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Prospective evaluation of molecular screening for Lynch syndrome in patients with endometrial cancer ≤ 70 years.
Leenen CH, van Lier MG, van Doorn HC, van Leerdam ME, Kooi SG, de Waard J, Hoedemaeker RF, van den Ouweland AM, Hulspas SM, Dubbink HJ, Kuipers EJ, Wagner A, Dinjens WN, Steyerberg EW. Leenen CH, et al. Among authors: van leerdam me, van den ouweland am, van doorn hc, van lier mg. Gynecol Oncol. 2012 May;125(2):414-20. doi: 10.1016/j.ygyno.2012.01.049. Epub 2012 Feb 1. Gynecol Oncol. 2012. PMID: 22306203 Clinical Trial.
Yield of routine molecular analyses in colorectal cancer patients ≤70 years to detect underlying Lynch syndrome.
van Lier MG, Leenen CH, Wagner A, Ramsoekh D, Dubbink HJ, van den Ouweland AM, Westenend PJ, de Graaf EJ, Wolters LM, Vrijland WW, Kuipers EJ, van Leerdam ME, Steyerberg EW, Dinjens WN; LIMO Study Group. van Lier MG, et al. Among authors: van den ouweland am, van leerdam me. J Pathol. 2012 Apr;226(5):764-74. doi: 10.1002/path.3963. Epub 2012 Jan 17. J Pathol. 2012. PMID: 22081473
Somatic aberrations of mismatch repair genes as a cause of microsatellite-unstable cancers.
Geurts-Giele WR, Leenen CH, Dubbink HJ, Meijssen IC, Post E, Sleddens HF, Kuipers EJ, Goverde A, van den Ouweland AM, van Lier MG, Steyerberg EW, van Leerdam ME, Wagner A, Dinjens WN. Geurts-Giele WR, et al. Among authors: van den ouweland am, van leerdam me, van lier mg. J Pathol. 2014 Dec;234(4):548-59. doi: 10.1002/path.4419. Epub 2014 Sep 30. J Pathol. 2014. PMID: 25111426
Cost-effectiveness of routine screening for Lynch syndrome in colorectal cancer patients up to 70 years of age.
Leenen CH, Goverde A, de Bekker-Grob EW, Wagner A, van Lier MG, Spaander MC, Bruno MJ, Tops CM, van den Ouweland AM, Dubbink HJ, Kuipers EJ, Dinjens WN, van Leerdam ME, Steyerberg EW. Leenen CH, et al. Among authors: van den ouweland am, van leerdam me, van lier mg. Genet Med. 2016 Oct;18(10):966-73. doi: 10.1038/gim.2015.206. Epub 2016 Mar 3. Genet Med. 2016. PMID: 26938782 Free article.
Cost-effectiveness of routine screening for Lynch syndrome in endometrial cancer patients up to 70years of age.
Goverde A, Spaander MC, van Doorn HC, Dubbink HJ, van den Ouweland AM, Tops CM, Kooi SG, de Waard J, Hoedemaeker RF, Bruno MJ, Hofstra RM, de Bekker-Grob EW, Dinjens WN, Steyerberg EW, Wagner A; LIMO study group. Goverde A, et al. Among authors: van den ouweland am, van doorn hc. Gynecol Oncol. 2016 Dec;143(3):453-459. doi: 10.1016/j.ygyno.2016.10.008. Epub 2016 Oct 24. Gynecol Oncol. 2016. PMID: 27789085
Pitfalls in molecular analysis for mismatch repair deficiency in a family with biallelic pms2 germline mutations.
Leenen CH, Geurts-Giele WR, Dubbink HJ, Reddingius R, van den Ouweland AM, Tops CM, van de Klift HM, Kuipers EJ, van Leerdam ME, Dinjens WN, Wagner A. Leenen CH, et al. Among authors: van de klift hm, van den ouweland am, van leerdam me. Clin Genet. 2011 Dec;80(6):558-65. doi: 10.1111/j.1399-0004.2010.01608.x. Epub 2011 Jan 13. Clin Genet. 2011. PMID: 21204794
Functional analysis of MSH2 unclassified variants found in suspected Lynch syndrome patients reveals pathogenicity due to attenuated mismatch repair.
Wielders EA, Hettinger J, Dekker R, Kets CM, Ligtenberg MJ, Mensenkamp AR, van den Ouweland AM, Prins J, Wagner A, Dinjens WN, Dubbink HJ, van Hest LP, Menko F, Hogervorst F, Verhoef S, te Riele H. Wielders EA, et al. Among authors: van den ouweland am, van hest lp. J Med Genet. 2014 Apr;51(4):245-53. doi: 10.1136/jmedgenet-2013-101987. Epub 2014 Feb 5. J Med Genet. 2014. PMID: 24501230
278 results