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Vitamin D3 (cholecalciferol) is more efficacious than Vitamin D2 (ergocalciferol) at regulating calcium absorption and bone quality in rats.
Dutta S, Sudharma AA, Aboo S, Jatavath S, Siginam S, Patil PB, Vadakattu SS, Surekha MV, Reddy GB, Ismail A. Dutta S, et al. J Steroid Biochem Mol Biol. 2025 Nov;254:106837. doi: 10.1016/j.jsbmb.2025.106837. Epub 2025 Jul 23. J Steroid Biochem Mol Biol. 2025. PMID: 40712802
Differential efficacy of vitamin D2 (D2) versus vitamin D3 (D3) in improving classical functions in target organs remain incompletely understood. ...Weanling male Sprague-Dawley rats were subjected to a depletion-repletion study de …
Differential efficacy of vitamin D2 (D2) versus vitamin D3 (D3) in improving classical func …
Vitamin D2 versus vitamin D3 supplementation in hemodialysis patients: a comparative pilot study.
Daroux M, Shenouda M, Bacri JL, Lemaitre V, Vanhille P, Bataille P. Daroux M, et al. J Nephrol. 2013 Jan-Feb;26(1):152-7. doi: 10.5301/jn.5000123. J Nephrol. 2013. PMID: 22641581 Clinical Trial.
BACKGROUND: In patients with chronic kidney disease, vitamin D insufficiency is highly prevalent. It can be corrected by supplementation with either vitamin D(2) or vitamin D3. ...CONCLUSION: Vitamin D(3) is more effective than vitamin D( …
BACKGROUND: In patients with chronic kidney disease, vitamin D insufficiency is highly prevalent. It can be corrected by supplementat …
Effect of Vitamin D supplement use on serum concentrations of total 25OHD levels in elderly women.
Rapuri PB, Gallagher JC. Rapuri PB, et al. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):601-4. doi: 10.1016/j.jsbmb.2004.03.035. J Steroid Biochem Mol Biol. 2004. PMID: 15225846

A correlation of 0.91 (P < 0.001) was observed between the two methods for the serum total 25OHD measurement. The mean serum 25OHD level in Vitamin D(2) supplemented group was significantly higher than in unsupplemented group measured by HPLC

A correlation of 0.91 (P < 0.001) was observed between the two methods for the serum total 25OHD measurement. The mean s

