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Curation and bioinformatic analysis of strabismus genes supports functional heterogeneity and proposes candidate genes with connections to RASopathies.
Ye XC, van der Lee R, Wasserman WW. Ye XC, et al. Among authors: van der lee r. Gene. 2019 May 20;697:213-226. doi: 10.1016/j.gene.2019.02.020. Epub 2019 Feb 15. Gene. 2019. PMID: 30772522
Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites.
Meerstein-Kessel L, van der Lee R, Stone W, Lanke K, Baker DA, Alano P, Silvestrini F, Janse CJ, Khan SM, van de Vegte-Bolmer M, Graumans W, Siebelink-Stoter R, Kooij TWA, Marti M, Drakeley C, Campo JJ, van Dam TJP, Sauerwein R, Bousema T, Huynen MA. Meerstein-Kessel L, et al. Among authors: van der lee r, van de vegte bolmer m, van dam tjp. Sci Rep. 2018 Jan 11;8(1):410. doi: 10.1038/s41598-017-18840-7. Sci Rep. 2018. PMID: 29323249 Free PMC article.
Intrinsically disordered segments affect protein half-life in the cell and during evolution.
van der Lee R, Lang B, Kruse K, Gsponer J, Sánchez de Groot N, Huynen MA, Matouschek A, Fuxreiter M, Babu MM. van der Lee R, et al. Cell Rep. 2014 Sep 25;8(6):1832-1844. doi: 10.1016/j.celrep.2014.07.055. Epub 2014 Sep 15. Cell Rep. 2014. PMID: 25220455 Free PMC article.
CiliaCarta: An integrated and validated compendium of ciliary genes.
van Dam TJP, Kennedy J, van der Lee R, de Vrieze E, Wunderlich KA, Rix S, Dougherty GW, Lambacher NJ, Li C, Jensen VL, Leroux MR, Hjeij R, Horn N, Texier Y, Wissinger Y, van Reeuwijk J, Wheway G, Knapp B, Scheel JF, Franco B, Mans DA, van Wijk E, Képès F, Slaats GG, Toedt G, Kremer H, Omran H, Szymanska K, Koutroumpas K, Ueffing M, Nguyen TT, Letteboer SJF, Oud MM, van Beersum SEC, Schmidts M, Beales PL, Lu Q, Giles RH, Szklarczyk R, Russell RB, Gibson TJ, Johnson CA, Blacque OE, Wolfrum U, Boldt K, Roepman R, Hernandez-Hernandez V, Huynen MA. van Dam TJP, et al. Among authors: van der lee r. PLoS One. 2019 May 16;14(5):e0216705. doi: 10.1371/journal.pone.0216705. eCollection 2019. PLoS One. 2019. PMID: 31095607 Free PMC article.
Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral Response.
van der Lee R, Feng Q, Langereis MA, Ter Horst R, Szklarczyk R, Netea MG, Andeweg AC, van Kuppeveld FJ, Huynen MA. van der Lee R, et al. Among authors: van kuppeveld fj. PLoS Comput Biol. 2015 Oct 20;11(10):e1004553. doi: 10.1371/journal.pcbi.1004553. eCollection 2015 Oct. PLoS Comput Biol. 2015. PMID: 26485378 Free PMC article.
Genome-scale detection of positive selection in nine primates predicts human-virus evolutionary conflicts.
van der Lee R, Wiel L, van Dam TJP, Huynen MA. van der Lee R, et al. Among authors: van dam tjp. Nucleic Acids Res. 2017 Oct 13;45(18):10634-10648. doi: 10.1093/nar/gkx704. Nucleic Acids Res. 2017. PMID: 28977405 Free PMC article.
Transcriptome analysis of complex I-deficient patients reveals distinct expression programs for subunits and assembly factors of the oxidative phosphorylation system.
van der Lee R, Szklarczyk R, Smeitink J, Smeets HJ, Huynen MA, Vogel R. van der Lee R, et al. BMC Genomics. 2015 Sep 15;16:691. doi: 10.1186/s12864-015-1883-8. BMC Genomics. 2015. PMID: 26369791 Free PMC article.
Intrinsically disordered proteins: regulation and disease.
Babu MM, van der Lee R, de Groot NS, Gsponer J. Babu MM, et al. Among authors: van der lee r. Curr Opin Struct Biol. 2011 Jun;21(3):432-40. doi: 10.1016/j.sbi.2011.03.011. Epub 2011 Apr 20. Curr Opin Struct Biol. 2011. PMID: 21514144 Review.
Classification of intrinsically disordered regions and proteins.
van der Lee R, Buljan M, Lang B, Weatheritt RJ, Daughdrill GW, Dunker AK, Fuxreiter M, Gough J, Gsponer J, Jones DT, Kim PM, Kriwacki RW, Oldfield CJ, Pappu RV, Tompa P, Uversky VN, Wright PE, Babu MM. van der Lee R, et al. Chem Rev. 2014 Jul 9;114(13):6589-631. doi: 10.1021/cr400525m. Epub 2014 Apr 29. Chem Rev. 2014. PMID: 24773235 Free PMC article. Review. No abstract available.
TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome.
Lambacher NJ, Bruel AL, van Dam TJ, Szymańska K, Slaats GG, Kuhns S, McManus GJ, Kennedy JE, Gaff K, Wu KM, van der Lee R, Burglen L, Doummar D, Rivière JB, Faivre L, Attié-Bitach T, Saunier S, Curd A, Peckham M, Giles RH, Johnson CA, Huynen MA, Thauvin-Robinet C, Blacque OE. Lambacher NJ, et al. Among authors: van dam tj, van der lee r. Nat Cell Biol. 2016 Jan;18(1):122-31. doi: 10.1038/ncb3273. Epub 2015 Nov 23. Nat Cell Biol. 2016. PMID: 26595381 Free PMC article.
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