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VCP/p97-Mediated Unfolding as a Principle in Protein Homeostasis and Signaling.
van den Boom J, Meyer H. van den Boom J, et al. Mol Cell. 2018 Jan 18;69(2):182-194. doi: 10.1016/j.molcel.2017.10.028. Epub 2017 Nov 16. Mol Cell. 2018. PMID: 29153394 Review.
Sonic hedgehog shedding results in functional activation of the solubilized protein.
Ohlig S, Farshi P, Pickhinke U, van den Boom J, Höing S, Jakuschev S, Hoffmann D, Dreier R, Schöler HR, Dierker T, Bordych C, Grobe K. Ohlig S, et al. Dev Cell. 2011 Jun 14;20(6):764-74. doi: 10.1016/j.devcel.2011.05.010. Dev Cell. 2011. PMID: 21664575
VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.
van den Boom J, Wolf M, Weimann L, Schulze N, Li F, Kaschani F, Riemer A, Zierhut C, Kaiser M, Iliakis G, Funabiki H, Meyer H. van den Boom J, et al. Mol Cell. 2016 Oct 6;64(1):189-198. doi: 10.1016/j.molcel.2016.08.037. Mol Cell. 2016. PMID: 27716483 Free PMC article.
A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases.
Pöhler R, Krahn JH, van den Boom J, Dobrynin G, Kaschani F, Eggenweiler HM, Zenke FT, Kaiser M, Meyer H. Pöhler R, et al. Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1576-1580. doi: 10.1002/anie.201711429. Epub 2018 Jan 15. Angew Chem Int Ed Engl. 2018. PMID: 29271116
Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.
Weith M, Seiler J, van den Boom J, Kracht M, Hülsmann J, Primorac I, Del Pino Garcia J, Kaschani F, Kaiser M, Musacchio A, Bollen M, Meyer H. Weith M, et al. Among authors: van den boom j. Mol Cell. 2018 Nov 15;72(4):766-777.e6. doi: 10.1016/j.molcel.2018.09.020. Epub 2018 Oct 18. Mol Cell. 2018. PMID: 30344098 Free article.
Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase.
Blueggel M, van den Boom J, Meyer H, Bayer P, Beuck C. Blueggel M, et al. Among authors: van den boom j. Biomolecules. 2019 Dec 14;9(12):876. doi: 10.3390/biom9120876. Biomolecules. 2019. PMID: 31847414 Free PMC article.
Peptidyl succinimidyl peptides as taspase 1 inhibitors.
van den Boom J, Mamić M, Baccelliere D, Zweerink S, Kaschani F, Knauer S, Bayer P, Kaiser M. van den Boom J, et al. Chembiochem. 2014 Oct 13;15(15):2233-7. doi: 10.1002/cbic.201402108. Epub 2014 Aug 21. Chembiochem. 2014. PMID: 25146997
The other side of the corona: nanoparticles inhibit the protease taspase1 in a size-dependent manner.
van den Boom J, Hensel A, Trusch F, Matena A, Siemer S, Guel D, Docter D, Höing A, Bayer P, Stauber RH, Knauer SK. van den Boom J, et al. Nanoscale. 2020 Jul 14. doi: 10.1039/d0nr01631d. Online ahead of print. Nanoscale. 2020. PMID: 32662484
A heterodimer of human 3'-phospho-adenosine-5'-phosphosulphate (PAPS) synthases is a new sulphate activating complex.
Grum D, van den Boom J, Neumann D, Matena A, Link NM, Mueller JW. Grum D, et al. Biochem Biophys Res Commun. 2010 May 7;395(3):420-5. doi: 10.1016/j.bbrc.2010.04.039. Epub 2010 Apr 9. Biochem Biophys Res Commun. 2010. PMID: 20382111
Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1.
van den Boom J, Trusch F, Hoppstock L, Beuck C, Bayer P. van den Boom J, et al. PLoS One. 2016 Mar 14;11(3):e0151431. doi: 10.1371/journal.pone.0151431. eCollection 2016. PLoS One. 2016. PMID: 26974973 Free PMC article.
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