van den Broek NJ - Search Results

1

Mdm2 induces mono-ubiquitination of FOXO4.

Brenkman AB, de Keizer PL, van den Broek NJ, Jochemsen AG, Burgering BM. Brenkman AB, et al. Among authors: van den broek nj. PLoS One. 2008 Jul 30;3(7):e2819. doi: 10.1371/journal.pone.0002819. PLoS One. 2008. PMID: 18665269 Free PMC article.

2

The DNA damage repair protein Ku70 interacts with FOXO4 to coordinate a conserved cellular stress response.

Brenkman AB, van den Broek NJ, de Keizer PL, van Gent DC, Burgering BM. Brenkman AB, et al. Among authors: van gent dc, van den broek nj. FASEB J. 2010 Nov;24(11):4271-80. doi: 10.1096/fj.10-158717. Epub 2010 Jun 22. FASEB J. 2010. PMID: 20570964

3

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP.

van der Horst A, de Vries-Smits AM, Brenkman AB, van Triest MH, van den Broek N, Colland F, Maurice MM, Burgering BM. van der Horst A, et al. Nat Cell Biol. 2006 Oct;8(10):1064-73. doi: 10.1038/ncb1469. Epub 2006 Sep 10. Nat Cell Biol. 2006. PMID: 16964248

4

The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors.

Brenkman AB, de Keizer PL, van den Broek NJ, van der Groep P, van Diest PJ, van der Horst A, Smits AM, Burgering BM. Brenkman AB, et al. Among authors: van der groep p, van den broek nj, van diest pj, van der horst a. Cancer Res. 2008 Sep 15;68(18):7597-605. doi: 10.1158/0008-5472.CAN-08-1059. Cancer Res. 2008. PMID: 18794148

5

Phosphorylation of Not4p functions parallel to BUR2 to regulate resistance to cellular stresses in Saccharomyces cerevisiae.

Lau NC, Mulder KW, Brenkman AB, Mohammed S, van den Broek NJ, Heck AJ, Timmers HT. Lau NC, et al. Among authors: van den broek nj. PLoS One. 2010 Apr 8;5(4):e9864. doi: 10.1371/journal.pone.0009864. PLoS One. 2010. PMID: 20386698 Free PMC article.

6

Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence.

de Keizer PL, Packer LM, Szypowska AA, Riedl-Polderman PE, van den Broek NJ, de Bruin A, Dansen TB, Marais R, Brenkman AB, Burgering BM. de Keizer PL, et al. Among authors: van den broek nj. Cancer Res. 2010 Nov 1;70(21):8526-36. doi: 10.1158/0008-5472.CAN-10-1563. Epub 2010 Oct 19. Cancer Res. 2010. PMID: 20959475 Free PMC article.

7

The serine/threonine phosphatase PPM1B (PP2Cβ) selectively modulates PPARγ activity.

Tasdelen I, van Beekum O, Gorbenko O, Fleskens V, van den Broek NJ, Koppen A, Hamers N, Berger R, Coffer PJ, Brenkman AB, Kalkhoven E. Tasdelen I, et al. Among authors: van den broek nj, van beekum o. Biochem J. 2013 Apr 1;451(1):45-53. doi: 10.1042/BJ20121113. Biochem J. 2013. PMID: 23320500

8

A protocol for quantifying lipid peroxidation in cellular systems by F2-isoprostane analysis.

Labuschagne CF, van den Broek NJ, Postma P, Berger R, Brenkman AB. Labuschagne CF, et al. Among authors: van den broek nj. PLoS One. 2013 Nov 14;8(11):e80935. doi: 10.1371/journal.pone.0080935. eCollection 2013. PLoS One. 2013. PMID: 24244726 Free PMC article.

9

SIRT1 mediates FOXA2 breakdown by deacetylation in a nutrient-dependent manner.

van Gent R, Di Sanza C, van den Broek NJ, Fleskens V, Veenstra A, Stout GJ, Brenkman AB. van Gent R, et al. Among authors: van den broek nj. PLoS One. 2014 May 29;9(5):e98438. doi: 10.1371/journal.pone.0098438. eCollection 2014. PLoS One. 2014. PMID: 24875183 Free PMC article.

10

Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling.

Kruiswijk F, Hasenfuss SC, Sivapatham R, Baar MP, Putavet D, Naipal KA, van den Broek NJ, Kruit W, van der Spek PJ, van Gent DC, Brenkman AB, Campisi J, Burgering BM, Hoeijmakers JH, de Keizer PL. Kruiswijk F, et al. Among authors: van der spek pj, van gent dc, van den broek nj. Oncogene. 2016 Apr 28;35(17):2166-77. doi: 10.1038/onc.2015.282. Epub 2015 Aug 17. Oncogene. 2016. PMID: 26279295 Free PMC article.

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