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Mouse model systems to study multistep tumorigenesis.
Berns A, van der Lugt N, Alkema M, van Lohuizen M, Domen J, Acton D, Allen J, Laird PW, Jonkers J. Berns A, et al. Cold Spring Harb Symp Quant Biol. 1994;59:435-47. doi: 10.1101/sqb.1994.059.01.049. Cold Spring Harb Symp Quant Biol. 1994. PMID: 7587098 No abstract available.
A pgk::hprt fusion as a selectable marker for targeting of genes in mouse embryonic stem cells: disruption of the T-cell receptor delta-chain-encoding gene.
van der Lugt N, Maandag ER, te Riele H, Laird PW, Berns A. van der Lugt N, et al. Gene. 1991 Sep 15;105(2):263-7. doi: 10.1016/0378-1119(91)90161-4. Gene. 1991. PMID: 1834524
The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression.
van der Lugt NM, Alkema M, Berns A, Deschamps J. van der Lugt NM, et al. Mech Dev. 1996 Aug;58(1-2):153-64. doi: 10.1016/s0925-4773(96)00570-9. Mech Dev. 1996. PMID: 8887324
Directed expression of the growth-associated protein B-50/GAP-43 to olfactory neurons in transgenic mice results in changes in axon morphology and extraglomerular fiber growth.
Holtmaat AJ, Dijkhuizen PA, Oestreicher AB, Romijn HJ, Van der Lugt NM, Berns A, Margolis FL, Gispen WH, Verhaagen J. Holtmaat AJ, et al. J Neurosci. 1995 Dec;15(12):7953-65. doi: 10.1523/JNEUROSCI.15-12-07953.1995. J Neurosci. 1995. PMID: 8613733 Free PMC article.
Analysis of Pim-1 function in mutant mice.
Domen J, van der Lugt NM, Laird PW, Saris CJ, Berns A. Domen J, et al. Leukemia. 1993 Aug;7 Suppl 2:S108-12. Leukemia. 1993. PMID: 8361211
In vivo analysis of Pim-1 deficiency.
Laird PW, van der Lugt NM, Clarke A, Domen J, Linders K, McWhir J, Berns A, Hooper M. Laird PW, et al. Nucleic Acids Res. 1993 Oct 11;21(20):4750-5. doi: 10.1093/nar/21.20.4750. Nucleic Acids Res. 1993. PMID: 8233823 Free PMC article.
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.
van der Lugt NM, Domen J, Linders K, van Roon M, Robanus-Maandag E, te Riele H, van der Valk M, Deschamps J, Sofroniew M, van Lohuizen M, et al. van der Lugt NM, et al. Genes Dev. 1994 Apr 1;8(7):757-69. doi: 10.1101/gad.8.7.757. Genes Dev. 1994. PMID: 7926765
Pim-1 levels determine the size of early B lymphoid compartments in bone marrow.
Domen J, van der Lugt NM, Acton D, Laird PW, Linders K, Berns A. Domen J, et al. J Exp Med. 1993 Nov 1;178(5):1665-73. doi: 10.1084/jem.178.5.1665. J Exp Med. 1993. PMID: 8228813 Free PMC article.
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