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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1940 1
1945 5
1946 17
1947 16
1948 19
1949 27
1950 43
1951 33
1952 48
1953 53
1954 57
1955 46
1956 49
1957 39
1958 38
1959 50
1960 47
1961 34
1962 53
1963 111
1964 140
1965 96
1966 103
1967 144
1968 160
1969 203
1970 172
1971 197
1972 166
1973 141
1974 191
1975 144
1976 96
1977 109
1978 95
1979 105
1980 110
1981 118
1982 132
1983 147
1984 173
1985 173
1986 162
1987 183
1988 174
1989 207
1990 197
1991 249
1992 245
1993 269
1994 311
1995 373
1996 375
1997 421
1998 462
1999 537
2000 633
2001 658
2002 648
2003 708
2004 740
2005 785
2006 803
2007 832
2008 872
2009 907
2010 1027
2011 1107
2012 1180
2013 1256
2014 1381
2015 1430
2016 1350
2017 1372
2018 1438
2019 1415
2020 1503
2021 825
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Vitamin D and Cardiovascular Disease: Controversy Unresolved.
Al Mheid I, Quyyumi AA. Al Mheid I, et al. J Am Coll Cardiol. 2017 Jul 4;70(1):89-100. doi: 10.1016/j.jacc.2017.05.031. J Am Coll Cardiol. 2017. PMID: 28662812 Free article. Review.
Serum levels of 25-hydroxyvitamin D l <20 ng/ml are diagnostic of vitamin D deficiency. Vitamin D has various cardiovascular pleiotropic effects by activating its nuclear receptor in cardiomyocytes and vascular endothelial cells and by regulating the renin …
Serum levels of 25-hydroxyvitamin D l <20 ng/ml are diagnostic of vitamin D deficiency. Vitamin D has various cardiovasc …
Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer: An updated systematic evidence review for the U.S. Preventive Services Task Force.
Fortmann SP, Burda BU, Senger CA, Lin JS, Whitlock EP. Fortmann SP, et al. Ann Intern Med. 2013 Dec 17;159(12):824-34. doi: 10.7326/0003-4819-159-12-201312170-00729. Ann Intern Med. 2013. PMID: 24217421 Free article. Review.
BACKGROUND: Vitamin and mineral supplements are commonly used to prevent chronic diseases. PURPOSE: To systematically review evidence for the benefit and harms of vitamin and mineral supplements in community-dwelling, nutrient-sufficient adults for the primary preve …
BACKGROUND: Vitamin and mineral supplements are commonly used to prevent chronic diseases. PURPOSE: To systematically review evidence …
Vitamin D and cardiovascular disease: From atherosclerosis to myocardial infarction and stroke.
Muscogiuri G, Annweiler C, Duval G, Karras S, Tirabassi G, Salvio G, Balercia G, Kimball S, Kotsa K, Mascitelli L, Bhattoa HP, Colao A. Muscogiuri G, et al. Int J Cardiol. 2017 Mar 1;230:577-584. doi: 10.1016/j.ijcard.2016.12.053. Epub 2016 Dec 26. Int J Cardiol. 2017. PMID: 28043680 Review.
There continues to be interest in understanding the role of vitamin D in the pathogenesis, epidemiology and prevention of cardiovascular disease (CVD). ...Thus, the goal of this review is to provide an updated review of the literature on the basic science of how …
There continues to be interest in understanding the role of vitamin D in the pathogenesis, epidemiology and prevention of cardiova …
Vitamin D status and cardiovascular outcome.
Saponaro F, Marcocci C, Zucchi R. Saponaro F, et al. J Endocrinol Invest. 2019 Nov;42(11):1285-1290. doi: 10.1007/s40618-019-01057-y. Epub 2019 Jun 6. J Endocrinol Invest. 2019. PMID: 31172459 Review.
INTRODUCTION: Vitamin D is classically involved in maintaining bone and mineral health, but it has been shown to exert many extraskeletal functions, including pleiotropic effects on cardiovascular system. MATERIALS AND METHOD: This review aims to summarize ev …
INTRODUCTION: Vitamin D is classically involved in maintaining bone and mineral health, but it has been shown to exert many extraskel …
Vitamin D and the Skin: An Update for Dermatologists.
Kechichian E, Ezzedine K. Kechichian E, et al. Am J Clin Dermatol. 2018 Apr;19(2):223-235. doi: 10.1007/s40257-017-0323-8. Am J Clin Dermatol. 2018. PMID: 28994020 Review.
Vitamin D plays a key role in skeletal and cardiovascular disorders, cancers, central nervous system diseases, reproductive diseases, infections, and autoimmune and dermatological disorders. The two main sources of vitamin D are sun exposure and oral i …
Vitamin D plays a key role in skeletal and cardiovascular disorders, cancers, central nervous system diseases, reproduc …
Cardiovascular Diseases and Fat Soluble Vitamins: Vitamin D and Vitamin K.
Tsugawa N. Tsugawa N. J Nutr Sci Vitaminol (Tokyo). 2015;61 Suppl:S170-2. doi: 10.3177/jnsv.61.S170. J Nutr Sci Vitaminol (Tokyo). 2015. PMID: 26598844 Free article. Review.
Recently, the associations between insufficiency of fat soluble vitamins and cardiovascular diseases (CVDs) have been reported. Vitamin D affects the cardiovascular system via several pathways, such as suppression of parathyroid hormone, the ren …
Recently, the associations between insufficiency of fat soluble vitamins and cardiovascular diseases (CVDs) have been reported …
Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment.
Sunkara A, Raizner A. Sunkara A, et al. Methodist Debakey Cardiovasc J. 2019 Jul-Sep;15(3):179-184. doi: 10.14797/mdcj-15-3-179. Methodist Debakey Cardiovasc J. 2019. PMID: 31687096 Free PMC article. Review.
Vitamins and minerals are dietary supplements used by almost half of the US adult population based on the presumption that they help prevent or treat cardiovascular disease. ...Despite extensive investigation, the evidence to date fails to support the use of exogeno …
Vitamins and minerals are dietary supplements used by almost half of the US adult population based on the presumption that they help …
Thiamine and Cardiovascular Disease: A Literature Review.
DiNicolantonio JJ, Liu J, O'Keefe JH. DiNicolantonio JJ, et al. Prog Cardiovasc Dis. 2018 May-Jun;61(1):27-32. doi: 10.1016/j.pcad.2018.01.009. Epub 2018 Jan 31. Prog Cardiovasc Dis. 2018. PMID: 29360523 Review.
Thiamine is a water-soluble vitamin that plays an important role in the energy metabolism in the human body. ...This article aims to provide a review of current literature on the role of thiamine in the human body, the current scope of thiamine deficiency, and explore the …
Thiamine is a water-soluble vitamin that plays an important role in the energy metabolism in the human body. ...This article aims to …
Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials.
Myung SK, Ju W, Cho B, Oh SW, Park SM, Koo BK, Park BJ; Korean Meta-Analysis Study Group. Myung SK, et al. BMJ. 2013 Jan 18;346:f10. doi: 10.1136/bmj.f10. BMJ. 2013. PMID: 23335472 Free PMC article. Review.
OBJECTIVE: To assess the efficacy of vitamin and antioxidant supplements in the prevention of cardiovascular diseases. ...CONCLUSION: There is no evidence to support the use of vitamin and antioxidant supplements for prevention of cardiovascular diseas …
OBJECTIVE: To assess the efficacy of vitamin and antioxidant supplements in the prevention of cardiovascular diseases. ...CONC …
Vitamin D and Cardiovascular Disease.
Schwarz N, Nicholls SJ, Psaltis PJ. Schwarz N, et al. Heart Lung Circ. 2018 Aug;27(8):903-906. doi: 10.1016/j.hlc.2018.05.098. Heart Lung Circ. 2018. PMID: 30047471 No abstract available.
Vitamin D and colorectal cancer: molecular, epidemiological and clinical evidence.
Dou R, Ng K, Giovannucci EL, Manson JE, Qian ZR, Ogino S. Dou R, et al. Br J Nutr. 2016 May;115(9):1643-60. doi: 10.1017/S0007114516000696. Br J Nutr. 2016. PMID: 27245104 Free PMC article. Review.
In many cells throughout the body, vitamin D is converted into its active form calcitriol and binds to the vitamin D receptor (VDR), which functions as a transcription factor to regulate various biological processes including cellular differentiation and immune resp …
In many cells throughout the body, vitamin D is converted into its active form calcitriol and binds to the vitamin D receptor …
Limited evidence for a beneficial effect of vitamin C supplementation on biomarkers of cardiovascular diseases: an umbrella review of systematic reviews and meta-analyses.
Ashor AW, Brown R, Keenan PD, Willis ND, Siervo M, Mathers JC. Ashor AW, et al. Nutr Res. 2019 Jan;61:1-12. doi: 10.1016/j.nutres.2018.08.005. Epub 2018 Sep 1. Nutr Res. 2019. PMID: 30683434 Review.
Vitamin C is an essential nutrient with important antioxidant properties. Higher vitamin C intake appears to be associated with positive effects on cardiovascular risk factors in cohort studies, whereas large randomized controlled clinical trials did not conf …
Vitamin C is an essential nutrient with important antioxidant properties. Higher vitamin C intake appears to be associated wit …
Vitamin D and cardiovascular disease: is the evidence solid?
Al Mheid I, Patel RS, Tangpricha V, Quyyumi AA. Al Mheid I, et al. Eur Heart J. 2013 Dec;34(48):3691-8. doi: 10.1093/eurheartj/eht166. Epub 2013 Jun 9. Eur Heart J. 2013. PMID: 23751422 Free PMC article. Review.
While the endocrine functions of vitamin D related to bone metabolism and mineral ion homoeostasis have been extensively studied, robust epidemiological evidence also suggests a close association between vitamin D deficiency and cardiovascular morbidity and m …
While the endocrine functions of vitamin D related to bone metabolism and mineral ion homoeostasis have been extensively studied, rob …
Vitamin D in the Spectrum of Prediabetes and Cardiovascular Autonomic Dysfunction.
Dimova R, Tankova T, Chakarova N. Dimova R, et al. J Nutr. 2017 Sep;147(9):1607-1615. doi: 10.3945/jn.117.250209. Epub 2017 Aug 2. J Nutr. 2017. PMID: 28768837 Review.
Vitamin D is a fat-soluble secosteroid hormone with pleiotropic effects. 1,25-Dihydroxyvitamin D coordinates the biosynthesis of neurotransmitters in the central nervous system, which regulate cardiovascular autonomic function and may explain its putative rol …
Vitamin D is a fat-soluble secosteroid hormone with pleiotropic effects. 1,25-Dihydroxyvitamin D coordinates the biosynthesis of neur …
Vitamin E and cardiovascular disease.
Saremi A, Arora R. Saremi A, et al. Am J Ther. 2010 May-Jun;17(3):e56-65. doi: 10.1097/MJT.0b013e31819cdc9a. Am J Ther. 2010. PMID: 19451807 Review.
The objective of this article is to review the role of vitamin E in cardiovascular disease. We begin by describing the general characteristics and metabolism of vitamin E and the pathogenesis of atherosclerosis as it relates to oxidation. ...The American Hear …
The objective of this article is to review the role of vitamin E in cardiovascular disease. We begin by describing the general …
Vitamin D and cardiovascular prevention.
Nadir MA, Szwejkowski BR, Witham MD. Nadir MA, et al. Cardiovasc Ther. 2010 Aug;28(4):e5-12. doi: 10.1111/j.1755-5922.2010.00192.x. Epub 2010 Jun 11. Cardiovasc Ther. 2010. PMID: 20553279 Free article. Review.
Interventional studies are beginning to explore whether vitamin D supplementation can modify vascular health and prevent cardiovascular disease. This article reviews the physiology and function of vitamin D, examines the current observational and intervention …
Interventional studies are beginning to explore whether vitamin D supplementation can modify vascular health and prevent cardiovas …
Vitamin K effects in human health: new insights beyond bone and cardiovascular health.
Fusaro M, Gallieni M, Porta C, Nickolas TL, Khairallah P. Fusaro M, et al. J Nephrol. 2020 Apr;33(2):239-249. doi: 10.1007/s40620-019-00685-0. Epub 2019 Dec 19. J Nephrol. 2020. PMID: 31858448 Free article. Review.
Vitamin K is a cofactor for the function of the enzyme gamma-glutamyl carboxylase, necessary for the activation of multiple vitamin K dependent-proteins. ...This review discusses vitamin K status in human health and the physiologic and pathologic roles of VKD …
Vitamin K is a cofactor for the function of the enzyme gamma-glutamyl carboxylase, necessary for the activation of multiple vitami …
Vitamin D and cardiovascular disease: potential role in health disparities.
Artaza JN, Contreras S, Garcia LA, Mehrotra R, Gibbons G, Shohet R, Martins D, Norris KC. Artaza JN, et al. J Health Care Poor Underserved. 2011;22(4 Suppl):23-38. doi: 10.1353/hpu.2011.0161. J Health Care Poor Underserved. 2011. PMID: 22102304 Free PMC article. Review.
Cardiovascular disease (CVD), which includes coronary artery disease and stroke, is the leading cause of mortality in the nation. ...We review the epidemiology of vitamin D and CVD in African Americans and the emerging biological roles of vitamin D in key CVD …
Cardiovascular disease (CVD), which includes coronary artery disease and stroke, is the leading cause of mortality in the nation. ... …
Vitamin D, Calcium, and Cardiovascular Disease: A"D"vantageous or "D"etrimental? An Era of Uncertainty.
Chin K, Appel LJ, Michos ED. Chin K, et al. Curr Atheroscler Rep. 2017 Jan;19(1):5. doi: 10.1007/s11883-017-0637-2. Curr Atheroscler Rep. 2017. PMID: 28127710 Free PMC article. Review.
While the function of vitamin D in regulating calcium homeostasis is well established, there has been growing interest in its role in the prevention of numerous chronic diseases, including cardiovascular disease (CVD). There is mounting epidemiological evidence sugg …
While the function of vitamin D in regulating calcium homeostasis is well established, there has been growing interest in its role in …
The role of vitamin D in dyslipidemia and cardiovascular disease.
Zittermann A, Gummert JF, Börgermann J. Zittermann A, et al. Curr Pharm Des. 2011;17(9):933-42. doi: 10.2174/138161211795428786. Curr Pharm Des. 2011. PMID: 21418036 Review.
Dyslipidemia and vascular calcification are important predictors of cardiovascular disease (CVD). Vitamin D may have an influence on these two CVD risk markers. ...The previously presumed influence of statins on circulating 25-hydroxyvitamin D levels and on cellular …
Dyslipidemia and vascular calcification are important predictors of cardiovascular disease (CVD). Vitamin D may have an influe …
The Physiological/Pathophysiological Significance of Vitamin D in Cancer, Cardiovascular Disorders and Beyond.
AlMatar M, AlMandeal H, Makky EA, Kayar B, Yarar E, Var I, Koksal F. AlMatar M, et al. Curr Drug Metab. 2017;18(3):207-224. doi: 10.2174/1389200217666161207161212. Curr Drug Metab. 2017. PMID: 27928943 Review.
Moreover, recent reports revealed that the effect of vitamin D is to cover not only cardiovascular system but also skeletal system. OBJECTIVE: Herein, we are highlighting the recent knowledge of vitamin D roles and functions with respect to path …
Moreover, recent reports revealed that the effect of vitamin D is to cover not only cardiovascular system but also skel …
[Vitamin D deficiency and cardiovascular diseases].
Mascitelli L, Goldstein MR, Pezzetta F. Mascitelli L, et al. Recenti Prog Med. 2010 May;101(5):202-11. Recenti Prog Med. 2010. PMID: 20590017 Review. Italian.
However, it has become evident that adequate vitamin D status is important for optimal function of many organs and tissues throughout the body, including the cardiovascular system. ...The relationship between baseline vitamin D status, dose of vitam …
However, it has become evident that adequate vitamin D status is important for optimal function of many organs and tissues throughout …
The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature.
