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Crystalloid or colloid fluid loading and pulmonary permeability, edema, and injury in septic and nonseptic critically ill patients with hypovolemia.
van der Heijden M, Verheij J, van Nieuw Amerongen GP, Groeneveld AB. van der Heijden M, et al. Crit Care Med. 2009 Apr;37(4):1275-81. doi: 10.1097/CCM.0b013e31819cedfd. Crit Care Med. 2009. PMID: 19242338 Clinical Trial.
Intracellular signalling involved in modulating human endothelial barrier function.
van Hinsbergh VW, van Nieuw Amerongen GP. van Hinsbergh VW, et al. J Anat. 2002 Jun;200(6):549-60. doi: 10.1046/j.1469-7580.2002.00060.x. J Anat. 2002. PMID: 12162723 Free PMC article. Review.
Endothelial hyperpermeability in vascular leakage.
van Hinsbergh VW, van Nieuw Amerongen GP. van Hinsbergh VW, et al. Vascul Pharmacol. 2002 Nov;39(4-5):171-2. doi: 10.1016/s1537-1891(03)00006-5. Vascul Pharmacol. 2002. PMID: 12747957 Review. No abstract available.
Effect of prior statin therapy on capillary permeability in the lungs after cardiac or vascular surgery.
van de Visse EP, van der Heijden M, Verheij J, van Nieuw Amerongen GP, van Hinsbergh VW, Girbes AR, Groeneveld AB. van de Visse EP, et al. Eur Respir J. 2006 May;27(5):1026-32. doi: 10.1183/09031936.06.00099405. Eur Respir J. 2006. PMID: 16707397
Angiopoietin-2, permeability oedema, occurrence and severity of ALI/ARDS in septic and non-septic critically ill patients.
van der Heijden M, van Nieuw Amerongen GP, Koolwijk P, van Hinsbergh VW, Groeneveld AB. van der Heijden M, et al. Thorax. 2008 Oct;63(10):903-9. doi: 10.1136/thx.2007.087387. Epub 2008 Jun 17. Thorax. 2008. PMID: 18559364 Clinical Trial.
The angiopoietin-Tie2 system as a therapeutic target in sepsis and acute lung injury.
van der Heijden M, van Nieuw Amerongen GP, Chedamni S, van Hinsbergh VW, Johan Groeneveld AB. van der Heijden M, et al. Expert Opin Ther Targets. 2009 Jan;13(1):39-53. doi: 10.1517/14728220802626256. Expert Opin Ther Targets. 2009. PMID: 19063705 Review.
The interaction of soluble Tie2 with angiopoietins and pulmonary vascular permeability in septic and nonseptic critically ill patients.
van der Heijden M, van Nieuw Amerongen GP, van Hinsbergh VW, Groeneveld AB. van der Heijden M, et al. Shock. 2010 Mar;33(3):263-8. doi: 10.1097/SHK.0b013e3181b2f978. Shock. 2010. PMID: 19543148
Circulating angiopoietin-2 levels in the course of septic shock: relation with fluid balance, pulmonary dysfunction and mortality.
van der Heijden M, Pickkers P, van Nieuw Amerongen GP, van Hinsbergh VW, Bouw MP, van der Hoeven JG, Groeneveld AB. van der Heijden M, et al. Intensive Care Med. 2009 Sep;35(9):1567-74. doi: 10.1007/s00134-009-1560-y. Epub 2009 Jun 24. Intensive Care Med. 2009. PMID: 19551369 Free PMC article.
A plethora of angiopoietin-2 effects during clinical sepsis.
van Nieuw Amerongen GP, Groeneveld AB. van Nieuw Amerongen GP, et al. Crit Care. 2010;14(3):166. doi: 10.1186/cc9053. Epub 2010 Jun 17. Crit Care. 2010. PMID: 20587077 Free PMC article.
Plasma protein levels are markers of pulmonary vascular permeability and degree of lung injury in critically ill patients with or at risk for acute lung injury/acute respiratory distress syndrome.
Aman J, van der Heijden M, van Lingen A, Girbes AR, van Nieuw Amerongen GP, van Hinsbergh VW, Groeneveld AB. Aman J, et al. Crit Care Med. 2011 Jan;39(1):89-97. doi: 10.1097/CCM.0b013e3181feb46a. Crit Care Med. 2011. PMID: 21057316
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