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Page 1
Efficient Vascularization of Kidney Organoids through Intracelomic Transplantation in Chicken Embryos.
Koning M, Lievers E, Jaffredo T, van den Berg CW, Rabelink TJ. Koning M, et al. Among authors: van den berg cw. J Vis Exp. 2023 Feb 17;(192). doi: 10.3791/65090. J Vis Exp. 2023. PMID: 36876942
Kidney organoids derived from human induced pluripotent stem cells contain nephron-like structures that resemble those in the adult kidney to a certain degree. ...
Kidney organoids derived from human induced pluripotent stem cells contain nephron-like structures that resemble those in the adult k …
Human iPSC-derived preclinical models to identify toxicity of tumor-specific T cells with clinical potential.
van Amerongen RA, Morton LT, Chaudhari UG, Remst DFG, Hagedoorn RS, van den Berg CW, Freund C, Falkenburg JHF, Heemskerk MHM. van Amerongen RA, et al. Among authors: van den berg cw. Mol Ther Methods Clin Dev. 2023 Jan 20;28:249-261. doi: 10.1016/j.omtm.2023.01.005. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2023. PMID: 36816758 Free PMC article.
In vitro screening options against vital organs or specialized cell subsets would be preferably included in preclinical pipelines, but options remain limited. Here, we set up preclinical models with human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes, epicar …
In vitro screening options against vital organs or specialized cell subsets would be preferably included in preclinical pipelines, but optio …
Inhibition of complement activation by CD55 overexpression in human induced pluripotent stem cell derived kidney organoids.
Gaykema LH, van Nieuwland RY, Dekkers MC, van Essen MF, Heidt S, Zaldumbide A, van den Berg CW, Rabelink TJ, van Kooten C. Gaykema LH, et al. Among authors: van den berg cw. Front Immunol. 2023 Jan 12;13:1058763. doi: 10.3389/fimmu.2022.1058763. eCollection 2022. Front Immunol. 2023. PMID: 36713440 Free PMC article.
In this study we investigate whether inhibition of the complement system in human induced pluripotent stem cells (iPSC) could provide protection from such immune injury. ...
In this study we investigate whether inhibition of the complement system in human induced pluripotent stem cells (iPSC) could provide …
Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation.
Wang G, Heijs B, Kostidis S, Rietjens RGJ, Koning M, Yuan L, Tiemeier GL, Mahfouz A, Dumas SJ, Giera M, Kers J, Chuva de Sousa Lopes SM, van den Berg CW, van den Berg BM, Rabelink TJ. Wang G, et al. Among authors: van den berg cw. Cell Stem Cell. 2022 Nov 3;29(11):1580-1593.e7. doi: 10.1016/j.stem.2022.10.008. Cell Stem Cell. 2022. PMID: 36332571 Free article.
Vasculogenesis in kidney organoids upon transplantation.
Koning M, Dumas SJ, Avramut MC, Koning RI, Meta E, Lievers E, Wiersma LE, Borri M, Liang X, Xie L, Liu P, Chen F, Lin L, Luo Y, Mulder J, Spijker HS, Jaffredo T, van den Berg BM, Carmeliet P, van den Berg CW, Rabelink TJ. Koning M, et al. Among authors: van den berg cw. NPJ Regen Med. 2022 Aug 19;7(1):40. doi: 10.1038/s41536-022-00237-4. NPJ Regen Med. 2022. PMID: 35986027 Free PMC article.
Human induced pluripotent stem cell-derived kidney organoids have potential for disease modeling and to be developed into clinically transplantable auxiliary tissue. ...
Human induced pluripotent stem cell-derived kidney organoids have potential for disease modeling and to be developed into clinically …
Toward Human Models of Cardiorenal Syndrome in vitro.
Gabbin B, Meraviglia V, Mummery CL, Rabelink TJ, van Meer BJ, van den Berg CW, Bellin M. Gabbin B, et al. Among authors: van den berg cw. Front Cardiovasc Med. 2022 May 26;9:889553. doi: 10.3389/fcvm.2022.889553. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35694669 Free PMC article. Review.
CRS represents an exemplary disease illustrating the need to develop more complex models to study organ-organ interaction in-a-dish. Human induced pluripotent stem cells in combination with microfluidic chips are one powerful tool with potential to recapitulate the charact …
CRS represents an exemplary disease illustrating the need to develop more complex models to study organ-organ interaction in-a-dish. Human i …
Large-scale engineering of hiPSC-derived nephron sheets and cryopreservation of their progenitors.
Wiersma LE, Avramut MC, Lievers E, Rabelink TJ, van den Berg CW. Wiersma LE, et al. Among authors: van den berg cw. Stem Cell Res Ther. 2022 May 16;13(1):208. doi: 10.1186/s13287-022-02881-5. Stem Cell Res Ther. 2022. PMID: 35578313 Free PMC article.
BACKGROUND: The generation of human induced pluripotent stem cells (hiPSCs) has opened a world of opportunities for stem cell-based therapies in regenerative medicine. ...
BACKGROUND: The generation of human induced pluripotent stem cells (hiPSCs) has opened a world of opportunities for stem cell-based t …
Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition.
Geuens T, Ruiter FAA, Schumacher A, Morgan FLC, Rademakers T, Wiersma LE, van den Berg CW, Rabelink TJ, Baker MB, LaPointe VLS. Geuens T, et al. Among authors: van den berg cw. Biomaterials. 2021 Aug;275:120976. doi: 10.1016/j.biomaterials.2021.120976. Epub 2021 Jun 19. Biomaterials. 2021. PMID: 34198162 Free article.
Differentiated kidney organoids from induced pluripotent stem cells hold promise as a treatment for patients with kidney diseases. ...
Differentiated kidney organoids from induced pluripotent stem cells hold promise as a treatment for patients with kidney diseases. .. …
In Vivo Assessment of Size-Selective Glomerular Sieving in Transplanted Human Induced Pluripotent Stem Cell-Derived Kidney Organoids.
van den Berg CW, Koudijs A, Ritsma L, Rabelink TJ. van den Berg CW, et al. J Am Soc Nephrol. 2020 May;31(5):921-929. doi: 10.1681/ASN.2019060573. J Am Soc Nephrol. 2020. PMID: 32354986 Free PMC article.
Recent studies have demonstrated the vascularization and subsequent maturation of human pluripotent stem cell-derived kidney organoids after renal subcapsular transplantation. ...We also observed evidence of proximal tubular dextran reuptake. CONCLUSIONS: Our results demon …
Recent studies have demonstrated the vascularization and subsequent maturation of human pluripotent stem cell-derived kidney organoid …
Lowering the increased intracellular pH of human-induced pluripotent stem cell-derived endothelial cells induces formation of mature Weibel-Palade bodies.
Tiemeier GL, de Koning R, Wang G, Kostidis S, Rietjens RGJ, Sol WMPJ, Dumas SJ, Giera M, van den Berg CW, Eikenboom JCJ, van den Berg BM, Carmeliet P, Rabelink TJ. Tiemeier GL, et al. Among authors: van den berg cw. Stem Cells Transl Med. 2020 Jul;9(7):758-772. doi: 10.1002/sctm.19-0392. Epub 2020 Mar 12. Stem Cells Transl Med. 2020. PMID: 32163224 Free PMC article.
Differentiation of human-induced pluripotent stem cells (hiPSCs) into vascular endothelium is of great importance to tissue engineering, disease modeling, and use in regenerative medicine. ...
Differentiation of human-induced pluripotent stem cells (hiPSCs) into vascular endothelium is of great importance to tissue engineeri …
19 results