Papandreou D, Hamid ZT. Papandreou D, et al. Dis Markers. 2015;2015:580474. doi: 10.1155/2015/580474. Epub 2015 Oct 20. Dis Markers. 2015. PMID: 26576069 Free PMC article. Review.
The dietary reference values for Vitamin D were set primarily considering its role in bone health, but with the discovery of Vitamin D receptors throughout body tissues, new links with other health conditions are now studied, such as for diabetes and cardiovascul …
The dietary reference values for Vitamin D were set primarily considering its role in bone health, but with the discovery of Vitam …
Vitamin D and cardiovascular disease: systematic review and meta-analysis of prospective studies.
Grandi NC, Breitling LP, Brenner H. Grandi NC, et al. Prev Med. 2010 Sep-Oct;51(3-4):228-33. doi: 10.1016/j.ypmed.2010.06.013. Epub 2010 Jun 19. Prev Med. 2010. PMID: 20600257 Review.
BACKGROUND: Low serum 25-hydroxyvitamin D (25-OH-D) has recently been linked to cardiovascular diseases. This review summarizes evidence from prospective studies evaluating the prognostic value of 25-OH-D for cardiovascular disease incidence and mortality. ...Prospe …
BACKGROUND: Low serum 25-hydroxyvitamin D (25-OH-D) has recently been linked to cardiovascular diseases. This review summarizes evide …
Vitamin C revisited.
Oudemans-van Straaten HM, Spoelstra-de Man AM, de Waard MC. Oudemans-van Straaten HM, et al. Crit Care. 2014 Aug 6;18(4):460. doi: 10.1186/s13054-014-0460-x. Crit Care. 2014. PMID: 25185110 Free PMC article. Review.
High-dose vitamin C, however, provides a cheap, strong and multifaceted antioxidant, especially robust for resuscitation of the circulation. Vitamin C given as early as possible after the injurious event, or before if feasible, seems most effective. ...
High-dose vitamin C, however, provides a cheap, strong and multifaceted antioxidant, especially robust for resuscitation of the circu …
Niacin.
Kirkland JB, Meyer-Ficca ML. Kirkland JB, et al. Adv Food Nutr Res. 2018;83:83-149. doi: 10.1016/bs.afnr.2017.11.003. Epub 2018 Feb 1. Adv Food Nutr Res. 2018. PMID: 29477227
Insight into the role of niacin and various NAD-related diseases ranging from cancer, aging, and metabolic diseases to cardiovascular problems has shifted our view of niacin as a vitamin to current views that explore its potential as a therapeutic....
Insight into the role of niacin and various NAD-related diseases ranging from cancer, aging, and metabolic diseases to cardiovascular …
[What is a vitamin?].
Guilland JC. Guilland JC. Rev Prat. 2013 Oct;63(8):1060-9. Rev Prat. 2013. PMID: 24298822 Review. French.
In industrialized countries, the major vitamin deficiency syndromes have virtually disappeared. Today they are superseded by marginal deficits, characterized by insufficient vitamins reserves to maintain normal physiologic state. ...This assumption stems from the an …
In industrialized countries, the major vitamin deficiency syndromes have virtually disappeared. Today they are superseded by marginal …
The Vitamin D Assessment (ViDA) study - Design and main findings.
Scragg R. Scragg R. J Steroid Biochem Mol Biol. 2020 Apr;198:105562. doi: 10.1016/j.jsbmb.2019.105562. Epub 2019 Dec 3. J Steroid Biochem Mol Biol. 2020. PMID: 31809866 Clinical Trial.
This has initiated the conduct of several large clinical trials to determine if high dose vitamin D supplementation ( 2000 IU/day or monthly equivalent) prevents non-skeletal disease including cardiovascular disease, cancer and mortality. ...Information on study out …
This has initiated the conduct of several large clinical trials to determine if high dose vitamin D supplementation ( 2000 IU/day or …
Vitamin E supplementation in cardiovascular disease and cancer prevention: Part 1.
Pham DQ, Plakogiannis R. Pham DQ, et al. Ann Pharmacother. 2005 Nov;39(11):1870-8. doi: 10.1345/aph.1G211. Epub 2005 Sep 27. Ann Pharmacother. 2005. PMID: 16189282 Review.
OBJECTIVE: To review clinical trials evaluating the safety and efficacy of vitamin E supplementation in cardiovascular disease and cancer prevention. ...CONCLUSIONS: Available data do not support the supplementation of vitamin E in cardiovascular disea …
OBJECTIVE: To review clinical trials evaluating the safety and efficacy of vitamin E supplementation in cardiovascular disease …
A brief discussion of the benefit and mechanism of vitamin D supplementation on coronavirus disease 2019.
Cereda E, Bogliolo L, de Stefano L, Caccialanza R. Cereda E, et al. Curr Opin Clin Nutr Metab Care. 2021 Jan;24(1):102-107. doi: 10.1097/MCO.0000000000000701. Curr Opin Clin Nutr Metab Care. 2021. PMID: 33003119 Review.
PURPOSE OF REVIEW: Vitamin D exerts extraskeletal functions, including immunomodulatory activity, protection against respiratory tract infections and pleiotropic effects on the cardiovascular system. ...However, the pandemic progression and the increased know …
PURPOSE OF REVIEW: Vitamin D exerts extraskeletal functions, including immunomodulatory activity, protection against respiratory trac …
Putting cardiovascular disease and vitamin D insufficiency into perspective.
Zittermann A, Schleithoff SS, Koerfer R. Zittermann A, et al. Br J Nutr. 2005 Oct;94(4):483-92. doi: 10.1079/bjn20051544. Br J Nutr. 2005. PMID: 16197570 Free article. Review.
Interestingly, all these factors also have an influence on human UVB exposure and thus on vitamin D status. Several mechanisms might be responsible for a protective role of vitamin D in CVD. ...The first intervention trials indicate that vitamin D may suppres …
Interestingly, all these factors also have an influence on human UVB exposure and thus on vitamin D status. Several mechanisms might …
Vitamin D supplementation: what's known, what to do, and what's needed.
Haines ST, Park SK. Haines ST, et al. Pharmacotherapy. 2012 Apr;32(4):354-82. doi: 10.1002/phar.1037. Pharmacotherapy. 2012. PMID: 22461123 Review.
Epidemiologic evidence links vitamin D deficiency to autoimmune disease, cancer, cardiovascular disease, depression, dementia, infectious diseases, musculoskeletal decline, and more. ...For patients who are not at risk for developing vitamin D deficiency, sen …
Epidemiologic evidence links vitamin D deficiency to autoimmune disease, cancer, cardiovascular disease, depression, dementia, …
The vitamin D and calcium controversy: an update.
Lewis JR, Sim M, Daly RM. Lewis JR, et al. Curr Opin Rheumatol. 2019 Mar;31(2):91-97. doi: 10.1097/BOR.0000000000000584. Curr Opin Rheumatol. 2019. PMID: 30601231 Review.
There has also been high-quality evidence that vitamin D, daily or as a bolus, does not reduce the risk of cardiovascular events. ...Finally, there remain inconsistent findings for adverse cardiovascular effects of calcium supplements with or without vitam …
There has also been high-quality evidence that vitamin D, daily or as a bolus, does not reduce the risk of cardiovascular even …
Association between vitamin D and cardioprotection in adult patients.
Ferraz GC, Andrade RR, Reis FMP, Oliveira Neto OB, Omena CO, Jucá MJ, Sousa-Rodrigues CF, Barbosa FT. Ferraz GC, et al. Rev Assoc Med Bras (1992). 2020 Oct;66(10):1444-1448. doi: 10.1590/1806-9282.66.10.1444. Rev Assoc Med Bras (1992). 2020. PMID: 33174941 Free article. Review.
RESULTS: Twenty-three articles were identified from the electronic search that reported on physiological mechanisms relating the vitamin D axis and the cardiovascular system through receptors. Of the ten studies that evaluated the therapeutic effect of vit …
RESULTS: Twenty-three articles were identified from the electronic search that reported on physiological mechanisms relating the vitamin …
Vitamin D and Heart Failure.
Brinkley DM, Ali OM, Zalawadiya SK, Wang TJ. Brinkley DM, et al. Curr Heart Fail Rep. 2017 Oct;14(5):410-420. doi: 10.1007/s11897-017-0355-7. Curr Heart Fail Rep. 2017. PMID: 28808858 Review.
PURPOSE: Vitamin D is principally known for its role in calcium homeostasis, but preclinical studies implicate multiple pathways through which vitamin D may affect cardiovascular function and influence risk for heart failure. Many adults with cardiovascula …
PURPOSE: Vitamin D is principally known for its role in calcium homeostasis, but preclinical studies implicate multiple pathways thro …
Vitamin D and heart.
Camici M, Galetta F, Franzoni F, Carpi A, Zangeneh F. Camici M, et al. Intern Emerg Med. 2013 Apr;8 Suppl 1:S5-9. doi: 10.1007/s11739-013-0926-x. Intern Emerg Med. 2013. PMID: 23462894 Review.
The authors briefly review the biological effects of vitamin D on the heart and discuss the experimental and clinical studies related to the potential protective effect of vitamin D on the cardiovascular system. Experimental and observational studies i …
The authors briefly review the biological effects of vitamin D on the heart and discuss the experimental and clinical studies related …
Vitamin D status and risk of cardiovascular events: lessons learned via systematic review and meta-analysis.
Sokol SI, Tsang P, Aggarwal V, Melamed ML, Srinivas VS. Sokol SI, et al. Cardiol Rev. 2011 Jul-Aug;19(4):192-201. doi: 10.1097/CRD.0b013e31821da9a5. Cardiol Rev. 2011. PMID: 21646873 Review.
Accumulating data linking hypovitaminosis D to cardiovascular (CV) events has contributed to large increases in vitamin D testing and supplementation. ...Systematic review identified significant shortcomings in the literature, including variability in defining vi …
Accumulating data linking hypovitaminosis D to cardiovascular (CV) events has contributed to large increases in vitamin D test …
Vitamin D and atherosclerosis.
Menezes AR, Lamb MC, Lavie CJ, DiNicolantonio JJ. Menezes AR, et al. Curr Opin Cardiol. 2014 Nov;29(6):571-7. doi: 10.1097/HCO.0000000000000108. Curr Opin Cardiol. 2014. PMID: 25144342 Review.
PURPOSE OF REVIEW: To provide an overview of the association between vitamin D deficiency and atherosclerosis. RECENT FINDINGS: Vitamin D exerts protective effects on atherosclerosis through multiple mechanisms. ...Recently, there has been mounting evidence linking …
PURPOSE OF REVIEW: To provide an overview of the association between vitamin D deficiency and atherosclerosis. RECENT FINDINGS: Vi …
Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-a review of recent evidence.
Pludowski P, Holick MF, Pilz S, Wagner CL, Hollis BW, Grant WB, Shoenfeld Y, Lerchbaum E, Llewellyn DJ, Kienreich K, Soni M. Pludowski P, et al. Autoimmun Rev. 2013 Aug;12(10):976-89. doi: 10.1016/j.autrev.2013.02.004. Epub 2013 Mar 28. Autoimmun Rev. 2013. PMID: 23542507 Review.
Vitamin D deficiency/insufficiency is associated with all-cause mortality. CONCLUSIONS: Adequate vitamin D supplementation and sensible sunlight exposure to reach optimal vitamin D status are among the front line factors of prophylaxis for the spectrum of dis …
Vitamin D deficiency/insufficiency is associated with all-cause mortality. CONCLUSIONS: Adequate vitamin D supplementation and …
Vitamin D Effects on Bone Homeostasis and Cardiovascular System in Patients with Chronic Kidney Disease and Renal Transplant Recipients.
Cianciolo G, Cappuccilli M, Tondolo F, Gasperoni L, Zappulo F, Barbuto S, Iacovella F, Conte D, Capelli I, La Manna G. Cianciolo G, et al. Nutrients. 2021 Apr 25;13(5):1453. doi: 10.3390/nu13051453. Nutrients. 2021. PMID: 33922902 Free PMC article. Review.
This condition is further worsened by the compromised response of CKD patients to high-dose cholecalciferol supplementation due to the defective activation of renal hydroxylation of vitamin D. Currently, the literature lacks large and interventional studies on the so-calle …
This condition is further worsened by the compromised response of CKD patients to high-dose cholecalciferol supplementation due to the defec …
Vitamin neurotoxicity.
Snodgrass SR. Snodgrass SR. Mol Neurobiol. 1992 Spring;6(1):41-73. doi: 10.1007/BF02935566. Mol Neurobiol. 1992. PMID: 1463588 Review.
Because vitamin A and analogs enter the CNS better than most vitamins, and because retinoids have many effects on enzyme activity and gene expression, Vitamin A neurotoxicity is more likely than that of most, perhaps all other vitamins. ...High vita …
Because vitamin A and analogs enter the CNS better than most vitamins, and because retinoids have many effects on enzyme activ …
Protean manifestations of vitamin D deficiency, part 3: association with cardiovascular disease and disorders of the central and peripheral nervous systems.
Bell DS. Bell DS. South Med J. 2011 May;104(5):340-4. doi: 10.1097/01.SMJ.0000397894.02150.5f. South Med J. 2011. PMID: 21606713 Review.
As a result there is an increase in cardiovascular events (CVEs) associated with vitamin D deficiency. Vitamin D deficiency itself or secondary hyperparathyroidism or both may be responsible for the increase in CVEs. ...Vitamin D deficiency is early tr …
As a result there is an increase in cardiovascular events (CVEs) associated with vitamin D deficiency. Vitamin D defici …
Vitamins and cardiovascular disease.
Honarbakhsh S, Schachter M. Honarbakhsh S, et al. Br J Nutr. 2009 Apr;101(8):1113-31. doi: 10.1017/S000711450809123X. Epub 2008 Oct 1. Br J Nutr. 2009. PMID: 18826726 Review.
However, vitamin E and vitamin C have in combination shown long-term anti-atherogenic effects but their combined effect on clinical endpoints has been inconsistent. ...Through defining the right population group and the optimal vitamin combination we could po …
However, vitamin E and vitamin C have in combination shown long-term anti-atherogenic effects but their combined effect on cli …
Vitamin C Can Shorten the Length of Stay in the ICU: A Meta-Analysis.
Hemilä H, Chalker E. Hemilä H, et al. Nutrients. 2019 Mar 27;11(4):708. doi: 10.3390/nu11040708. Nutrients. 2019. PMID: 30934660 Free PMC article.
In six trials, orally administered vitamin C in doses of 1-3 g/day (weighted mean 2.0 g/day) reduced the length of ICU stay by 8.6% (p = 0.003). ...Given the insignificant cost of vitamin C, even an 8% reduction in ICU stay is worth exploring. The effects of vita …
In six trials, orally administered vitamin C in doses of 1-3 g/day (weighted mean 2.0 g/day) reduced the length of ICU stay by 8.6% ( …
Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis.
Hill A, Clasen KC, Wendt S, Majoros ÁG, Stoppe C, Adhikari NKJ, Heyland DK, Benstoem C. Hill A, et al. Nutrients. 2019 Sep 4;11(9):2103. doi: 10.3390/nu11092103. Nutrients. 2019. PMID: 31487905 Free PMC article.
Past clinical trials and meta-analyses have focused predominantly on occurrence of postoperative atrial fibrillation. Therefore, we investigated the influence of perioperative vitamin C administration on clinically relevant parameters closer related to the patient's …
Past clinical trials and meta-analyses have focused predominantly on occurrence of postoperative atrial fibrillation. Therefore, we investig …
[Vitamin D and cognition in the elderly].
Constans T, Mondon K, Annweiler C, Hommet C. Constans T, et al. Psychol Neuropsychiatr Vieil. 2010 Dec;8(4):255-62. doi: 10.1684/pnv.2010.0233. Psychol Neuropsychiatr Vieil. 2010. PMID: 21147664 Free article. Review. French.
