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Translational control of gene expression during hypoxia.
van den Beucken T, Koritzinsky M, Wouters BG. van den Beucken T, et al. Cancer Biol Ther. 2006 Jul;5(7):749-55. doi: 10.4161/cbt.5.7.2972. Epub 2006 Jul 1. Cancer Biol Ther. 2006. PMID: 16861930 Review.
Quantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxia.
Adriaens ME, Prickaerts P, Chan-Seng-Yue M, van den Beucken T, Dahlmans VEH, Eijssen LM, Beck T, Wouters BG, Voncken JW, Evelo CTA. Adriaens ME, et al. Among authors: van den beucken t. Epigenetics Chromatin. 2016 Nov 1;9:48. doi: 10.1186/s13072-016-0090-4. eCollection 2016. Epigenetics Chromatin. 2016. PMID: 27822313 Free PMC article.
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. Among authors: van den beucken t, van der kogel aj. J Clin Invest. 2010 Jan;120(1):127-41. doi: 10.1172/JCI40027. Epub 2009 Dec 14. J Clin Invest. 2010. PMID: 20038797 Free PMC article.
PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.
Rouschop KM, Dubois LJ, Keulers TG, van den Beucken T, Lambin P, Bussink J, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. Among authors: van den beucken t, van der kogel aj. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4622-7. doi: 10.1073/pnas.1210633110. Epub 2013 Mar 7. Proc Natl Acad Sci U S A. 2013. PMID: 23471998 Free PMC article.
Regulation of TRIB3 mRNA and protein in breast cancer.
Wennemers M, Bussink J, van den Beucken T, Sweep FC, Span PN. Wennemers M, et al. Among authors: van den beucken t. PLoS One. 2012;7(11):e49439. doi: 10.1371/journal.pone.0049439. Epub 2012 Nov 20. PLoS One. 2012. PMID: 23185332 Free PMC article.
Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction.
Rouschop KM, Dubois L, Schaaf MB, van den Beucken T, Lieuwes N, Keulers TG, Savelkouls KG, Bussink J, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. Among authors: van den beucken t, van der kogel aj. Radiother Oncol. 2011 Jun;99(3):385-91. doi: 10.1016/j.radonc.2011.05.047. Epub 2011 Jun 12. Radiother Oncol. 2011. PMID: 21665307
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