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Modified tumour antigen-encoding mRNA facilitates the analysis of naturally occurring and vaccine-induced CD4 and CD8 T cells in cancer patients.
Knights AJ, Nuber N, Thomson CW, de la Rosa O, Jäger E, Tiercy JM, van den Broek M, Pascolo S, Knuth A, Zippelius A. Knights AJ, et al. Among authors: van den broek m. Cancer Immunol Immunother. 2009 Mar;58(3):325-38. doi: 10.1007/s00262-008-0556-8. Epub 2008 Jul 29. Cancer Immunol Immunother. 2009. PMID: 18663444
Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC.
Martinic MM, van den Broek MF, Rülicke T, Huber C, Odermatt B, Reith W, Horvath E, Zellweger R, Fink K, Recher M, Eschli B, Hengartner H, Zinkernagel RM. Martinic MM, et al. Among authors: van den broek mf. Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14435-40. doi: 10.1073/pnas.0606707103. Epub 2006 Sep 18. Proc Natl Acad Sci U S A. 2006. PMID: 16983067 Free PMC article.
Dendritic cells break bonds to tolerize.
van den Broek M. van den Broek M. Immunity. 2007 Oct;27(4):544-6. doi: 10.1016/j.immuni.2007.10.004. Immunity. 2007. PMID: 17967408 Review.
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