The understanding of the role of vitamin D in maintaining good health has considerably increased in the recent years. There is a growing evidence that vitamin D has not only a beneficial effect to prevent osteoporosis and the risk of falls in the elderly, but also m …
The understanding of the role of vitamin D in maintaining good health has considerably increased in the recent years. There is a grow …
Cost-Effectiveness and Estimated Health Benefits of Treating Patients with Vitamin D in Pre-Dialysis.
Snyder S, Hollenbeak CS, Kalantar-Zadeh K, Gitlin M, Ashfaq A. Snyder S, et al. Forum Health Econ Policy. 2020 Mar 5;23(1):/j/fhep.2020.23.issue-1/fhep-2019-0020/fhep-2019-0020.xml. doi: 10.1515/fhep-2019-0020. Forum Health Econ Policy. 2020. PMID: 32134730
Objective The objective of this study was to estimate the cost-effectiveness of earlier vitamin D treatment in CKD patients not on dialysis with vitamin D insufficiency and SHPT. ...Further research demonstrating causal relationships between vitamin D therapy …
Objective The objective of this study was to estimate the cost-effectiveness of earlier vitamin D treatment in CKD patients not on di …
A review of vitamin D status and CVD.
Cashman KD. Cashman KD. Proc Nutr Soc. 2014 Feb;73(1):65-72. doi: 10.1017/S0029665113003595. Epub 2013 Oct 9. Proc Nutr Soc. 2014. PMID: 24103845 Review.
Beyond the well-accepted effects on the skeleton, low vitamin D status has been linked to increased risk of several non-skeletal disease, including CVD. ...Finally, the review summarises current serum 25(OH)D concentrations within a select number of adult populations in th …
Beyond the well-accepted effects on the skeleton, low vitamin D status has been linked to increased risk of several non-skeletal dise …
Optimal Vitamin D Supplementation Levels for Cardiovascular Disease Protection.
Lugg ST, Howells PA, Thickett DR. Lugg ST, et al. Dis Markers. 2015;2015:864370. doi: 10.1155/2015/864370. Epub 2015 Sep 8. Dis Markers. 2015. PMID: 26435569 Free PMC article. Review.
First described in relation to musculoskeletal disease, there is accumulating data to suggest that vitamin D may play an important role in cardiovascular disease (CVD). ...The role of vitamin D levels as a disease marker for all-cause mortality is also discus …
First described in relation to musculoskeletal disease, there is accumulating data to suggest that vitamin D may play an important ro …
A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
Kumar V, Yadav AK, Lal A, Kumar V, Singhal M, Billot L, Gupta KL, Banerjee D, Jha V. Kumar V, et al. J Am Soc Nephrol. 2017 Oct;28(10):3100-3108. doi: 10.1681/ASN.2017010003. Epub 2017 Jun 30. J Am Soc Nephrol. 2017. PMID: 28667080 Free PMC article. Clinical Trial.
Vitamin D deficiency associates with mortality in patients with CKD, and vitamin D supplementation might mitigate cardiovascular disease risk in CKD. ...Intervention also led to significant favorable changes in pulse wave velocity and circulating IL-6 levels. …
Vitamin D deficiency associates with mortality in patients with CKD, and vitamin D supplementation might mitigate cardiovas …
Modulatory effects of melatonin and vitamin C on oxidative stress-mediated haemolytic anaemia and associated cardiovascular dysfunctions in rats.
Ajibade TO, Oyagbemi AA, Durotoye LA, Omóbòwálé TO, Asenuga ER, Olayemi FO. Ajibade TO, et al. J Complement Integr Med. 2017 Mar 1;14(1):/j/jcim.2017.14.issue-1/jcim-2015-0082/jcim-2015-0082.xml. doi: 10.1515/jcim-2015-0082. J Complement Integr Med. 2017. PMID: 28237973
Pathology of the heart and kidney was also observed in PHE treated group. However, treatment with MLT and vitamin C improved enzymic and non-enzymic antioxidant system together with the restoration of SBP, DBP and MABP to near normal. The architectural anarchy obser …
Pathology of the heart and kidney was also observed in PHE treated group. However, treatment with MLT and vitamin C improved enzymic …
Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium.
Gibson CC, Davis CT, Zhu W, Bowman-Kirigin JA, Walker AE, Tai Z, Thomas KR, Donato AJ, Lesniewski LA, Li DY. Gibson CC, et al. PLoS One. 2015 Oct 15;10(10):e0140370. doi: 10.1371/journal.pone.0140370. eCollection 2015. PLoS One. 2015. PMID: 26469335 Free PMC article.
Vitamin D is a known modulator of inflammation. Native dietary vitamin D3 is thought to be bio-inactive, and beneficial vitamin D3 effects are thought to be largely mediated by the metabolite 1,25(OH)2D3. ...In this manuscript we show that the presumed inacti …
Vitamin D is a known modulator of inflammation. Native dietary vitamin D3 is thought to be bio-inactive, and beneficial vit …
Vitamin E in oxidant stress-related cardiovascular pathologies: focus on experimental studies.
Turan B, Vassort G. Turan B, et al. Curr Pharm Des. 2011;17(21):2155-69. doi: 10.2174/138161211796957454. Curr Pharm Des. 2011. PMID: 21774778 Review.
Cardiovascular disease is the world's largest killer, claiming 17.1 million lives a year. ...Several recent studies, besides earlier ones, have reported beneficial effects of therapy with antioxidant agents, including trace elements, vitamins (E and/or C), ot …
Cardiovascular disease is the world's largest killer, claiming 17.1 million lives a year. ...Several recent studies, besides e …
The current role and therapeutic targets of vitamin D in gastrointestinal inflammation and cancer.
Cai GH, Li MX, Lu L, Yi Chan RL, Wang JH, Cho CH. Cai GH, et al. Curr Pharm Des. 2015;21(21):2917-23. doi: 10.2174/1381612821666150514103105. Curr Pharm Des. 2015. PMID: 26004419 Review.
Vitamin D, beyond its classical roles in the regulation of calcium and phosphorus homeostasis and bone metabolism, has been implicated in multiple pathological processes, including progression from inflammation to cancer development and also involvement in autoimmune disea …
Vitamin D, beyond its classical roles in the regulation of calcium and phosphorus homeostasis and bone metabolism, has been implicate …
Vitamin C to Improve Organ Dysfunction in Cardiac Surgery Patients-Review and Pragmatic Approach.
Hill A, Wendt S, Benstoem C, Neubauer C, Meybohm P, Langlois P, Adhikari NK, Heyland DK, Stoppe C. Hill A, et al. Nutrients. 2018 Jul 27;10(8):974. doi: 10.3390/nu10080974. Nutrients. 2018. PMID: 30060468 Free PMC article. Review.
Vitamin C protects important organ systems (cardiovascular, neurologic and renal systems) during inflammation and oxidative stress. It also influences coagulation and inflammation; its application might prevent organ damage. The current evidence of vitamin C' …
Vitamin C protects important organ systems (cardiovascular, neurologic and renal systems) during inflammation and oxidative st …
Vitamin D screening.
Minisola S, Colangelo L, Pepe J, Occhiuto M, Piazzolla V, Renella M, Biamonte F, Sonato C, Cilli M, Cipriani C. Minisola S, et al. J Endocrinol Invest. 2020 Aug;43(8):1047-1051. doi: 10.1007/s40618-020-01220-w. Epub 2020 Mar 18. J Endocrinol Invest. 2020. PMID: 32189163 Review.
At present, there is no need and no sufficient evidence to support universal screening for vitamin D status. There are four categories of subjects in whom there is no requirement for screening, since a number of studies indicate beneficial effects of vitamin D suppl …
At present, there is no need and no sufficient evidence to support universal screening for vitamin D status. There are four categorie …
Vitamin, mineral, and multivitamin supplements for the primary prevention of cardiovascular disease and cancer: U.S. Preventive services Task Force recommendation statement.
Moyer VA; U.S. Preventive Services Task Force. Moyer VA, et al. Ann Intern Med. 2014 Apr 15;160(8):558-64. doi: 10.7326/M14-0198. Ann Intern Med. 2014. PMID: 24566474 Free article.
DESCRIPTION: Update of the 2003 U.S. Preventive Services Task Force (USPSTF) recommendation on vitamin supplementation to prevent cardiovascular disease and cancer. ...(I statement). The USPSTF recommends against beta-carotene or vitamin E supplements …
DESCRIPTION: Update of the 2003 U.S. Preventive Services Task Force (USPSTF) recommendation on vitamin supplementation to prev …
Vitamin and mineral supplements.
Hamrick I, Counts SH. Hamrick I, et al. Prim Care. 2008 Dec;35(4):729-47. doi: 10.1016/j.pop.2008.07.012. Prim Care. 2008. PMID: 18928827
Some vitamin and mineral supplements have proved to be clinically useful in preventing various diseases and health problems. ...Primary care physicians should be familiar with the latest research so they can be proactive in advising patients about proper use of vitamins …
Some vitamin and mineral supplements have proved to be clinically useful in preventing various diseases and health problems. ...Prima …
An update on vitamin E, tocopherol and tocotrienol-perspectives.
Colombo ML. Colombo ML. Molecules. 2010 Mar 24;15(4):2103-13. doi: 10.3390/molecules15042103. Molecules. 2010. PMID: 20428030 Free PMC article. Review.
Vitamin E, like tocotrienols and tocopherols, is constituted of compounds essential for animal cells. ...From a health point of view, at the moment there is a great interest in the natural forms of tocochromanols, because they are considered promising compounds able to mai …
Vitamin E, like tocotrienols and tocopherols, is constituted of compounds essential for animal cells. ...From a health point of view, …
Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies.
Chowdhury R, Kunutsor S, Vitezova A, Oliver-Williams C, Chowdhury S, Kiefte-de-Jong JC, Khan H, Baena CP, Prabhakaran D, Hoshen MB, Feldman BS, Pan A, Johnson L, Crowe F, Hu FB, Franco OH. Chowdhury R, et al. BMJ. 2014 Apr 1;348:g1903. doi: 10.1136/bmj.g1903. BMJ. 2014. PMID: 24690623 Free PMC article. Review.
OBJECTIVE: To evaluate the extent to which circulating biomarker and supplements of vitamin D are associated with mortality from cardiovascular, cancer, or other conditions, under various circumstances. ...Subgroup analyses in the observational studies indicated tha …
OBJECTIVE: To evaluate the extent to which circulating biomarker and supplements of vitamin D are associated with mortality from c …
Effects of moderate exercise and a multiple vitamin and mineral complex on the arterial wall.
Potoră CS, Tache S, Albu A, Nagy AL. Potoră CS, et al. Rom J Morphol Embryol. 2018;59(1):249-256. Rom J Morphol Embryol. 2018. PMID: 29940635 Free article.
Its beneficial role may be due to a decrease in oxidative stress. The association of vitamin and mineral supplements to exercise determined contradictory effects on arterial wall and oxidative stress parameters. The aim of this experimental study was to evaluate the effect …
Its beneficial role may be due to a decrease in oxidative stress. The association of vitamin and mineral supplements to exercise dete …
Calciotrophic hormones and hyperglycemia modulate vitamin D receptor and 25 hydroxyy vitamin D 1-alpha hydroxylase mRNA expression in human vascular smooth muscle cells.
Somjen D, Knoll E, Sharon O, Many A, Stern N. Somjen D, et al. J Steroid Biochem Mol Biol. 2015 Apr;148:210-3. doi: 10.1016/j.jsbmb.2014.11.007. Epub 2014 Nov 13. J Steroid Biochem Mol Biol. 2015. PMID: 25448744 Review.
Estrogen receptors (ERalpha and ERbeta), the vitamin D receptor (VDR) and 25 hydroxyy vitamin D 1-alpha hydroxylase (1OHase) mRNA are expressed in vascular smooth muscle cells (VSMC). ...In conclusion, calcitrophic hormones modify VSMC growth and concomitantly affec …
Estrogen receptors (ERalpha and ERbeta), the vitamin D receptor (VDR) and 25 hydroxyy vitamin D 1-alpha hydroxylase (1OHase) m …
Prevalence of vitamin D insufficiency and evidence for disease prevention in the older population.
Kühn J, Trotz P, Stangl GI. Kühn J, et al. Z Gerontol Geriatr. 2018 Jul;51(5):567-572. doi: 10.1007/s00391-018-1390-z. Epub 2018 Apr 17. Z Gerontol Geriatr. 2018. PMID: 29666919 Review. English.
The role of vitamin D in the prevention of falls and frailty remains unclear. ...To conclude, vitamin D, particularly combined with calcium, has moderately beneficial effects on the skeletal system and is useful for the prevention of respiratory tract infecti …
The role of vitamin D in the prevention of falls and frailty remains unclear. ...To conclude, vitamin D, particularly combined …
Vitamin D and chronic disease prevention.
Welsh P, Sattar N. Welsh P, et al. BMJ. 2014 Apr 1;348:g2280. doi: 10.1136/bmj.g2280. BMJ. 2014. PMID: 24690627 Free article. No abstract available.
Routine vitamin supplementation to prevent cancer and cardiovascular disease.
U. S. Preventive Services Task Force. U. S. Preventive Services Task Force. Nutr Clin Care. 2003 Oct-Dec;6(3):102-7. Nutr Clin Care. 2003. PMID: 14979452 Review.
This article summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on routine vitamin supplementation to prevent cancer and cardiovascular disease and the supporting scientific evidence. The USPSTF concludes that the evidence is insuffic …
This article summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on routine vitamin supplementation to …
Increasing vitamin C content in plant foods to improve their nutritional value-successes and challenges.
Gallie DR. Gallie DR. Nutrients. 2013 Aug 30;5(9):3424-46. doi: 10.3390/nu5093424. Nutrients. 2013. PMID: 23999762 Free PMC article. Review.
Vitamin C serves as a cofactor in the synthesis of collagen needed to support cardiovascular function, maintenance of cartilage, bones, and teeth, as well as being required in wound healing. ...Only low levels of the vitamin are required to prevent scurvy but …
Vitamin C serves as a cofactor in the synthesis of collagen needed to support cardiovascular function, maintenance of cartilag …
[Vitamin D hormone system and diabetes mellitus: lessons from selective activators of vitamin D receptor and diabetes mellitus].
Jódar-Gimeno E, Muñoz-Torres M. Jódar-Gimeno E, et al. Endocrinol Nutr. 2013 Feb;60(2):87-95. doi: 10.1016/j.endonu.2012.04.005. Epub 2012 Jul 2. Endocrinol Nutr. 2013. PMID: 22763025 Review. Spanish.
The vitamin D hormone system has significant skeletal and extra-skeletal effects. ...Specifically, influence of vitamin D on the renin-angiotensin-aldosterone system, inflammatory response, and urinary albumin excretion could explain the relevant impac …
The vitamin D hormone system has significant skeletal and extra-skeletal effects. ...Specifically, influence of vitamin …
[Influence of vitamin D on cardiovascular risk].
Cormier C, Courbebaisse M. Cormier C, et al. Presse Med. 2013 Oct;42(10):1364-70. doi: 10.1016/j.lpm.2013.09.002. Epub 2013 Oct 3. Presse Med. 2013. PMID: 24090586 Review. French.
Few interventional studies have reported a positive effect of native vitamin D supplementation on intermediary parameters of insulin resistance, of cardiovascular risk and on major cardiovascular events and mortality....
Few interventional studies have reported a positive effect of native vitamin D supplementation on intermediary parameters of insulin …
Menaquinone-7 Supplementation to Reduce Vascular Calcification in Patients with Coronary Artery Disease: Rationale and Study Protocol (VitaK-CAC Trial).
Vossen LM, Schurgers LJ, van Varik BJ, Kietselaer BL, Vermeer C, Meeder JG, Rahel BM, van Cauteren YJ, Hoffland GA, Rennenberg RJ, Reesink KD, de Leeuw PW, Kroon AA. Vossen LM, et al. Nutrients. 2015 Oct 28;7(11):8905-15. doi: 10.3390/nu7115443. Nutrients. 2015. PMID: 26516910 Free PMC article. Clinical Trial.
