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T-RMSD: a fine-grained, structure-based classification method and its application to the functional characterization of TNF receptors.
Magis C, Stricher F, van der Sloot AM, Serrano L, Notredame C. Magis C, et al. J Mol Biol. 2010 Jul 16;400(3):605-17. doi: 10.1016/j.jmb.2010.05.012. Epub 2010 May 13. J Mol Biol. 2010. PMID: 20471393
An improved understanding of TNFL/TNFR interactions using structure-based classifications.
Magis C, van der Sloot AM, Serrano L, Notredame C. Magis C, et al. Among authors: van der sloot am. Trends Biochem Sci. 2012 Sep;37(9):353-63. doi: 10.1016/j.tibs.2012.06.002. Epub 2012 Jul 11. Trends Biochem Sci. 2012. PMID: 22789664 Review.
Computational design of TNF ligand-based protein therapeutics.
van der Sloot AM, Quax WJ. van der Sloot AM, et al. Adv Exp Med Biol. 2011;691:521-34. doi: 10.1007/978-1-4419-6612-4_54. Adv Exp Med Biol. 2011. PMID: 21153357 Review. No abstract available.
Protein design in biological networks: from manipulating the input to modifying the output.
Van der Sloot AM, Kiel C, Serrano L, Stricher F. Van der Sloot AM, et al. Protein Eng Des Sel. 2009 Sep;22(9):537-42. doi: 10.1093/protein/gzp032. Epub 2009 Jul 2. Protein Eng Des Sel. 2009. PMID: 19574296 Review.
Building blocks for protein interaction devices.
Grünberg R, Ferrar TS, van der Sloot AM, Constante M, Serrano L. Grünberg R, et al. Nucleic Acids Res. 2010 May;38(8):2645-62. doi: 10.1093/nar/gkq152. Epub 2010 Mar 9. Nucleic Acids Res. 2010. PMID: 20215443 Free PMC article.
DR4-selective tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) variants obtained by structure-based design.
Tur V, van der Sloot AM, Reis CR, Szegezdi E, Cool RH, Samali A, Serrano L, Quax WJ. Tur V, et al. J Biol Chem. 2008 Jul 18;283(29):20560-8. doi: 10.1074/jbc.M800457200. Epub 2008 May 12. J Biol Chem. 2008. PMID: 18474604
Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity.
O'Leary L, van der Sloot AM, Reis CR, Deegan S, Ryan AE, Dhami SP, Murillo LS, Cool RH, Correa de Sampaio P, Thompson K, Murphy G, Quax WJ, Serrano L, Samali A, Szegezdi E. O'Leary L, et al. Among authors: van der sloot am. Oncogene. 2016 Mar 10;35(10):1261-70. doi: 10.1038/onc.2015.180. Epub 2015 Jun 8. Oncogene. 2016. PMID: 26050621
Protein design with fragment databases.
Verschueren E, Vanhee P, van der Sloot AM, Serrano L, Rousseau F, Schymkowitz J. Verschueren E, et al. Curr Opin Struct Biol. 2011 Aug;21(4):452-9. doi: 10.1016/ Epub 2011 Jun 16. Curr Opin Struct Biol. 2011. PMID: 21684149 Review.
Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity.
Carleton LA, Chakravarthy R, van der Sloot AM, Mnich K, Serrano L, Samali A, Gorman AM. Carleton LA, et al. Among authors: van der sloot am. Biochem Biophys Res Commun. 2018 Jan 1;495(1):700-705. doi: 10.1016/j.bbrc.2017.11.003. Epub 2017 Nov 3. Biochem Biophys Res Commun. 2018. PMID: 29108999
Engineering of weak helper interactions for high-efficiency FRET probes.
Grünberg R, Burnier JV, Ferrar T, Beltran-Sastre V, Stricher F, van der Sloot AM, Garcia-Olivas R, Mallabiabarrena A, Sanjuan X, Zimmermann T, Serrano L. Grünberg R, et al. Among authors: van der sloot am. Nat Methods. 2013 Oct;10(10):1021-7. doi: 10.1038/nmeth.2625. Epub 2013 Sep 1. Nat Methods. 2013. PMID: 23995386
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