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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
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35 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Vinpocetine, cognition, and epilepsy.
Meador KJ, Leeman-Markowski B, Medina AE, Illamola SM, Seliger J, Novak G, Lin C, Ivanisevic M, Razavi B, Marino S, Boyd A, Loring DW. Meador KJ, et al. Epilepsy Behav. 2021 Jun;119:107988. doi: 10.1016/j.yebeh.2021.107988. Epub 2021 May 3. Epilepsy Behav. 2021. PMID: 33957389 Clinical Trial.
No appreciable side effects occurred. Vinpocetine and AVA levels were lower in humans than animals. CONCLUSIONS: Vinpocetine was well tolerated, but was not associated with positive cognitive effects. ...This suggests that higher dosages are needed in humans to asse …
No appreciable side effects occurred. Vinpocetine and AVA levels were lower in humans than animals. CONCLUSIONS: Vinpocetine w …
Vinpocetine for cognitive impairment and dementia.
Szatmari SZ, Whitehouse PJ. Szatmari SZ, et al. Cochrane Database Syst Rev. 2003;2003(1):CD003119. doi: 10.1002/14651858.CD003119. Cochrane Database Syst Rev. 2003. PMID: 12535455 Free PMC article.
BACKGROUND: Vinpocetine is a synthetic ethyl ester of apovincamine, a vinca alkaloid obtained from the leaves of the Lesser Periwinkle (Vinca minor) and discovered in the late 1960s. ...The manufacturers of vinpocetine were asked for information on trials of vinp …
BACKGROUND: Vinpocetine is a synthetic ethyl ester of apovincamine, a vinca alkaloid obtained from the leaves of the Lesser Periwinkl …
Safety and Efficacy of Vinpocetine as a Neuroprotective Agent in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.
Panda PK, Ramachandran A, Panda P, Sharawat IK. Panda PK, et al. Neurocrit Care. 2022 Aug;37(1):314-325. doi: 10.1007/s12028-022-01499-y. Epub 2022 Apr 29. Neurocrit Care. 2022. PMID: 35488169 Free PMC article.
BACKGROUND: Vinpocetine as a neuroprotective agent is effective in acute ischemic stroke in some randomized controlled trials (RCTs). ...RESULTS: Four placebo-controlled RCTs enrolling a total of 601 and 236 patients in vinpocetine and placebo groups, respectively, …
BACKGROUND: Vinpocetine as a neuroprotective agent is effective in acute ischemic stroke in some randomized controlled trials (RCTs). …
Extended-release vinpocetine: a possible adjuvant treatment for focal onset epileptic seizures.
Garza-Morales S, Briceño-González E, Ceja-Moreno H, Ruiz-Sandoval JL, Góngora-Rivera F, Rodríguez-Leyva I, Alonso-Rivera CG. Garza-Morales S, et al. Bol Med Hosp Infant Mex. 2019;76(5):215-224. doi: 10.24875/BMHIM.19000056. Bol Med Hosp Infant Mex. 2019. PMID: 31536041 Clinical Trial. English.
No significant differences in the presence of adverse effects in patients treated with vinpocetine compared to those treated with placebo were observed. The most frequent adverse events observed with vinpocetine were headache (7.9%) and diplopia (5.2%). ...Vinpoc …
No significant differences in the presence of adverse effects in patients treated with vinpocetine compared to those treated with pla …
[The role of vinpocetine in the treatment of cerebrovascular diseases based in human studies].
Bagoly E, Fehér G, Szapáry L. Bagoly E, et al. Orv Hetil. 2007 Jul 22;148(29):1353-8. doi: 10.1556/OH.2007.28115. Orv Hetil. 2007. PMID: 17631470 Hungarian.
METHODS: The aim of this review was to summarize the indications and the potential effects of vinpocetine in acute and chronic cerebrovascular diseases based on clinical studies. RESULTS: There is no evidence that vinpocetine treatment is applicable in acute ischemi …
METHODS: The aim of this review was to summarize the indications and the potential effects of vinpocetine in acute and chronic cerebr …
Combination of Vinpocetine and Dexamethasone Alleviates Cognitive Impairment in Nasopharyngeal Carcinoma Patients following Radiation Injury.
Zhang P, Cao Y, Chen S, Shao L. Zhang P, et al. Pharmacology. 2021;106(1-2):37-44. doi: 10.1159/000506777. Epub 2020 Apr 15. Pharmacology. 2021. PMID: 32294652 Clinical Trial.
Principally, toll-like receptors (TLRs) could regulate the inflammatory/anti-inflammatory balance in patients with radiation-induced brain injury. Vinpocetine has an anti-inflammatory effect as shown in both animal and in vitro studies. ...Thus, it is important to test whe …
Principally, toll-like receptors (TLRs) could regulate the inflammatory/anti-inflammatory balance in patients with radiation-induced brain i …
The treatment of cognitive dysfunction in dementia: a multiple treatments meta-analysis.
Perng CH, Chang YC, Tzang RF. Perng CH, et al. Psychopharmacology (Berl). 2018 May;235(5):1571-1580. doi: 10.1007/s00213-018-4867-y. Epub 2018 Mar 3. Psychopharmacology (Berl). 2018. PMID: 29502274