An important inhibitor of calcification is vitamin K-dependent matrix Gla protein (MGP). Both preclinical and clinical studies have shown that inhibition of the vitamin K-cycle by vitamin K antagonists (VKA) results in elevated uncarboxylated MGP (ucMGP) and …
An important inhibitor of calcification is vitamin K-dependent matrix Gla protein (MGP). Both preclinical and clinical studies have s …
[Vitamin D: skeletal and extra skeletal effects; recommendations for good practice].
Briot K, Audran M, Cortet B, Fardellone P, Marcelli C, Orcel P, Vellas B, Thomas T, Roux C. Briot K, et al. Presse Med. 2009 Jan;38(1):43-54. doi: 10.1016/j.lpm.2008.08.008. Epub 2008 Nov 11. Presse Med. 2009. PMID: 19004609 Review. French.
During the past decade, major advances have reported the importance of the vitamin D on the bone metabolism, and recent studies have suggested the potential non skeletal effects of the vitamin D. ...A possible role of vitamin D has been implicated in the redu …
During the past decade, major advances have reported the importance of the vitamin D on the bone metabolism, and recent studies have …
Routine vitamin supplementation to prevent cardiovascular disease: a summary of the evidence for the U.S. Preventive Services Task Force.
Morris CD, Carson S. Morris CD, et al. Ann Intern Med. 2003 Jul 1;139(1):56-70. doi: 10.7326/0003-4819-139-1-200307010-00014. Ann Intern Med. 2003. PMID: 12834320 Free article. Review.
PURPOSE: To assess the evidence of the effectiveness of vitamin supplementation, specifically vitamins A, C, and E; beta-carotene; folic acid; antioxidant combinations; and multivitamin supplements, in preventing cardiovascular disease. ...CONCLUSIONS: Some g …
PURPOSE: To assess the evidence of the effectiveness of vitamin supplementation, specifically vitamins A, C, and E; beta-carot …
Place of vitamin D in the prevention of premature aging and the development of age-associated diseases.
Drapkina OM, Shepel RN, Fomin VV, Svistunov АА. Drapkina OM, et al. Ter Arkh. 2018 Feb 14;90(1):69-75. doi: 10.26442/terarkh201890169-75. Ter Arkh. 2018. PMID: 30701762 Review.
At the same time there is growing evidence geroprotective properties of vitamin D. In this review, described in detail the possible mechanisms by which vitamin D affects differentiation, cell proliferation and apoptosis, and describes the potential benefits of this …
At the same time there is growing evidence geroprotective properties of vitamin D. In this review, described in detail the possible m …
Vitamin D in kidney transplant recipients.
Battaglia Y, Cojocaru E, Fiorini F, Granata A, Esposito P, Russo L, Bortoluzzi A, Storari A, Russo D. Battaglia Y, et al. Clin Nephrol. 2020 Feb;93(2):57-64. doi: 10.5414/CN109735. Clin Nephrol. 2020. PMID: 31319906 Review.
Kidney transplant recipients (KTRs) are susceptible to low levels of vitamin D, which may be responsible for mineral and bone metabolism disorders and play some role in the occurrence of cardiovascular, metabolic, immunologic, neoplastic, and infectious complication …
Kidney transplant recipients (KTRs) are susceptible to low levels of vitamin D, which may be responsible for mineral and bone metabol …
Routine vitamin supplementation to prevent cancer and cardiovascular disease: recommendations and rationale.
U.S. Preventive Services Task Force. U.S. Preventive Services Task Force. Ann Intern Med. 2003 Jul 1;139(1):51-5. doi: 10.7326/0003-4819-139-1-200307010-00013. Ann Intern Med. 2003. PMID: 12834319 Free article.
This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on routine vitamin supplementation to prevent cancer and cardiovascular disease and the supporting scientific evidence. Part of the information on which this statement …
This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on routine vitamin supplementation …
Antioxidant vitamins and their use in preventing cardiovascular disease.
Farbstein D, Kozak-Blickstein A, Levy AP. Farbstein D, et al. Molecules. 2010 Nov 9;15(11):8098-110. doi: 10.3390/molecules15118098. Molecules. 2010. PMID: 21063272 Free PMC article. Review.
However, while in vitro and in vivo studies showed promising antiatherogenic effects for vitamins C and E, clinical trials in which patients were given high doses of vitamin E or C showed no benefit and even possible harm. This review will attempt to summarize the k …
However, while in vitro and in vivo studies showed promising antiatherogenic effects for vitamins C and E, clinical trials in which p …
New cardiovascular risk factors: homocysteine and vitamins involved in homocysteine metabolism.
De Caterina R, Zampolli A, Madonna R, Fioretti P, Vanuzzo D. De Caterina R, et al. Ital Heart J. 2004 Jun;5 Suppl 6:19S-24S. Ital Heart J. 2004. PMID: 15185912 Review.
There are also, however, suggestions from the literature that group B vitamins, and in particular vitamin B6 (pyridoxine/pyridoxal-phosphate), are modulators of cardiovascular risk independent of homocysteine. The results of a recent study of ours, with a lon …
There are also, however, suggestions from the literature that group B vitamins, and in particular vitamin B6 (pyridoxine/pyrid …
Vitamin CNa enhances the antioxidant ability of chicken myocardium cells and induces heat shock proteins to relieve heat stress injury.
Yin B, Di L, Tang S, Bao E. Yin B, et al. Res Vet Sci. 2020 Dec;133:124-130. doi: 10.1016/j.rvsc.2020.09.008. Epub 2020 Sep 11. Res Vet Sci. 2020. PMID: 32977120
In order to explore the function of vitamin C (VC) and VC-Na in the relief of heat stress injury in chicken cardiomyocytes, 150 30-day-old specific-pathogen-free chickens were randomly divided into a control group (fed normal drinking water), a VC group (50 mug/mL VC in dr …
In order to explore the function of vitamin C (VC) and VC-Na in the relief of heat stress injury in chicken cardiomyocytes, 150 30-da …
Vitamin E and heart disease: basic science to clinical intervention trials.
Pryor WA. Pryor WA. Free Radic Biol Med. 2000 Jan 1;28(1):141-64. doi: 10.1016/s0891-5849(99)00224-5. Free Radic Biol Med. 2000. PMID: 10656300 Review.
There is some evidence that the ex vivo oxidizability of a subject's LDL is predictive of future heart events. This background in basic science and observational studies, coupled with the safety of vitamin E, led to the initiation of clinical intervention trials. .. …
There is some evidence that the ex vivo oxidizability of a subject's LDL is predictive of future heart events. This background in bas …
Impact of vitamin D3 on cardiovascular responses to glucocorticoid excess.
Ahmed MA. Ahmed MA. J Physiol Biochem. 2013 Jun;69(2):267-76. doi: 10.1007/s13105-012-0209-4. Epub 2012 Sep 19. J Physiol Biochem. 2013. PMID: 22991185
Although the cardiovascular system is not a classical target for 1,25-dihydroxyvitamin D3, both cardiac myocytes and vascular smooth muscle cells respond to this hormone. The present study aimed to elucidate the effect of active vitamin D3 on cardiovascula …
Although the cardiovascular system is not a classical target for 1,25-dihydroxyvitamin D3, both cardiac myocytes and vascular …
Vitamins for Cardiovascular Diseases: Is the Expense Justified?
Sultan S, Murarka S, Jahangir A, Mookadam F, Tajik AJ, Jahangir A. Sultan S, et al. Cardiol Rev. 2017 Nov/Dec;25(6):298-308. doi: 10.1097/CRD.0000000000000150. Cardiol Rev. 2017. PMID: 28984669 Review.
Despite the knowledge that a well-balanced diet provides most of the nutritional requirements, the use of supplemental vitamins is widespread among adults in the United States. Evidence from large randomized controlled trials over the last 2 decades does not support vit …
Despite the knowledge that a well-balanced diet provides most of the nutritional requirements, the use of supplemental vitamins is wi …
Effect of Combined Treatment With Folic Acid, Vitamin B(6), and Vitamin B(12) on Plasma Biomarkers of Inflammation and Endothelial Dysfunction in Women.
Christen WG, Cook NR, Van Denburgh M, Zaharris E, Albert CM, Manson JE. Christen WG, et al. J Am Heart Assoc. 2018 May 18;7(11):e008517. doi: 10.1161/JAHA.117.008517. J Am Heart Assoc. 2018. PMID: 29776960 Free PMC article. Clinical Trial.
BACKGROUND: The aim of this study was to determine whether reducing plasma homocysteine concentrations with long-term, combined treatment with folic acid, vitamin B(6), and vitamin B(12) alters plasma biomarkers of inflammation and endothelial dysfunction in women a …
BACKGROUND: The aim of this study was to determine whether reducing plasma homocysteine concentrations with long-term, combined treatment wi …
Effect of vitamin D supplementation on measures of arterial stiffness: a systematic review and meta-analysis of randomized controlled trials.
Rodríguez AJ, Scott D, Srikanth V, Ebeling P. Rodríguez AJ, et al. Clin Endocrinol (Oxf). 2016 May;84(5):645-57. doi: 10.1111/cen.13031. Epub 2016 Feb 26. Clin Endocrinol (Oxf). 2016. PMID: 26824510 Review.
Arterial stiffness has prognostic value for cardiovascular disease risk. The aim of this systematic review was to clarify the literature surrounding the use of vitamin D to ameliorate arterial stiffness. ...Therefore, large and well-designed randomized studies are r …
Arterial stiffness has prognostic value for cardiovascular disease risk. The aim of this systematic review was to clarify the literat …
Clinical Significance of Analysis of Vitamin D Status in Various Diseases.
Kowalówka M, Główka AK, Karaźniewicz-Łada M, Kosewski G. Kowalówka M, et al. Nutrients. 2020 Sep 11;12(9):2788. doi: 10.3390/nu12092788. Nutrients. 2020. PMID: 32933052 Free PMC article. Review.
Vitamin D plays a role not only in the proper functioning of the skeletal system and the calcium-phosphate equilibrium, but also in the immune system, the cardiovascular system and the growth and division of cells. ...This article reviews the re …
Vitamin D plays a role not only in the proper functioning of the skeletal system and the calcium-phosphate equilibrium, but al …
Vitamin D and the heart: why we need large-scale clinical trials.
Manson JE. Manson JE. Cleve Clin J Med. 2010 Dec;77(12):903-10. doi: 10.3949/ccjm.77gr.10004. Cleve Clin J Med. 2010. PMID: 21147944 Free article.
Although vitamin D supplementation appears to be a promising intervention for reducing risks of cancer, cardiovascular disease, and other chronic diseases, existing evidence on its benefits and risks is limited and inconclusive. Recruitment is now under way for the …
Although vitamin D supplementation appears to be a promising intervention for reducing risks of cancer, cardiovascular disease …
Effects of vitamin D supplementation on cardiometabolic outcomes in children and adolescents: a systematic review and meta-analysis of randomized controlled trials.
Hauger H, Laursen RP, Ritz C, Mølgaard C, Lind MV, Damsgaard CT. Hauger H, et al. Eur J Nutr. 2020 Apr;59(3):873-884. doi: 10.1007/s00394-019-02150-x. Epub 2020 Feb 14. Eur J Nutr. 2020. PMID: 32060613
PURPOSE: In observational studies, higher S-25-hydroxyvitamin D [S-25(OH)D] has been associated with a more favorable cardiometabolic profile in childhood, but results may be confounded. ...Vitamin D supplementation had no other effects. However, in the meta- …
PURPOSE: In observational studies, higher S-25-hydroxyvitamin D [S-25(OH)D] has been associated with a more favorable cardiome …
[Update on vitamin D and evaluation of vitamin D status].
Souberbielle JC, Prié D, Courbebaisse M, Friedlander G, Houillier P, Maruani G, Cavalier E, Cormier C. Souberbielle JC, et al. Ann Endocrinol (Paris). 2008 Dec;69(6):501-10. doi: 10.1016/j.ando.2008.07.010. Epub 2008 Sep 18. Ann Endocrinol (Paris). 2008. PMID: 18804195 Free article. Review. French.
Knowledge about vitamin D has greatly improved during the last few years. Vitamin D cannot any more be considered as exclusively necessary to prevent ricket/osteomalacia. ...Vitamin D status can easily be assessed by measuring serum 25 hydroxy vitamin …
Knowledge about vitamin D has greatly improved during the last few years. Vitamin D cannot any more be considered as exclusive …
High-Dose versus Low-Dose Vitamin D Supplementation and Arterial Stiffness among Individuals with Prehypertension and Vitamin D Deficiency.
Zaleski A, Panza G, Swales H, Arora P, Newton-Cheh C, Wang T, Thompson PD, Taylor B. Zaleski A, et al. Dis Markers. 2015;2015:918968. doi: 10.1155/2015/918968. Epub 2015 Sep 16. Dis Markers. 2015. PMID: 26451070 Free PMC article. Clinical Trial.
INTRODUCTION: Vitamin D deficiency is associated with the onset and progression of hypertension and cardiovascular disease (CVD). ...We sought to examine the differential effect of high-dose versus low-dose vitamin D supplementation on markers of arterial sti …
INTRODUCTION: Vitamin D deficiency is associated with the onset and progression of hypertension and cardiovascular disease (CV …
Effect of vitamin E and C supplements on antioxidant defense system in cardiovascular disease patients in Zahedan, southeast Iran.
Karajibani M, Hashemi M, Montazerifar F, Dikshit M. Karajibani M, et al. J Nutr Sci Vitaminol (Tokyo). 2010;56(6):436-40. doi: 10.3177/jnsv.56.436. J Nutr Sci Vitaminol (Tokyo). 2010. PMID: 21422713 Free article. Clinical Trial.
Oxidative stress plays an important role in the pathogenesis of cardiovascular disease (CVD). Growing evidence suggest that antioxidant vitamins might reduce the risk of disease outcomes by their ability to scavenge free radicals. ...The results suggest that supplem …
Oxidative stress plays an important role in the pathogenesis of cardiovascular disease (CVD). Growing evidence suggest that antioxida …
The virtues of vitamin D--but how much is too much?
Shroff R, Knott C, Rees L. Shroff R, et al. Pediatr Nephrol. 2010 Sep;25(9):1607-20. doi: 10.1007/s00467-010-1499-9. Pediatr Nephrol. 2010. PMID: 20393752 Review.
Most tissues in the body have a vitamin D receptor and the enzymatic machinery to convert 'nutritional' 25-hydroxyvitamin D to the active form 1,25-dihydroxyvitamin D; it is estimated that 3% of the human genome is regulated by the vitamin D endocrine system. …
Most tissues in the body have a vitamin D receptor and the enzymatic machinery to convert 'nutritional' 25-hydroxyvitamin D to the ac …
Effect of Vitamin K Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis.
Verma H, Garg R. Verma H, et al. Endocr Metab Immune Disord Drug Targets. 2019;19(1):13-25. doi: 10.2174/1871530318666180703125007. Endocr Metab Immune Disord Drug Targets. 2019. PMID: 29968548
BACKGROUND: Multiple cross sectional and longitudinal studies reported the benefits of vitamin K intake for management of cardiometabolic risk factors so as to minimize the risk of cardiovascular diseases. ...A total of 13 trials were selected for inclusion into the …
BACKGROUND: Multiple cross sectional and longitudinal studies reported the benefits of vitamin K intake for management of cardiometab …
Potential of vitamin D in treating diabetic cardiomyopathy.
Lee TW, Lee TI, Chang CJ, Lien GS, Kao YH, Chao TF, Chen YJ. Lee TW, et al. Nutr Res. 2015 Apr;35(4):269-79. doi: 10.1016/j.nutres.2015.02.005. Epub 2015 Feb 24. Nutr Res. 2015. PMID: 25770692 Review.
