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Mg2+ homeostasis: the balancing act of TRPM6.
van der Wijst J, Bindels RJ, Hoenderop JG. van der Wijst J, et al. Curr Opin Nephrol Hypertens. 2014 Jul;23(4):361-9. doi: 10.1097/01.mnh.0000447023.59346.ab. Curr Opin Nephrol Hypertens. 2014. PMID: 24906182 Review.
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
Groenestege WM, Thébault S, van der Wijst J, van den Berg D, Janssen R, Tejpar S, van den Heuvel LP, van Cutsem E, Hoenderop JG, Knoers NV, Bindels RJ. Groenestege WM, et al. J Clin Invest. 2007 Aug;117(8):2260-7. doi: 10.1172/JCI31680. J Clin Invest. 2007. PMID: 17671655 Free PMC article. Clinical Trial.
RACK1 inhibits TRPM6 activity via phosphorylation of the fused alpha-kinase domain.
Cao G, Thébault S, van der Wijst J, van der Kemp A, Lasonder E, Bindels RJ, Hoenderop JG. Cao G, et al. Curr Biol. 2008 Feb 12;18(3):168-76. doi: 10.1016/j.cub.2007.12.058. Curr Biol. 2008. PMID: 18258429
A missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia.
Glaudemans B, van der Wijst J, Scola RH, Lorenzoni PJ, Heister A, van der Kemp AW, Knoers NV, Hoenderop JG, Bindels RJ. Glaudemans B, et al. J Clin Invest. 2009 Apr;119(4):936-42. doi: 10.1172/JCI36948. Epub 2009 Mar 23. J Clin Invest. 2009. PMID: 19307729 Free PMC article.
Regulation of the epithelial Mg2+ channel TRPM6 by estrogen and the associated repressor protein of estrogen receptor activity (REA).
Cao G, van der Wijst J, van der Kemp A, van Zeeland F, Bindels RJ, Hoenderop JG. Cao G, et al. J Biol Chem. 2009 May 29;284(22):14788-95. doi: 10.1074/jbc.M808752200. Epub 2009 Mar 26. J Biol Chem. 2009. PMID: 19329436 Free PMC article.
Epithelial Mg2+ channel TRPM6: insight into the molecular regulation.
van der Wijst J, Hoenderop JG, Bindels RJ. van der Wijst J, et al. Magnes Res. 2009 Sep;22(3):127-32. Magnes Res. 2009. PMID: 19780399 Review.
Functional analysis of the Kv1.1 N255D mutation associated with autosomal dominant hypomagnesemia.
van der Wijst J, Glaudemans B, Venselaar H, Nair AV, Forst AL, Hoenderop JG, Bindels RJ. van der Wijst J, et al. J Biol Chem. 2010 Jan 1;285(1):171-8. doi: 10.1074/jbc.M109.041517. Epub 2009 Nov 10. J Biol Chem. 2010. PMID: 19903818 Free PMC article.
., van der Wijst, J., Scola, R. H., Lorenzoni, P. J., Heister, A., van der Kemp, A. W., Knoers, N. V., Hoenderop, J. G., and Bindels, R. J. (2009) J. Clin. Invest. 119, 936-942). A conserved asparagine at posit …
., van der Wijst, J., Scola, R. H., Lorenzoni, P. J., Heister, A., van der Kemp, A. W., Kno …
Methionine sulfoxide reductase B1 (MsrB1) recovers TRPM6 channel activity during oxidative stress.
Cao G, Lee KP, van der Wijst J, de Graaf M, van der Kemp A, Bindels RJ, Hoenderop JG. Cao G, et al. J Biol Chem. 2010 Aug 20;285(34):26081-7. doi: 10.1074/jbc.M110.103655. Epub 2010 Jun 28. J Biol Chem. 2010. PMID: 20584906 Free PMC article.
Effects of the EGFR Inhibitor Erlotinib on Magnesium Handling.
Dimke H, van der Wijst J, Alexander TR, Meijer IM, Mulder GM, van Goor H, Tejpar S, Hoenderop JG, Bindels RJ. Dimke H, et al. J Am Soc Nephrol. 2010 Aug;21(8):1309-16. doi: 10.1681/ASN.2009111153. Epub 2010 Jul 1. J Am Soc Nephrol. 2010. PMID: 20595681 Free PMC article.
New TRPM6 missense mutations linked to hypomagnesemia with secondary hypocalcemia.
Lainez S, Schlingmann KP, van der Wijst J, Dworniczak B, van Zeeland F, Konrad M, Bindels RJ, Hoenderop JG. Lainez S, et al. Eur J Hum Genet. 2014 Apr;22(4):497-504. doi: 10.1038/ejhg.2013.178. Epub 2013 Aug 14. Eur J Hum Genet. 2014. PMID: 23942199 Free PMC article.
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