Efficacy of plain cholecalciferol versus ergocalciferol in raising serum vitamin D level in Thai female healthcare workers.
Amphansap T, Therdyothin A, Stitkitti N, Nitiwarangkul L, Phiphobmongkol V. Amphansap T, et al. Osteoporos Sarcopenia. 2022 Dec;8(4):145-151. doi: 10.1016/j.afos.2022.12.001. Epub 2022 Dec 12. Osteoporos Sarcopenia. 2022. PMID: 36605166 Free PMC article.
Randomization allocated the participants into vitamin D2 group (N = 43), receiving ergocalciferol 20,000 IU weekly and vitamin D3 group (N = 40), receiving cholecalciferol 1000 IU daily for 12 months. ...While vitamin D3 could incr …
Randomization allocated the participants into vitamin D2 group (N = 43), receiving ergocalciferol 20,000 IU weekly and vita
25-Hydroxyvitamin D and 1,25-dihydroxyvitamin D of D2 and D3 origin in maternal and umbilical cord serum after vitamin D2 supplementation in human pregnancy.
Markestad T, Aksnes L, Ulstein M, Aarskog D. Markestad T, et al. Am J Clin Nutr. 1984 Nov;40(5):1057-63. doi: 10.1093/ajcn/40.5.1057. Am J Clin Nutr. 1984. PMID: 6333810
Serum concentrations of 25-hydroxyvitamin D (25-OHD) and 1,25-dihydroxyvitamin D [1,25-(OH)2D] of vitamin D2 and D3 origin were determined separately in 10 women before vitamin intake in early pregnancy, and repeated in maternal and cord seru
Serum concentrations of 25-hydroxyvitamin D (25-OHD) and 1,25-dihydroxyvitamin D [1,25-(OH)2D] of vitamin D2 and D3
Effect of cholecalciferol versus calcifediol on serum 25(OH)D concentrations: a systematic review with meta-analysis.
Bouden S, Ben Messaoud M, Saidane O, Rouached L, Ben Tekaya A, Mahmoud I, Tekaya R, Dziri C, Abdelmoula L. Bouden S, et al. Eur J Clin Nutr. 2025 Apr;79(4):296-305. doi: 10.1038/s41430-024-01520-x. Epub 2024 Oct 9. Eur J Clin Nutr. 2025. PMID: 39385006
At present, cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) are the most commonly used compounds. Supplementation with calcifediol (25OHD3) rather than vitamin D itself should also be considered for the treatment. We performe …
At present, cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) are the most commonly used compo …
Free versus total serum 25-hydroxyvitamin D in a murine model of colitis.
Larner DP, Jenkinson C, Chun RF, Westgate CSJ, Adams JS, Hewison M. Larner DP, et al. J Steroid Biochem Mol Biol. 2019 May;189:204-209. doi: 10.1016/j.jsbmb.2019.01.015. Epub 2019 Jan 30. J Steroid Biochem Mol Biol. 2019. PMID: 30710745 Free PMC article.
We have also shown in vitro that immune responses to 25OHD may depend on 'free' rather than total serum concentrations of 25OHD. To investigate the possible effects of free versus total 25OHD on anti-inflammatory immune responses in vivo we have …
We have also shown in vitro that immune responses to 25OHD may depend on 'free' rather than total serum concentrations of 2
The effect of somatostatin analogs on vitamin D and calcium concentrations in patients with acromegaly.
Ajmal A, Haghshenas A, Attarian S, Barake M, Tritos NA, Klibanski A, Miller KK, Nachtigall LB. Ajmal A, et al. Pituitary. 2014 Aug;17(4):366-73. doi: 10.1007/s11102-013-0514-0. Pituitary. 2014. PMID: 24002366 Review.
METHODS: 125 patients with acromegaly were studied. Serum calcium and 25OHD levels were compared prior to and after vitamin D supplementation between patients receiving versus not receiving SSA in whom medical therapy included pegvisomant and/or dopami …
METHODS: 125 patients with acromegaly were studied. Serum calcium and 25OHD levels were compared prior to and after vitamin
Exogenous versus endogenous recovery of 25-hydroxyvitamins D2 and D3 in human samples using high-performance liquid chromatography and the DiaSorin LIAISON Total-D Assay.
Horst RL. Horst RL. J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):180-2. doi: 10.1016/j.jsbmb.2010.03.010. Epub 2010 Mar 7. J Steroid Biochem Mol Biol. 2010. PMID: 20214981
However, exogenously added 25(OH)D2 and 25(OH)D3 were under-recovered by the DiaSorin Assay. NIST vitamin D standards containing serum from another species (horse) or exogenous 25(OH)D2 were similarly affected when using the DiaSorin Assay. Exog …
However, exogenously added 25(OH)D2 and 25(OH)D3 were under-recovered by the DiaSorin Assay. NIST vitamin D standards c …
Vitamin D supplementation in pregnancy: a systematic review.
Harvey NC, Holroyd C, Ntani G, Javaid K, Cooper P, Moon R, Cole Z, Tinati T, Godfrey K, Dennison E, Bishop NJ, Baird J, Cooper C. Harvey NC, et al. Health Technol Assess. 2014 Jul;18(45):1-190. doi: 10.3310/hta18450. Health Technol Assess. 2014. PMID: 25025896 Free PMC article.
(4) What is the optimal type (D2 or D3), dose, regimen and route for vitamin D supplementation in pregnancy? (5) Is supplementation with vitamin D in pregnancy likely to be cost-effective? ...SUBJECTS: pregnant women or pregnant women and their offspri …
(4) What is the optimal type (D2 or D3), dose, regimen and route for vitamin D supplementation in pregnancy? (5) Is sup …
27 results