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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1993 1
1995 1
1998 2
2000 1
2001 5
2002 7
2003 4
2004 5
2005 8
2006 14
2007 9
2008 7
2009 11
2010 6
2011 5
2012 5
2013 9
2014 8
2015 4
2016 2
2017 6
2018 2
2019 3
2020 1
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Effect of vitamin K in bone metabolism and vascular calcification: A review of mechanisms of action and evidences.
Villa JKD, Diaz MAN, Pizziolo VR, Martino HSD. Villa JKD, et al. Crit Rev Food Sci Nutr. 2017 Dec 12;57(18):3959-3970. doi: 10.1080/10408398.2016.1211616. Crit Rev Food Sci Nutr. 2017. PMID: 27437760 Review.
Osteoporosis is a public health concern associated with an increased risk of bone fractures and vascular calcification. Vitamin K presents unique benefits on these issues, although understudied. The two main forms of vitamin K are phylloq …
Osteoporosis is a public health concern associated with an increased risk of bone fractures and vascular calcification. Vit
Vitamin K and osteoporosis: Myth or reality?
Palermo A, Tuccinardi D, D'Onofrio L, Watanabe M, Maggi D, Maurizi AR, Greto V, Buzzetti R, Napoli N, Pozzilli P, Manfrini S. Palermo A, et al. Metabolism. 2017 May;70:57-71. doi: 10.1016/j.metabol.2017.01.032. Epub 2017 Feb 4. Metabolism. 2017. PMID: 28403946 Review.
Vitamin K is a liposoluble vitamin. The predominant dietary form, phylloquinone or vitamin K1, is found in plants and green vegetables; whereas menaquinone, or vitamin K2, is endogenously synthesized by intestinal bacteria and includes se
Vitamin K is a liposoluble vitamin. The predominant dietary form, phylloquinone or vitamin K1, is found in plant
Immunomodulatory effect of vitamin K2: Implications for bone health.
Myneni VD, Mezey E. Myneni VD, et al. Oral Dis. 2018 Mar;24(1-2):67-71. doi: 10.1111/odi.12759. Oral Dis. 2018. PMID: 29480629 Free PMC article.
OBJECTIVE: In women with postmenopausal osteoporosis, vitamin K2 appears to decrease the incidence of hip, vertebral, and non-vertebral fractures. ...CONCLUSION: Vitamin K2 has immunomodulatory activities....
OBJECTIVE: In women with postmenopausal osteoporosis, vitamin K2 appears to decrease the incidence of hip, vertebral, and non- …
Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Huang ZB, et al. Osteoporos Int. 2015 Mar;26(3):1175-86. doi: 10.1007/s00198-014-2989-6. Epub 2014 Dec 17. Osteoporos Int. 2015. PMID: 25516361
Our results showed that vitamin K2 might play a role in maintaining the bone mineral density and in reducing the incidence of fractures for postmenopausal women with osteoporosis. ...As for the incidence of fractures, pooled analysis of the seve …
Our results showed that vitamin K2 might play a role in maintaining the bone mineral density and in reducing the incide …
Vitamin K2 (menaquinone-7) prevents age-related deterioration of trabecular bone microarchitecture at the tibia in postmenopausal women.
Rønn SH, Harsløf T, Pedersen SB, Langdahl BL. Rønn SH, et al. Eur J Endocrinol. 2016 Dec;175(6):541-549. doi: 10.1530/EJE-16-0498. Epub 2016 Sep 13. Eur J Endocrinol. 2016. PMID: 27625301 Clinical Trial.
OBJECTIVE: Clinical studies suggest that vitamin K2 protects against bone loss and fractures; however, its effect on bone quality has never been investigated. ...This suggests that vitamin MK-7 preserves trabecular bone structure a …
OBJECTIVE: Clinical studies suggest that vitamin K2 protects against bone loss and fractures; however, its effec …
Effectiveness of vitamin K2 on osteoporosis in adults with cerebral palsy.
Kodama Y, Okamoto Y, Kubota T, Hiroyama Y, Fukami H, Matsushita K, Kawano Y. Kodama Y, et al. Brain Dev. 2017 Nov;39(10):846-850. doi: 10.1016/j.braindev.2017.05.012. Epub 2017 Jun 16. Brain Dev. 2017. PMID: 28624135
BACKGROUND: Osteoporosis can lead to spontaneous fractures in adults with cerebral palsy (CP). Undercarboxylated osteocalcin (ucOC) is a useful marker for vitamin K insufficiency in osteoporosis. The primary objective of this study was to determine the effect …
BACKGROUND: Osteoporosis can lead to spontaneous fractures in adults with cerebral palsy (CP). Undercarboxylated osteocalcin (ucOC) i …
Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health.
Maresz K. Maresz K. Integr Med (Encinitas). 2015 Feb;14(1):34-9. Integr Med (Encinitas). 2015. PMID: 26770129 Free PMC article. Review.
Inadequate calcium intake can lead to decreased bone mineral density, which can increase the risk of bone fractures. Supplemental calcium promotes bone mineral density and strength and can prevent osteoporosis. ...Vitamin K, particularly …
Inadequate calcium intake can lead to decreased bone mineral density, which can increase the risk of bone fractures. Su …
Roles of Vitamins D and K, Nutrition, and Lifestyle in Low-Energy Bone Fractures in Children and Young Adults.
Karpiński M, Popko J, Maresz K, Badmaev V, Stohs SJ. Karpiński M, et al. J Am Coll Nutr. 2017 Jul;36(5):399-412. doi: 10.1080/07315724.2017.1307791. J Am Coll Nutr. 2017. PMID: 28686548
This review focuses on the role of vitamin K in combination with vitamin D and other factors in bone health. The current understanding is that maintaining bone health and prevention of low-energy fractures in any pediatric population incl …
This review focuses on the role of vitamin K in combination with vitamin D and other factors in bone health. The …
Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis.
Shiraki M, Shiraki Y, Aoki C, Miura M. Shiraki M, et al. J Bone Miner Res. 2000 Mar;15(3):515-21. doi: 10.1359/jbmr.2000.15.3.515. J Bone Miner Res. 2000. PMID: 10750566 Free article. Clinical Trial.
The control group (without treatment; n = 121) and the vitamin K2-treated group (n = 120), which received 45 mg/day orally vitamin K2, were followed for lumbar bone mineral density (LBMD; measured by dual-energy X-ray absorptiometry [DXA]) and o …
The control group (without treatment; n = 121) and the vitamin K2-treated group (n = 120), which received 45 mg/day orally …
[Bone and Nutrition. The association of vitamin K intake and bone health].
Kuwabara A, Tanaka K. Kuwabara A, et al. Clin Calcium. 2015 Jul;25(7):983-90. Clin Calcium. 2015. PMID: 26119310 Review. Japanese.
The association of vitamin K with bone mineral density has been reported in some previous cohort studies and intervention studies. ...Vitamin K intake greater than the current AI would be required for the bone health....
The association of vitamin K with bone mineral density has been reported in some previous cohort studies and interventi …
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