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Page 1
Vitamin D contributes to mast cell stabilization.
Liu ZQ, Li XX, Qiu SQ, Yu Y, Li MG, Yang LT, Li LJ, Wang S, Zheng PY, Liu ZG, Yang PC. Liu ZQ, et al. Allergy. 2017 Aug;72(8):1184-1192. doi: 10.1111/all.13110. Epub 2017 Jan 17. Allergy. 2017. PMID: 27998003
The mechanism of mast cell stabilization is not fully understood. Cumulative reports indicate that vitamin D (VitD) contributes to the homeostasis in the body. This study tests a hypothesis that VitD is required in the maintenance of the stability of …
The mechanism of mast cell stabilization is not fully understood. Cumulative reports indicate that vitamin D (Vi …
Vitamin D Influences the Activity of Mast Cells in Allergic Manifestations and Potentiates Their Effector Functions against Pathogens.
Mehrani Y, Morovati S, Tieu S, Karimi N, Javadi H, Vanderkamp S, Sarmadi S, Tajik T, Kakish JE, Bridle BW, Karimi K. Mehrani Y, et al. Cells. 2023 Sep 14;12(18):2271. doi: 10.3390/cells12182271. Cells. 2023. PMID: 37759494 Free PMC article. Review.
Mast cells (MCs) are abundant at sites exposed to the external environment and pathogens. ...Vitamin D binds to its receptor, called the vitamin D receptor (VDR), which is present in almost all immune system cells. ...
Mast cells (MCs) are abundant at sites exposed to the external environment and pathogens. ...Vitamin D binds to …
Mast Cells and Vitamin D Status: A Clinical and Biological Link in the Onset of Allergy and Bone Diseases.
Murdaca G, Allegra A, Tonacci A, Musolino C, Ricciardi L, Gangemi S. Murdaca G, et al. Biomedicines. 2022 Aug 3;10(8):1877. doi: 10.3390/biomedicines10081877. Biomedicines. 2022. PMID: 36009422 Free PMC article. Review.
Vitamin D is recognized to induce changes in bone metabolism, but it is also able to influence immune response, suppressing mast cell activation and IgE synthesis from B cells and increasing the number of dendritic cells and IL-10-generat …
Vitamin D is recognized to induce changes in bone metabolism, but it is also able to influence immune response, suppressing …
Vitamin D suppress the production of vascular endothelial growth factor in mast cell by inhibiting PI3K/Akt/p38 MAPK/HIF-1alpha pathway in chronic spontaneous urticaria.
Zhao JW, Ping JD, Wang YF, Liu XN, Li N, Hu ZL, Ming L. Zhao JW, et al. Clin Immunol. 2020 Jun;215:108444. doi: 10.1016/j.clim.2020.108444. Epub 2020 Apr 25. Clin Immunol. 2020. PMID: 32339669 Free article.
Mast cells play a significant role in urticaria pathogenesis. It's evidenced that vitamin D has positive impact in chronic spontaneous urticaria (CSU) recently, but underlying mechanisms remain unclear. ...Our results indicated that sera of CSU patient …
Mast cells play a significant role in urticaria pathogenesis. It's evidenced that vitamin D has positive impact …
Non-IgE mediated mast cell activation.
Redegeld FA, Yu Y, Kumari S, Charles N, Blank U. Redegeld FA, et al. Immunol Rev. 2018 Mar;282(1):87-113. doi: 10.1111/imr.12629. Immunol Rev. 2018. PMID: 29431205 Review.
Mast cells (MCs) are innate immune cells that are scattered in tissues throughout the organism being particularly abundant at sites exposed to the environment such as the skin and mucosal surfaces. ...This allows them to organize the ensuing innate immune and …
Mast cells (MCs) are innate immune cells that are scattered in tissues throughout the organism being particularly abund …
Evidence that vitamin D(3) promotes mast cell-dependent reduction of chronic UVB-induced skin pathology in mice.
