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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1965 2
1966 1
1967 1
1968 2
1969 6
1970 1
1971 2
1972 2
1973 3
1974 3
1975 2
1976 4
1978 3
1979 5
1980 2
1981 2
1982 5
1983 3
1984 2
1985 6
1986 1
1987 4
1988 1
1989 7
1990 7
1991 11
1992 13
1993 19
1994 26
1995 34
1996 40
1997 37
1998 56
1999 71
2000 90
2001 85
2002 80
2003 105
2004 110
2005 110
2006 108
2007 109
2008 100
2009 108
2010 113
2011 119
2012 158
2013 171
2014 156
2015 180
2016 131
2017 159
2018 151
2019 149
2020 116
2021 94
2022 110
2023 66
2024 11

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2,893 results

Results by year

Filters applied: Clinical Trial. Clear all
Page 1
Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease.
Manson JE, Cook NR, Lee IM, Christen W, Bassuk SS, Mora S, Gibson H, Gordon D, Copeland T, D'Agostino D, Friedenberg G, Ridge C, Bubes V, Giovannucci EL, Willett WC, Buring JE; VITAL Research Group. Manson JE, et al. N Engl J Med. 2019 Jan 3;380(1):33-44. doi: 10.1056/NEJMoa1809944. Epub 2018 Nov 10. N Engl J Med. 2019. PMID: 30415629 Free PMC article. Clinical Trial.
BACKGROUND: It is unclear whether supplementation with vitamin D reduces the risk of cancer or cardiovascular disease, and data from randomized trials are limited. ...A major cardiovascular event occurred in 805 participants (396 in the vitamin D group …
BACKGROUND: It is unclear whether supplementation with vitamin D reduces the risk of cancer or cardiovascular disease, and dat …
Vitamin D supplementation and major cardiovascular events: D-Health randomised controlled trial.
Thompson B, Waterhouse M, English DR, McLeod DS, Armstrong BK, Baxter C, Duarte Romero B, Ebeling PR, Hartel G, Kimlin MG, Rahman ST, van der Pols JC, Venn AJ, Webb PM, Whiteman DC, Neale RE. Thompson B, et al. BMJ. 2023 Jun 28;381:e075230. doi: 10.1136/bmj-2023-075230. BMJ. 2023. PMID: 37380191 Free PMC article. Clinical Trial.
OBJECTIVE: To investigate whether supplementing older adults with monthly doses of vitamin D alters the incidence of major cardiovascular events. DESIGN: Randomised, double blind, placebo controlled trial of monthly vitamin D (the D-Health Trial). ...The medi …
OBJECTIVE: To investigate whether supplementing older adults with monthly doses of vitamin D alters the incidence of major cardiov
Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial: a randomized controlled trial.
Virtanen JK, Nurmi T, Aro A, Bertone-Johnson ER, Hyppönen E, Kröger H, Lamberg-Allardt C, Manson JE, Mursu J, Mäntyselkä P, Suominen S, Uusitupa M, Voutilainen A, Tuomainen TP, Hantunen S. Virtanen JK, et al. Am J Clin Nutr. 2022 May 1;115(5):1300-1310. doi: 10.1093/ajcn/nqab419. Am J Clin Nutr. 2022. PMID: 34982819 Free PMC article. Clinical Trial.
BACKGROUND: Vitamin D insufficiency is associated with risks of cardiovascular diseases (CVD) and cancer in observational studies, but evidence for benefits with vitamin D supplementation is limited. ...The study had 3 arms: placebo, 1600 IU/day, or 3200 IU/d …
BACKGROUND: Vitamin D insufficiency is associated with risks of cardiovascular diseases (CVD) and cancer in observational stud …
Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.
Sesso HD, Manson JE, Aragaki AK, Rist PM, Johnson LG, Friedenberg G, Copeland T, Clar A, Mora S, Moorthy MV, Sarkissian A, Carrick WR, Anderson GL; COSMOS Research Group. Sesso HD, et al. Am J Clin Nutr. 2022 Jun 7;115(6):1490-1500. doi: 10.1093/ajcn/nqac055. Am J Clin Nutr. 2022. PMID: 35294962 Free PMC article. Clinical Trial.
The primary outcome was a composite of confirmed incident total cardiovascular events, including myocardial infarction (MI), stroke, coronary revascularization, cardiovascular death, carotid artery disease, peripheral artery surgery, and unstable angina. ...Potentia …
The primary outcome was a composite of confirmed incident total cardiovascular events, including myocardial infarction (MI), stroke, …
Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes.
Gaede P, Vedel P, Larsen N, Jensen GV, Parving HH, Pedersen O. Gaede P, et al. N Engl J Med. 2003 Jan 30;348(5):383-93. doi: 10.1056/NEJMoa021778. N Engl J Med. 2003. PMID: 12556541 Free article. Clinical Trial.
BACKGROUND: Cardiovascular morbidity is a major burden in patients with type 2 diabetes. ...METHODS: The primary end point of this open, parallel trial was a composite of death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, revasculariz …
