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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 53
1946 93
1947 120
1948 102
1949 63
1950 123
1951 154
1952 127
1953 114
1954 132
1955 117
1956 110
1957 119
1958 109
1959 110
1960 98
1961 135
1962 117
1963 184
1964 247
1965 195
1966 170
1967 188
1968 242
1969 227
1970 256
1971 254
1972 224
1973 290
1974 278
1975 294
1976 236
1977 260
1978 216
1979 261
1980 248
1981 284
1982 288
1983 285
1984 291
1985 317
1986 276
1987 278
1988 267
1989 279
1990 316
1991 361
1992 362
1993 391
1994 462
1995 449
1996 467
1997 577
1998 585
1999 608
2000 661
2001 725
2002 723
2003 796
2004 805
2005 828
2006 794
2007 765
2008 843
2009 842
2010 884
2011 884
2012 867
2013 996
2014 969
2015 939
2016 886
2017 891
2018 875
2019 976
2020 1121
2021 1141
2022 1032
2023 897
2024 272

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32,329 results

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Page 1
Vitamin C: the known and the unknown and Goldilocks.
Padayatty SJ, Levine M. Padayatty SJ, et al. Oral Dis. 2016 Sep;22(6):463-93. doi: 10.1111/odi.12446. Epub 2016 Apr 14. Oral Dis. 2016. PMID: 26808119 Free PMC article. Review.
Vitamin C (Ascorbic Acid), the antiscorbutic vitamin, cannot be synthesized by humans and other primates, and has to be obtained from diet. ...Ascorbic acid is differentially accumulated by most tissues and body fluids. ...
Vitamin C (Ascorbic Acid), the antiscorbutic vitamin, cannot be synthesized by humans and other primates, and ha
Targeting cancer vulnerabilities with high-dose vitamin C.
Ngo B, Van Riper JM, Cantley LC, Yun J. Ngo B, et al. Nat Rev Cancer. 2019 May;19(5):271-282. doi: 10.1038/s41568-019-0135-7. Nat Rev Cancer. 2019. PMID: 30967651 Free PMC article. Review.
Over the past century, the notion that vitamin C can be used to treat cancer has generated much controversy. However, new knowledge regarding the pharmacokinetic properties of vitamin C and recent high-profile preclinical studies have revived interest …
Over the past century, the notion that vitamin C can be used to treat cancer has generated much controversy. However, new know …
Vitamin C in sepsis.
Kuhn SO, Meissner K, Mayes LM, Bartels K. Kuhn SO, et al. Curr Opin Anaesthesiol. 2018 Feb;31(1):55-60. doi: 10.1097/ACO.0000000000000549. Curr Opin Anaesthesiol. 2018. PMID: 29176375 Free PMC article. Review.
SUMMARY: In-vitro evidence supports a critical role for vitamin C in cellular mechanisms relevant to the pathophysiology of sepsis. However, whether this justifies therapeutic use of vitamin C in septic patients remains uncertain....
SUMMARY: In-vitro evidence supports a critical role for vitamin C in cellular mechanisms relevant to the pathophysiology of se …
The Pharmacokinetics of Vitamin C.
Lykkesfeldt J, Tveden-Nyborg P. Lykkesfeldt J, et al. Nutrients. 2019 Oct 9;11(10):2412. doi: 10.3390/nu11102412. Nutrients. 2019. PMID: 31601028 Free PMC article. Review.
The pharmacokinetics of vitamin C (vitC) is indeed complex. Regulated primarily by a family of saturable sodium dependent vitC transporters (SVCTs), the absorption and elimination are highly dose-dependent. ...
The pharmacokinetics of vitamin C (vitC) is indeed complex. Regulated primarily by a family of saturable sodium dependent vitC …
High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer.
Böttger F, Vallés-Martí A, Cahn L, Jimenez CR. Böttger F, et al. J Exp Clin Cancer Res. 2021 Oct 30;40(1):343. doi: 10.1186/s13046-021-02134-y. J Exp Clin Cancer Res. 2021. PMID: 34717701 Free PMC article. Review.
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer agent when administered intravenously and in high doses (high-dose IVC). ...In addition, an outlook on future implications of high-dose vitamin C in cancer treatmen …
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer agent when administered intravenously …
Pharmacology of vitamin C.
Sauberlich HE. Sauberlich HE. Annu Rev Nutr. 1994;14:371-91. doi: 10.1146/annurev.nu.14.070194.002103. Annu Rev Nutr. 1994. PMID: 7946525 Review.
A better understanding of the functions of ascorbic acid would help clarify the magnitude of the influence of this vitamin on health-related conditions. ...Human intervention trials may provide definitive and quantitative assessments of the role of vitamin
A better understanding of the functions of ascorbic acid would help clarify the magnitude of the influence of this vitamin on …
Vitamin C.
Lykkesfeldt J, Michels AJ, Frei B. Lykkesfeldt J, et al. Adv Nutr. 2014 Jan 1;5(1):16-8. doi: 10.3945/an.113.005157. Adv Nutr. 2014. PMID: 24425716 Free PMC article. No abstract available.
New oral liposomal vitamin C formulation: properties and bioavailability.
Łukawski M, Dałek P, Borowik T, Foryś A, Langner M, Witkiewicz W, Przybyło M. Łukawski M, et al. J Liposome Res. 2020 Sep;30(3):227-234. doi: 10.1080/08982104.2019.1630642. Epub 2019 Jul 2. J Liposome Res. 2020. PMID: 31264495
Vitamin C pharmacokinetics and low quantities in processed foodstuff, necessitates its continuous supplementation. ...Finally, the enhanced bioavailability of vitamin C from the formulation was demonstrated in the medical experiment....
Vitamin C pharmacokinetics and low quantities in processed foodstuff, necessitates its continuous supplementation. ...Finally,
Vitamin C pharmacokinetics: implications for oral and intravenous use.
Padayatty SJ, Sun H, Wang Y, Riordan HD, Hewitt SM, Katz A, Wesley RA, Levine M. Padayatty SJ, et al. Ann Intern Med. 2004 Apr 6;140(7):533-7. doi: 10.7326/0003-4819-140-7-200404060-00010. Ann Intern Med. 2004. PMID: 15068981 Free article.
BACKGROUND: Vitamin C at high concentrations is toxic to cancer cells in vitro. ...Because efficacy of vitamin C treatment cannot be judged from clinical trials that use only oral dosing, the role of vitamin C in cancer treatment should b …
BACKGROUND: Vitamin C at high concentrations is toxic to cancer cells in vitro. ...Because efficacy of vitamin C
Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance.
Levine M, Conry-Cantilena C, Wang Y, Welch RW, Washko PW, Dhariwal KR, Park JB, Lazarev A, Graumlich JF, King J, Cantilena LR. Levine M, et al. Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3704-9. doi: 10.1073/pnas.93.8.3704. Proc Natl Acad Sci U S A. 1996. PMID: 8623000 Free PMC article. Clinical Trial.
Determinants of the recommended dietary allowance (RDA) for vitamin C include the relationship between vitamin C dose and steady-state plasma concentration, bioavailability, urinary excretion, cell concentration, and potential adverse effects. ...Safe …
Determinants of the recommended dietary allowance (RDA) for vitamin C include the relationship between vitamin C
32,329 results
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