Currently, effective treatments for diabetic cardiomyopathy are limited. Vitamin D exerts pleiotropic effects on the cardiovascular system and is associated with DM. ...Herein, we reviewed vitamin D metabolism; evaluated the molecular, cellular, and ne …
Currently, effective treatments for diabetic cardiomyopathy are limited. Vitamin D exerts pleiotropic effects on the cardiovascula …
Vitamin D and osteogenic differentiation in the artery wall.
Hsu JJ, Tintut Y, Demer LL. Hsu JJ, et al. Clin J Am Soc Nephrol. 2008 Sep;3(5):1542-7. doi: 10.2215/CJN.01220308. Epub 2008 Jun 18. Clin J Am Soc Nephrol. 2008. PMID: 18562594 Free PMC article.
Recent epidemiologic evidence suggests that there is a narrow range of vitamin D levels in which vascular function is optimized. Levels above or below this range seem to confer a significant increase in risk for cardiovascular disease. ...These findings raise intere …
Recent epidemiologic evidence suggests that there is a narrow range of vitamin D levels in which vascular function is optimized. Leve …
Atherosclerosis and oxidant stress: the end of the road for antioxidant vitamin treatment?
Thomson MJ, Puntmann V, Kaski JC. Thomson MJ, et al. Cardiovasc Drugs Ther. 2007 Jun;21(3):195-210. doi: 10.1007/s10557-007-6027-1. Cardiovasc Drugs Ther. 2007. PMID: 17484034 Review.
Extensive experimental data have revealed a central role for oxidative stress in atherogenesis and suggested a potential role for 'antioxidant' treatment in cardiovascular disease (CVD) [1-11]. Experimental data, however, have not translated into clinical benefit: most ant …
Extensive experimental data have revealed a central role for oxidative stress in atherogenesis and suggested a potential role for 'antioxida …
Different vitamin D receptor agonists exhibit differential effects on endothelial function and aortic gene expression in 5/6 nephrectomized rats.
Wu-Wong JR, Li X, Chen YW. Wu-Wong JR, et al. J Steroid Biochem Mol Biol. 2015 Apr;148:202-9. doi: 10.1016/j.jsbmb.2014.12.002. Epub 2014 Dec 10. J Steroid Biochem Mol Biol. 2015. PMID: 25500070 Review.
Endothelial dysfunction, common in chronic kidney disease (CKD), significantly increases cardiovascular disease risk in CKD patients. This study investigates whether different vitamin D receptor agonists exhibit different effects on endothelial function and on aorti …
Endothelial dysfunction, common in chronic kidney disease (CKD), significantly increases cardiovascular disease risk in CKD patients. …
The role of the antioxidant vitamin supplementation in the prevention of cardiovascular diseases.
Riccioni G, Bucciarelli T, Mancini B, Di Ilio C, Capra V, D'Orazio N. Riccioni G, et al. Expert Opin Investig Drugs. 2007 Jan;16(1):25-32. doi: 10.1517/13543784.16.1.25. Expert Opin Investig Drugs. 2007. PMID: 17155851 Review.
Industrial and technological revolutions have resulted in dramatic shifts in the diseases that are responsible for illness and death. In particular, cardiovascular disease (CVD) has emerged as the dominant chronic disease in many parts of the world. ...A large number of de …
Industrial and technological revolutions have resulted in dramatic shifts in the diseases that are responsible for illness and death. In par …
The potential role of antioxidant vitamins in preventing cardiovascular diseases and cancers.
Hercberg S, Galan P, Preziosi P, Alfarez MJ, Vazquez C. Hercberg S, et al. Nutrition. 1998 Jun;14(6):513-20. doi: 10.1016/s0899-9007(98)00040-9. Nutrition. 1998. PMID: 9646292 Review.
Here we present mechanistic data and results of epidemiologic studies on the relationship between antioxidant vitamin intake or biochemical status and the risk of cancer and cardiovascular diseases. ...All these studies indicate that a high dietary intake or high bl …
Here we present mechanistic data and results of epidemiologic studies on the relationship between antioxidant vitamin intake or bioch …
Dietary Supplement Use in Patients with Cardiovascular Disease.
Li S, Petraskova T, Stys N, Blue M, Stys T, Stys A. Li S, et al. S D Med. 2020 Feb;73(2):72-76. S D Med. 2020. PMID: 32135055
IMPORTANCE AND OBJECTIVE: Dietary supplements and herbs (called naturoceuticals) are commonly used by Americans, but little is known about their use in cardiovascular disease patient populations. The objective was to evaluate naturoceutical use in a sample population of …
IMPORTANCE AND OBJECTIVE: Dietary supplements and herbs (called naturoceuticals) are commonly used by Americans, but little is known about t …
Vitamin supplements and cardiovascular diseases.
Shaker R, Al-Ghamdi D, Razzaque M. Shaker R, et al. Saudi Med J. 2010 Jul;31(7):835-6; author reply 835. Saudi Med J. 2010. PMID: 20635024 No abstract available.
Background and rationale behind the SU.VI.MAX Study, a prevention trial using nutritional doses of a combination of antioxidant vitamins and minerals to reduce cardiovascular diseases and cancers. SUpplementation en VItamines et Mineraux AntioXydants Study.
Hercberg S, Galan P, Preziosi P, Roussel AM, Arnaud J, Richard MJ, Malvy D, Paul-Dauphin A, Briançon S, Favier A. Hercberg S, et al. Int J Vitam Nutr Res. 1998;68(1):3-20. Int J Vitam Nutr Res. 1998. PMID: 9503043 Review.
The "SUpplementation en VItamines et MinerauxAntioXydants" (SU.VI.MAX) study is a randomized double-blind, placebo-controlled, primary prevention trial designed to test the efficacy of daily supplementation with antioxidant vitamins (vitamin C, 120 mg; vit …
The "SUpplementation en VItamines et MinerauxAntioXydants" (SU.VI.MAX) study is a randomized double-blind, placebo-controlled, primar …
Effect of antioxidant vitamin supplementation on endothelial function in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials.
Montero D, Walther G, Stehouwer CD, Houben AJ, Beckman JA, Vinet A. Montero D, et al. Obes Rev. 2014 Feb;15(2):107-16. doi: 10.1111/obr.12114. Epub 2013 Oct 7. Obes Rev. 2014. PMID: 24118784 Review.
The aim of this study was to systematically review and quantify the effect of antioxidant vitamin supplementation on endothelial function in T2DM subjects. ...Ten randomized controlled trials comparing antioxidant vitamin-supplemented and control groups (overall n = …
The aim of this study was to systematically review and quantify the effect of antioxidant vitamin supplementation on endothelial func …
Vitamin D Attenuates Loss of Endothelial Biomarker Expression in Cardio-Endothelial Cells.
Lai CC, Juang WC, Sun GC, Tseng YK, Jhong RC, Tseng CJ, Wong TY, Cheng PW. Lai CC, et al. Int J Mol Sci. 2020 Mar 22;21(6):2196. doi: 10.3390/ijms21062196. Int J Mol Sci. 2020. PMID: 32235811 Free PMC article.
Vitamin D is associated with cardiovascular health through activating the vitamin D receptor that targets genes related to cardiovascular disease (CVD). ...Based on this study, the beneficial effect of vitamin D may be insignificant; however, fu …
Vitamin D is associated with cardiovascular health through activating the vitamin D receptor that targets genes related …
Effect of vitamin D deficiency in developed countries.
Hassan-Smith ZK, Hewison M, Gittoes NJ. Hassan-Smith ZK, et al. Br Med Bull. 2017 Jun 1;122(1):79-89. doi: 10.1093/bmb/ldx005. Br Med Bull. 2017. PMID: 28334220 Review.
INTRODUCTION: Vitamin D deficiency is common worldwide with adverse effects on skeletal health. ...AREAS OF CONTROVERSY: There is debate reflected in guidelines on optimal thresholds for circulating levels of vitamin D. Further studies are required to refine dosing …
INTRODUCTION: Vitamin D deficiency is common worldwide with adverse effects on skeletal health. ...AREAS OF CONTROVERSY: There is deb …
Therapeutic application of vitamin D receptor ligands: an updated patent review.
Takada I, Makishima M. Takada I, et al. Expert Opin Ther Pat. 2015;25(12):1373-83. doi: 10.1517/13543776.2015.1093113. Epub 2015 Sep 24. Expert Opin Ther Pat. 2015. PMID: 26402335 Review.
INTRODUCTION: The vitamin D receptor (VDR) is a promising drug target in the treatment of cancer, autoimmune disease, inflammation, infection and cardiovascular disease, as well as bone and mineral disorders. ...AREAS COVERED: We summarize recent patent activity reg …
INTRODUCTION: The vitamin D receptor (VDR) is a promising drug target in the treatment of cancer, autoimmune disease, inflammation, i …
Seaweed vitamins as nutraceuticals.
Škrovánková S. Škrovánková S. Adv Food Nutr Res. 2011;64:357-69. doi: 10.1016/B978-0-12-387669-0.00028-4. Adv Food Nutr Res. 2011. PMID: 22054961 Review.
Seaweeds are a good source of some water- (B(1), B(2), B(12), C) and fat-soluble (beta-carotene with vitamin A activity, vitamin E) vitamins. To ensure that the adequate intake of all vitamins is received in the diet, people (especially people on speci …
Seaweeds are a good source of some water- (B(1), B(2), B(12), C) and fat-soluble (beta-carotene with vitamin A activity, vitamin …
Vitamin C prevents zidovudine-induced NAD(P)H oxidase activation and hypertension in the rat.
Papparella I, Ceolotto G, Berto L, Cavalli M, Bova S, Cargnelli G, Ruga E, Milanesi O, Franco L, Mazzoni M, Petrelli L, Nussdorfer GG, Semplicini A. Papparella I, et al. Cardiovasc Res. 2007 Jan 15;73(2):432-8. doi: 10.1016/j.cardiores.2006.10.010. Epub 2006 Oct 20. Cardiovasc Res. 2007. PMID: 17123493
METHODS: Six adult Wistar Kyoto rats received AZT (1 mg/ml) in the drinking water for 8 months, six vitamin C (10 g/kg of food) and AZT, six vitamin C alone, and six served as controls. ...Vitamin C antagonizes these adverse effects of AZT in the cardiovas …
METHODS: Six adult Wistar Kyoto rats received AZT (1 mg/ml) in the drinking water for 8 months, six vitamin C (10 g/kg of food) and A …
Vitamin D deficiency: appropriate replenishment therapies and the effects of vitamin D toxicity.
Carlton S, Clopton D, Cappuzzo KA. Carlton S, et al. Consult Pharm. 2010 Mar;25(3):171-7. doi: 10.4140/TCP.n.2010.171. Consult Pharm. 2010. PMID: 20363711
In conjunction with the physician, the pharmacist discontinued vitamin D therapy and monitored levels.Vitamin D plays an integral role in the body's ability to absorb calcium and regulate calcium homeostasis. Further benefits have been reported regarding the …
In conjunction with the physician, the pharmacist discontinued vitamin D therapy and monitored levels.Vitamin D plays an integ …
A review of select vitamins and minerals used by postmenopausal women.
Dennehy C, Tsourounis C. Dennehy C, et al. Maturitas. 2010 Aug;66(4):370-80. doi: 10.1016/j.maturitas.2010.06.003. Epub 2010 Jun 26. Maturitas. 2010. PMID: 20580500 Review.
METHODS: Review of the relevant literature and results from recent clinical studies, as well as critical analyses of published systematic reviews and meta-analyses were obtained from PubMed and Cochrane Library of Reviews. Vitamin A, the B vitamins, vitamin C …
METHODS: Review of the relevant literature and results from recent clinical studies, as well as critical analyses of published systematic re …
Additive effect of homocysteine- and cholesterol-lowering therapy on endothelium-dependent vasodilation in patients with cardiovascular disease.
Wustmann K, Klaey M, Burow A, Shaw SG, Hess OM, Allemann Y. Wustmann K, et al. Cardiovasc Ther. 2012 Oct;30(5):277-86. doi: 10.1111/j.1755-5922.2011.00272.x. Epub 2011 Jul 31. Cardiovasc Ther. 2012. PMID: 21884007 Free article. Clinical Trial.
Thus, we evaluated the effect of rosuvastatin, B-group vitamins and their combination on endothelial function in high-risk cardiovascular patients. ...CONCLUSIONS: In conclusion, both treatments, rosuvastatin and B-group vitamin supplementation, improved endo …
Thus, we evaluated the effect of rosuvastatin, B-group vitamins and their combination on endothelial function in high-risk cardiov …
Can vitamin D slow down the progression of chronic kidney disease?
Shroff R, Wan M, Rees L. Shroff R, et al. Pediatr Nephrol. 2012 Dec;27(12):2167-73. doi: 10.1007/s00467-011-2071-y. Epub 2011 Dec 10. Pediatr Nephrol. 2012. PMID: 22160397 Review.
RAAS activation can reduce renal Klotho expression, and the Klotho-fibroblast growth factor 23 interaction may further reduce the production of active vitamin D. Results from both clinical and experimental studies suggest that vitamin D therapy is associated with a …
RAAS activation can reduce renal Klotho expression, and the Klotho-fibroblast growth factor 23 interaction may further reduce the production …
Vitamin K supplementation and progression of coronary artery calcium in older men and women.
Shea MK, O'Donnell CJ, Hoffmann U, Dallal GE, Dawson-Hughes B, Ordovas JM, Price PA, Williamson MK, Booth SL. Shea MK, et al. Am J Clin Nutr. 2009 Jun;89(6):1799-807. doi: 10.3945/ajcn.2008.27338. Epub 2009 Apr 22. Am J Clin Nutr. 2009. PMID: 19386744 Free PMC article. Clinical Trial.
BACKGROUND: Coronary artery calcification (CAC) is an independent predictor of cardiovascular disease. A preventive role for vitamin K in CAC progression has been proposed on the basis of the properties of matrix Gla protein (MGP) as a vitamin K-dependent cal …
BACKGROUND: Coronary artery calcification (CAC) is an independent predictor of cardiovascular disease. A preventive role for vitam …
Cardiovascular disease and vitamins. Concurrent correction of 'suboptimal' plasma antioxidant levels may, as important part of 'optimal' nutrition, help to prevent early stages of cardiovascular disease and cancer, respectively.
Gey KF. Gey KF. Bibl Nutr Dieta. 1995;(52):75-91. Bibl Nutr Dieta. 1995. PMID: 8779654 Review.
Material relative risks seem to disappear at 'optimal' antioxidant plasma levels in the order of > or = 50 micromol/l vitamin C, > or = 30 micromol/l lipid-standardized vitamin E (alpha-tocopherol/cholesterol ratio > or = 5.1-5.2), > or = 2.2 micromol/l …
Material relative risks seem to disappear at 'optimal' antioxidant plasma levels in the order of > or = 50 micromol/l vitamin C, & …
An evidence-based update on vitamins.
Orr KK, Hume AL. Orr KK, et al. Med Health R I. 2010 Apr;93(4):122-4. Med Health R I. 2010. PMID: 20486527 Review.
American adults take many types of vitamin supplements, despite limited evidence of their efficacy, especially in preventing chronic diseases such as cardiovascular disease and cancer. Supplements contain significant amounts of vitamins when consumed from mul …
American adults take many types of vitamin supplements, despite limited evidence of their efficacy, especially in preventing chronic …
Vitamins in dialysis: who, when and how much?
Kosmadakis G, Da Costa Correia E, Carceles O, Somda F, Aguilera D. Kosmadakis G, et al. Ren Fail. 2014 May;36(4):638-50. doi: 10.3109/0886022X.2014.882714. Epub 2014 Feb 6. Ren Fail. 2014. PMID: 24502653 Review.
Vitamins are playing a crucial role in multiple key metabolic pathways. ...Frequent treatment with antibiotics due to infections associated with the acquired uremia-related immunosuppression may derange the vitamin-producing intestinal microflora. Certain agents pre …
Vitamins are playing a crucial role in multiple key metabolic pathways. ...Frequent treatment with antibiotics due to infections asso …
Effects of vitamin supplements on clinical cardiovascular outcomes: Time to move on! - A comprehensive review.