BACKGROUND: Cardiovascular morbidity is a major burden in patients with type 2 diabetes. ...METHODS: The primary end point of this op …
The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease.
Manson JE, Bassuk SS, Lee IM, Cook NR, Albert MA, Gordon D, Zaharris E, Macfadyen JG, Danielson E, Lin J, Zhang SM, Buring JE. Manson JE, et al. Contemp Clin Trials. 2012 Jan;33(1):159-71. doi: 10.1016/j.cct.2011.09.009. Epub 2011 Oct 2. Contemp Clin Trials. 2012. PMID: 21986389 Free PMC article. Clinical Trial.
Data from laboratory studies, observational research, and/or secondary prevention trials suggest that vitamin D and marine omega-3 fatty acids may reduce risk for cancer or cardiovascular disease (CVD), but primary prevention trials with adequate dosing in general p …
Data from laboratory studies, observational research, and/or secondary prevention trials suggest that vitamin D and marine omega-3 fa …
Effect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults: The DO-HEALTH Randomized Clinical Trial.
Bischoff-Ferrari HA, Vellas B, Rizzoli R, Kressig RW, da Silva JAP, Blauth M, Felson DT, McCloskey EV, Watzl B, Hofbauer LC, Felsenberg D, Willett WC, Dawson-Hughes B, Manson JE, Siebert U, Theiler R, Staehelin HB, de Godoi Rezende Costa Molino C, Chocano-Bedoya PO, Abderhalden LA, Egli A, Kanis JA, Orav EJ; DO-HEALTH Research Group. Bischoff-Ferrari HA, et al. JAMA. 2020 Nov 10;324(18):1855-1868. doi: 10.1001/jama.2020.16909. JAMA. 2020. PMID: 33170239 Free PMC article. Clinical Trial.
IMPORTANCE: The benefits of vitamin D, omega-3 fatty acids, and exercise in disease prevention remain unclear. ...INTERVENTIONS: Participants were randomized to 3 years of intervention in 1 of the following 8 groups: 2000 IU/d of vitamin D3, 1 g/d of omega-3s, and a …
IMPORTANCE: The benefits of vitamin D, omega-3 fatty acids, and exercise in disease prevention remain unclear. ...INTERVENTIONS: Part …
Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial.
Sevransky JE, Rothman RE, Hager DN, Bernard GR, Brown SM, Buchman TG, Busse LW, Coopersmith CM, DeWilde C, Ely EW, Eyzaguirre LM, Fowler AA, Gaieski DF, Gong MN, Hall A, Hinson JS, Hooper MH, Kelen GD, Khan A, Levine MA, Lewis RJ, Lindsell CJ, Marlin JS, McGlothlin A, Moore BL, Nugent KL, Nwosu S, Polito CC, Rice TW, Ricketts EP, Rudolph CC, Sanfilippo F, Viele K, Martin GS, Wright DW; VICTAS Investigators. Sevransky JE, et al. JAMA. 2021 Feb 23;325(8):742-750. doi: 10.1001/jama.2020.24505. JAMA. 2021. PMID: 33620405 Free PMC article. Clinical Trial.
IMPORTANCE: Sepsis is a common syndrome with substantial morbidity and mortality. A combination of vitamin C, thiamine, and corticosteroids has been proposed as a potential treatment for patients with sepsis. OBJECTIVE: To determine whether a combination of vitamin
IMPORTANCE: Sepsis is a common syndrome with substantial morbidity and mortality. A combination of vitamin C, thiamine, and corticost …
Cardiovascular and Cerebrovascular Response to RedBull Energy Drink Intake in Young Adults.
Costa R, Rocha C, Santos H. Costa R, et al. Anatol J Cardiol. 2023 Jan;27(1):19-25. doi: 10.14744/AnatolJCardiol.2022.2315. Anatol J Cardiol. 2023. PMID: 36680443 Free PMC article. Clinical Trial.
BACKGROUND: Energy drinks contain caffeine, taurine, sucrose, vitamins, and other amino acids. The dosage of these varies depending on the drink chosen. ...This study analyzed the cardio- and cerebrovascular responses after consumption of an energy drink - RedBull - under …
BACKGROUND: Energy drinks contain caffeine, taurine, sucrose, vitamins, and other amino acids. The dosage of these varies depending o …
Background and rationale behind the SU.VI.MAX Study, a prevention trial using nutritional doses of a combination of antioxidant vitamins and minerals to reduce cardiovascular diseases and cancers. SUpplementation en VItamines et Mineraux AntioXydants Study.
Hercberg S, Galan P, Preziosi P, Roussel AM, Arnaud J, Richard MJ, Malvy D, Paul-Dauphin A, Briançon S, Favier A. Hercberg S, et al. Int J Vitam Nutr Res. 1998;68(1):3-20. Int J Vitam Nutr Res. 1998. PMID: 9503043 Review.
The "SUpplementation en VItamines et MinerauxAntioXydants" (SU.VI.MAX) study is a randomized double-blind, placebo-controlled, primary prevention trial designed to test the efficacy of daily supplementation with antioxidant vitamins (vitamin C, 120 mg; vit
The "SUpplementation en VItamines et MinerauxAntioXydants" (SU.VI.MAX) study is a randomized double-blind, placebo-controlled, primar …
2,893 results