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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2002 1
2004 1
2006 1
2007 2
2009 1
2010 1
2011 1
2013 2
2016 2
2019 1
2020 1
2026 0

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15 results

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Page 1
VEGF in Signaling and Disease: Beyond Discovery and Development.
Apte RS, Chen DS, Ferrara N. Apte RS, et al. Cell. 2019 Mar 7;176(6):1248-1264. doi: 10.1016/j.cell.2019.01.021. Cell. 2019. PMID: 30849371 Free PMC article. Review.
The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our understanding of vasculogenesis and angiogenesis during development and physiological homeostasis. ...It is also an elegant example of how ag …
The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our understa …
Vascular endothelial growth factor.
Ferrara N. Ferrara N. Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):789-91. doi: 10.1161/ATVBAHA.108.179663. Epub 2009 Jan 22. Arterioscler Thromb Vasc Biol. 2009. PMID: 19164810 Review.
Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. ...This brief review provides a historic account of the challenges associated with the discovery of VE …
Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathol …
Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover.
Street J, Bao M, deGuzman L, Bunting S, Peale FV Jr, Ferrara N, Steinmetz H, Hoeffel J, Cleland JL, Daugherty A, van Bruggen N, Redmond HP, Carano RA, Filvaroff EH. Street J, et al. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9656-61. doi: 10.1073/pnas.152324099. Epub 2002 Jul 12. Proc Natl Acad Sci U S A. 2002. PMID: 12118119 Free PMC article.
Several growth factors are expressed in distinct temporal and spatial patterns during fracture repair. Of these, vascular endothelial growth factor, VEGF, is of particular interest because of its ability to induce neovascularizatio …
Several growth factors are expressed in distinct temporal and spatial patterns during fracture repair. Of these, vascular …
Imaging tumor angiogenesis.
Red-Horse K, Ferrara N. Red-Horse K, et al. J Clin Invest. 2006 Oct;116(10):2585-7. doi: 10.1172/JCI30058. J Clin Invest. 2006. PMID: 17016553 Free PMC article.
Since the discovery of vascular-specific growth factors with angiogenic activity, there has been a significant effort to develop cancer drugs that restrict tumorigenesis by targeting the blood supply. ...
Since the discovery of vascular-specific growth factors with angiogenic activity, there has been a significant e …
From the discovery of vascular endothelial growth factor to the introduction of avastin in clinical trials - an interview with Napoleone Ferrara by Domenico Ribatti.
Ferrara N. Ferrara N. Int J Dev Biol. 2011;55(4-5):383-8. doi: 10.1387/ijdb.103216dr. Int J Dev Biol. 2011. PMID: 21858763 Free article.
Napoleone Ferrara and his colleagues at Genentech were the first to isolate and clone vascular endothelial growth factor (VEGF) in 1989. His laboratory has investigated many aspects of VEGF biochemistry and molecular biology. In 19 …
Napoleone Ferrara and his colleagues at Genentech were the first to isolate and clone vascular endothelial growth …
Ten years of anti-vascular endothelial growth factor therapy.
Ferrara N, Adamis AP. Ferrara N, et al. Nat Rev Drug Discov. 2016 Jun;15(6):385-403. doi: 10.1038/nrd.2015.17. Epub 2016 Jan 18. Nat Rev Drug Discov. 2016. PMID: 26775688 Free article.
The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both normal and pathological angiogenesis, has revealed innovative therapeutic approaches in oncology and ophthalmology. ...To mark this tenth anniversa …
The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both normal and pat …
VEGF: From Discovery to Therapy: The Champalimaud Award Lecture.
Miller JW. Miller JW. Transl Vis Sci Technol. 2016 Mar 11;5(2):9. doi: 10.1167/tvst.5.2.9. eCollection 2016 Mar. Transl Vis Sci Technol. 2016. PMID: 26981331 Free PMC article.
PURPOSE: Intraocular vascular diseases are leading causes of adult vision loss, and in the mid-1900s, I. C. Michaelson postulated that the retina releases a soluble, diffusible factor that causes abnormal vascular growth and leakage. ...Recognizing tha …
PURPOSE: Intraocular vascular diseases are leading causes of adult vision loss, and in the mid-1900s, I. C. Michaelson postulated tha …
Clinical application of therapies targeting VEGF.
Yancopoulos GD. Yancopoulos GD. Cell. 2010 Oct 1;143(1):13-6. doi: 10.1016/j.cell.2010.09.028. Cell. 2010. PMID: 20887885 Free article.
This year's Lasker DeBakey Clinical Research Award goes to Napoleone Ferrara for the discovery of vascular endothelial growth factor (VEGF) as a major mediator of angiogenesis and for the development of an effective anti- …
This year's Lasker DeBakey Clinical Research Award goes to Napoleone Ferrara for the discovery of vascular endotheli …
Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer.
Pichler M, Rodriguez-Aguayo C, Nam SY, Dragomir MP, Bayraktar R, Anfossi S, Knutsen E, Ivan C, Fuentes-Mattei E, Lee SK, Ling H, Catela Ivkovic T, Huang G, Huang L, Okugawa Y, Katayama H, Taguchi A, Bayraktar E, Bhattacharya R, Amero P, He WR, Tran AM, Vychytilova-Faltejskova P, Klec C, Bonilla DL, Zhang X, Kapitanovic S, Loncar B, Gafà R, Wang Z, Cristini V, Hanash SM, Bar-Eli M, Lanza G, Slaby O, Goel A, Rigoutsos I, Lopez-Berestein G, Calin GA. Pichler M, et al. Gut. 2020 Oct;69(10):1818-1831. doi: 10.1136/gutjnl-2019-318903. Epub 2020 Jan 27. Gut. 2020. PMID: 31988194 Free PMC article.
Both in vitro and in vivo experiments demonstrated that the modulation of FLANC expression influenced cellular growth, apoptosis, migration, angiogenesis and metastases formation ability of CRC cells. ...Mechanistically, FLANC upregulated and prolonged the half-life …
Both in vitro and in vivo experiments demonstrated that the modulation of FLANC expression influenced cellular growth, apoptosis, mig …
15 results