Simsek B, Selte A, Egeli BH, Çakatay U. Simsek B, et al. Clin Nutr ESPEN. 2021 Apr;42:1-14. doi: 10.1016/j.clnesp.2021.02.014. Epub 2021 Feb 25. Clin Nutr ESPEN. 2021. PMID: 33745562 Review.
METHODS: A thorough PubMed search with the phrase: "Vitamin supplements and cardiovascular health" was performed. In the present review, focus was maintained on the evidence for the use of vitamin supplements in the prevention of major cardiovascular e …
METHODS: A thorough PubMed search with the phrase: "Vitamin supplements and cardiovascular health" was performed. In the prese …
The role of vitamin D in the human body with a special emphasis on dental issues: Literature review.
Krawiec M, Dominiak M. Krawiec M, et al. Dent Med Probl. 2018 Oct-Dec;55(4):419-424. doi: 10.17219/dmp/99051. Dent Med Probl. 2018. PMID: 30648367 Review.
It is produced in the human body and passes through many stages of synthesis. Vitamin D affects our body through the immune, muscular, nervous, and cardiovascular systems. ...A normal level of vitamin D is important in the treatment of periodontitis. More and …
It is produced in the human body and passes through many stages of synthesis. Vitamin D affects our body through the immune, muscular …
The noncalciotropic actions of vitamin D: recent clinical developments.
Maalouf NM. Maalouf NM. Curr Opin Nephrol Hypertens. 2008 Jul;17(4):408-15. doi: 10.1097/MNH.0b013e3283040c99. Curr Opin Nephrol Hypertens. 2008. PMID: 18660678 Free PMC article. Review.
RECENT FINDINGS: 1,25-Dihydroxyvitamin D stimulates the innate immune system, facilitating the clearance of infections such as tuberculosis. ...SUMMARY: The broad tissue distribution of the 25-hydroxyvitamin D 1alpha-hydroxylase enzyme and the vitamin D receptor est …
RECENT FINDINGS: 1,25-Dihydroxyvitamin D stimulates the innate immune system, facilitating the clearance of infections such as tuberc …
The molecular biology and pathophysiology of vascular calcification.
McCarty MF, DiNicolantonio JJ. McCarty MF, et al. Postgrad Med. 2014 Mar;126(2):54-64. doi: 10.3810/pgm.2014.03.2740. Postgrad Med. 2014. PMID: 24685968 Review.
Vascular calcification (VC), commonly encountered in renal failure, diabetes, and aging, is associated with a large increase in the risk for cardiovascular events and mortality. Calcification of the arterial media and of heart valves clearly plays a mediating role in this …
Vascular calcification (VC), commonly encountered in renal failure, diabetes, and aging, is associated with a large increase in the risk for …
Multivariate Analysis of Influence of Vitamin Intake on Vascular Function Parameters by Sex in the General Spanish Population: EVA Study.
Patino-Alonso MC, Gómez Sánchez M, Gómez Sánchez L, Alonso-Domínguez R, Sánchez-Aguadero N, Sánchez Salgado B, Rodríguez Sánchez E, García Ortiz L, Gómez-Marcos MA. Patino-Alonso MC, et al. Nutrients. 2020 Feb 28;12(3):643. doi: 10.3390/nu12030643. Nutrients. 2020. PMID: 32121178 Free PMC article.
The main objective of this study is to analyze the influence of vitamin intake on vascular function and as a secondary objective the adequacy of vitamin intake in a sample of the Spanish population without previous cardiovascular disease and analyze the diffe …
The main objective of this study is to analyze the influence of vitamin intake on vascular function and as a secondary objective the …
Vitamin activities in human portal, hepatic and femoral blood after vitamin ingestion.
Baker H, tenHove W, Baker E, Frank O. Baker H, et al. Int J Vitam Nutr Res. 1994;64(1):60-7. Int J Vitam Nutr Res. 1994. PMID: 8200751
All water-soluble vitamins proved elevated after vitamin ingestion principally in portal blood within 10 minutes as compared with hepatic and femoral blood. ...In contrast, ingestion of the fat-soluble vitamins A and E evoked no elevated vitamin activi …
All water-soluble vitamins proved elevated after vitamin ingestion principally in portal blood within 10 minutes as compared w …
Crosstalk between Vitamins A, B12, D, K, C, and E Status and Arterial Stiffness.
Mozos I, Stoian D, Luca CT. Mozos I, et al. Dis Markers. 2017;2017:8784971. doi: 10.1155/2017/8784971. Epub 2017 Jan 12. Dis Markers. 2017. PMID: 28167849 Free PMC article. Review.
The main mechanisms are related to antiatherogenic effects, improvement of endothelial function (vitamins A, C, D, and E) and metabolic profile (vitamins A, B12, C, D, and K), inhibition of the renin-angiotensin-aldosterone system (vitamin D), anti-inf …
The main mechanisms are related to antiatherogenic effects, improvement of endothelial function (vitamins A, C, D, and E) and metabol …
Vitamin nutrition in older adults.
Johnson KA, Bernard MA, Funderburg K. Johnson KA, et al. Clin Geriatr Med. 2002 Nov;18(4):773-99. doi: 10.1016/s0749-0690(02)00048-4. Clin Geriatr Med. 2002. PMID: 12608503 Review.
Laboratory testing is most helpful with respect to vitamin B12 and folate deficiency. Given the great value of clinical assessment, the low cost of vitamins, and the higher cost of laboratory testing, the authors do not recommend testing before instituting multivita …
Laboratory testing is most helpful with respect to vitamin B12 and folate deficiency. Given the great value of clinical assessment, t …
Effects of monthly dose and regular dosing of intravenous active vitamin D use on mortality among patients undergoing hemodialysis.
St Peter WL, Li S, Liu J, Gilbertson DT, Arneson TJ, Collins AJ. St Peter WL, et al. Pharmacotherapy. 2009 Feb;29(2):154-64. doi: 10.1592/phco.29.2.154. Pharmacotherapy. 2009. PMID: 19170585
STUDY OBJECTIVES: To determine if apparent protective mortality benefits of intravenous active vitamin D in patients undergoing hemodialysis extend across all groups defined by dialysis duration; if higher monthly dose and dosing regularity are associated with reduced mort …
STUDY OBJECTIVES: To determine if apparent protective mortality benefits of intravenous active vitamin D in patients undergoing hemod …
Vitamin supplementation: what the gastroenterologist needs to know.
Sharma N, Trope B, Lipman TO. Sharma N, et al. J Clin Gastroenterol. 2004 Nov-Dec;38(10):844-54. doi: 10.1097/00004836-200411000-00003. J Clin Gastroenterol. 2004. PMID: 15492599 Review.
BACKGROUND: The vitamin business is a multimillion dollar industry. Aggressive marketing strategies are used to make claims for the health benefits of these products. Observational studies suggest that people who consume vitamin supplements decrease their risks for …
BACKGROUND: The vitamin business is a multimillion dollar industry. Aggressive marketing strategies are used to make claims for the h …
The Role of Brain Barriers in Maintaining Brain Vitamin Levels.
Tiani KA, Stover PJ, Field MS. Tiani KA, et al. Annu Rev Nutr. 2019 Aug 21;39:147-173. doi: 10.1146/annurev-nutr-082018-124235. Epub 2019 May 31. Annu Rev Nutr. 2019. PMID: 31150592 Review.
It is increasingly recognized that tissue-specific nutrient deficiencies can exist in the absence of whole-body deficiency and that these deficiencies may result from disease or disease-related physiological processes. Brain and central nervous system tissues require adequ …
It is increasingly recognized that tissue-specific nutrient deficiencies can exist in the absence of whole-body deficiency and that these de …
[Enteral nutrition in neurological patients: is there enough vitamin D content in commonly used formulas?].
Botella Romero F, Alfaro Martínez JJ, Luna López V, Galicia Martín I; Grupo de Trabajo sobre Calcio y Vitamina D en Nutrición Enteral. Botella Romero F, et al. Nutr Hosp. 2012 Mar-Apr;27(2):341-8. doi: 10.1590/S0212-16112012000200003. Nutr Hosp. 2012. PMID: 22732955 Free article. Review. Spanish.
D and its effects on functional (falls, pain, quality of life) and cardiovascular goals (cardiovascular death, stroke, myocardial infarction, cardiovascular risk factors) have obtained as highlight data a clear reduction of falls and fractures, while the evid …
D and its effects on functional (falls, pain, quality of life) and cardiovascular goals (cardiovascular death, stroke, myocard …
Oral vitamin D, still a viable treatment option for psoriasis.
Kamangar F, Koo J, Heller M, Lee E, Bhutani T. Kamangar F, et al. J Dermatolog Treat. 2013 Aug;24(4):261-7. doi: 10.3109/09546634.2011.643219. Epub 2012 Jan 21. J Dermatolog Treat. 2013. PMID: 22103655 Review.
In addition, oral vitamin D improves psoriatic arthropathy. Moreover, vitamin D has been proven to have many health benefits such as prevention of cancer, improved cardiovascular health among many others. Psoriatic patients as a population are at increased ri …
In addition, oral vitamin D improves psoriatic arthropathy. Moreover, vitamin D has been proven to have many health benefits s …
The cardiovascular safety aspects of calcium supplementations: where does the truth lie? A personal perspective.
Pines A, Langer RD. Pines A, et al. Climacteric. 2015 Feb;18(1):6-10. doi: 10.3109/13697137.2014.947947. Epub 2014 Oct 16. Climacteric. 2015. PMID: 25318377 Review.
During the past years, an ongoing debate defies this paradigm, mainly because of a potential cardiovascular risk on the one hand, and uncertainty in regard to the extent of the beneficial bone effects on the other hand. ...We conclude that the best current evidence support …
During the past years, an ongoing debate defies this paradigm, mainly because of a potential cardiovascular risk on the one hand, and …
Folate in gastrointestinal health and disease.
Ponziani FR, Cazzato IA, Danese S, Fagiuoli S, Gionchetti P, Annicchiarico BE, D'Aversa F, Gasbarrini A. Ponziani FR, et al. Eur Rev Med Pharmacol Sci. 2012 Mar;16(3):376-85. Eur Rev Med Pharmacol Sci. 2012. PMID: 22530356 Review.
Further studies are needed to assess the role of folates in gastrointestinal tract diseases and in other gynecologic, neurologic, psychiatric, cardiovascular, ophthalmic and neoplastic diseases. Folates supplementation could be considered, in the future, as an effective co …
Further studies are needed to assess the role of folates in gastrointestinal tract diseases and in other gynecologic, neurologic, psychiatri …
Trends in use of herbal and nutritional supplements in cardiovascular patients.
Stys T, Stys A, Kelly P, Lawson W. Stys T, et al. Clin Cardiol. 2004 Feb;27(2):87-90. doi: 10.1002/clc.4960270208. Clin Cardiol. 2004. PMID: 14979626 Free PMC article.
Average low-density lipoprotein (106 vs. 108 mg/dl), average blood pressure (132/77 vs. 138/78 mmHg), and average hemoglobin (Hb)A1c (8.7 vs. 7.7%) showed no statistically significant differences between users and nonusers. Patients most commonly took multivitamins, vitamin …
Average low-density lipoprotein (106 vs. 108 mg/dl), average blood pressure (132/77 vs. 138/78 mmHg), and average hemoglobin (Hb)A1c (8.7 vs …
Vitamin therapy in the absence of obvious deficiency. What is the evidence?
Ovesen L. Ovesen L. Drugs. 1984 Feb;27(2):148-70. doi: 10.2165/00003495-198427020-00003. Drugs. 1984. PMID: 6230219 Review.
However, pharmacological doses of vitamins are claimed to be of value in a wide variety of conditions which have no, or only a superficial, resemblance to the classic vitamin deficiency syndromes. ...Evidence from such studies reveals a beneficial therapeutic effect …
However, pharmacological doses of vitamins are claimed to be of value in a wide variety of conditions which have no, or only a superf …
Should hypertensive patients take vitamin D?
Wuerzner G, Burnier M, Waeber B. Wuerzner G, et al. Curr Hypertens Rep. 2012 Aug;14(4):318-23. doi: 10.1007/s11906-012-0271-x. Curr Hypertens Rep. 2012. PMID: 22648128 Review.
The prevalence of both hypertension and vitamin D deficiency is high. The discovery of the vitamin D receptor and its possible effects on components of the cardiovascular system influencing blood pressure, such as the renin angiotensin system, t …
The prevalence of both hypertension and vitamin D deficiency is high. The discovery of the vitamin D receptor and its possible …
Protective effect of vitamin B5 (dexpanthenol) on cardiovascular damage induced by streptozocin in rats.
Demirci B, Demir O, Dost T, Birincioglu M. Demirci B, et al. Bratisl Lek Listy. 2014;115(4):190-6. doi: 10.4149/bll_2014_040. Bratisl Lek Listy. 2014. PMID: 24797592
OBJECTIVES: This study investigated whether Dexpanthenol (DEX) improves diabetic cardiovascular function and cardiac performance by regulating total oxidant and antioxidant status. ...
OBJECTIVES: This study investigated whether Dexpanthenol (DEX) improves diabetic cardiovascular function and cardiac performance by r …
Vitamins as homocysteine-lowering agents.
Brattström L. Brattström L. J Nutr. 1996 Apr;126(4 Suppl):1276S-80S. doi: 10.1093/jn/126.suppl_4.1276S. J Nutr. 1996. PMID: 8642470 Review.
Moderate hyperhomocysteinemia is, today, considered an established risk factor for cardiovascular disease. A graded dose-response relationship between plasma homocysteine concentration over its full range and cardiovascular risk strongly supports causality. ...Suppl …
Moderate hyperhomocysteinemia is, today, considered an established risk factor for cardiovascular disease. A graded dose-response rel …
Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using (18)F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design.
Peeters FECM, van Mourik MJW, Meex SJR, Bucerius J, Schalla SM, Gerretsen SC, Mihl C, Dweck MR, Schurgers LJ, Wildberger JE, Crijns HJGM, Kietselaer BLJH. Peeters FECM, et al. Nutrients. 2018 Mar 21;10(4):386. doi: 10.3390/nu10040386. Nutrients. 2018. PMID: 29561783 Free PMC article. Clinical Trial.
BASIK2 is a prospective, double-blind, randomized placebo-controlled trial investigating the effect of vitamin K2 (menaquinone-7;MK7) on imaging measurements of calcification in the bicuspid aortic valve (BAV) and calcific aortic valve stenosis (CAVS). ...Matrix Gla protei …
BASIK2 is a prospective, double-blind, randomized placebo-controlled trial investigating the effect of vitamin K2 (menaquinone-7;MK7) …
[Atherosclerosis].
Yamada N. Yamada N. Nihon Rinsho. 1999 Oct;57(10):2345-8. Nihon Rinsho. 1999. PMID: 10540884 Review. Japanese.
In the presence of excessive amounts of low-density lipoprotein (LDL), denatured LDL modified by oxidation or other reactions on the vascular wall is taken up by macrophages via scavenger receptors, resulting in the formation of foam cells and accumulation of cholesterol esters. …
In the presence of excessive amounts of low-density lipoprotein (LDL), denatured LDL modified by oxidation or other reactions on the vascula …
Effect of calcifediol treatment on cardiovascular outcomes in patients with acute coronary syndrome and percutaneous revascularization.
Navarro-Valverde C, Quesada-Gómez JM, Pérez-Cano R, Fernández-Palacín A, Pastor-Torres LF. Navarro-Valverde C, et al. Med Clin (Barc). 2018 Nov 9;151(9):345-352. doi: 10.1016/j.medcli.2017.11.033. Epub 2018 Jan 3. Med Clin (Barc). 2018. PMID: 29306481 Clinical Trial. English, Spanish.
