantitative analysis of genetic interactions in human cells from genome-wide CRISPR-Cas9 screens.
Billmann M, Costanzo M, Rahman M, Chan K, Yan Tong AH, Ward HN, Hassan AZ, Zhang X, Brown KR, Rohde T, Shaw AH, Ross C, van Leeuwen J, Aregger M, Lawson K, Mair B, Mero P, Usaj M, Andrews B, Boone C, Moffat J, Myers CL. Billmann M, et al. Among authors: van leeuwen j. bioRxiv [Preprint]. 2026 Jan 5:2025.06.30.662330. doi: 10.1101/2025.06.30.662330. bioRxiv. 2026. PMID: 41542642 Free PMC article. Preprint.
874 results