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G1/S Inhibitors and the SWI/SNF Complex Control Cell-Cycle Exit during Muscle Differentiation.
Ruijtenberg S, van den Heuvel S. Ruijtenberg S, et al. Cell. 2015 Jul 16;162(2):300-313. doi: 10.1016/j.cell.2015.06.013. Epub 2015 Jul 2. Cell. 2015. PMID: 26144318
Muscle precursor cells missing either SWI/SNF or G1/S inhibitor function could still arrest cell division, while simultaneous inactivation of these regulators caused continued proliferation and a C. elegans tumor phenotype. ...Thus, SWI/SNF and G1/S inhibitors provi …
Muscle precursor cells missing either SWI/SNF or G1/S inhibitor function could still arrest cell division, while simultaneous inactiv …
LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans.
Lorson MA, Horvitz HR, van den Heuvel S. Lorson MA, et al. J Cell Biol. 2000 Jan 10;148(1):73-86. doi: 10.1083/jcb.148.1.73. J Cell Biol. 2000. PMID: 10629219 Free PMC article.
Our results show that LIN-5 is a novel component of the spindle apparatus required for chromosome and spindle movements, cytoplasmic cleavage, and correct alternation of the S and M phases of the cell cycle....
Our results show that LIN-5 is a novel component of the spindle apparatus required for chromosome and spindle movements, cytoplasmic cleavag …
DOCK4, a GTPase activator, is disrupted during tumorigenesis.
Yajnik V, Paulding C, Sordella R, McClatchey AI, Saito M, Wahrer DC, Reynolds P, Bell DW, Lake R, van den Heuvel S, Settleman J, Haber DA. Yajnik V, et al. Cell. 2003 Mar 7;112(5):673-84. doi: 10.1016/s0092-8674(03)00155-7. Cell. 2003. PMID: 12628187
The C. elegans Polycomb gene SOP-2 encodes an RNA binding protein.
Zhang H, Christoforou A, Aravind L, Emmons SW, van den Heuvel S, Haber DA. Zhang H, et al. Mol Cell. 2004 Jun 18;14(6):841-7. doi: 10.1016/j.molcel.2004.06.001. Mol Cell. 2004. PMID: 15200961
The CDC-14 phosphatase controls developmental cell-cycle arrest in C. elegans.
Saito RM, Perreault A, Peach B, Satterlee JS, van den Heuvel S. Saito RM, et al. Nat Cell Biol. 2004 Aug;6(8):777-83. doi: 10.1038/ncb1154. Epub 2004 Jul 11. Nat Cell Biol. 2004. PMID: 15247923
The C. elegans cell cycle: overview of molecules and mechanisms.
van den Heuvel S. van den Heuvel S. Methods Mol Biol. 2005;296:51-67. Methods Mol Biol. 2005. PMID: 15576926 Review.
Cell-cycle control in Caenorhabditis elegans: how the worm moves from G1 to S.
Koreth J, van den Heuvel S. Koreth J, et al. Oncogene. 2005 Apr 18;24(17):2756-64. doi: 10.1038/sj.onc.1208607. Oncogene. 2005. PMID: 15838512 Review.
Coordination of cell proliferation and differentiation: finding a GEM in the root?
Wildwater M, The I, van den Heuvel S. Wildwater M, et al. Dev Cell. 2007 Jun;12(6):841-2. doi: 10.1016/j.devcel.2007.05.005. Dev Cell. 2007. PMID: 17543854 Review.
Replication licensing: oops! ... I did it again.
Korzelius J, van den Heuvel S. Korzelius J, et al. Curr Biol. 2007 Aug 21;17(16):R630-2. doi: 10.1016/j.cub.2007.06.029. Curr Biol. 2007. PMID: 17714648
Cell-cycle regulation.
van den Heuvel S. van den Heuvel S. WormBook. 2005 Sep 21:1-16. doi: 10.1895/wormbook.1.28.1. WormBook. 2005. PMID: 18050422 Free PMC article. Review.
The balance between CDK activation and inactivation determines whether cells proceed through G1 into S phase, and from G2 to M, through regulatory mechanisms that are conserved in more complex eukaryotes. ...
The balance between CDK activation and inactivation determines whether cells proceed through G1 into S phase, and from G2 to M, throu …
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