BACKGROUND AND OBJECTIVES: Vitamin D deficiency has been consistently linked with cardiovascular diseases. ...The aim of this study was to evaluate the effect of treatment with calcifediol (25(OH)D(3)) on the cardiovascular system of patients with non- …
BACKGROUND AND OBJECTIVES: Vitamin D deficiency has been consistently linked with cardiovascular diseases. ...The aim of this …
[Vitamins and minerals with antioxidant properties and cardiometabolic risk: controversies and perspectives].
Catania AS, Barros CR, Ferreira SR. Catania AS, et al. Arq Bras Endocrinol Metabol. 2009 Jul;53(5):550-9. doi: 10.1590/s0004-27302009000500008. Arq Bras Endocrinol Metabol. 2009. PMID: 19768246 Review. Portuguese.
Vitamin E is found in the plasma and in the LDL particle, avoiding lipid peroxidation. ...Vitamin C participates in the vitamin E regeneration system, keeping the plasma's antioxidant potential. ...
Vitamin E is found in the plasma and in the LDL particle, avoiding lipid peroxidation. ...Vitamin C participates in the vit …
Use of vitamin D in chronic kidney disease patients.
Gal-Moscovici A, Sprague SM. Gal-Moscovici A, et al. Kidney Int. 2010 Jul;78(2):146-51. doi: 10.1038/ki.2010.113. Epub 2010 May 26. Kidney Int. 2010. PMID: 20505658 Free article. Review.
Recently, a potentially important role of vitamin D receptor activation (VDRa) in the survival of patients undergoing dialysis has been suggested. Beyond the effect on parathyroid hormone suppression, the pleiotropic effect of vitamin D has been associated with impr …
Recently, a potentially important role of vitamin D receptor activation (VDRa) in the survival of patients undergoing dialysis has be …
[Vitamins and oxidative stress].
Kodentsova VM, Vrzhesinskaia OA, Mazo VK. Kodentsova VM, et al. Vopr Pitan. 2013;82(3):11-8. Vopr Pitan. 2013. PMID: 24006747 Review. Russian.
Damaging effect on the antioxidant defense system is more pronounced compared to the stress response in animals with an isolated deficiency of vitamins C, A, E, B1 or B6 and the combined vitamins deficiency in the diet. Addition missing vitamin or v …
Damaging effect on the antioxidant defense system is more pronounced compared to the stress response in animals with an isolated defi …
[Vitamin D in the treatment of cardiorenal syndrome in patients with chronic nephropathy].
Kharlamov AN, Perrish AN, Gabiskiĭ IaL, Ronne Kh, Ivanova EIu. Kharlamov AN, et al. Kardiologiia. 2012;52(3):33-44. Kardiologiia. 2012. PMID: 22839442 Clinical Trial. Russian.
AIM: To determine place of vitamin D in prevention and treatment of cardiorenal syndrome (CRS) and chronic allograft nephropathy (CAN) in the aspect of myocardial and renal reparation. METHODS AND MATERIAL: In Russia and the Netherlands we included in a randomized placebo …
AIM: To determine place of vitamin D in prevention and treatment of cardiorenal syndrome (CRS) and chronic allograft nephropathy (CAN …
Vitamin D: a pleiotropic hormone.
Verstuyf A, Carmeliet G, Bouillon R, Mathieu C. Verstuyf A, et al. Kidney Int. 2010 Jul;78(2):140-5. doi: 10.1038/ki.2010.17. Epub 2010 Feb 24. Kidney Int. 2010. PMID: 20182414 Free article.
Upon binding of the ligand, the vitamin D receptor heterodimerizes with the retinoid X receptor and binds to vitamin D response elements in the promoter region of target genes to induce/repress their expression. ...Moreover, it has been demonstrated that 1,25(OH)(2) …
Upon binding of the ligand, the vitamin D receptor heterodimerizes with the retinoid X receptor and binds to vitamin D respons …
Hen's egg as a source of valuable biologically active substances.
Zdrojewicz Z, Herman M, Starostecka E. Zdrojewicz Z, et al. Postepy Hig Med Dosw (Online). 2016 Jul 6;70(0):751-9. doi: 10.5604/17322693.1208892. Postepy Hig Med Dosw (Online). 2016. PMID: 27383572 Free article. Review.
The aim of this article is to show current knowledge concerning valuable substances biologically active present in hen eggs and underline important nutritive role of hen eggs. Hen egg is a good source of nutrients such as proteins, vitamins (A, B2, B6, B12, D, E, K), miner …
The aim of this article is to show current knowledge concerning valuable substances biologically active present in hen eggs and underline im …
Effect of cholecalciferol supplementation on arterial stiffness: a systematic review and meta-analysis.
Upala S, Sanguankeo A, Congrete S, Jaruvongvanich V. Upala S, et al. Scand Cardiovasc J. 2016 Aug;50(4):230-5. doi: 10.3109/14017431.2016.1173226. Epub 2016 May 18. Scand Cardiovasc J. 2016. PMID: 27101968 Review.
BACKGROUND: Vitamin D deficiency increases risk of cardiovascular diseases, arterial stiffness, and endothelial dysfunction. ...CONCLUSIONS: There was no improvement of markers of arterial stiffness after vitamin D supplementation....
BACKGROUND: Vitamin D deficiency increases risk of cardiovascular diseases, arterial stiffness, and endothelial dysfunction. . …
Vitamins for the management of cardiovascular disease: a simple solution to a complex problem?
Lenhart SE, Nappi JM. Lenhart SE, et al. Pharmacotherapy. 1999 Dec;19(12):1400-14. doi: 10.1592/phco.19.18.1400.30892. Pharmacotherapy. 1999. PMID: 10600089 Review.
Attention is focusing on the relationship between homocysteine and cardiovascular disease and the role of vitamins in the management of this prevalent ailment. ...Vitamin supplements are not warranted in all patients with cardiovascular disease but may …
Attention is focusing on the relationship between homocysteine and cardiovascular disease and the role of vitamins in the mana …
Vitamin supplements: current controversies.
Reynolds RD. Reynolds RD. J Am Coll Nutr. 1994 Apr;13(2):118-26. doi: 10.1080/07315724.1994.10718383. J Am Coll Nutr. 1994. PMID: 8006292 Review.
Supplemental use of vitamins to prevent disease constitutes a major commercial enterprise in the United States. ...Recently published data have given strong support to several of the claims for major benefits of disease prevention, including that of cancer, cardiovascul …
Supplemental use of vitamins to prevent disease constitutes a major commercial enterprise in the United States. ...Recently published …
B Vitamins and Fatty Acids: What Do They Share with Small Vessel Disease-Related Dementia?
Moretti R, Peinkhofer C. Moretti R, et al. Int J Mol Sci. 2019 Nov 18;20(22):5797. doi: 10.3390/ijms20225797. Int J Mol Sci. 2019. PMID: 31752183 Free PMC article. Review.
Many studies have been written on vitamin supplementation, fatty acid, and dementia, but results are still under debate, and no definite conclusion has yet been drawn. Nevertheless, a significant amount of lab evidence confirms that vitamins of the B group are tight …
Many studies have been written on vitamin supplementation, fatty acid, and dementia, but results are still under debate, and no defin …
Efficacy of Vitamin D on Chronic Heart Failure Among Adults.
Chunbin W, Han W, Lin C. Chunbin W, et al. Int J Vitam Nutr Res. 2020 Jan;90(1-2):49-58. doi: 10.1024/0300-9831/a000487. Epub 2019 Apr 16. Int J Vitam Nutr Res. 2020. PMID: 30987550
Vitamin D deficiency commonly occurs in chronic heart failure. Whether additional vitamin D supplementation can be beneficial to adults with chronic heart failure remains unclear. ...Seven randomized controlled trials that investigated the effects of vitamin …
Vitamin D deficiency commonly occurs in chronic heart failure. Whether additional vitamin D supplementation can be beneficial …
[Advances in the knowledge of the use of micronutrients in artificial nutrition].
Muñoz García M, Pérez Menéndez-Conde C, Bermejo Vicedo T. Muñoz García M, et al. Nutr Hosp. 2011 Jan-Feb;26(1):37-47. Nutr Hosp. 2011. PMID: 21519728 Review. Spanish.
Micronutrients are defined as those compounds necessary for the adequate physiological status of the organism and that may be administered through the daily diet either enteral or parenteral. The term micronutrient encompasses the vitamins and oligoelements, also termed tr …
Micronutrients are defined as those compounds necessary for the adequate physiological status of the organism and that may be administered t …
Effects of dietary RRR α-tocopherol vs all-racemic α-tocopherol on health outcomes.
Ranard KM, Erdman JW Jr. Ranard KM, et al. Nutr Rev. 2018 Mar 1;76(3):141-153. doi: 10.1093/nutrit/nux067. Nutr Rev. 2018. PMID: 29301023 Review.
Of the 8 vitamin E analogues, RRR alpha-tocopherol likely has the greatest effect on health outcomes. ...To help close this gap, this review evaluates studies that investigated the effects of either RRR alpha-tocopherol or all-racemic alpha-tocopherol on health outcomes, a …
Of the 8 vitamin E analogues, RRR alpha-tocopherol likely has the greatest effect on health outcomes. ...To help close this gap, this …
Acute autonomic effects of vitamins and fats in male smokers.
Wright CI, Ruediger H, Kroner CI, Janssen BJ, Draijer R. Wright CI, et al. Eur J Clin Nutr. 2009 Feb;63(2):246-52. doi: 10.1038/sj.ejcn.1602912. Epub 2007 Sep 26. Eur J Clin Nutr. 2009. PMID: 17895912 Clinical Trial.
Plasma vitamin levels did not correlate with any cardiovascular parameters. ...CONCLUSIONS: In male smokers, circulating antioxidants had no effect on BRS and minor effects on the cardiovascular system were seen following acute fat and vitamin i …
Plasma vitamin levels did not correlate with any cardiovascular parameters. ...CONCLUSIONS: In male smokers, circulating antio …
A natural product telomerase activator as part of a health maintenance program: metabolic and cardiovascular response.
Harley CB, Liu W, Flom PL, Raffaele JM. Harley CB, et al. Rejuvenation Res. 2013 Oct;16(5):386-95. doi: 10.1089/rej.2013.1430. Rejuvenation Res. 2013. PMID: 23808324 Clinical Trial.
We conclude that in addition to apparent positive immune remodeling, PattonProtocol-1 may improve markers of metabolic, bone, and cardiovascular health....
We conclude that in addition to apparent positive immune remodeling, PattonProtocol-1 may improve markers of metabolic, bone, and cardiov …
Antioxidant therapy in critical care--is the microcirculation the primary target?
Biesalski HK, McGregor GP. Biesalski HK, et al. Crit Care Med. 2007 Sep;35(9 Suppl):S577-83. doi: 10.1097/01.CCM.0000278598.95294.C5. Crit Care Med. 2007. PMID: 17713412 Review.
Parenteral high-dose vitamin C inhibits endotoxin-induced endothelial dysfunction and vasohyporeactivity in humans and reverses sepsis-induced suppression of microcirculatory control in rodents. In severe burn injury, in both animals and patients, parenteral high-dose v …
Parenteral high-dose vitamin C inhibits endotoxin-induced endothelial dysfunction and vasohyporeactivity in humans and reverses sepsi …
Vitamin D therapy for chronic kidney disease.
Bhan I, Thadhani R. Bhan I, et al. Semin Nephrol. 2009 Jan;29(1):85-93. doi: 10.1016/j.semnephrol.2008.10.010. Semin Nephrol. 2009. PMID: 19121478 Review.
Vitamin D has played a central role in the nephrologist's armamentarium, with active vitamin D analogues enjoying broad use for treatment of secondary hyperparathyroidism. Increasing data are now coming to light about the broader biological actions of vita …
Vitamin D has played a central role in the nephrologist's armamentarium, with active vitamin D analogues enjoying broad …
Vitamin K2. Monograph.
[No authors listed] [No authors listed] Altern Med Rev. 2009 Sep;14(3):284-93. Altern Med Rev. 2009. PMID: 19803553 Free article. Review. No abstract available.
Adverse myocardial effects of B-vitamin therapy in subjects with chronic kidney disease and hyperhomocysteinaemia.
Rafeq Z, Roh JD, Guarino P, Kaufman J, Joseph J. Rafeq Z, et al. Nutr Metab Cardiovasc Dis. 2013 Sep;23(9):836-42. doi: 10.1016/j.numecd.2012.07.002. Epub 2012 Aug 16. Nutr Metab Cardiovasc Dis. 2013. PMID: 22902185 Clinical Trial.
HCY levels were inversely correlated with diastolic function (R=-0.21; p=0.038). Vitamin therapy resulted in a significant increase in left atrial size (+0.150.8 cm vs. -0.130.07 cm; p=0.0095). ...These findings suggest that high-dose B vitamin therapy may be harmfu …
HCY levels were inversely correlated with diastolic function (R=-0.21; p=0.038). Vitamin therapy resulted in a significant increase i …
Human nutrition and blood pressure regulation: an integrated approach.
McCarron DA, Henry HJ, Morris CD. McCarron DA, et al. Hypertension. 1982 Sep-Oct;4(5 Pt 2):III2-13. doi: 10.1161/01.hyp.4.5_pt_2.iii2. Hypertension. 1982. PMID: 7049930 Review.
This review highlights the complex interactions that constitute the disciplines of nutrition and cardiovascular physiology. Nutritional factors have long been considered as critical in the pathogenesis of human hypertension. Theoretical and established contributions of var …
This review highlights the complex interactions that constitute the disciplines of nutrition and cardiovascular physiology. Nutrition …
Antioxidant vitamins and cardiovascular disease.
Katan MB, Zock PL. Katan MB, et al. Pharmacol Res. 1999 Sep;40(3):209-10. doi: 10.1006/phrs.1999.0515. Pharmacol Res. 1999. PMID: 10479464 No abstract available.
Mechanism of action of vitamin C in sepsis: ascorbate modulates redox signaling in endothelium.
Wilson JX. Wilson JX. Biofactors. 2009 Jan-Feb;35(1):5-13. doi: 10.1002/biof.7. Biofactors. 2009. PMID: 19319840 Free PMC article. Review.
Circulating levels of vitamin C (ascorbate) are low in patients with sepsis. Parenteral administration of ascorbate raises plasma and tissue concentrations of the vitamin and may decrease morbidity. ...
Circulating levels of vitamin C (ascorbate) are low in patients with sepsis. Parenteral administration of ascorbate raises plasma and …
Naturoceutical agents in the management of cardiovascular disease.
Hermann DD. Hermann DD. Am J Cardiovasc Drugs. 2002;2(3):173-96. doi: 10.2165/00129784-200202030-00005. Am J Cardiovasc Drugs. 2002. PMID: 14727980 Review.
These are the primary and secondary prevention of cardiovascular diseases and the treatment of diagnosed disorders such as heart failure, angina pectoris or arrhythmia. ...Thus, the role of naturoceutical agents in the integrative management of cardiovascular disord …
These are the primary and secondary prevention of cardiovascular diseases and the treatment of diagnosed disorders such as heart fail …
Strategies to reduce oxidative stress in cardiovascular disease.
Hamilton CA, Miller WH, Al-Benna S, Brosnan MJ, Drummond RD, McBride MW, Dominiczak AF. Hamilton CA, et al. Clin Sci (Lond). 2004 Mar;106(3):219-34. doi: 10.1042/CS20030379. Clin Sci (Lond). 2004. PMID: 14733610 Review.
A multitude of studies in experimental animals, together with clinical data, provide evidence that increased production of ROS (reactive oxygen species) are involved in the development and progression of cardiovascular disease. As ROS appear to have a critical role in athe …
A multitude of studies in experimental animals, together with clinical data, provide evidence that increased production of ROS (reactive oxy …
Vitamin A supplementation according to zinc status on oxidative stress levels in cardiac surgery patients.
Matos A, Souza G, Moreira V, Luna M, Ramalho A. Matos A, et al. Nutr Hosp. 2018 Jun 22;35(4):767-773. doi: 10.20960/nh.1666. Nutr Hosp. 2018. PMID: 30070862 Free article.
