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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells.
van de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, Hurlstone A, van der Horn K, Batlle E, Coudreuse D, Haramis AP, Tjon-Pon-Fong M, Moerer P, van den Born M, Soete G, Pals S, Eilers M, Medema R, Clevers H. van de Wetering M, et al. Among authors: van den born m, van der horn k, de lau w. Cell. 2002 Oct 18;111(2):241-50. doi: 10.1016/s0092-8674(02)01014-0. Cell. 2002. PMID: 12408868
The Intestinal Wnt/TCF Signature.
Van der Flier LG, Sabates-Bellver J, Oving I, Haegebarth A, De Palo M, Anti M, Van Gijn ME, Suijkerbuijk S, Van de Wetering M, Marra G, Clevers H. Van der Flier LG, et al. Among authors: de palo m, van gijn me, van de wetering m. Gastroenterology. 2007 Feb;132(2):628-32. doi: 10.1053/j.gastro.2006.08.039. Epub 2006 Aug 18. Gastroenterology. 2007. PMID: 17320548
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells.
Hatzis P, van der Flier LG, van Driel MA, Guryev V, Nielsen F, Denissov S, Nijman IJ, Koster J, Santo EE, Welboren W, Versteeg R, Cuppen E, van de Wetering M, Clevers H, Stunnenberg HG. Hatzis P, et al. Among authors: van der flier lg, van de wetering m, van driel ma. Mol Cell Biol. 2008 Apr;28(8):2732-44. doi: 10.1128/MCB.02175-07. Epub 2008 Feb 11. Mol Cell Biol. 2008. PMID: 18268006 Free PMC article.
The intestinal stem cell.
Barker N, van de Wetering M, Clevers H. Barker N, et al. Among authors: van de wetering m. Genes Dev. 2008 Jul 15;22(14):1856-64. doi: 10.1101/gad.1674008. Genes Dev. 2008. PMID: 18628392 Free PMC article. Review.
Crypt stem cells as the cells-of-origin of intestinal cancer.
Barker N, Ridgway RA, van Es JH, van de Wetering M, Begthel H, van den Born M, Danenberg E, Clarke AR, Sansom OJ, Clevers H. Barker N, et al. Among authors: van den born m, van es jh, van de wetering m. Nature. 2009 Jan 29;457(7229):608-11. doi: 10.1038/nature07602. Epub 2008 Dec 17. Nature. 2009. PMID: 19092804
Transcription factor achaete scute-like 2 controls intestinal stem cell fate.
van der Flier LG, van Gijn ME, Hatzis P, Kujala P, Haegebarth A, Stange DE, Begthel H, van den Born M, Guryev V, Oving I, van Es JH, Barker N, Peters PJ, van de Wetering M, Clevers H. van der Flier LG, et al. Among authors: van gijn me, van den born m, van es jh, van de wetering m. Cell. 2009 Mar 6;136(5):903-12. doi: 10.1016/j.cell.2009.01.031. Cell. 2009. PMID: 19269367
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