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CD4⁺ CD28^null T cells are not alloreactive unless stimulated by interleukin-15.

Dedeoglu B, Litjens NHR, Klepper M, Kraaijeveld R, Verschoor W, Baan CC, Betjes MGH. Dedeoglu B, et al. Among authors: verschoor w. Am J Transplant. 2018 Feb;18(2):341-350. doi: 10.1111/ajt.14480. Epub 2017 Oct 2. Am J Transplant. 2018. PMID: 28858434 Free article.

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Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation.

de Graav GN, Hesselink DA, Dieterich M, Kraaijeveld R, Verschoor W, Roelen DL, Litjens NHR, Chong AS, Weimar W, Baan CC. de Graav GN, et al. Among authors: verschoor w. Front Immunol. 2017 May 31;8:641. doi: 10.3389/fimmu.2017.00641. eCollection 2017. Front Immunol. 2017. PMID: 28620390 Free PMC article.

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A Randomized Controlled Clinical Trial Comparing Belatacept With Tacrolimus After De Novo Kidney Transplantation.

de Graav GN, Baan CC, Clahsen-van Groningen MC, Kraaijeveld R, Dieterich M, Verschoor W, von der Thusen JH, Roelen DL, Cadogan M, van de Wetering J, van Rosmalen J, Weimar W, Hesselink DA. de Graav GN, et al. Among authors: verschoor w. Transplantation. 2017 Oct;101(10):2571-2581. doi: 10.1097/TP.0000000000001755. Transplantation. 2017. PMID: 28403127 Clinical Trial.

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Allogeneic Mature Human Dendritic Cells Generate Superior Alloreactive Regulatory T Cells in the Presence of IL-15.

Litjens NH, Boer K, Zuijderwijk JM, Klepper M, Peeters AM, Prens EP, Verschoor W, Kraaijeveld R, Ozgur Z, van den Hout-van Vroonhoven MC, van IJcken WF, Baan CC, Betjes MG. Litjens NH, et al. Among authors: verschoor w. J Immunol. 2015 Jun 1;194(11):5282-93. doi: 10.4049/jimmunol.1402827. Epub 2015 Apr 27. J Immunol. 2015. PMID: 25917092 Free article.

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Lymph node and circulating T cell characteristics are strongly correlated in end-stage renal disease patients, but highly differentiated T cells reside within the circulation.

Dedeoglu B, de Weerd AE, Huang L, Langerak AW, Dor FJ, Klepper M, Verschoor W, Reijerkerk D, Baan CC, Litjens NH, Betjes MG. Dedeoglu B, et al. Among authors: verschoor w. Clin Exp Immunol. 2017 May;188(2):299-310. doi: 10.1111/cei.12934. Epub 2017 Feb 28. Clin Exp Immunol. 2017. PMID: 28142201 Free PMC article.

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End-stage renal failure and regulatory activities of CD4+CD25bright+FoxP3+ T-cells.

Hendrikx TK, van Gurp EA, Mol WM, Schoordijk W, Sewgobind VD, Ijzermans JN, Weimar W, Baan CC. Hendrikx TK, et al. Among authors: schoordijk w. Nephrol Dial Transplant. 2009 Jun;24(6):1969-78. doi: 10.1093/ndt/gfp005. Epub 2009 Feb 4. Nephrol Dial Transplant. 2009. PMID: 19193737

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Natural regulatory T cells from patients with end-stage renal disease can be used for large-scale generation of highly suppressive alloantigen-specific Tregs.

Litjens NH, Boer K, Zuijderwijk JM, Klepper M, Peeters AM, Verschoor W, Kraaijeveld R, Betjes MG. Litjens NH, et al. Among authors: verschoor w. Kidney Int. 2017 May;91(5):1203-1213. doi: 10.1016/j.kint.2016.09.043. Epub 2016 Dec 15. Kidney Int. 2017. PMID: 27988212

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Generation of donor-specific regulatory T-cell function in kidney transplant patients.

Hendrikx TK, van Gurp EA, Sewgobind VD, Mol WM, Schoordijk W, Klepper M, Velthuis JH, Geel A, Ijzermans JN, Weimar W, Baan CC. Hendrikx TK, et al. Among authors: schoordijk w. Transplantation. 2009 Feb 15;87(3):376-83. doi: 10.1097/TP.0b013e3181901b69. Transplantation. 2009. PMID: 19202442

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The effects of renal transplantation on circulating dendritic cells.

Hesselink DA, Vaessen LM, Hop WC, Schoordijk W, Ijzermans JN, Baan CC, Weimar W. Hesselink DA, et al. Among authors: schoordijk w. Clin Exp Immunol. 2005 May;140(2):384-93. doi: 10.1111/j.1365-2249.2005.02755.x. Clin Exp Immunol. 2005. PMID: 15807866 Free PMC article.

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Monotherapy rapamycin allows an increase of CD4 CD25 FoxP3 T cells in renal recipients.

Hendrikx TK, Velthuis JH, Klepper M, van Gurp E, Geel A, Schoordijk W, Baan CC, Weimar W. Hendrikx TK, et al. Among authors: schoordijk w. Transpl Int. 2009 Sep;22(9):884-91. doi: 10.1111/j.1432-2277.2009.00890.x. Epub 2009 May 5. Transpl Int. 2009. PMID: 19453998 Free article.

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