The results of meta-regression showed that in young patients (beta = - 0.036, p value < 0.001) with vascular dementia (beta = 0.603, p value < 0.001), the efficacies of treatment 2 (symptomatic treatment for vascular dementia with piracetam, nimodipine, aniracetam, flunariz

…

The results of meta-regression showed that in young patients (beta = - 0.036, p value < 0.001) with vascular dementia (beta = 0.603, p va

…
Vinpocetine treatment in acute ischaemic stroke: a pilot single-blind randomized clinical trial.
Feigin VL, Doronin BM, Popova TF, Gribatcheva EV, Tchervov DV. Feigin VL, et al. Eur J Neurol. 2001 Jan;8(1):81-5. doi: 10.1046/j.1468-1331.2001.00181.x. Eur J Neurol. 2001. PMID: 11509086 Clinical Trial.

The patients were randomly allocated to receive either low-molecular weight dextran alone or in combination with vinpocetine. Poor outcome was defined as being dead or having a Barthel index of < 70 or a Rankin score of 3--5. ...This pilot study shows that a full-scale

…
The patients were randomly allocated to receive either low-molecular weight dextran alone or in combination with vinpocetine. Poor ou …
Lack of pharmacokinetic interaction between vinpocetine and oxazepam.
Storm G, Oosterhuis B, Sollie FA, Visscher HW, Sommer W, Beitinger H, Jonkman JH. Storm G, et al. Br J Clin Pharmacol. 1994 Aug;38(2):143-6. doi: 10.1111/j.1365-2125.1994.tb04338.x. Br J Clin Pharmacol. 1994. PMID: 7981015 Free PMC article. Clinical Trial.
The influence of multiple doses of vinpocetine (10 mg three times daily) on the steady state plasma concentrations of oxazepam (10 mg three times daily) was studied in 16 healthy subjects. ...The results indicate a lack of influence of vinpocetine on oxazepam kineti …
The influence of multiple doses of vinpocetine (10 mg three times daily) on the steady state plasma concentrations of oxazepam (10 mg …
Psychopharmacological effects of vinpocetine in normal healthy volunteers.
Subhan Z, Hindmarch I. Subhan Z, et al. Eur J Clin Pharmacol. 1985;28(5):567-71. doi: 10.1007/BF00544068. Eur J Clin Pharmacol. 1985. PMID: 3899677 Clinical Trial.
Twelve healthy female volunteers received pre-treatments with vinpocetine 10, 20, 40 mg and placebo (t.d.s.) for two days according to a randomised, double-blind crossover design. ...However, memory as assessed using the Sternberg technique was found to be significantly im …
Twelve healthy female volunteers received pre-treatments with vinpocetine 10, 20, 40 mg and placebo (t.d.s.) for two days according t …
35 results