In this context, vitamin A and zinc serves an important function in the immunological system because it plays a role in fighting oxidative stress. ...METHODS: a control group (G1) and a vitamin A intervention group (G2- 5,000 IU of vitamin A daily) wer …
In this context, vitamin A and zinc serves an important function in the immunological system because it plays a role in fighti …
Vitamin D supplementation for the improvement of vascular function in patients with chronic kidney disease: a meta-analysis of randomized controlled trials.
Dou D, Yang B, Gan H, Xie D, Lei H, Ye N. Dou D, et al. Int Urol Nephrol. 2019 May;51(5):851-858. doi: 10.1007/s11255-019-02088-3. Epub 2019 Feb 8. Int Urol Nephrol. 2019. PMID: 30737643
In the 1 ug paricalcitol group, there was no significant difference between the two groups. For pulse wave velocity (PWV), vitamin D significantly decreased PWV compared with the placebo (WMD - 0.93 m/s; 95% CI - 1.71 to - 0.15, p = 0.02; without significant heterog …
In the 1 ug paricalcitol group, there was no significant difference between the two groups. For pulse wave velocity (PWV), vitamin D …
Vitamin B12 supplementation improves heart rate variability in healthy elderly Indian subjects.
Sucharita S, Thomas T, Antony B, Vaz M. Sucharita S, et al. Auton Neurosci. 2012 May 21;168(1-2):66-71. doi: 10.1016/j.autneu.2011.12.002. Epub 2012 Jan 5. Auton Neurosci. 2012. PMID: 22226502
While vitamin B(12) deficiency is global, data in elderly Indians are lacking. ...They underwent blood sampling, anthropometry, HRV and nerve conduction assessment. Subjects were classified based on vitamin B(12) level (148 pmol/L) into deplete vitamin B(12) …
While vitamin B(12) deficiency is global, data in elderly Indians are lacking. ...They underwent blood sampling, anthropometry, HRV a …
[Vitamin C+sodium bicarbonate versus sodium bicarbonate alone in preventing contrast-induced nephropathy].
Laroussi L, Triki M, Ibn Elhaj Z, Ben Halima A, Boukhris M, Ben Amara W, Keskes H, Kraiem S, Lahidheb D, Marrakchi S, Kammoun I, Addad F, Kachboura S. Laroussi L, et al. Ann Cardiol Angeiol (Paris). 2017 Sep;66(4):190-196. doi: 10.1016/j.ancard.2017.02.002. Epub 2017 May 25. Ann Cardiol Angeiol (Paris). 2017. PMID: 28551197 Clinical Trial. French.
RESULTS: The mean age of our study population was 60.89.3 years (36-83 years). The two study groups were comparable in terms of cardiovascular risk factors, concomitant medication, and baseline serum creatinine. The CIN incidence was 6.3% in the vitamin C group and …
RESULTS: The mean age of our study population was 60.89.3 years (36-83 years). The two study groups were comparable in terms of cardiovas …
Antioxidant vitamins and blood pressure.
Czernichow S, Blacher J, Hercberg S. Czernichow S, et al. Curr Hypertens Rep. 2004 Feb;6(1):27-30. doi: 10.1007/s11906-004-0007-7. Curr Hypertens Rep. 2004. PMID: 14972086 Review.
This process can be stopped by antioxidants such as beta-carotene, vitamin C, or vitamin E, which will inactivate the effects of free radicals. Although antioxidant vitamins have not been proven to prevent cardiovascular diseases through the modulation …
This process can be stopped by antioxidants such as beta-carotene, vitamin C, or vitamin E, which will inactivate the effects …
[Prevention of cardiovascular and degenerative diseases: I. Aspirin, statins, or vitamins?].
Martin-Du Pan RC. Martin-Du Pan RC. Rev Med Suisse Romande. 2003 Mar;123(3):175-81. Rev Med Suisse Romande. 2003. PMID: 15095704 Review. French.
Coronary syndromes are induced by atherosclerosis which results from lipid deposit as well as inflammatory cells in vascular walls triggered by oxidative modification of LDL cholesterol. Treatment with antioxidant vitamins (vitamin C and E) has no evident effect on …
Coronary syndromes are induced by atherosclerosis which results from lipid deposit as well as inflammatory cells in vascular walls triggered …
Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review.
Dietrich M, Traber MG, Jacques PF, Cross CE, Hu Y, Block G. Dietrich M, et al. J Am Coll Nutr. 2006 Aug;25(4):292-9. doi: 10.1080/07315724.2006.10719538. J Am Coll Nutr. 2006. PMID: 16943450 Review.
Vitamin E consists of a group of eight isomers, four tocopherols (alpha-, beta-, gamma-, delta-tocopherol) and four tocotrienols (alpha-, beta-, gamma-, delta-tocotrienol). While extensive literature has been published on the potential health benefits of alpha-tocopherol, …
Vitamin E consists of a group of eight isomers, four tocopherols (alpha-, beta-, gamma-, delta-tocopherol) and four tocotrienols (alp …
Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications.
Münzel T, Gori T, Keaney JF Jr, Maack C, Daiber A. Münzel T, et al. Eur Heart J. 2015 Oct 7;36(38):2555-64. doi: 10.1093/eurheartj/ehv305. Epub 2015 Jul 4. Eur Heart J. 2015. PMID: 26142467 Free PMC article. Review.
Systolic and diastolic myocardial dysfunction has been demonstrated to be associated with an activation of the circulating and local renin-angiotensin-aldosterone system (RAAS), and with a subsequent inappropriately increased production of reactive oxygen species (ROS). .. …
Systolic and diastolic myocardial dysfunction has been demonstrated to be associated with an activation of the circulating and local renin-a …
Treating endothelial dysfunction with vitamin D in chronic kidney disease: a meta-analysis.
Lundwall K, Jacobson SH, Jörneskog G, Spaak J. Lundwall K, et al. BMC Nephrol. 2018 Sep 25;19(1):247. doi: 10.1186/s12882-018-1042-y. BMC Nephrol. 2018. PMID: 30253741 Free PMC article.
BACKGROUND: Vitamin D deficiency is common in patients with chronic kidney disease (CKD), and is associated with endothelial dysfunction and cardiovascular disease. ...METHODS: PubMed/Medline, Web of Science, Embase and Cochrane trials and reviews were searched syst …
BACKGROUND: Vitamin D deficiency is common in patients with chronic kidney disease (CKD), and is associated with endothelial dysfunct …
Dietary and circulating antioxidant vitamins in relation to carotid plaques in middle-aged women.
Iannuzzi A, Celentano E, Panico S, Galasso R, Covetti G, Sacchetti L, Zarrilli F, De Michele M, Rubba P. Iannuzzi A, et al. Am J Clin Nutr. 2002 Sep;76(3):582-7. doi: 10.1093/ajcn/76.3.582. Am J Clin Nutr. 2002. PMID: 12198003
The participants answered a food-frequency questionnaire, and their plasma concentrations of vitamin E, vitamin A, and carotenoids were measured. None of the women took vitamin supplements. ...This association was independent of other cardiovascular ri …
The participants answered a food-frequency questionnaire, and their plasma concentrations of vitamin E, vitamin A, and caroten …
Vitamins in "malattie evolutive".
Hanck AB. Hanck AB. Acta Vitaminol Enzymol. 1980;2(5-6):179-85. Acta Vitaminol Enzymol. 1980. PMID: 7027765 Clinical Trial.
Examples of the preventive use of vitamins in certain development phases are the prophylactic administration of vitamin E in premature and new-born babies as protection against retrolental fibroplasia, vitamin K against haemorrhage and vitamin D agains …
Examples of the preventive use of vitamins in certain development phases are the prophylactic administration of vitamin E in p …
Vitamin C intake attenuates the degree of experimental atherosclerosis induced by periodontitis in the rat by decreasing oxidative stress.
Ekuni D, Tomofuji T, Sanbe T, Irie K, Azuma T, Maruyama T, Tamaki N, Murakami J, Kokeguchi S, Yamamoto T. Ekuni D, et al. Arch Oral Biol. 2009 May;54(5):495-502. doi: 10.1016/j.archoralbio.2009.02.006. Epub 2009 Mar 17. Arch Oral Biol. 2009. PMID: 19296928
Since vitamin C has been suggested to limit oxidative damage, we hypothesized that vitamin C intake may reduce endothelial oxidative stress induced by periodontitis in the aorta. ...In the vitamin C group, rats were given distilled water containing 1 g/L v …
Since vitamin C has been suggested to limit oxidative damage, we hypothesized that vitamin C intake may reduce endothelial oxi …
Hypertension and insulin resistance.
Whaley-Connell A, Sowers JR. Whaley-Connell A, et al. Hypertension. 2009 Sep;54(3):462-4. doi: 10.1161/HYPERTENSIONAHA.109.134460. Epub 2009 Jul 27. Hypertension. 2009. PMID: 19635987 Free PMC article. No abstract available.
[Effect mechanism of Hcy on damage of BBB and the intervention of the compounded vitamin in rat].
Peng H, Cheng H, Xing HY, Li G, Yu FQ. Peng H, et al. Zhonghua Yi Xue Za Zhi. 2010 Jun 15;90(23):1642-4. Zhonghua Yi Xue Za Zhi. 2010. PMID: 20979757 Chinese.
OBJECTIVE: To study the effect of homocysteine (Hcy) on the damage of blood-brain barrier, and the intervention of the compounded vitamin in rat. METHODS: 54 normal male SD rats were randomly distributed into three groups: (1) Control group; (2) Model group; and (3) Interv …
OBJECTIVE: To study the effect of homocysteine (Hcy) on the damage of blood-brain barrier, and the intervention of the compounded vitamin …
Effect of multivitamin supplementation on the homocysteine and methylmalonic acid blood concentrations in women over the age of 60 years.
Wolters M, Hermann S, Hahn A. Wolters M, et al. Eur J Nutr. 2005 Mar;44(3):183-92. doi: 10.1007/s00394-004-0510-2. Epub 2004 May 19. Eur J Nutr. 2005. PMID: 15309436 Clinical Trial.
BACKGROUND: Deficiency of folic acid, vitamin B(6) and/or vitamin B(12) can result in elevated total plasma homocysteine concentrations (tHcy), which are considered to be a risk factor for vascular disease. Studies have shown that supplementation of the three vit …
BACKGROUND: Deficiency of folic acid, vitamin B(6) and/or vitamin B(12) can result in elevated total plasma homocysteine conce …
Effects of prenatal vitamins A, E, and C on the hypoplastic hearts of fetal rats with diaphragmatic hernia.
González-Reyes S, Martínez L, Tovar JA. González-Reyes S, et al. J Pediatr Surg. 2005 Aug;40(8):1269-74. doi: 10.1016/j.jpedsurg.2005.05.009. J Pediatr Surg. 2005. PMID: 16080930
This study aims at testing the hypothesis that vitamin A and other antioxidant vitamins, such as E and C, could improve myocardial development even when administered late in gestation, a likely useful period for prenatal medication. MATERIAL AND METHODS: Time-mated …
This study aims at testing the hypothesis that vitamin A and other antioxidant vitamins, such as E and C, could improve myocar …
Natural bioactive substances in milk and colostrum: effects on the arterial blood pressure system.
Groziak SM, Miller GD. Groziak SM, et al. Br J Nutr. 2000 Nov;84 Suppl 1:S119-25. doi: 10.1017/s0007114500002348. Br J Nutr. 2000. PMID: 11242456 Review.
High blood pressure is a significant public health problem worldwide which is associated with increased risk of cardiovascular disease, stroke, and renal disease. The development of this disease is influenced by genetic and environmental factors. ...
High blood pressure is a significant public health problem worldwide which is associated with increased risk of cardiovascular diseas …
Herbal therapies and cardiac side effects.
Flattery M. Flattery M. Prog Cardiovasc Nurs. 2008 Fall;23(4):187-90. doi: 10.1111/j.1751-7117.2008.00014.x. Prog Cardiovasc Nurs. 2008. PMID: 19067984 Review. No abstract available.
Effect of high-dose oral cholecalciferol on cardiac mechanics in children with chronic kidney disease.
Deveci M, Aytaç MB, Altun G, Kayabey Ö, Babaoğlu K. Deveci M, et al. Cardiol Young. 2017 Nov;27(9):1807-1814. doi: 10.1017/S1047951117001482. Epub 2017 Aug 3. Cardiol Young. 2017. PMID: 28770692
Cardiovascular factors are an important cause of mortality in chronic kidney disease, and vitamin-D deficiency is common in this patient population. ...Initial longitudinal and radial strain as well as strain rate values of the left ventricle were significantly lowe …
Cardiovascular factors are an important cause of mortality in chronic kidney disease, and vitamin-D deficiency is common in th …
In subtotally nephrectomized rats 22-oxacalcitriol suppresses parathyroid hormone with less risk of cardiovascular calcification or deterioration of residual renal function than 1,25(OH)2 vitamin D3.
Hirata M, Katsumata K, Endo K, Fukushima N, Ohkawa H, Fukagawa M. Hirata M, et al. Nephrol Dial Transplant. 2003 Sep;18(9):1770-6. doi: 10.1093/ndt/gfg296. Nephrol Dial Transplant. 2003. PMID: 12937223
BACKGROUND: Although it effectively suppresses parathyroid hormone (PTH) secretion, vitamin D [1,25(OH)(2)D(3)] therapy often causes tissue calcification over the long term. In patients on chronic dialysis, cardiovascular calcification is clearly linked to an unfavo …
BACKGROUND: Although it effectively suppresses parathyroid hormone (PTH) secretion, vitamin D [1,25(OH)(2)D(3)] therapy often causes …
Study of Protein Oxidative Stress, Antioxidant Vitamins and Inflammation in Patients Undergoing either Hemodialysis or Peritoneal Dialysis.
Marques de Mattos A, Afonso Jordão A, Abrão Cardeal da Costa J, Garcia Chiarello P. Marques de Mattos A, et al. Int J Vitam Nutr Res. 2014;84(5-6):261-8. doi: 10.1024/0300-9831/a000212. Int J Vitam Nutr Res. 2014. PMID: 26255547
Elucidating this influence could provide novel therapy concepts for cardiovascular diseases. AIM: To compare protein OS, antioxidant vitamins and inflammation in patients undergoing either hemodialysis (HD) or peritoneal dialysis (PD). ...Hemodialysis probably exace …
Elucidating this influence could provide novel therapy concepts for cardiovascular diseases. AIM: To compare protein OS, antioxidant …
Bioavailability of α-tocopherol stereoisomers in lambs depends on dietary doses of all-rac- or RRR-α-tocopheryl acetate.
Leal LN, Jensen SK, Bello JM, Den Hartog LA, Hendriks WH, Martín-Tereso J. Leal LN, et al. Animal. 2019 Sep;13(9):1874-1882. doi: 10.1017/S1751731118003373. Epub 2018 Dec 27. Animal. 2019. PMID: 30587272 Free article.
When supplementing lamb diets with vitamin E, an equivalence factor of 1.36 is used to discriminate between RRR-alpha-tocopheryl acetate and all-rac-alpha-tocopheryl acetate. ...Within 20 min after slaughter samples of muscle, heart, liver, brain and spleen were frozen at …
When supplementing lamb diets with vitamin E, an equivalence factor of 1.36 is used to discriminate between RRR-alpha-tocopheryl acet …
[Antioxidant vitamin supplementation in the prevention of cardiovascular disease].
Yuen B, Furrer L, Ballmer PE. Yuen B, et al. Ther Umsch. 2005 Sep;62(9):615-8. doi: 10.1024/0040-5930.62.9.615. Ther Umsch. 2005. PMID: 16218497 Review. German.
Various observational epidemiological studies have suggested that antioxidant vitamin intake is associated with reduced cardiovascular morbidity and mortality. Also, experimental studies in animals have demonstrated that antioxidant vitamins slow the progress …
Various observational epidemiological studies have suggested that antioxidant vitamin intake is associated with reduced cardiovasc …