Biggs L, Yu C, Fedoric B, Lopez AF, Galli SJ, Grimbaldeston MA. Biggs L, et al. J Exp Med. 2010 Mar 15;207(3):455-63. doi: 10.1084/jem.20091725. Epub 2010 Mar 1. J Exp Med. 2010. PMID: 20194632 Free PMC article.
We now show that 1alpha,25(OH)(2)D(3) can up-regulate IL-10 mRNA expression and induce IL-10 secretion in mouse mast cells in vitro. To investigate the roles of 1alpha,25(OH)(2)D(3) and mast cell vitamin D receptor (VDR) expression in chr …
We now show that 1alpha,25(OH)(2)D(3) can up-regulate IL-10 mRNA expression and induce IL-10 secretion in mouse mast cells in …
Vitamin D(3) signalling to mast cells: A new regulatory axis.
Yu C, Fedoric B, Anderson PH, Lopez AF, Grimbaldeston MA. Yu C, et al. Int J Biochem Cell Biol. 2011 Jan;43(1):41-6. doi: 10.1016/j.biocel.2010.10.011. Epub 2010 Oct 23. Int J Biochem Cell Biol. 2011. PMID: 20974277 Review.
Recent studies have uncovered an immunoregulatory interaction between vitamin D(3) and dermal mast cells for optimal protection against pathogenic outcomes associated with chronic UVB irradiation of the skin. ...This review will focus on the relative i …
Recent studies have uncovered an immunoregulatory interaction between vitamin D(3) and dermal mast cells for opt …
Vitamin D in Asthma: Mechanisms of Action and Considerations for Clinical Trials.
Pfeffer PE, Hawrylowicz CM. Pfeffer PE, et al. Chest. 2018 May;153(5):1229-1239. doi: 10.1016/j.chest.2017.09.005. Epub 2017 Sep 18. Chest. 2018. PMID: 28923762 Review.
There is increasing interest in the therapeutic utility of vitamin D in asthma, which is supported by a significant body of evidence on epidemiologic associations between vitamin D insufficiency and worse asthma control. In support of a causal relation …
There is increasing interest in the therapeutic utility of vitamin D in asthma, which is supported by a significant body of ev …
Mechanisms of vitamin D3 metabolite repression of IgE-dependent mast cell activation.
Yip KH, Kolesnikoff N, Yu C, Hauschild N, Taing H, Biggs L, Goltzman D, Gregory PA, Anderson PH, Samuel MS, Galli SJ, Lopez AF, Grimbaldeston MA. Yip KH, et al. J Allergy Clin Immunol. 2014 May;133(5):1356-64, 1364.e1-14. doi: 10.1016/j.jaci.2013.11.030. Epub 2014 Jan 22. J Allergy Clin Immunol. 2014. PMID: 24461581 Free PMC article.
Although mast cells express the vitamin D receptor (VDR), it is not clear to what extent 1alpha,25-dihydroxyvitamin D3 (1alpha,25[OH]2D3) or its predominant inactive precursor metabolite in the circulation, 25-hydroxyvitamin D3 (25OHD3), can influence …
Although mast cells express the vitamin D receptor (VDR), it is not clear to what extent 1alpha,25-dihydroxyvita …
Vitamin D and alopecia areata: possible roles in pathogenesis and potential implications for therapy.
Lin X, Meng X, Song Z. Lin X, et al. Am J Transl Res. 2019 Sep 15;11(9):5285-5300. eCollection 2019. Am J Transl Res. 2019. PMID: 31632510 Free PMC article. Review.
This article reviews the current literature and discusses the possible roles of vitamin D in the pathogenesis of alopecia areata in the context of (1) loss of immune privilege in hair follicle, (2) autoreactive effector T cells and mast cells, ( …
This article reviews the current literature and discusses the possible roles of vitamin D in the pathogenesis of alopecia area …
126 results